Entry |
|
Name |
benzoate---CoA ligase;
benzoate---coenzyme A ligase;
benzoyl-coenzyme A synthetase;
benzoyl CoA synthetase (AMP forming)
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Class |
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
 |
Sysname |
benzoate:CoA ligase (AMP-forming)
|
Reaction(IUBMB) |
ATP + benzoate + CoA = AMP + diphosphate + benzoyl-CoA [RN: R01422]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
Also acts on 2-, 3- and 4-fluorobenzoate, but only very slowly on the corresponding chlorobenzoates.
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History |
EC 6.2.1.25 created 1989
|
Pathway |
ec01120 | Microbial metabolism in diverse environments |
|
Orthology |
K04105 | 4-hydroxybenzoate-CoA ligase |
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Genes |
» show all
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Reference |
1 |
Authors |
Hutber, G.N. and Ribbons, D.W. |
Title |
Involvement of coenzyme-A esters in the metabolism of benzoate and cyclohexanecarboxylate by Rhodopseudomonas palustris. |
Journal |
J Gen Microbiol 129:2413-2420 (1983) |
Reference |
|
Authors |
Schennen U, Braun K, Knackmuss HJ. |
Title |
Anaerobic degradation of 2-fluorobenzoate by benzoate-degrading, denitrifying bacteria. |
Journal |
J Bacteriol 161:321-5 (1985) |
Other DBs |
ExplorEnz - The Enzyme Database: | 6.2.1.25 |
ExPASy - ENZYME nomenclature database: | 6.2.1.25 |
UM-BBD (Biocatalysis/Biodegradation Database): | 6.2.1.25 |
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