KEGG ENZYME: 6.2.1.41

ENZYME: 6.2.1.41

Entry

EC 6.2.1.41                 Enzyme

Name

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate---CoA ligase;
fadD3 (gene name);
HIP---CoA ligase

Class

Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases

Sysname

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate:CoA ligase (AMP-forming)

Reaction(IUBMB)

ATP + 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + CoA = AMP + diphosphate + 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA [RN:R10769]

Reaction(KEGG)

R10769

Substrate

ATP [CPD:C00002];
3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate [CPD:C20199];
CoA [CPD:C00010]

Product

AMP [CPD:C00020];
diphosphate [CPD:C00013];
3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA [CPD:C20838]

Comment

The enzyme, characterized from actinobacterium Mycobacterium tuberculosis, catalyses a step in the degradation of cholesterol and cholate. The enzyme is very specific for its substrate, and requires that the side chain at C17 is completely removed.

History

EC 6.2.1.41 created 2014

Pathway

ec00984

Steroid degradation

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K18687

HIP---CoA ligase

Genes

RGL:	CS053_01725

VAF:	D1115_23235

PRE:	PCA10_43630

PFUW:

KF707C_11910

PPUT:

L483_14110

PPUN:

PP4_27170

PPUU:

PputUW4_01676

PKC:	PKB_4307 PKB_4315

PFZ:	AV641_10585

PLQ:	AA042_20385

PPSY:

AOC04_07885

PSET:

THL1_4405

PSIL:

PMA3_11755

PKE:	DLD99_14685

PUM:	HGP31_20740

PPSH:

G5J76_13540

PLAL:

FXN65_21115

PKH:	JLK41_05755

PAZE:

KSS91_19215

PTAE:

NCTC10697_02067(fadD_1)

PCAV:

D3880_17445

PPHN:

HU825_14705

PIZ:	LAB08_R40810

PKM:	PZ739_11590

PSHS:

JJN09_05490

PFOU:

OZ911_14125

SDEG:

GOM96_01710

HARR:

HV822_17930

PPHA:

BVH74_17915

KAK:	Kalk_07825

SPL:

Spea_2126

SHL:

Shal_2098

CBER:

B5D82_11310

PHA:

PSHAa2132

PTN:	PTRA_a2585

PNG:	PNIG_a2779

SNAN:

I6N98_06920

ZAL:	AZF00_05245

HALC:

EY643_14275

AFUS:

EYZ66_12945

PAQM:

E0F26_07495

MSEC:

LN244_04845

MRZ:	KDW95_00840

ENW:	MJO57_21325

EMP:	EZMO1_1276

SDF:	ACG33_03745 ACG33_09100

SOK:	D0B54_05255

SINI:

GT972_08475

FCE:	JN531_005465

GPB:	HDN1F_27370

RIN:	ACS15_4389

REH:	H16_B0644(h16_B0644)

CNC:	CNE_2c05910(yngI) CNE_BB1p00170

CUH:	BJN34_30920

REU:	Reut_A1547

CTI:	RALTA_B0493

CBW:	RR42_s2339

COX:	E0W60_08165

CUK:	KB879_20660

BUR:	Bcep18194_B1417

BCJ:

BCAM1643

BCEN:

DM39_6207

BCEO:

I35_5503

BCT:	GEM_4013 GEM_4107

BCED:

DM42_6315

BCEP:

APZ15_30840

BPYR:

ABD05_27660

BCON:

NL30_03970

BDF:	WI26_21165 WI26_21350

BTEI:

WS51_05840

BPSL:

WS57_05870

BMEC:

WJ16_26950

BSTL:

BBJ41_21505

BANN:

JFN94_25670 JFN94_26150

BARI:

NLX30_30005

BAEN:

L3V59_21915

BURK:

DM992_32475

BFN:

OI25_4610

PBRY:

NDK50_32985

PPAI:

E1956_20160 E1956_37115

PVE:	UC34_06910

CABA:

SBC2_48800(fadD3_3)

CTT:	CtCNB1_1360

CTES:

O987_07775

CRJ:	QMY55_07055

DIH:	G7047_09740

SMIO:

CATMQ487_31530(fadD3)

DOE:	DENOEST_1378(fadD)

AZD:	CDA09_09375

THU:	AC731_008835

THAU:

C4PIVTH_4328(fadD)

THAG:

CKCBHOJB_02372(fadD3_1)

AAK:	AA2016_1500 AA2016_3673

AMIS:

Amn_27730 Amn_48420

TSV:	DSM104635_02997(lcfB_4)

GYJ:	AADW23_16360

NAR:

Saro_3767

NPP:	PP1Y_Mpl2929

NPN:	JI59_09720

NOT:	C7W88_20835

NGF:	FRF71_13155 FRF71_13260

SWI:	Swit_0310 Swit_0384 Swit_2105 Swit_3306

SPHD:

