KEGG   ENZYME: 5.4.99.1
Entry
EC 5.4.99.1                 Enzyme                                 
Name
methylaspartate mutase;
glutamate mutase;
glutamic mutase;
glutamic isomerase;
glutamic acid mutase;
glutamic acid isomerase;
methylaspartic acid mutase;
beta-methylaspartate-glutamate mutase;
glutamate isomerase
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
Sysname
L-threo-3-methylaspartate carboxy-aminomethylmutase
Reaction(IUBMB)
L-threo-3-methylaspartate = L-glutamate [RN:R00262]
Reaction(KEGG)
R00262
Substrate
L-threo-3-methylaspartate [CPD:C03618]
Product
L-glutamate [CPD:C00025]
Comment
Requires a cobamide coenzyme.
History
EC 5.4.99.1 created 1961
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
ec00660  C5-Branched dibasic acid metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K01846  methylaspartate mutase sigma subunit
K19268  methylaspartate mutase epsilon subunit
Genes
ECEZ0893 Z0895
ECSECs_0762 ECs_0764
ECFECH74115_0830(mutE) ECH74115_0832(mamA)
ETWECSP_0780 ECSP_0782
ELXCDCO157_0742 CDCO157_0744
ECOOECRM13514_0751 ECRM13514_0753
ECOHECRM13516_0698 ECRM13516_0700
ECGE2348C_0612
EOKG2583_0893(mutE) G2583_0895(mamA)
ELRECO55CA74_04345 ECO55CA74_04355
ECMEcSMS35_0750(mutE) EcSMS35_0752(mamA)
EUMECUMN_0815 ECUMN_0817
ECTECIAI39_0702 ECIAI39_0704
EOCCE10_0731(mutE) CE10_0733(mamA)
ELOEC042_0754(mutE) EC042_0756(mamA)
EFEEFER_2375 EFER_2377
EMAC1192_08680 C1192_08690
ESZFEM44_18115 FEM44_18125
SESSARI_02198 SARI_02200
SDYSDY_0674 SDY_0676
SDZAsd1617_00850 Asd1617_00852
ESHC1N69_07905 C1N69_07915
KOXKOX_14670 KOX_14680
KOEA225_1757 A225_1759
KOYJ415_22855 J415_22865
KOMHR38_13445 HR38_13455
KOKKONIH1_08645 KONIH1_08655
KOCAB185_27480 AB185_27490
KLLBJF97_09015 BJF97_09025
KLWDA718_19605 DA718_19615
KGRJJJ10_19535 JJJ10_19545
CKOCKO_02416 CKO_02418
CFDCFNIH1_13775 CFNIH1_13785
CBRAA6J81_09335 A6J81_09345
CWECO701_15150 CO701_15160
CYOCD187_16550 CD187_16560
CPOTFOB25_04000 FOB25_04010
CFQC2U38_07705 C2U38_07715
CSEDJY391_14735 JY391_14745
CAMAF384_03290 F384_03300
CAFAL524_18985 AL524_18995
CIFAL515_08255 AL515_08265
CFARCI104_08020 CI104_08030
CIRC2U53_17240 C2U53_17250
CIEAN232_22690 AN232_22700
CPARCUC49_03405 CUC49_03415
CTELGBC03_21970 GBC03_21980
CITZE4Z61_09945 E4Z61_09955
CARSE1B03_08820 E1B03_08830
ESCEntcl_1733 Entcl_1735
KLEAO703_13270 AO703_13280
BUFD8682_20790 D8682_20800
BFTMNO13_05015 MNO13_05025
YREHEC60_20880 HEC60_20890
YENYE4040(mamA) YE4042(mutE)
