KEGG   ENZYME: 5.4.99.17
Entry
EC 5.4.99.17                Enzyme                                 
Name
squalene---hopene cyclase
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
Sysname
squalene mutase (cyclizing, hop-22(29)-ene-forming)
Reaction(IUBMB)
squalene = hop-22(29)-ene [RN:R07322]
Reaction(KEGG)
R07322
Substrate
squalene [CPD:C00751]
Product
hop-22(29)-ene [CPD:C06310]
Comment
The enzyme also produces the cyclization product hopan-22-ol by addition of water (cf. EC 4.2.1.129, squalene-hopanol cyclase). Hopene and hopanol are formed at a constant ratio of 5:1.
History
EC 5.4.99.17 created 2002, modified 2011
Pathway
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K06045  squalene-hopene/tetraprenyl-beta-curcumene cyclase
Genes
MGRMGG_00792
PPEIPpBr36_08342
FOXFOXG_17453
PLJVFPFJ_10743
CHIGCH63R_11561
PFYPFICI_08232
PSCOLY89DRAFT_588691
AFMAFUA_5G00110 AFUA_7G00260 AFUA_7G00300
ACTACLA_024280
NFINFIA_112770 NFIA_112850
AORAO090038000098
ANGANI_1_2222014(An01g01290)
AFVAFLA_012369
ALUCAKAW2_30529A
ACHEACHE_80355A
PCSPc22g24190
AJEHCAG_06936
ADLAURDEDRAFT_54410
FAUFraau_0755 Fraau_3212
DJAHY57_12650
DYEEO087_12870(shc)
DCSISN74_17650(shc)
DTLH8F01_19305(shc)
AVNAvin_20760
AVLAvCA_20760
AVDAvCA6_20760
TTUTERTU_3240(shc)
ASIPAQUSIP_21910(shc)
LFALFA_3651(shc)
MCAMCA0812(sqhC)
METUGNH96_04640(shc)
MMTMetme_2461 Metme_3474
MDNJT25_015465 JT25_019085
MDHAYM39_06140
MKOMKLM6_1250 MKLM6_1920
METLU737_05050(shc)
MPADKEF85_15850(shc)
MELLIVG45_06140(shc) IVG45_22120(shc)
MAHMEALZ_2523(shc) MEALZ_3097(shc)
MBUREQU24_14525(shc) EQU24_15370(shc)
MPSYCEK71_04645(shc) CEK71_11190(shc)
MMAIsS8_2362
MMOBF6R98_20825(shc)
MEINmethR_P0253
MOZMoryE10_13350(shc)
MISZMishRS11D_16130(shc)
MESLKKZ03_12960(shc)
NOCNoc_1320
NHLNhal_1309
NWANwat_1202
NWRE3U44_16810(shc)
NTTTAO_1298
TSYTHSYN_14920
NTGNSCAC_0561(shc)
ACIIC4901_05415(shc)
ATYA9R16_011075(shc)
SALNSALB1_2148
RPJN234_32520
REHH16_B2207(sqhC)
CNCCNE_2c21850(shc)
CUHBJN34_33525
REUReut_B4954
RMERmet_4148(sqhC) Rmet_4403(shc)
CTIRALTA_B1983(shc)
CBWRR42_s1630 RR42_s2399
CGDCR3_3463(shc)
CCUPBKK81_10785 BKK81_26340
CUPBKK80_11040 BKK80_29975
CUUBKK79_01795 BKK79_20625
CPAUEHF44_18565(shc) EHF44_19255(shc)
COXE0W60_04545(shc)
BMABMAA2100(shc)
BMVBMASAVP1_1129(shc)
BMLBMA10229_1408(shc)
BMNBMA10247_A2394(shc)
BMALDM55_3714(shc)
BMAEDM78_4588(shc)
BMAQDM76_4409(shc)
BMAIDM57_14635
BMAFDM51_3764(shc)
