KEGG   ENZYME: 6.2.1.34
Entry
EC 6.2.1.34                 Enzyme                                 
Name
trans-feruloyl-CoA synthase;
trans-feruloyl-CoA synthetase;
trans-ferulate:CoASH ligase (ATP-hydrolysing);
ferulate:CoASH ligase (ATP-hydrolysing)
Class
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
Sysname
ferulate:CoA ligase (ATP-hydrolysing)
Reaction(IUBMB)
ferulic acid + CoA + ATP = feruloyl-CoA + products of ATP breakdown [RN:R05744]
Reaction(KEGG)
R05744
Substrate
ferulic acid [CPD:C01494];
CoA [CPD:C00010];
ATP [CPD:C00002]
Product
feruloyl-CoA [CPD:C00406];
products of ATP breakdown [CPD:C07305]
Comment
Requires Mg2+. It has not yet been established whether AMP + diphosphate or ADP + phosphate are formed in this reaction.
History
EC 6.2.1.34 created 2000
Orthology
K12508  feruloyl-CoA synthase
Genes
XALXALC_3044
XSASB85_14035
DTADYST_01081
PPUPP_3356(fcs)
PPFPput_2402
PPWPputW619_2049
PPUTL483_20045
PFVPsefu_4043
PORAPT59_07770
PSTPSPTO_2941(fcs)
PSBPsyr_2726
PSYRN018_13610
PSPPSPPH_2435(fcs)
PAMGBKM19_016445
PAVLBKM03_14280
PVDCFBP1590__2834
PCABJGS08_12755
PCOFPOR16_12655
PTREI9H09_12410
PSYIMME58_14245
PPRCPFLCHA0_c35170(fcs)
PPROPPC_3626
PFEPSF113_2661
PFSPFLU_3298
PPZH045_05710
PTVAA957_00720
PCGAXG94_01500
PVRPverR02_12205 PverR02_14380
PAZOAYR47_20530
PMEDE3Z27_15100
PLULFOB45_07575
PBAPSEBR_a3134
PBCCD58_14295
PSKU771_11780
PCHEY04_17950
PCZPCL1606_25840
PCPJM49_13000
PFZAV641_10370
PSESPSCI_1561(fadD)
PSEMTO66_18480
PSOSPOS17_3611
PPSLBJP27_22600
POJPtoMrB4_29610
PPSHG5J76_17040
PVKEPZ47_14275
PEZHWQ56_17500
PBZGN234_04235
PQIKH389_15735
PASGKSS96_11845
PALVKSS97_15860
PZAHU749_014420
PJUL1P09_10215
AVNAvin_14250(fcs) Avin_42140
AVLAvCA_14250(fcs) AvCA_42140
AVDAvCA6_14250(fcs) AvCA6_42140
ACXAchr_28490(fcs)
PURAOC03_11605
ACBA1S_1109
ABYABAYE2630(hcaC)
ABNAB57_1193
ABBABBFA_02403(fadD_2)
ABABBJAB0715_01299
ABAZP795_11780
ABAUIX87_05300
ABAAIX88_07795
ABALABLAC_19500
ACCBDGL_000389(hcaC)
ANORR32_12625
ALCOTEC02_13370
ACALBUM88_05400
ASEII8T81_13400
ACDAOLE_13755
ACIACIAD1724(hcaC)
AEIAOY20_07245
AHLAHTJS_11630
ASOLBEN76_04865
AUGURS_0071
ATNFM020_02770
PTNPTRA_a0484(fcs)
GAGGlaag_3892
KIMG3T16_07545
APRSBI364_09705
CSACsal_0285
HELHELO_3953
HAKKO116_00193
HAMHALO0097
HOLHORIV_71050
HSRHSBAA_65120
HMDCTT34_17600
HTTHZS52_05300
HCAMI4484_18960
HSXHNO51_19015
HSVHNO53_19305
HPROLMS44_23190
MMWMmwyl1_3017
MMEMarme_2601