YEPYE105_C3760 YE105_C3762
YEYY11_31531 Y11_31551
YELLC20_00183 LC20_00185
YEWCH47_3689 CH47_3691(mamA)
YETCH48_1492(mamA) CH48_1494
YEFFORC2_0152 FORC2_0154
YEEYE5303_38741(mamA) YE5303_38761(mutE)
YALAT01_1095(mamA) AT01_1097
YINCH53_310(mamA) CH53_312
YROCH64_1337(mamA) CH64_1339
YHID5F51_21345 D5F51_21355
YCAF0T03_21030 F0T03_21040
MMKMU9_1020 MU9_1022
HAVAT03_08655 AT03_08665
OPODSM2777_13865 DSM2777_13875
PGBH744_2c2551
PPZH045_12400 H045_12405
PXNHU772_021530 HU772_021535
PHVHU739_016540 HU739_016555
PPRGHU725_012515 HU725_012530
PANHHU763_000905 HU763_000920
PMUYKSS95_06290 KSS95_06295
THIPN838_23515
GAIIMCC3135_17395(glmE) IMCC3135_17400(glmS_1)
BCAIK788_0005647 K788_0005651
SULGFJR48_02175 FJR48_02180
SMULSMUL_1980(glmE) SMUL_1981(mamA)
SHALSHALO_1754 SHALO_1755
SULSSdiek1_1845 Sdiek1_1846
SULJSJPD1_1761 SJPD1_1762
ANTArnit_1894 Arnit_1895
AELLAELL_1273(gmuE) AELL_1274(gmuS)
AAQIAAQM_1184(gmuE) AAQM_1185(gmuS)
ASUIASUIS_1231(gmuE) ASUIS_1232(gmuS)
ACLOACLO_1443(gmuS) ACLO_1444(gmuE)
AVPAVENP_1474(gmuE) AVENP_1475(gmuS)
ADZADFLV_1385(gmuE) ADFLV_1386(gmuS)
ALKALEK_2065(gmuS) ALEK_2066(gmuE)
ALPLPB137_08455 LPB137_08460
AHSAHALO_1531(gmuS) AHALO_1532(gmuE)
AMYTAMYT_1636(gmuS) AMYT_1637(gmuE)
AMARAMRN_1554(gmuS) AMRN_1555(gmuE)
ACAAACAN_1584(gmuS) ACAN_1585(gmuE)
AMOLAMOL_1598(gmuS)
APAIAPAC_1387(gmuE) APAC_1388(gmuS)
HBVABIV_1442(gmuS) ABIV_1443(gmuE)
HEBRAEBR_1480(gmuE) AEBR_1481(gmuS)
PACOAACT_1414(gmuE) AACT_1415(gmuS)
ARCABLL_1388 ABLL_1389
SUNSUN_1085 SUN_1086
SLHYH65_04365 YH65_04370
CFUSCYFUS_003159 CYFUS_003162
HOHHoch_4358 Hoch_4361 Hoch_6166 Hoch_6168
NAFGQ61_08180
RIDRIdsm_04434(mamA)
PPANESD82_15265 ESD82_15270
GFUKM031_18920 KM031_18925
RMFD5E69_05120 D5E69_05125
TUMCBW65_03510 CBW65_03520
TABCIG75_03335 CIG75_03345
CTCCTC_02565(mutE) CTC_02568(mutS)
CTETBN906_02815(mutE) BN906_02817(mutS_3)
CKLCKL_0302(mutE)
CKRCKR_0253
CLJCLJU_c40620(mutE) CLJU_c40640(mutS4)
CAHCAETHG_1905 CAETHG_1907(glmS)
CSQCSCA_4325 CSCA_4327
CACECACET_c34420(glmE) CACET_c34440(glmS1)
CCKCcar_17560 Ccar_17565 Ccar_19620 Ccar_19630
CEUA7L45_08005 A7L45_08015
CFMBJL90_02580 BJL90_02590
CARGRSJ17_03840 RSJ17_03850
CDRKB9W14_23405 B9W14_23415
CCOHSAMEA4530647_2260(mutE) SAMEA4530647_2262(mutS_3)
CLOSDMR38_20140 DMR38_20150
CCAAKQH81_15285 KQH81_15295
AMTAmet_3415 Amet_3416
HHWNCTC503_02398(mutE) NCTC503_02400(mutS_4)
CALEFDN13_04645 FDN13_04655
BYLA4V09_10275 A4V09_10285
BHANCGC63_11300 CGC63_11310