BMAZBM44_3673(shc)
BMABBM45_4450(shc)
BPSBPSS2339(shc)
BPMBURPS1710b_A1490(shc)
BPLBURPS1106A_A3161(shc)
BPDBURPS668_A3275(shc)
BPSEBDL_5818(shc)
BPSMBBQ_3760(shc)
BPSUBBN_5840(shc)
BPSDBBX_4987(shc)
BPZBP1026B_II2520(shc)
BPQBPC006_II3107
BPKBBK_5125(shc)
BPSHDR55_5386(shc)
BPSABBU_3646(shc)
BPSOX996_5156(shc)
BUTX994_4705(shc)
BTEBTH_II2359(shc)
BTQBTQ_3274(shc)
BTJBTJ_4306(shc)
BTZBTL_5108(shc)
BTDBTI_4772(shc)
BTVBTHA_5108(shc)
BTHEBTN_4769(shc)
BTHMBTRA_5036(shc)
BTHADR62_4873
BTHLBG87_5103(shc)
BOKDM82_3978(shc)
BOCBG90_4049(shc)
BUUWS70_28725
BSAVWS86_18650
BVIBcep1808_3808
BVEAK36_4901(shc)
BURBcep18194_B0019 Bcep18194_C7519
BCNBcen_5180 Bcen_5698
BCHBcen2424_5679 Bcen2424_6062
BCMBcenmc03_4556 Bcenmc03_6546
BCJBCAM2831(shc) BCAS0167(shc)
BCENDM39_5013(shc) DM39_6527(shc)
BCEWDM40_3396(shc)
BCEOI35_6711(shc) I35_7176(shc)
BAMBamb_4951 Bamb_6104
BACBamMC406_5504 BamMC406_5865
BMJBMULJ_05535(sqhC)
BMUBmul_3175 Bmul_5992
BMKDM80_4553(shc) DM80_6441(shc)
BMULNP80_3379(shc)
BCTGEM_5581
BCEDDM42_5157(shc) DM42_6654(shc)
BCEPAPZ15_24775 APZ15_33895
BDLAK34_4974(shc)
BPYRABD05_21485 ABD05_34000
BCONNL30_18005 NL30_34350
BUBBW23_4001(shc) BW23_5528(shc)
BDFWI26_26715 WI26_29610
BLATWK25_29560
BTEIWS51_10745 WS51_29420
BSEMWJ12_19620 WJ12_34020
BPSLWS57_00085 WS57_17555
BMECWJ16_19345 WJ16_32495
BSTGWT74_28725 WT74_32860
BSTLBBJ41_27930 BBJ41_33625
BANNJFN94_18175(shc)
BGLbglu_2g02870 bglu_2g22720
BGUKS03_3364(shc) KS03_3646(shc)
BUGBC1001_4759
BGFBC1003_4523
BGDbgla_2g03260 bgla_2g29870
BGOBM43_6721(shc) BM43_7081(shc)
BYIBYI23_B013720
BUKMYA_3465
BUEBRPE67_BCDS00680
BULBW21_4301(shc)
BUQAC233_26250
BGPBGL_2c02630 BGL_2c29490
BPLAbpln_2g03050 bpln_2g29530
BUDAQ610_31635
BUMAXG89_19290
BUIAX768_29055
BURKDM992_25920(shc) DM992_34725(shc)
BXEBxe_B0012
BXBDR64_5376(shc)
BPHBphy_4137
BGEBC1002_5086
BPXBUPH_01324
BPYBphyt_7029
BUZAYM40_35475
BFNOI25_5474(shc)
BCAIK788_0000709
PSPWBJG93_21555(shc)
PARABTO02_22395
PARBCJU94_28535(shc)
PHSC2L64_18375(shc)
PTERC2L65_16210(shc)
PGPCUJ91_29990(shc)
PCJCUJ87_28080(shc)
PTSCUJ90_23645(shc)
PCAFDSC91_003033
PMEGFNZ07_04850(shc)
PTROG5S35_20780(shc) G5S35_32265(shc)
PGISI6I06_28030(shc)
PACPFAZ97_21335(shc) FAZ97_23545(shc)
PACSFAZ98_17480(shc) FAZ98_18980(shc)
PEWKZJ38_24040(shc)
PDIOPDMSB3_3365.1(shc)
BRHRBRH_03441
PPNODA70_09090
PPNMLV28_21715
PRBX636_17400
PPULRO07_16105
PSPUNA29_21045
PAPISG18_24805