MPCMar181_1044
MPRIMP3633_1210(fcs) MP3633_3151
MARDIBG28_06890
MFOIJSY38_15855
MPRFJ8N69_12530
MGEOCFI10_06040
MSECLN244_04505
MARLHH196_06515 HH196_06895
SDFACG33_11805
NBLGJV52_02865
VFFVITFI_CDS1568 VITFI_CDS3133
VITADP71_15840
VSTLVJ81_05630
RSORSp0227(fcs)
RSLRPSI07_mp0180(fcs)
RSNRSPO_m00216(fcs)
RSMCMR15_mp10199(fcs)
RSEF504_3666
RSYRSUY_35610(car)
RPJN234_06405 N234_29165
RPUCDC45_18750
CUHBJN34_12640 BJN34_26315 BJN34_26420
REUReut_B4165 Reut_B4868
RMERmet_3818 Rmet_5023
CGDCR3_2922(fcs)
CCUPBKK81_23765 BKK81_29975
CUPBKK80_26380 BKK80_32535
CUUBKK79_23500 BKK79_32265
BMABMA2967(fcs)
BMVBMASAVP1_A3343(fcs)
BMLBMA10229_A1574(fcs)
BMNBMA10247_3028(fcs)
BMALDM55_1001
BMAEDM78_96
BMAQDM76_976
BMAIDM57_1688
BMAFDM51_2578
BMAZBM44_323
BMABBM45_2937
BPSBPSL3387 BPSS0781
BPMBURPS1710b_0163(fcs) BURPS1710b_A2363(fcs)
BPLBURPS1106A_4030(fcs) BURPS1106A_A1069(fcs)
BPDBURPS668_3956(fcs)
BPRGBP346_A4130(fcs)
BPSEBDL_1992 BDL_4063
BPSMBBQ_3451 BBQ_5361
BPSUBBN_36 BBN_4235
BPSDBBX_383 BBX_5901
BPZBP1026B_I3675 BP1026B_II0858
BPQBPC006_I4065 BPC006_II1093
BPKBBK_1477
BPSHDR55_1119 DR55_4560
BPSABBU_2149 BBU_5257
BPSOX996_724
BUTX994_2714
BTEBTH_I3299
BTQBTQ_3235
BTJBTJ_2471
BTZBTL_414
BTDBTI_174
BTVBTHA_370
BTHEBTN_979
BTHMBTRA_588
BTHADR62_1143
BTHLBG87_588
BOKDM82_3111
BOCBG90_1624
BUUWS70_00630
BSAVWS86_01045 WS86_22705
BHGI6G56_00140 I6G56_19985
BVIBcep1808_3843
BVEAK36_4868
BURBcep18194_A3296 Bcep18194_B0052
BCMBcenmc03_0130 Bcenmc03_4595 Bcenmc03_6831
BCHBcen2424_0116 Bcen2424_5634
BCJBCAL0046 BCAM2791(fcs)
BCENDM39_5 DM39_5054
BCEWDM40_3358 DM40_891
BCEOI35_0049 I35_6670(fcs)
BAMBamb_4914
BACBamMC406_0116 BamMC406_5463
BMUBmul_3212
BMKDM80_4592
BMULNP80_3341
BCTGEM_0110 GEM_5616
BCEDDM42_1663 DM42_5197
BCEPAPZ15_04515 APZ15_24550
BDLAK34_5015
BPYRABD05_06610 ABD05_21680
BCONNL30_17800 NL30_18945
BUBBW23_1596 BW23_3979
BDFWI26_26515
BLATWK25_02125 WK25_29370
BTEIWS51_10595 WS51_11395
BSEMWJ12_00610 WJ12_33815
BPSLWS57_00310 WS57_13550
BMECWJ16_32325
BSTGWT74_00710 WT74_32680
BSTLBBJ41_10145 BBJ41_27775
BANNJFN94_00555 JFN94_17975
BGLbglu_2g10500
BGUKS03_4871
BUGBC1001_3919
BGFBC1003_5481
BGDbgla_2g02350
BGOBM43_7005
BYIBYI23_D012990
BUKMYA_3499
BUEBRPE67_DCDS01670
BULBW21_247 BW21_6347
BUQAC233_21885
BGPBGL_2c16150
BPLAbpln_2g16820
BUDAQ610_00635 AQ610_19080
BUMAXG89_39420
BUIAX768_20965
BURKDM992_03320 DM992_25715
BXEBxe_B2723
BXBDR64_5056