BLAUDQQ01_11170 DQQ01_11180
BPROPMF13cell1_03214(glmS_2) PMF13cell1_03216(glmE)
EACEAL2_808p05900(glmE) EAL2_808p05920(mamA)
TEMJW646_17955 JW646_17965
TGCL0P85_10060 L0P85_10070(glmS)
PBQC3V37_01030 C3V37_01040
DSYDSY3234 DSY3236
DHDDhaf_4401 Dhaf_4403
DDHDesde_3780 Desde_3782
DMTDESME_13820 DESME_13830
DORDesor_5276 Desor_5278
DAIDesaci_4374 Desaci_4376
DMIDesmer_4262 Desmer_4264
DCADesca_0601 Desca_0603
PTHPTH_2419(Sbm) PTH_2420
DRMDred_2690 Dred_2692
DRUDesru_0924 Desru_0926
DFGB0537_13820 B0537_13830
AACXDEACI_0129 DEACI_0131
VGUHYG85_02140 HYG85_02150
VPYHZI73_09935 HZI73_09945
ACAEHYG86_02380 HYG86_02390
CTHMCFE_0616 CFE_0618
FMSM1R53_04060(glmS) M1R53_04070
EUUADJ67_05930 ADJ67_05940
CHYCHY_0307(mamA) CHY_0309(mutE)
TPZTph_c20260(glmE) Tph_c20280(mamA)
GEKkuro4_25050
TEPTepRe1_0112 TepRe1_0114
TAETepiRe1_0117(mamA) TepiRe1_0119(glmE)
NTHNther_1955
NCDACONDI_00354(glmE)
HORHore_15440 Hore_15460
HPKHprae_1851 Hprae_1853
HALSD7D81_15600 D7D81_15610
IFNGM661_12740 GM661_12750
AARAcear_0477 Acear_0479
HHLHalha_1650 Halha_1652
AFTBBF96_08385 BBF96_08395
ECOUM1R54_02155 M1R54_02165(glmS)
PUFUFO1_3074 UFO1_3076
PFTJBW_01513 JBW_01515
MANAMAMMFC1_00633(glmE) MAMMFC1_00635(mamA)
STEDSPTER_10660(glmS_2) SPTER_10680(glmE)
MANRMPAN_001690(glmE) MPAN_001710
MBJKQ51_00876(mamA) KQ51_00878(glmE)
TBMBK010_00850 BK010_00860
TBZBK011_00740 BK011_00750
TBKHF295_06605 HF295_06615
CEECENDO_08575
NBRO3I_015470 O3I_015485
NOZDMB37_03315 DMB37_03330
NODFOH10_23480 FOH10_23495
RHBNY08_3253 NY08_3254
SSXSACTE_5574 SACTE_5575
SHYSHJG_1663 SHJG_1664 SHJG_1909 SHJG_1910
SHOSHJGH_1427 SHJGH_1428 SHJGH_1674 SHJGH_1675
SMALSMALA_8119 SMALA_8120
SSOII1A49_44320 I1A49_44325
SCTSCAT_p1371 SCAT_p1372
SCYSCATT_p03530 SCATT_p03540
SFASfla_0985 Sfla_0986
SBHSBI_00835 SBI_00836
SVESVEN_6011
SALSSLNWT_0920 SLNWT_0922
STRPF750_5862 F750_5863
SGUSGLAU_07145 SGLAU_07150
SVTSVTN_01955 SVTN_01960
SLDT261_1325 T261_1326
SLCSL103_12535 SL103_12540
SPRISPRI_3471 SPRI_3472
SCXAS200_00925 AS200_00930 AS200_02925
SRWTUE45_pSRc_0422(TUE45_pSRTUE45c_0422) TUE45_pSRc_0423(mutE)
SRNA4G23_02370(mutE) A4G23_02371
SKYD0C37_02110 D0C37_02115
SPLULK06_031960
SNWBBN63_01150 BBN63_01155
SGVB1H19_35590 B1H19_35605
SLAUSLA_0040 SLA_0041
SLXSLAV_09270 SLAV_09275(mutE)
STROSTRMOE7_07560
SFKKY5_0483c KY5_0484c KY5_6021 KY5_6022
SRJSRO_1514 SRO_1517 SRO_1559 SRO_1560 SRO_6326 SRO_6327
SQZFQU76_02700 FQU76_02705
SNQCP978_29015 CP978_29020 CP978_34535 CP978_34540