PVEUC34_07360
POXMB84_11695
PTXABW99_02790
PFGAB870_18055
PNRAT302_26700
PANDDRB87_06625(shc)
PFIBPI93_020480(shc)
CABASBC2_70700(shc)
BUOBRPE64_BCDS00810
VCVGJV44_p00024
BBAGE1O_05330
NEUNE1168
NETNeut_1507
NITNAL212_0906
NIINit79A3_1066
NCOAAW31_03760
NURATY38_01960
NSTNstercoris_01634
NMUNmul_A2556
NLCEBAPG3_003585(shc)
GSUGSU0688(shc-1) GSU3061(shc-2)
GSKKN400_0662(shc-1) KN400_3000(shc-2)
GMEGmet_0419(shc-2) Gmet_2820(shc-1)
GEMGM21_0885 GM21_2435
GEBGM18_3439
GPIGPICK_04085
GAOA2G06_14395
GEFFO488_03610(shc)
GBZJZM60_01925(shc) JZM60_07780(shc)
GURGura_1020
GEOGeob_3234(shc-2) Geob_3662(shc-1)
GLOGlov_2233
GBMGbem_1815 Gbem_3360(shc)
GBNGEOBRER4_08490(shc-1)
GERKP004_03725(shc)
GSUBKP001_11685(shc)
GNTKP003_03545(shc)
GPLM1B72_17015(shc)
PCAPcar_0355(shc-1) Pcar_0441(shc-2)
PACEA6070_01815
PPDPpro_0765 Ppro_1189
DSADesal_1353
DHYDESAM_22870(shc)
DAFDesaf_0189
DALDalk_0344
AFWAnae109_4079
AGEAA314_01781 AA314_05090 AA314_06818
CFUSCYFUS_004654
CCROCMC5_070180
PAUUE8A73_035210
MRMA7982_05934 A7982_06057
DAODesac_0410
SFUSfum_1989 Sfum_2736
BBAEFRD01_14570
PMOBHG718_04905(shc)
KMNHW532_17945(shc)
RHINGR_a00460(shc)
SINOSS05631_a45190
ESJSJ05684_a40290
BJAblr3004(shc)
BJUBJ6T_67630
BJPRN69_32800
BRABRADO6252(shc)
BBTBBta_1355(shc)
BRSS23_49930(shc)
AOLS58_64230
BRCBCCGELA001_13475
BRADBF49_1688
BICLMTR13_28330
BROBRAD285_6198(shc)
BRKCWS35_18225(shc)
BOTCIT37_38575(shc)
BRQCIT40_09520(shc)
BGQX265_25980(shc)
BGZXH91_24120(shc)
BSYMCIT39_08640(shc)
BBETF8237_05025(shc)
BARHWN72_16450(shc)
BVZBRAD3257_5706(shc)
BELBE61_70440(shc)
BDGLPJ38_18020(shc)
BSEPHAP48_0030900(shc)
BQBJ4P68_0032160(shc)
RPARPA3740(sqhC)
RPBRPB_1726
RPCRPC_1720
RPDRPD_3573
RPERPE_4468
RPTRpal_4261
RPXRpdx1_1605
RBKE0H22_09840(shc)
NWINwi_2269
NHANham_2682
OCAOCAR_6671(shc)
OCGOCA5_c13970(shc)
OCOOCA4_c13970(shc)
VGOGJW-30_1_02142(shc)
TRBHB776_13755(shc)
STARG3545_15480(shc)
MEAMex_1p1818(shc)
MDIMETDI2705(shc)
MEXMext_1944
MCHMchl_2220 Mchl_5491
MPOMpop_1835
MZAB2G69_17180
MRDMrad2831_5426
METM446_6347
MNOMnod_7146
MORMOC_3575(shc) MOC_6001
METAY590_09040
MAQUMaq22A_c25255(sqhC)
MPHYMCBMB27_04727 MCBMB27_05561
MEEDA075_06145(shc)
METDC0214_10795(shc)
METXA3862_03545 A3862_04290
METSDK389_19255(shc)
METIDK427_24635(shc)
MMESMMSR116_24425(shc)
MTEADK419_24980(shc)
MINDmvi_34500(shc_1) mvi_55610(shc_2)
MOGMMB17_13750(shc)
BIDBind_3156
MSLMsil_3243
MTUNMTUNDRAET4_2106
MLGCWB41_01845(shc)