BGEBC1002_5525
BPXBUPH_00503
BPYBphyt_4024
BUZAYM40_26545
BCAIK788_0005931
PSPWBJG93_19800 BJG93_29035
PARBCJU94_22030 CJU94_29865
PHSC2L64_47325
PTERC2L65_02785 C2L65_07680
PGPCUJ91_21640
PCJCUJ87_23305
PTSCUJ90_22605
PGISI6I06_26890
PACPFAZ97_09570 FAZ97_28985 FAZ97_33760
PACSFAZ98_09130 FAZ98_16190
PDIOPDMSB3_0333.1
PPKU875_11035 U875_18590
PPNODA70_03445 DA70_11105
PPNMLV28_02880 LV28_19950
PRBX636_15520 X636_23665
PPULRO07_14160 RO07_21745
PSPUNA29_15345 NA29_22950
PAPISG18_13985 SG18_20710
PVEUC34_05425 UC34_13085
POXMB84_09815 MB84_17610
PFGAB870_00155 AB870_16395
PNRAT302_01610 AT302_19070
PANDDRB87_04715
PFIBPI93_014880 PI93_022975
PCOMNTU39_06285 NTU39_14685
BUOBRPE64_DCDS06660
BOJCBF45_06590
PUDG9Q38_01265 G9Q38_04070 G9Q38_04640 G9Q38_06520 G9Q38_10090
PIGEGT29_13925
KGYEHF36_07025
RFRRfer_0273
RSBRS694_00920
RHYRD110_11720
RHFEUB48_13065
RHOAHZ993_17695
POLBpro_3112
PNAPnap_0796
ACKC380_01280 C380_20115
ACRABSY15_1661
ACIOEAG14_20810
AANTHUK68_18615
ARADKI609_01250
DACDaci_0119
DELDelCs14_0121
DTSBI380_22335
DHKBO996_02400
DLAI6G47_22295
VAPVapar_0071 Vapar_4403
VPEVarpa_0088 Varpa_5066
VPDVAPA_1c00780 VAPA_1c45760
VAAAX767_13920
VBOCKY39_00425 CKY39_27685 CKY39_32610
VAMC4F17_18660 C4F17_23695
CTTCtCNB1_0213 CtCNB1_4138 CtCNB1_4793
CTESO987_24725 O987_28465
RTARta_25010
LIML103DPR2_01476
LIHL63ED372_00988
HYRBSY239_2239
HYBQ5W_08960 Q5W_19505
HYLLPB072_16175
HYCE5678_08860
HPSEHPF_07970
HYNF9K07_12115
HTNKI616_18250
CBAASRAA_0577
CBABSMCB_0807
STHMIS481_07640
SNNEWH46_00390 EWH46_03160
ATERMW290_20375 MW290_24495
HSEHsero_4007
HSZACP92_20005
HRBHrubri_3961
HEEhmeg3_01125
HHFE2K99_20865
HFRG5S34_21755
MASWAM586_11535
MALIEYF70_13780
MUMFCL38_05955
MFLAGO485_00010
LCHLcho_0993
RGUA4W93_06700
SHDSUTH_01231
EBAebA5317
ABREpbN1_04100
APETToN1_09330
DARDaro_3240
AZOazo2499(fadD2)
AOAdqs_2652
AZAAZKH_2162
AZIAzCIB_2732
AZDCDA09_14725
AZRCJ010_02380 CJ010_15720
TMZTmz1t_2493
TCLTchl_1081
THKCCZ27_17840
TAKTharo_1119
DDZDSYM_23760
BEBABWI17_21015
MFBMFUL124B02_10345
CCROCMC5_051700
PAUUE8A73_024205
LLUAKJ09_04057
MRMA7982_04802
HOHHoch_2125
DTIDesti_5477
MESOBSQ44_21455
AAKAA2016_5978
AMIHCO731_05280(aas_2)
NIYFQ775_08090 FQ775_21485
ORMHTY61_05130 HTY61_17340
PLAPlav_0753 Plav_1661
PMOBHG718_00730 HG718_09860
RBSRHODOSMS8_00298(lcfB)
ESJSJ05684_b59730
EAKEKH55_4150
ATUAtu1416
ALFCFBP5473_16035
AVQHRR99_21625
NGLRG1141_CH41210