STIRDDW44_27525 DDW44_27530
SKACP970_10805 CP970_10810 CP970_40355 CP970_40360
SNKCP967_24780 CP967_24785
SRKFGW37_02645
SGFHEP81_01701 HEP81_01704(glmS_1) HEP81_01745 HEP81_01746 HEP81_06675 HEP81_06676
SCAVCVT27_19870 CVT27_19875
SSUBCP968_02000 CP968_02005 CP968_02845 CP968_02850
SCINCP977_30265 CP977_30270
STSUB7R87_02790 B7R87_02795
SGXH4W23_33330 H4W23_33335 H4W23_36090 H4W23_36095
SBROGQF42_08735 GQF42_08740
SATAC5746_38280 C5746_38285 C5746_40300 C5746_40305
SCYGS1361_29190(glmE) S1361_29195
SLIAHA039_02610 HA039_02615
SFBCP974_12990 CP974_12995
SMOBJ7W19_32095 J7W19_32100
SXNIAG42_37135 IAG42_37140
SGJIAG43_30775 IAG43_30780
SANUK7396_07635 K7396_07640
STRYEQG64_20625
SDDD9753_09090 D9753_09095 D9753_32055 D9753_32060
SINEKI385_04880
SLFJEQ17_40480 JEQ17_40485
KABB7C62_02445 B7C62_02450
KITCFP65_4220
YIALO772_27850 LO772_27855
NALB005_1646 B005_1647 B005_2525 B005_2526
NGVCDO52_23280 CDO52_23285
AMDAMED_4749 AMED_4750 AMED_4797 AMED_4798
AMNRAM_24175 RAM_24180 RAM_24420 RAM_24425
AMMAMES_4690 AMES_4691 AMES_4738 AMES_4739
AMZB737_4690 B737_4691 B737_4738 B737_4739
AOIAORI_3154 AORI_3155
AJAAJAP_23585 AJAP_23590
AMYCCU254_30195 CU254_30200
AMYYYIM_11500 YIM_11505(mutE)
AORISD37_16085 SD37_16090
AACDLWP59_31705 LWP59_31710
SSYIEKG83_33210 EKG83_33215
KALKALB_1482
PMADBAY61_17735 BAY61_17740
SAQSare_2951 Sare_2952
MTUACSH63_31850 CSH63_31855
MICHFJK98_01270 FJK98_01275
MCABHXZ27_06655 HXZ27_06660
ACTNL083_4626
AFSAFR_18510 AFR_18515
AIHAiant_25720 Aiant_25730
PLABC6361_01930 C6361_01935
PLATC6W10_19735 C6W10_19740
PRYPrubr_63420 Prubr_63440
NHYJQS43_06740 JQS43_06745
CAICaci_6322 Caci_6323
AEYCDG81_18240 CDG81_18245
ABAOBEQ56_05605 BEQ56_05615
TDETDE_1023(mamA) TDE_2236(glmE)
TPITREPR_1301(mamA) TREPR_1303
TPEDTPE_1063(mamA) TPE_1191(glmE)
TPKJO40_00630 JO40_01080
SCDSpica_1656 Spica_1658
FNUFN1853 FN1855
FNCHMPREF0946_01601 HMPREF0946_01603
FNTHMPREF0405_01377 HMPREF0405_01379
FUSHMPREF0409_01381 HMPREF0409_01383
FNEFSDG_01986 FSDG_01988
FHWRN87_00330 RN87_00340
FPDCTM68_06790 CTM68_06800
FVAFV113G1_25170 FV113G1_25190
FULC4N20_01150 C4N20_01160
FMOC4N19_13175 C4N19_13185
FGOC4N16_07540
FNFBSQ88_07220
FPEIC4N17_12425 C4N17_12435
FCII6I83_03080 I6I83_03090
IPOIlyop_0553 Ilyop_0555
CSOMMKD34_06455 MKD34_06465(glmS)
PAHPoras_1167 Poras_1169
PCRENCTC12858_01577(mamA) NCTC12858_01579(mutE)
PSOECE91St14_10320(glmS) CE91St14_10340
PETPEIBARAKI_4285 PEIBARAKI_4287
TOHBCB71_00040 BCB71_00050