BBARRHAL1_00135(shc)
HDNHden_0477
HDTHYPDE_24888
HMCHYPMC_3771(shc)
RVARvan_3017
RHZRHPLAN_23310
MSCBN69_1707
MROSEHO51_00730(shc)
MHEYH2LOC_015870(shc)
MPARF7D14_11010(shc)
MTWCQW49_17110(shc)
PSINCAK95_04485
TSOIZ6_27190(shc)
RBMTEF_04810
LIZLGH83_05690(shc) LGH83_16590(shc)
CAULKCG34_08815(shc)
ZMOZMO0872 ZMO1548
ZMNZa10_0420 Za10_1658
ZMMZmob_0425 Zmob_1582
ZMBZZ6_0423 ZZ6_1551
ZMIZCP4_0439 ZCP4_1608
ZMCA265_00434 A265_01607
ZMRA254_00434 A254_01607
ZMPZymop_0393
NORFA702_05035(shc)
SPHMG432_09180
SPANAWL63_21320
SPHAD3Y57_13895(shc)
POQKZX46_17575(shc)
GOXGOX2260
GOHB932_1860 B932_2742
GOYGLS_c24030
GALA0U94_06170
GTIFXF46_02260(shc) FXF46_13825(shc)
GSPIGS75_12765(shc)
GFAMKW11_02670(shc) MKW11_14255(shc)
GBEGbCGDNIH1_2107
GBHGbCGDNIH2_2107
GBCGbCGDNIH3_2107
GBSGbCGDNIH4_2107
ACRAcry_1685
AMVACMV_17290(shc)
GDIGDI1620
GDJGdia_1825
GXYGLX_03980
GXLH845_2357
KNAB0W47_03475
KEUS101446_01652 S101446_02249
KSCCD178_01159(shc)
KREGWK63_07055(shc)
APTAPA01_01950 APA01_13100
APWAPA42C_01950 APA42C_13100
APFAPA03_01950 APA03_13100
APUAPA07_01950 APA07_13100
APGAPA12_01950 APA12_13100
APQAPA22_01950 APA22_13100
APXAPA26_01950 APA26_13100
APZAPA32_01950 APA32_13100
APKAPA386B_146(shc) APA386B_1683(shc)
ASZASN_2208(shc)
ASVWG31_01015 WG31_07060
AACEA0U92_11670
APERA0U91_06975
APOMCPF11_00890(shc) CPF11_06325(shc)
ATOCIW82_01590(shc)
AASCA4S02_04580 A4S02_11565
ACETDS739_01115(shc) DS739_06780(shc)
AOTAcetOri_orf02407
AOYEOV40_001040(shc) EOV40_006100(shc)
ACEKFLP30_07000(shc)
ABGAsbog_02594
KBAA0U89_01840
RGIRGI145_09730
ROSCTJ15_07690(shc)
RMUCFOB66_09715(shc)
RMTIAI58_18595(shc)
NCHA0U93_11945
COQD9V35_08220(shc)
COMMGN303_08020(shc)
NTND5366_10600(shc)
NEHE3E11_07665(shc)
SSAME3D00_09665(shc)
SWFE3E12_06930(shc)
BOBGN304_03820(shc)
BOMBGT348_03345(shc)
EBLAJGUZn3_04090(shc)
LCKHN018_00140(shc)
KHAIFJ82_01385(shc) IFJ82_02850(shc)
PARZDTQ13_08075(shc)
SRFLHU95_12750(shc)
RAPRHOA_2339(shc)
SHUMSTHU_32380(shc)
SVCSTVA_26800(shc)
ABSAZOBR_p150003(shc)
ABQABAZ39_20220
ABFAMK58_14585
AZTTSH58p_24395(shc)
NAOY958_22670(shc)
SKTIGS68_20550(shc)
SMUCJL100_005555(shc)
SROEJL101_005465(shc)
RRURru_A0062
RRFF11_00315
RPMRSPPHO_00431
MAGamb1367
MAGXXM1_1990(shc)
MAGNWV31_17685
HTQFRZ44_04170
HADHFRZ61_04440
DEXHWD60_12235(shc)
DVNHQ394_07730(shc)
MAGQMGMAQ_1494(shc)
AFRAFE_2124(shc)
AFELferr_1783
ACUAtc_2240
ACZAcaty_c2080
AFIAcife_1270
AFJAFERRID_02580