NGGRG540_CH41730
NEOCYG48_15385
RHTNT26_3191
RFVRFYW14_03204
PDESFE840_020145
BJAbll7802(bll7802) blr1046(blr1046) blr7845(blr7845)
BJUBJ6T_10710 BJ6T_15390 BJ6T_84680
BJPRN69_05225 RN69_07605 RN69_40920
BRABRADO0933 BRADO0963 BRADO1099(fadD)
BBTBBta_5153 BBta_6949(fadD) BBta_7092 BBta_7119
BRSS23_09430 S23_63630 S23_67600
AOLS58_12060 S58_66660 S58_66910
BRCBCCGELA001_05135 BCCGELA001_33010 BCCGELA001_34425
BRADBF49_3225 BF49_4144
BICLMTR13_30240 LMTR13_35505 LMTR13_35635 LMTR13_36480
BROBRAD285_0429 BRAD285_0458 BRAD285_0616
BRKCWS35_02975 CWS35_03160 CWS35_10055
BOTCIT37_06575 CIT37_09070 CIT37_16740 CIT37_35530 CIT37_36420
BRQCIT40_02980 CIT40_28180 CIT40_30215
BGQX265_32795 X265_33280 X265_34805
BGZXH91_31215 XH91_31680 XH91_33170
BSYMCIT39_01400 CIT39_27195 CIT39_29320
BBETF8237_11175 F8237_13155 F8237_19630
BARHWN72_05960 WN72_43785 WN72_46350
BVZBRAD3257_0957 BRAD3257_1853 BRAD3257_8267 BRAD3257_8680
BELBE61_13940 BE61_14320 BE61_90520
BDGLPJ38_00685 LPJ38_02295 LPJ38_09435
BSEPHAP48_0012055 HAP48_0018805 HAP48_0019030
BQBJ4P68_0015910 J4P68_0022345 J4P68_0022525
RPARPA1707(fcs1) RPA1787(fcs2)
RPBRPB_1686 RPB_3577
RPDRPD_1887 RPD_3607
RPERPE_3802 RPE_3824
RPTRpal_1907 Rpal_1989
RPXRpdx1_3745 Rpdx1_3817
RBKE0H22_11640 E0H22_20665 E0H22_20785
VGOGJW-30_1_02157(lcfB_4)
TRBHB776_16030 HB776_16150 HB776_18395
MAQUMaq22A_c00760(caiC)
MEEDA075_12465
MTEADK419_20360
MINDmvi_14930
MLGCWB41_06760
RHZRHPLAN_69950
PHLKKY_2325
DEQXM25_21125
DEIC4375_05490
DSALK1X15_01015
DEVOH4N61_07400
YTIFNA67_02445
BVRBVIR_1681
BLAGBLTE_16410
MAADAZF01_17875 AZF01_20090
MLUTJET14_00300 JET14_17575
BRND1F64_22340
PSINCAK95_06175 CAK95_24130 CAK95_26315
RBMTEF_06255
PPHRAPZ00_05260
LAPACP90_06335
LABTFIU93_11975(car)
LAGGB0E33_17885
PHRC6569_04910
PSTGE8M01_13645
ACUTMRB58_01590
CCRCC_0391 CC_3338
CCSCCNA_00395 CCNA_03446
CAKCaul_4340 Caul_4356
CSECseg_0369 Cseg_0589 Cseg_3072
CHQAQ619_01630 AQ619_01970
CMBCSW64_04675 CSW64_17590
CFHC1707_02975
CAUFCSW63_20390
CAULKCG34_05755
PZUPHZ_c0568(fcs) PHZ_c1128 PHZ_c2519 PHZ_c2557
PHBHYN04_03265
BSBBresu_2041
BPONIFE19_04205
TSVDSM104635_03082(fadD)
SILSPO3696(fcs)
JANJann_0667
CIDP73_1468
CEHCEW89_18680
YPACCEW88_03010
YANAYJ57_10055
SUAMBOO69_11800
SULZC1J03_19945
SMEDJNX03_11425
SPSESULPSESMR1_00297(car) SULPSESMR1_02750(fadK)
AHTANTHELSMS3_02512
SAGUCDO87_15350 CDO87_17710
OCDFHY55_02040
MALUKU6B_33490 KU6B_34300
