Entry
Name
lycopene epsilon-cyclase;
CrtL-e;
LCYe;
carotenoid psi-end group lyase (decyclizing)
Class
Isomerases;
Intramolecular lyases;
Intramolecular lyases (only sub-subclass identified to date)
BRITE hierarchy
Sysname
carotenoid psi-end group lyase (ring-opening)
Reaction(IUBMB)
carotenoid psi-end group = carotenoid epsilon-end group
Reaction(KEGG)
Substrate
carotenoid psi-end group
Product
carotenoid epsilon-end group
Comment
The carotenoid lycopene has the psi-end group at both ends. When acting on one end, this enzyme forms delta-carotene. When acting on both ends, it forms epsilon-carotene.
History
EC 5.5.1.18 created 2011
Pathway
ec01110 Biosynthesis of secondary metabolites
Orthology
K06444 lycopene epsilon-cyclase
Genes
CSAT : 104733913 104761775 109124564
BNA : 106371493 106387316 106418464 106436514
RSZ : 108828178 108844261 130505650 130509272
GHI : 107907128 107932206 107937734 107944259
HSYR : 120131995 120166545 120209704
PMUM : 103340735 107880066
CMAX : 111465770 111493821
CMOS : 111444042 111450793
CPEP : 111799301 111805864
VRI : 117905657 117907400 117925618
NTA : 107789691(LYCe) 107830918
SSPL : 121748905 121752194 121806356
SHIS : 125189034 125197377
PSOM : 113294804 113318755
MFLO : 136450070 136456162 136456164
PVIR : 120673640 120707193
SMO : SELMODRAFT_101391 SELMODRAFT_132340
CVR : CHLNCDRAFT_19656(LCYE)
» show all
Taxonomy
Reference
Authors
Cunningham FX Jr, Gantt E
Title
One ring or two? Determination of ring number in carotenoids by lycopene epsilon-cyclases.
Journal
Sequence
Reference
Authors
Stickforth P, Steiger S, Hess WR, Sandmann G.
Title
A novel type of lycopene epsilon-cyclase in the marine cyanobacterium Prochlorococcus marinus MED4.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 5.5.1.18
ExPASy - ENZYME nomenclature database: 5.5.1.18