ATXGCD22_00868(shc)
AFPK1Y48_00780(shc)
AACAaci_2443
AADTC41_2733(shc)
AACOK1I37_18755(shc)
RHEREHE19_016535
AACXDEACI_3142
EUUADJ67_00305
NNONONO_c55610
NTPCRH09_14130 CRH09_23905(shc) CRH09_26605
NAHF5544_21420
NWLNWFMUON74_15100
NHUH0264_16265
SCOSCO6764(SC6A5.13)
SALBXNR_0267
SMASAVERM_1650(hopA)
SGRSGR_962(hopA)
SGBWQO_30780
SCBSCAB_12951(hopA)
SSXSACTE_5926
SVLStrvi_2867 Strvi_5132
SHYSHJG_7654
SHOSHJGH_7415
SRCM271_11170
SMALSMALA_0221 SMALA_6345
SSOII1A49_35575(shc)
SCTSCAT_4943(shc) SCAT_5607
SCYSCATT_49380 SCATT_56060
SFASfla_0644
SBHSBI_00220 SBI_02586(hopA)
SVESVEN_6451
SDVBN159_1597(shc)
SALSSLNWT_6814
STRPF750_6225
SFISFUL_6533
SCIB446_30850
SALUDC74_6782 DC74_7525
SALLSAZ_35230 SAZ_38855
SLVSLIV_04695(shc)
SGUSGLAU_28290
SVTSVTN_31635
STREGZL_01982
SCWTU94_29090
SLDT261_1203
SLCSL103_23610
SXISXIM_51340
STRMM444_28180
STRCAA958_32215
SAMBSAM23877_6414(shc)
SPRISPRI_0982
SCZABE83_03660 ABE83_33310
SCXAS200_08990 AS200_35430
SRWTUE45_00448 TUE45_07304(shc)
STRFASR50_30475
SLEsle_10520(sle_10520)
SRNA4G23_05042(shc)
SPAVSpa2297_28170
STRTA8713_27345 A8713_30300
SCLFBB341_00560 BB341_02805
SGSAVL59_15150
STSIA4E84_34770
SKYD0C37_02860(shc)
SALWCP975_31255(shc)
SGMGCM10017557_11400
SCADDN051_08510(shc)
SLSSLINC_6334 SLINC_7200
SNRSNOUR_08855
SPLULK06_028610
STRDNI25_04620
SNWBBN63_05555
SAUOBV401_04845 BV401_35705
SSIAA7J05_05110
SVUB1H20_31600
SPUNBFF78_06420
SGVB1H19_34415 B1H19_35795
SLAUSLA_6410
SALFSMD44_07318(shc)
SALJSMD11_1098(shc)
SLXSLAV_07390(shc)
STROSTRMOE7_31880
SFKKY5_7137
SNZDC008_29665(shc)
SGEDWG14_01401(shc)
SRJSRO_1200
SLKSLUN_34175(shc)
SDXC4B68_04810(shc)
SGDELQ87_05325(shc)
SQZFQU76_00220 FQU76_29310(shc) FQU76_33520
SCYAEJ357_40565(shc)
SASTCD934_03265(shc)
SNQCP978_28955(shc)
STIRDDW44_27260(shc)
SKACP970_04385(shc)
SGZC0216_10745(shc)
SVNCP980_05860(shc)
SNKCP967_02225(shc)
SRKFGW37_27085(shc) FGW37_31230 FGW37_32255
SFICEIZ62_04350(shc)
SGALCP966_00565 CP966_31125(shc)
SSPODDQ41_28530(shc)
SVRCP971_05135(shc)
SPADDVK44_19855 DVK44_30855(shc)
SFYGFH48_08095(shc)
SAQUEJC51_39490(shc)
SGFHEP81_01168(shc)
SCAVCVT27_30035(shc)
SSEOD0Z67_24820(shc)
SBYH7H31_30105(shc)
SRIMCP984_05710(shc) CP984_38180(shc)
SSUBCP968_06340(shc)
SPHVF9278_40805(shc)
SCINCP977_10960 CP977_28910(shc)
SFUGCNQ36_31010(shc)
SPACB1H29_05430
STSUB7R87_29445
SCHACP983_06415(shc)
SGXH4W23_32745(shc)
SCOECP976_37120(shc)
SBATG4Z16_03480(shc)