TGLHFZ77_07800 HFZ77_13885
TMDKUV46_07295 KUV46_09790
PALXGQA70_07075
RSHRsph17029_3634
RSKRSKD131_4304
PAMIJCM7686_1719
PAROCUV01_04000 CUV01_04025
PTPRCA23_c26170
RBGBG454_07450
SALOEF888_01200
PPRUFDP22_14610
PSHQF3W81_00385 F3W81_12685
PALWPSAL_022620(menE)
PGVSL003B_2870
GCEKYE46_16950
NSMJO391_18155
AMAQGO499_03930
GAKX907_1095
HNEHNE_0167(fcs1) HNE_0864(fcs2)
HBCAEM38_06180
SPHKSKP52_00900
SMAZLH19_17775
STERAOA14_04390
SPAPH3Z74_06745
SCHSphch_0173 Sphch_3440
SAMISAMIE_1033790
SPHGAZE99_00470
SPHYCHN51_12620
BLASBSY18_3601
PALGHFP57_02470
POQKZX46_02115 KZX46_08035
EFVCHH26_04925
SMUCJL100_030000
RCERC1_2522
MAGamb2025
MAGXXM1_2745
MAGNWV31_19835
TMOTMO_d0023(menE)
FERFNB15_04285 FNB15_11970
TIIDY252_19165
THAIIT893_02225
NACINUH88_16335
ECOGFIV45_10440
SNEANBZ79_08685
PARHI5S86_11640
SCIAHUG15_15535
CTHUHUR95_16285
BBEBBR47_15980
BFMBP422_03185
BAGRBA6348_20925
CVACVAR_2984(fadD4)
CGYCGLY_11165
RHARHA1_ro03467
RERRER_59160
REYO5Y_28480
REBXU06_28810
RQIC1M55_30295
ROAPd630_LPD07848
RHODAOT96_09945
RTMG4H71_10785
RKOJWS14_18260
RGOKYT97_19095
GOQACH46_08415 ACH46_13105
GOCCXX93_14415
GOILK459_12050
TOYFO059_00820
SALBXNR_0513
SKYD0C37_04100
SLAUSLA_2125
SRJSRO_7307
SGFHEP81_07635
XYLET495_09555
CETB8281_02925
BRIFDF13_06845
AGRAAGRA3207_003369
BSDBLASA_2535(fadD2)
AMYYYIM_25720(pqsA)
AORISD37_26730
PDXPsed_5917
ACTRAsp14428_19740
AEYCDG81_18365
SBAEDSM104329_00772(menE_1) DSM104329_01955
ABACLuPra_04020(lcfB_2)
HHYHalhy_0463
SPSCE2P86_04795
SLISlin_1560
SPIRCWM47_14215
SPIKEXU85_00750
SRHOHH216_17385
RHOZGXP67_01725
RSIRunsl_0510
RUPDTQ70_10435
EOLEmtol_1592
MARBCJ263_16350
EMARD1013_02550
 » show all
Reference
1  [PMID:9611814]
  Authors
Narbad A, Gasson MJ
  Title
Metabolism of ferulic acid via vanillin using a novel CoA-dependent pathway in a newly-isolated strain of Pseudomonas fluorescens.
  Journal
Microbiology 144 ( Pt 5):1397-405 (1998)
DOI:10.1099/00221287-144-5-1397
Reference
2  [PMID:6870241]
  Authors
Pometto AL 3rd, Crawford DL.
  Title
Whole-cell bioconversion of vanillin to vanillic acid by Streptomyces viridosporus.
  Journal
Appl Environ Microbiol 45:1582-5 (1983)
DOI:10.1128/AEM.45.5.1582-1585.1983
Other DBs
ExplorEnz - The Enzyme Database: 6.2.1.34
IUBMB Enzyme Nomenclature: 6.2.1.34
ExPASy - ENZYME nomenclature database: 6.2.1.34
BRENDA, the Enzyme Database: 6.2.1.34

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