KEGG   ENZYME: 5.4.99.3
Entry
EC 5.4.99.3                 Enzyme                                 
Name
2-acetolactate mutase;
acetolactate mutase;
acetohydroxy acid isomerase
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
Sysname
2-acetolactate methylmutase
Reaction(IUBMB)
2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate [RN:R03052]
Reaction(KEGG)
R03052 > R05071;
(other) R05069
Substrate
2-acetolactate [CPD:C00900]
Product
3-hydroxy-3-methyl-2-oxobutanoate [CPD:C04181]
Comment
Requires ascorbic acid; also converts 2-aceto-2-hydroxybutanoate to 3-hydroxy-3-methyl-2-oxopentanoate.
History
EC 5.4.99.3 created 1972
Pathway
ec00290  Valine, leucine and isoleucine biosynthesis
ec01110  Biosynthesis of secondary metabolites
Reference
1  [PMID:4384955]
  Authors
Allaudeen HS, Ramakrishnan T.
  Title
Biosynthesis of isoleucine and valine in Mycobacterium tuberculosis H37 Rv.
  Journal
Arch Biochem Biophys 125:199-209 (1968)
DOI:10.1016/0003-9861(68)90655-3
Other DBs
ExplorEnz - The Enzyme Database: 5.4.99.3
IUBMB Enzyme Nomenclature: 5.4.99.3
ExPASy - ENZYME nomenclature database: 5.4.99.3
BRENDA, the Enzyme Database: 5.4.99.3
CAS: 37318-52-8

  All links  
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (5)   
   KEGG REACTION (3)   
   KEGG RCLASS (2)   
All databases (14)   

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