SSPBCP982_34195(shc)
SNFJYK04_06893(shc)
SPLACP981_01965 CP981_32445(shc)
SBROGQF42_07575 GQF42_37630(shc)
STUIGCM10017668_61190
SATAC5746_35860(shc)
SCHFIPT68_31720(shc)
SHUNDWB77_01404(shc)
SHARHUT13_25935
SCYGS1361_33295(shc)
SFEUIM697_28460(shc)
SLIAHA039_04290(shc)
SDWK7C20_01965 K7C20_30995(shc)
SVDCP969_32315(shc)
SCALI6J39_31405(shc)
SAUHSU9_029415(shc)
SFBCP974_26940(shc)
SMOBJ7W19_04550 J7W19_27235(shc) J7W19_27655
SPEUCGZ69_31900(shc)
SROIIAG44_38275
SXNIAG42_05315(shc)
SGJIAG43_28430(shc)
SHKJ2N69_32850(shc)
SANUK7396_06215(shc)
STRYEQG64_31380(shc)
SACTDMT42_32475(shc)
SMAOCAG99_06465 CAG99_26915
SGOBtest1122_24235(shc)
SINEKI385_36760(shc)
SLFJEQ17_08695(shc)
SDECL3078_39030(shc)
KSKKSE_17590
KABB7C62_21470 B7C62_32710
KAUB6264_00545
KITCFP65_0190 CFP65_6584
YIALO772_08835(shc) LO772_31665
ALXLVQ62_17075(shc)
ACTWF7P10_06045(shc)
AGRAAGRA3207_001324(shc)
NOWGBF35_34755(shc)
NCXNocox_41615(shc)
FRAFrancci3_0823
FREFranean1_4758 Franean1_5713
FRIFraEuI1c_2682 FraEuI1c_5917
FALFRAAL1432(shc1) FRAAL2491(shc2)
FSYFsymDg_1170
ACEAcel_1697
BSDBLASA_0211(shc)
SENSACE_4327(shc1) SACE_4648
SACGFDZ84_19500 FDZ84_33290(shc) FDZ84_37270
SVISvir_23080
SACCEYD13_11020(shc1) EYD13_12855(shc2)
AMQAMETH_4077(shc1)
AMYCCU254_13920(shc)
AMYYYIM_15135(shc)
AACDLWP59_21025(shc)
PDXPsed_3680
PSEHXF36_18915
PHHAFB00_04195 AFB00_16765
APRECNX65_21970
AMIAmir_4385
SSYIEKG83_15250 EKG83_31035
KALKALB_4044
ACTIUA75_12830
ACADUA74_12750
AHGAHOG_12025(shc)
ALOCRK61965
PMADBAY61_14060
MAUMicau_3713
MILML5_4686
MICBMicB006_2812
MICHFJK98_09315
PLABC6361_04775(shc)
PLATC6W10_01300(shc)
PFLAPflav_027740
PSUUPsuf_090700
ATLAthai_51160
ASERAsera_23680
PRYPrubr_63970
CAICaci_6664
AEYCDG81_09445(shc)
RXYRxyl_2756
BSOLFSW04_24315(shc)
SYNslr2089(shc)
SYZMYO_114140(shc)
SYYSYNGTS_1402(shc)
SYTSYNGTI_1402(shc)
SYSSYNPCCN_1401(shc)
SYQSYNPCCP_1401(shc)
SYJD082_00070(shc)
SYOC7I86_07260(shc)
SYNESyn6312_1461
SYNPSyn7502_03476
AMRAM1_4845(shc)
TVNNIES2134_122340(shc)
SLWBRW62_00510
TELtlr2309(shc)
THNNK55_08140(sqhC)
THECFFX45_04995(shc)
LENLEP3755_00050
LBOLBWT_51590
KOVK9N68_23475(shc)
LSCKIK02_09045(shc)
LSKJ5X98_02115(shc)
HHGXM38_041670(shc)
GENGM3709_1659
GEEGM3708_231
MARMAE_44950(shc)
MPKVL20_2504
MIQB5D77_03340
MVZmyaer102_18990(shc)
CANCyan10605_1649
CYUUCYN_09140
CYTcce_4510(shc)
CWACwatDRAFT_6219
CYPPCC8801_2842
CYHCyan8802_3254
CYCPCC7424_3320
CYJCyan7822_0123
