KEGG   ENZYME: 6.2.1.34Help
Entry
EC 6.2.1.34                 Enzyme                                 

Name
trans-feruloyl-CoA synthase;
trans-feruloyl-CoA synthetase;
trans-ferulate:CoASH ligase (ATP-hydrolysing);
ferulate:CoASH ligase (ATP-hydrolysing)
Class
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
BRITE hierarchy
Sysname
ferulate:CoA ligase (ATP-hydrolysing)
Reaction(IUBMB)
ferulic acid + CoA + ATP = feruloyl-CoA + products of ATP breakdown [RN:R05744]
Reaction(KEGG)
Substrate
ferulic acid [CPD:C01494];
CoA [CPD:C00010];
ATP [CPD:C00002]
Product
feruloyl-CoA [CPD:C00406];
products of ATP breakdown [CPD:C07305]
Comment
Requires Mg2+. It has not yet been established whether AMP + diphosphate or ADP + phosphate are formed in this reaction.
History
EC 6.2.1.34 created 2000
Orthology
K12508  feruloyl-CoA synthase
Genes
XAL: XALC_3044
XSA: SB85_14035
PPU: PP_3356(fcs)
PPF: Pput_2402
PPW: PputW619_2049
PPUT: L483_17010 L483_20045
PFV: Psefu_4043
POR: APT59_07770
PST: PSPTO_2941(fcs)
PSB: Psyr_2726
PSYR: N018_13610
PSP: PSPPH_2435(fcs)
PPRC: PFLCHA0_c35170(fcs)
PPRO: PPC_3626
PFS: PFLU_3298
PSES: PSCI_1561(fadD)
PSEM: TO66_18480
PSOS: POS17_3611
ACX: Achr_28490(fcs)
ACB: A1S_1109
ABY: ABAYE2630(hcaC)
ABN: AB57_1193
ABAZ: P795_11780
ABAU: IX87_05300
ABAA: IX88_07795
ACC: BDGL_000389(hcaC)
ACI: ACIAD1724(hcaC)
PTN: PTRA_a0484(fcs)
CSA: Csal_0285
HEL: HELO_3953
HAM: HALO0097
RSO: RSp0227(fcs)
RSL: RPSI07_mp0180(fcs)
RSM: CMR15_mp10199(fcs)
RSE: F504_3666
CGD: CR3_2922(fcs)
BMA: BMA2967(fcs)
BMV: BMASAVP1_A3343(fcs)
BML: BMA10229_A1574(fcs)
BMN: BMA10247_3028(fcs)
BMAI: DM57_1688
BPD: BURPS668_3956(fcs)
BPR: GBP346_A4130(fcs)
BPK: BBK_1477
BPSO: X996_724
BUT: X994_2714
BTE: BTH_I3299
BTQ: BTQ_3235
BTJ: BTJ_2471
BTZ: BTL_414
BTD: BTI_174
BTV: BTHA_370
BTHE: BTN_979
BTHM: BTRA_588
BTHA: DR62_1143
BTHL: BG87_588
BOK: DM82_3111
BOC: BG90_1624
BVE: AK36_4868
BCJ: BCAL0046 BCAM2791(fcs)
BCEO: I35_0049 I35_6670(fcs)
BAM: Bamb_4914
BMU: Bmul_3212
BMK: DM80_4592
BMUL: NP80_3341
BDL: AK34_5015
BMEC: WJ16_32325
BGU: KS03_4871
BGO: BM43_7005
BUK: MYA_3499
BXE: Bxe_B2723
BXB: DR64_5056
RFR: Rfer_0273
POL: Bpro_3112
PNA: Pnap_0796
ACRA: BSY15_1661
DAC: Daci_0119
RTA: Rta_25010
CBAA: SRAA_0577
CBAB: SMCB_0807
LCH: Lcho_0993
EBA: ebA5317
DAR: Daro_3240
AZO: azo2499(fadD2)
AZA: AZKH_2162
AOA: dqs_2652
TCL: Tchl_1081
DAL: Dalk_3843
HOH: Hoch_2125
AMIH: CO731_05280(aas_2)
ATU: Atu1416
RHT: NT26_3191
RPA: RPA1707(fcs1) RPA1787(fcs2)
VGO: GJW-30_1_02157(lcfB_4)
MAQU: Maq22A_c00760(caiC)
PHL: KKY_2325
BVR: BVIR_1681
RBM: TEF_06255
SIL: SPO3696(fcs)
JAN: Jann_0667
CID: P73_1468
HNE: HNE_0167(fcs1) HNE_0864(fcs2)
SMAZ: LH19_17775
RCE: RC1_2522
MAG: amb2025
MAGX: XM1_2745
MAGN: WV31_19835
TMO: TMO_d0023(menE)
BAG: Bcoa_0611
GGH: GHH_c15090(lcfB3)
AFL: Aflv_1280
ANM: GFC28_461
AAMY: GFC30_1797
LSP: Bsph_0963
CVA: CVAR_2984(fadD4)
RER: RER_59160
REY: O5Y_28480
SALB: XNR_0513
SLAU: SLA_2125
BSD: BLASA_2535(fadD2)
PDX: Psed_5917
ABAC: LuPra_04020(lcfB_2)
SLI: Slin_1560
 » show all
Taxonomy
Reference
1  [PMID:9611814]
  Authors
Narbad A, Gasson MJ.
  Title
Metabolism of ferulic acid via vanillin using a novel CoA-dependent pathway in a newly-isolated strain of Pseudomonas fluorescens.
  Journal
Microbiology 144 ( Pt 5):1397-405 (1998)
DOI:10.1099/00221287-144-5-1397
Reference
2  [PMID:6870241]
  Authors
Pometto AL 3rd, Crawford DL.
  Title
Whole-cell bioconversion of vanillin to vanillic acid by Streptomyces viridosporus.
  Journal
Appl Environ Microbiol 45:1582-5 (1983)
Other DBs
ExplorEnz - The Enzyme Database: 6.2.1.34
IUBMB Enzyme Nomenclature: 6.2.1.34
ExPASy - ENZYME nomenclature database: 6.2.1.34
BRENDA, the Enzyme Database: 6.2.1.34

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