Entry |
|
Name |
acetoacetate---CoA ligase;
acetoacetyl-CoA synthetase
|
Class |
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
 |
Sysname |
acetoacetate:CoA ligase (AMP-forming)
|
Reaction(IUBMB) |
ATP + acetoacetate + CoA = AMP + diphosphate + acetoacetyl-CoA [RN: R01357]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
|
Comment |
Also acts, more slowly, on L-3-hydroxybutanoate.
|
History |
EC 6.2.1.16 created 1984
|
Pathway |
ec00280 | Valine, leucine and isoleucine degradation |
|
Orthology |
K01907 | acetoacetyl-CoA synthetase |
|
Genes |
» show all
 |
Reference |
|
Authors |
Fukui T, Ito M, Tomita K. |
Title |
Purification and characterization of acetoacetyl-CoA synthetase from Zoogloea ramigera I-16-M. |
Journal |
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Other DBs |
ExplorEnz - The Enzyme Database: | 6.2.1.16 |
ExPASy - ENZYME nomenclature database: | 6.2.1.16 |
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