CYNCyan7425_3575
TERTery_0727
PAGHNIES204_29660
MICMic7113_5949
MPROBJP34_24710
PHORJWS08_00180(shc)
GVIglr4057(shc)
GLJGKIL_2413(shc)
GMLISF26_20930(shc)
ANAall0775
NPUNpun_R6245
NOSNos7107_0414
NOPNos7524_3073 Nos7524_5159
NONNOS3756_03280
NFLCOO91_07277
NOECLI64_14195(shc)
NSHGXM_01577
NEDHUN01_06045(shc)
AVAAva_4671
ANBANA_C12765
ACYAnacy_5203
AWAAA650_12920
ANNEH233_26715(shc)
CSGCylst_2445
RSINB6N60_02202
CALOCal7507_0308
CALTCal6303_3753
FISFIS3754_26860
DOUBMF77_04608(shc)
DFSHGD76_07565(shc)
CCURIAR63_14650(shc)
AFLOHEQ12_11025(shc)
TOQHCG51_07545(shc)
NCNBZZ01_14710
PLPPle7327_2716
SCSSta7437_3936
STANSTA3757_10830
CEOETSB_1175(shc)
CERRGRSB_1837(shc)
STISthe_2007
KBSEPA93_16020(shc) EPA93_17550 EPA93_17590
CCZCCALI_00139 CCALI_01615
RUFIK0V07_00965(shc)
AMUAmuc_0525
ROOG5S37_27275
MINMinf_0399(sqhC)
MKCkam1_559
MEAPMTHMO_0319(sqhC)
RBARB11156 RB2901 RB2998 RB5934(shc)
PSLPsta_0174 Psta_0945 Psta_1738
PIRVN12_10680
RULUC8_30240 UC8_37370 UC8_42670(sqhC)
RMLFF011L_18080(sqhC) FF011L_23770 FF011L_27960
MFFMFFC18_41350(sqhC) MFFC18_46730
ROLCA51_14560 CA51_39620 CA51_52070(shc)
AHELQ31a_22040(shc_1) Q31a_45820 Q31a_46410(shc_2)
LCREPla8534_14350 Pla8534_20930(sqhC) Pla8534_22350(shc)
AAGGETAA8_10120 ETAA8_62290(shc_1) ETAA8_62430(shc_2)
BVOPan97_09230(shc_1) Pan97_09420(shc_2)
RLCK227x_13510 K227x_22910(shc) K227x_33480 K227x_40600
TTFTHTE_1935 THTE_2306 THTE_3916
AMUCPan181_46940
PNDPla175_18410(shc)
AMOBHG15A2_00430 HG15A2_44900(shc)
PLMPlim_0903 Plim_1904 Plim_4048
PEHSpb1_06060 Spb1_15260(shc_1) Spb1_27280(shc_2)
PBSPlabr_0011 Plabr_2149 Plabr_2180
PLSVT03_01505 VT03_09805 VT03_26490(shc_2) VT03_32785(shc_3)
PLHVT85_07400 VT85_20580(shc)
FMRFuma_03128(shc) Fuma_03348 Fuma_03645
GMRGmarT_15340 GmarT_24340(shc_1) GmarT_47090(shc_2) GmarT_54430
GIMF1728_02355 F1728_17190 F1728_21675
GPNPan110_23630(shc_1) Pan110_45560(shc_2)
MRIMal4_31980(shc) Mal4_50450(sqhC)
SDYNMal52_02110 Mal52_19580(shc) Mal52_49180(sqhC)
PLONPla110_32440(shc_1) Pla110_36000(shc_2)
GESVT84_13505(shc_1) VT84_20280(shc_2) VT84_26700 VT84_29250 VT84_38410
GOGC1280_00600 C1280_05755 C1280_11220 C1280_15490 C1280_24955
GMSSOIL9_23180 SOIL9_23870
TIMGMBLW1_02660 GMBLW1_14470 GMBLW1_45200
LRSPX52LOC_02174(shc) PX52LOC_03438
FTJFTUN_0199 FTUN_6577 FTUN_6629
ULIETAA1_06450(sqhC) ETAA1_31320(shc)
TSPHKIH39_00860
IPAIsop_2195 Isop_2285
SACISinac_2971 Sinac_7098 Sinac_7166
