KEGG   ENZYME: 5.4.3.9
Entry
EC 5.4.3.9                  Enzyme                                 
Name
glutamate 2,3-aminomutase
Class
Isomerases;
Intramolecular transferases;
Transferring amino groups
Sysname
L-glutamate 2,3-aminomutase
Reaction(IUBMB)
L-glutamate = 3-aminopentanedioate [RN:R10153]
Reaction(KEGG)
R10153
Substrate
L-glutamate [CPD:C00025]
Product
3-aminopentanedioate [CPD:C05574]
Comment
This enzyme is a member of the 'AdoMet radical' (radical SAM) family. It contains pyridoxal phosphate and a [4Fe-4S] cluster, which is coordinated by 3 cysteines and binds an exchangeable S-adenosyl-L-methionine molecule. During the reaction cycle, the AdoMet forms a 5'-deoxyadenosyl radical, which is regenerated at the end of the reaction.
History
EC 5.4.3.9 created 2012
Orthology
K19814  glutamate 2,3-aminomutase
Genes
DFLDFE_1413(kamA)
CCBClocel_2678
CACECACET_c07510(kamA1)
CFMBJL90_09905
CSEPCP523_02425(eam)
AMTAmet_2738
PBIFKXZ80_10945(eam)
HSCHVS_09740(eam)
CSSCst_c09560(kamA1)
CSDClst_0916
CSHClosa_2267
CDFCD630_22520(kamA)
PDCCDIF630_02487(eam)
CDCCD196_2109(kamA)
CDLCDR20291_2152(kamA)
PDFCD630DERM_22520(kamA)
PSORRSJ16_12680
ROCHF520_03610(eam)
TEBT8CH_0897(eam)
SWOSwol_1121
SLPSlip_1437
SALQSYNTR_0636
CALKHUE98_06730(eam)
DSYDSY4027
DHDDhaf_1337
DDHDesde_0983 Desde_1272
DDLDesdi_1057
DMTDESME_03065 DESME_04100
SGYSgly_2707
DORDesor_0517
DAIDesaci_0733
DMIDesmer_0614
DEDDHBDCA_p1654
DECDCF50_p1663
DRSDEHRE_12100
DCADesca_1530
PTHPTH_0616(KamA)
DRMDred_2148
DRUDesru_1637
DFGB0537_10675
DAEDtox_0599 Dtox_2931
DKUDesku_1193
DAUDaud_1068
TJRTherJR_1812
DGIDesgi_3039
ALKAJ0B03_02685
ACAEHYG86_17310(eam)
CTHMCFE_1096 CFE_1097
TTETTE1204(KamA2)
CHYCHY_2479
MTAMoth_0457
MTHOMOTHE_c03930(eam)
MTHZMOTHA_c04820(eam)
ADGAdeg_1408
TPZTph_c22230(kamA)
GEKkuro4_08900 kuro4_08940
CSCCsac_0232
ATEAthe_2274
COBCOB47_2039
CHDCalhy_0483
COWCalow_1972
CKICalkr_2290
CLCCalla_0160
CKNCalkro_0356
CCHAELD05_01180(eam)
CDIACaldiYA01_03110(eam)
CNAGOTJ99_002263(eam)
NTHNther_1768
NCDACONDI_00898(eam_2)
MHAPJFY71_03305
CADCuri_c04320(kamA)
CAZOG3A45_02895(eam)
XCLG4Z02_00090
MMILsm9_1912
MEYETL18_07795
MEZMtc_0931
 » show all
Reference
1  [PMID:17222594]
  Authors
Ruzicka FJ, Frey PA
  Title
Glutamate 2,3-aminomutase: a new member of the radical SAM superfamily of enzymes.
  Journal
Biochim Biophys Acta 1774:286-96 (2007)
DOI:10.1016/j.bbapap.2006.11.008
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.4.3.9
IUBMB Enzyme Nomenclature: 5.4.3.9
ExPASy - ENZYME nomenclature database: 5.4.3.9
BRENDA, the Enzyme Database: 5.4.3.9

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