KEGG   ENZYME: 5.4.99.48Help
Entry
EC 5.4.99.48                Enzyme                                 

Name
achilleol B synthase
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
BRITE hierarchy
Sysname
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, achilleol-B-forming)
Reaction(IUBMB)
(3S)-2,3-epoxy-2,3-dihydrosqualene = achilleol B [RN:R09908]
Reaction(KEGG)
Substrate
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:C01054]
Product
achilleol B [CPD:C20187]
Comment
Achilleol B is probably formed by cleavage of the 8-14 and 9-10 bonds of (3S)-2,3-epoxy-2,3-dihydrosqualene as part of the cyclization reaction, after formation of the oleanane skeleton.
History
EC 5.4.99.48 created 2011
Pathway
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K19011  achilleol B synthase
Genes
OSA: 4350288
DOSA: Os11t0285000-01(Os11g0285000)
OBR: 102703694
BDI: 100827654
SBI: 8063842 8073228
ZMA: 103626416 103654534
SITA: 101767046 101784323
Taxonomy
Reference
1  [PMID:21526825]
  Authors
Ito R, Mori K, Hashimoto I, Nakano C, Sato T, Hoshino T
  Title
Triterpene cyclases from Oryza sativa L.: cycloartenol, parkeol and achilleol B synthases.
  Journal
Org Lett 13:2678-81 (2011)
DOI:10.1021/ol200777d
  Sequence
[osa:4350288]
Other DBs
ExplorEnz - The Enzyme Database: 5.4.99.48
IUBMB Enzyme Nomenclature: 5.4.99.48
ExPASy - ENZYME nomenclature database: 5.4.99.48
BRENDA, the Enzyme Database: 5.4.99.48

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