PBORBSF38_01778 BSF38_02668 BSF38_04488(shc)
AGVOJF2_06420 OJF2_33050 OJF2_48380(shc)
KSTKSMBR1_2174
BROCIPI25_11045(shc)
BPITBPIT_03260
JETL3J17_11495(shc)
PHMPSMK_10120
PCORKS4_02460(shc)
MCADPan265_12120(shc)
HBSIPV69_04890(shc) IPV69_19905
UAMUABAM_04164 UABAM_06659
ABAAcid345_1740
ACAACP_3329(shc)
ACMAciX9_1592
GMAAciX8_1346
GRWFTO74_09370(shc)
TSAAciPR4_1994
TRSTerro_1976 Terro_2342
TALBFTW19_15285(shc) FTW19_25255(shc)
ABASACPOL_1272
EDAGWR55_04250(shc)
ADINH7849_03035(shc) H7849_09985
SUSAcid_1186 Acid_1260 Acid_3957
PFERIRI77_14385(shc) IRI77_19010(shc) IRI77_21610
CTMCabther_B0033
CVLJ8C06_11290(shc)
CHLOJ8C02_11955(shc)
ABACLuPra_04105
SCORJ3U87_05010 J3U87_08330
GBAJ421_6268
MBASALGA_3836
CHITFW415_14435
FLNFLA_1944
FSDLXD69_15565
MAREEJ994_14175
NDENIDE0861(shc)
NMVNITMOv2_0719(shc)
NIONITINOP_1569(shc)
NJANSJP_1836(shc)
NKFNkreftii_003246
LFCLFE_1762
LFILFML04_0857
LFPY981_03765
LEGABH19_09330
NLIG3M70_08320(shc)
BANABARAN1_1143(shc)
BIHBIP78_1402
MOXDAMO_0045(shc)
HALJG9465_03285
IHOIgni_0441
 » show all
Reference
1  [PMID:12120044]
  Authors
Hoshino T, Sato T.
  Title
Squalene-hopene cyclase: catalytic mechanism and substrate recognition.
  Journal
10.1039/b108995c
Reference
2  [PMID:15136801]
  Authors
Hoshino T, Nakano S, Kondo T, Sato T, Miyoshi A
  Title
Squalene-hopene cyclase: final deprotonation reaction, conformational analysis for the cyclization of (3R,S)-2,3-oxidosqualene and further evidence for the requirement of an isopropylidene moiety both for initiation of the polycyclization cascade and for the formation of the 5-membered E-ring.
  Journal
Org Biomol Chem 2:1456-70 (2004)
DOI:10.1039/b401172d
Reference
3  [PMID:15056909]
  Authors
Sato T, Kouda M, Hoshino T
  Title
Site-directed mutagenesis experiments on the putative deprotonation site of squalene-hopene cyclase from Alicyclobacillus acidocaldarius.
  Journal
Biosci Biotechnol Biochem 68:728-38 (2004)
DOI:10.1271/bbb.68.728
Reference
4  [PMID:15113001]
  Authors
Reinert DJ, Balliano G, Schulz GE
  Title
Conversion of squalene to the pentacarbocyclic hopene.
  Journal
Chem Biol 11:121-6 (2004)
DOI:10.1016/j.chembiol.2003.12.013
Other DBs
ExplorEnz - The Enzyme Database: 5.4.99.17
IUBMB Enzyme Nomenclature: 5.4.99.17
ExPASy - ENZYME nomenclature database: 5.4.99.17
BRENDA, the Enzyme Database: 5.4.99.17
CAS: 76600-69-6

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