KEGG   ENZYME: 5.4.99.8
Entry
EC 5.4.99.8                 Enzyme                                 
Name
cycloartenol synthase;
2,3-epoxysqualene cycloartenol-cyclase;
squalene-2,3-epoxide-cycloartenol cyclase;
2,3-epoxysqualene-cycloartenol cyclase;
2,3-oxidosqualene-cycloartenol cyclase;
(S)-2,3-epoxysqualene mutase (cyclizing, cycloartenol-forming)
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
Sysname
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, cycloartenol-forming)
Reaction(IUBMB)
(3S)-2,3-epoxy-2,3-dihydrosqualene = cycloartenol [RN:R03200]
Reaction(KEGG)
R03200
Substrate
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:C01054]
Product
cycloartenol [CPD:C01902]
History
EC 5.4.99.8 created 1972
Pathway
ec00100  Steroid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K01853  cycloartenol synthase
Genes
ATHAT2G07050(CAS1)
ALY9319823
CRB17892775
CSAT104699484 104747242 104766598
EUSEUTSA_v10002412mg EUTSA_v10003155mg
BRP103828738 103860345
BNA106357881 106389426 106390933 106439781 106452896 111213217
BOE106301642 106335940
RSZ108863261
THJ104815309
CPAP110807341 110811331 110811369
CIT102614438 102616606 102624399
CICCICLE_v10007530mg CICLE_v10007532mg CICLE_v100104161m CICLE_v10031300mg
PVY116113639 116122245
MINC123194145 123194708 123194709 123195062 123199591 123199601 123209409 123217357
TCC18592839 18595555
GRA105769786 105781103 105790143
GHI107906370 107926281 107938607 107958480 121220183
GAB108453516 108465255 108469941
DZI111280304 111301783 111303485
EGR104437296 104452901 104454600 104455957 104455962
GMX100784662 548054
GSJ114387566 114407088 114407117
PVUPHAVU_004G1782001 PHAVU_004G178300g PHAVU_010G013200g
VRA106756220 106770354 106774156
VAR108343827 108345659 108346678
VUN114166342 114166874 114181303 114182005
CCAJ109804013 109804016
APRC113850931 113867122 113867123
MTRMTR_5g008810 MTR_6g088140 MTR_6g093100 MTR_7g062020
CAM101490563 101513129 101513765
LJALj0g3v0064609.1(Lj0g3v0064609.1) Lj2g3v0914430.1(Lj2g3v0914430.1) Lj2g3v0914440.1(Lj2g3v0914440.1) Lj2g3v0914610.1(Lj2g3v0914610.1) Lj5g3v0196770.1(Lj5g3v0196770.1) Lj5g3v0196780.1(Lj5g3v0196780.1)
ADU107469351 107490125 107490126
AIP107622483 107641333 107644501
AHF112751365 112751366 112783770 112801995 112801996
LANG109358649
FVE101303328 101303612 101305280
RCN112181444 112188239 112197019 112198839 112200888 112200892 112200893 112203920
PPER18781706 18790596 18791718
PMUM103323709 103323710 103327458
PAVI110750884 110761668 110766192
PDUL117621167 117622045 117628265
MDM103404080 103411553 103416907 103453651
PXB103937092 103938459 103952204 103959405 103959409 103967648
ZJU107417571 107428102
MNT21391577 21391578 21398257
CSV101217431
CMO103500608
BHJ120085608
MCHA111009148
CMAX111494351
CMOS111464358
CPEP111778539
RCU8262543
HBR110639722 110663875
MESC110609400 110609720
POP112325920 18099961 18107876 7465579 7485522 7487228
PEU105120889 105122514 105122515 105130440
PALZ118029067 118042654 118050538 118053411 118053412 118053414
JRE108989509 108989528 109002864
QSU111985651 111985655
QLO115967271 115967287 115967925 115969279 115989776 115991778
TWL119990993 119993804 119997366 120004801 120013217
VVI100242755 100243389 100244476 100247898 100253021 100255370 100258153
VRI117922243 117922565 117922566 117922677 117925320
SLY100147715(CAS1) 101261713
SPEN107017821 107019931
SOT102581012 102594718 102602455
CANN107867693
NTA107762593(CAS1) 107791205 107806219 107818919 107826198
NSY104215565 104215915 104239260 104244319
NTO104110614 104112536
NAU109241809 109242372
INI109146818 109146832 109191683
ITR115999025 116013063 116013826 116013828 116013829
SIND105161989 105173846
OEU111366072 111372683 111372684
EGT105969968 105969969 105970930 105973538
SSPL121780628 121796205 121799954
HAN110878812 110886225
ECAD122589354 122595810
LSV111885047 111917974 111921551
CCAV112502198 112515286 112527330
DCR108199746 108216519 108218260 108218262
CSIN114271755 114275045 114289539 114323656
BVG104893142
SOE110795205
CQI110692780 110696535
NNU104588379 104589213 104607389
MING122073767
TSS122662654
PSOM113300013 113358759
NCOL116266808 116266810 116266844 116266870 116266876 116266909
OSA4328254 4328256
DOSAOs02t0139700-01(Os02g0139700)
OBR102707275
BDI100824616 100835163 100843077 100843581 100844079
ATS109751858 109764558 109769220 109771122 109771125 109772962 109785654
TDC119296771 119298740 119315166 119320747 119325416
TAES123101940 123106228 123119046 123124067 123124069 123132185 123136214 123136217 123143716 123143717 123143724
TUA125506826 125513501 125514950 125518243
SBI8062823 8071830
ZMA100382426 103634847 103654926
SITA101754363 101755344
SVS117850810 117862485 117867052
PVIR120645971 120646390 120654621 120654622
PHAI112879756
PDA103695874 103712248 103720893 103720906 103720908
EGU105033111 105049265 105049266 105049267 105053370
MUS103991762
DCT110101415
PEQ110039035
AOF109822125
ATR18440783
SMOSELMODRAFT_129950 SELMODRAFT_160256 SELMODRAFT_266790 SELMODRAFT_269539 SELMODRAFT_81943
PPP112295262
CRECHLRE_01g011100v5
VCNVOLCADRAFT_96220
CSLCOCSUDRAFT_54267
CVRCHLNCDRAFT_22200
APROF751_3159
OLUOSTLU_12302
OTAOT_ostta03g00880
BPGBathy06g02200
MISMICPUN_55325
MPPMICPUCDRAFT_24736
CMECYME_CMJ009C
GSLGasu_60260
CCPCHC_T00008265001
FCYFRACYDRAFT_209964
TPSTHAPSDRAFT_277(CAS1)
EHXEMIHUDRAFT_458646 EMIHUDRAFT_462848
MCGGL4_3110
 » show all
Reference
1  [PMID:5797101]
  Authors
Rees HH, Goad LJ, Goodwin TW.
  Title
2,3-oxidosqualene cycloartenol cyclase from Ochromonas malhamensis.
  Journal
Biochim Biophys Acta 176:892-4 (1969)
DOI:10.1016/0005-2760(69)90274-4
Other DBs
ExplorEnz - The Enzyme Database: 5.4.99.8
IUBMB Enzyme Nomenclature: 5.4.99.8
ExPASy - ENZYME nomenclature database: 5.4.99.8
BRENDA, the Enzyme Database: 5.4.99.8
CAS: 9075-25-6

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