KEGG   ENZYME: 6.2.1.27
Entry
EC 6.2.1.27                 Enzyme                                 
Name
4-hydroxybenzoate---CoA ligase;
4-hydroxybenzoate-CoA synthetase;
4-hydroxybenzoate---coenzyme A ligase (AMP-forming);
4-hydroxybenzoyl coenzyme A synthetase;
4-hydroxybenzoyl-CoA ligase
Class
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
Sysname
4-hydroxybenzoate:CoA ligase (AMP-forming)
Reaction(IUBMB)
ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA [RN:R01300]
Reaction(KEGG)
R01300
Substrate
ATP [CPD:C00002];
4-hydroxybenzoate [CPD:C00156];
CoA [CPD:C00010]
Product
AMP [CPD:C00020];
diphosphate [CPD:C00013];
4-hydroxybenzoyl-CoA [CPD:C02949]
History
EC 6.2.1.27 created 1992
Pathway
ec00362  Benzoate degradation
ec00627  Aminobenzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K04105  4-hydroxybenzoate-CoA ligase
K20458  3-hydroxybenzoate/4-hydroxybenzoate---CoA ligase
Genes
MTHDA3224_01560
MIIBTJ40_01805
ADIB5T_02169
CRZD1345_21875
CHAECH06BL_45340
PBHAAW51_0206(badA)
EBAebA727(hbcL)
ABREpbN1_30670(hbcL)
APETToN1_26910(hbcL)
AZIAzCIB_4612
AZDCDA09_22605
TCLTchl_2972
TAKTharo_1872
DDZDSYM_23670
SURSTAUR_3224
MESOBSQ44_18050
RPODE0E05_11160
NIYFQ775_02940
KMNHW532_10710
ABAWD5400_06445
BJAblr1077(blr1077)
BJUBJ6T_11070
BJPRN69_05405
BRABRADO6791
BBTBBta_0747
BRSS23_67390
AOLS58_06690
BRCBCCGELA001_34230
BICLMTR13_36370
BROBRAD285_6939
BRKCWS35_10155
BOTCIT37_08890
BRQCIT40_30030
BGQX265_34650
BGZXH91_33040
BSYMCIT39_29155
BBETF8237_13035
BARHWN72_46160
BVZBRAD3257_8649(hbaA)
BELBE61_90320
BDGLPJ38_02130
BSEPHAP48_0011945
BQBJ4P68_0015785
BSEIKMZ68_03440
BBANJ4G43_003765
RPARPA0669(hbaA)
RPBRPB_4656
RPCRPC_1016
RPDRPD_0878 RPD_1526
RPERPE_0592
RPTRpal_0736
RPXRpdx1_4117
RBKE0H22_11680
VGOGJW-30_1_01037(hbaA)
TRBHB776_18425
RHZRHPLAN_70010
LAPACP90_01135
LABRCHH27_19245
LABTFIU93_06225(bclA1)
LAGGB0E33_12635
SILSPO3697(badA-1)
JANJann_0669
RPONG3256_16625
SUAMBOO69_15590
SULZC1J03_02525
SMEDJNX03_11420
SPSESULPSESMR1_02749(hbaA)
TOMBWR18_14125
RIDRIdsm_00622(hbaA_1)
AHTANTHELSMS3_04347(prpE)
SAGUCDO87_17715
THAACFI11_22025
OCDFHY55_19220
MALUKU6B_38090
TGLHFZ77_06810
PTPRCA23_c19110
SEDIEBB79_19940
GCEKYE46_09665
MAGamb1551 amb2869
MAGXXM1_2792(bclA) XM1_3957(hcl)
MAGNWV31_08755 WV31_19615
 » show all
Reference
1  [PMID:2914844]
  Authors
Merkel SM, Eberhard AE, Gibson J, Harwood CS.
  Title
Involvement of coenzyme A thioesters in anaerobic metabolism of 4-hydroxybenzoate by Rhodopseudomonas palustris.
  Journal
J Bacteriol 171:1-7 (1989)
DOI:10.1128/JB.171.1.1-7.1989
Other DBs
ExplorEnz - The Enzyme Database: 6.2.1.27
IUBMB Enzyme Nomenclature: 6.2.1.27
ExPASy - ENZYME nomenclature database: 6.2.1.27
UM-BBD (Biocatalysis/Biodegradation Database): 6.2.1.27
BRENDA, the Enzyme Database: 6.2.1.27
CAS: 119699-80-8

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