| Entry |
|
|---|
| Name |
benzoate---CoA ligase;
benzoate---coenzyme A ligase;
benzoyl-coenzyme A synthetase;
benzoyl CoA synthetase (AMP forming)
|
|---|
| Class |
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
 |
|---|
| Sysname |
benzoate:CoA ligase (AMP-forming)
|
|---|
| Reaction(IUBMB) |
ATP + benzoate + CoA = AMP + diphosphate + benzoyl-CoA [RN: R01422]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
|
|---|
| Product |
|
|---|
| Comment |
Also acts on 2-, 3- and 4-fluorobenzoate, but only very slowly on the corresponding chlorobenzoates.
|
|---|
| History |
EC 6.2.1.25 created 1989
|
|---|
| Pathway |
| ec01120 | Microbial metabolism in diverse environments |
|
|---|
| Orthology |
| K04105 | 4-hydroxybenzoate-CoA ligase |
|
|---|
| Genes |
» show all
 |
|---|
| Reference |
1 |
|---|
| Authors |
Hutber, G.N. and Ribbons, D.W. |
|---|
| Title |
Involvement of coenzyme-A esters in the metabolism of benzoate and cyclohexanecarboxylate by Rhodopseudomonas palustris. |
|---|
| Journal |
J Gen Microbiol 129:2413-2420 (1983) |
|---|
| Reference |
|
|---|
| Authors |
Schennen U, Braun K, Knackmuss HJ. |
|---|
| Title |
Anaerobic degradation of 2-fluorobenzoate by benzoate-degrading, denitrifying bacteria. |
|---|
| Journal |
|
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 6.2.1.25 |
| ExPASy - ENZYME nomenclature database: | 6.2.1.25 |
| UM-BBD (Biocatalysis/Biodegradation Database): | 6.2.1.25 |
|
|---|