PITPIN17_0464(mamA) PIN17_0466
PNIJ5A59_01345 J5A59_01355
CPICpin_3405
DTHDICTH_1230 DICTH_1232(mamA)
DTUDtur_1345 Dtur_1347
HALVNG_2286G(mamA) VNG_2288G(mamB)
HSLOE_4204F(mamA) OE_4206F(mamB)
HAGSJT689_10580(mamA) JT689_10585
HABOJRZ79_08955(mamA) JRZ79_08960
HANRLJ422_09230(mamA) LJ422_09235
HALXM0R89_18070(glmS) M0R89_18075
HMArrnAC0684(mamA1) rrnAC0685(mamB) rrnAC0984(mamA2)
HHIHAH_1337(mamA1) HAH_1338(mamB) HAH_1611(mamA2)
HHNHISP_06845 HISP_06850 HISP_08220
HABSG26_14690 SG26_14695 SG26_16020
HTABVU17_06515 BVU17_06520 BVU17_07795
HALJG9465_06705 G9465_08565 G9465_08570
HSINKDQ40_05390 KDQ40_06780 KDQ40_06785
HMUHmuk_2980 Hmuk_2981
HALZE5139_02175 E5139_02180
HALLLC1Hm_2317(glmS3) LC1Hm_2318(glmE)
HAZPGBQ70_02175 GBQ70_02180
HRRHZS55_20000 HZS55_20005
HPELHZS54_23500 HZS54_23505
HTUHtur_1593 Htur_1594 Htur_2791
HDABB347_04025 BB347_04030 BB347_09595
HSALJMJ58_00665 JMJ58_00670 JMJ58_14490
HLOJ0X27_02310 J0X27_02315 J0X27_13465
HAKZJ0X25_02145 J0X25_14775 J0X25_14780
NMGNmag_3334(mamA) Nmag_3335(mamB)
HXAHalxa_3155 Halxa_3156
NATNJ7G_2163 NJ7G_3292 NJ7G_3293
NPENatpe_0789 Natpe_2593 Natpe_2594
NVRFEJ81_04070 FEJ81_11895 FEJ81_11900
NPLFGF80_06750 FGF80_10935 FGF80_10940
NAYHYG81_06915 HYG81_14705 HYG81_14710
HALYHYG82_09960 HYG82_17325 HYG82_17330
HJTDVR14_02950 DVR14_02955 DVR14_13275
NGENatgr_2183 Natgr_2184 Natgr_2479 Natgr_3387 Natgr_3388
HRUHalru_1551 Halru_1552
NOUNatoc_1512 Natoc_1513
SALIL593_04675 L593_04680
HLRHALLA_07390 HALLA_10850 HALLA_10855
HLCCHINAEXTREME16090 CHINAEXTREME16095
NAJB1756_12005 B1756_12010 B1756_13765
NAGAArcMg_1648 AArcMg_1649 AArcMg_2813
NANAArc1_0893 AArc1_1990 AArc1_1991
NBGDV706_10095 DV706_12995 DV706_13000
NASGCU68_02000 GCU68_13740 GCU68_13745
SAWLNGM29_08785 NGM29_08790(glmS)
 » show all
Reference
1  [PMID:14245371]
  Authors
BARKER HA, ROOZE V, SUZUKI F, IODICE AA.
  Title
THE GLUTAMATE MUTASE SYSTEM. ASSAYS AND PROPERTIES.
  Journal
J Biol Chem 239:3260-6 (1964)
Reference
2  [PMID:16590408]
  Authors
Weissbach H, Toohey J, Barker HA.
  Title
ISOLATION AND PROPERTIES OF B(12) COENZYMES CONTAINING BENZIMIDAZOLE OR DIMETHYLBENZIMIDAZOLE.
  Journal
Proc Natl Acad Sci U S A 45:521-5 (1959)
DOI:10.1073/pnas.45.4.521
Other DBs
ExplorEnz - The Enzyme Database: 5.4.99.1
IUBMB Enzyme Nomenclature: 5.4.99.1
ExPASy - ENZYME nomenclature database: 5.4.99.1
BRENDA, the Enzyme Database: 5.4.99.1
CAS: 9032-97-7

DBGET integrated database retrieval system