HY78_09020 HY78_14990 HY78_26180 HY78_26565

RDI:	CMV14_05515 CMV14_05925

SPHM:

G432_04705

SSAN:

NX02_14695

SPKC:

KC8_01165

SPHA:

D3Y57_15520

SLAN:

GV829_01960

SBIN:

SBA_ch2_4510(fadD3)

SCH:	Sphch_3617 Sphch_3631

SYB:	TZ53_05605 TZ53_05675

SYA:	A6768_12225 A6768_12295

SUFL:

FIL70_22020 FIL70_22090

SBAR:

H5V43_18870 H5V43_18940

PHAO:

HF685_05620

PHZ:	CHX26_05220

NTD:	EGO55_13795

CAEN:

K5X80_14620

NAO:	Y958_14665

THAR:

T8K17_24510

GSO:	PH603_03620

MTU:	Rv3561(fadD3)

MTV:

RVBD_3561

MTC:

MT3666

MRA:	MRA_3600(fadD3)

MTF:	TBFG_13594

MTB:	TBMG_03600

MTK:	TBSG_03627

MTZ:	TBXG_003576

MTG:	MRGA327_21990

MTI:	MRGA423_22505

MTE:	CCDC5079_3302

MTUR:

CFBS_3777(fadD3)

MTL:	CCDC5180_3254

MTO:	MTCTRI2_3625(fadD3)

MTD:	UDA_3561(fadD3)

MTN:	ERDMAN_3906(fadD3)

MTJ:	J112_19175

MTUB:

MT7199_3623

MTUE:

J114_19045

MTX:	M943_18305

MTUH:

I917_24990

MTUL:

TBHG_03501

MTUT:

HKBT1_3762(fadD3)

MTUU:

HKBT2_3771(fadD3)

MTQ:	HKBS1_3774(fadD3)

MBO:	BQ2027_MB3591(fadD3)

MBB:	BCG_3625(fadD3)

MBT:	JTY_3626(fadD3)

MBM:	BCGMEX_3623(fadD3)

MBK:	K60_036990

MBX:

BCGT_3427

MAF:	MAF_35730(fadD3)

MMIC:

RN08_3938

MCE:	MCAN_35721(fadD3)

MCQ:	BN44_110053(fadD)

MCV:	BN43_90059(fadD)

MCX:	BN42_90058(fadD)

MCZ:	BN45_100060(fadD)

MORY:

MO_003718(fadD3)

MPA:	MAP_0506c(fadD3) MAP_0780(fadD3)

MAO:	MAP4_3079 MAP4_3361

MAVI:

RC58_15265 RC58_16670

MAVU:

RE97_15295 RE97_16705

MAV:	MAV_0600(fadD) MAV_0971

MIT:	OCO_05090 OCO_08360

MIA:	OCU_05130 OCU_08440

MID:	MIP_00953 MIP_01417

MYO:	OEM_05150 OEM_08450

MCHI:

AN480_02540 AN480_05365

MIR:	OCQ_05240 OCQ_08520

MMAL:

CKJ54_02480 CKJ54_04170

MLP:

MLM_0744

MMAN:

MMAN_48040(fadD3) MMAN_51360

MSER:

MTY59_24390(fadD3) MTY59_27620

MSA:	Mycsm_04438 Mycsm_05824

MUL:	MUL_4126(fadD3)

MMI:	MMAR_4688(fadD3_2) MMAR_5050(fadD3)

MMAE:

MMARE11_45140(fadD3_2) MMARE11_48650(fadD3)

MLI:	MULP_05308(fadD3)

MPSE:

MPSD_48500 MPSD_52500(fadD3)

MSHO:

MSHO_05320(fadD3)

MMC:	Mmcs_3655 Mmcs_4694

MKM:	Mkms_3728 Mkms_4780

MJL:	Mjls_3668 Mjls_5079

MMM:	W7S_02485 W7S_04130

MKN:	MKAN_09685 MKAN_12040

MYV:	G155_20365 G155_26340

MYE:	AB431_21360 AB431_26505

MHAD:

B586_04505

MDX:	BTO20_04540 BTO20_10895

MSHG:

MSG_04223 MSG_04547(fadD3)

MFJ:	MFLOJ_40780(fadD3) MFLOJ_44090

MSTO:

MSTO_44750(fadD3) MSTO_48100

MSIM:

MSIM_29200(fadD3) MSIM_32550

MSAK:

MSAS_25700 MSAS_29040(fadD3)

MKU:	I2456_22325 I2456_25635

MLW:	MJO58_23390 MJO58_25035(fadD3)

MXE:	MYXE_05150(fadD3) MYXE_11440

MNV:	MNVI_09050 MNVI_12420(fadD3)

MPAG:

C0J29_25770 C0J29_27710

MNM:	MNVM_23560(fadD3) MNVM_26540

MGOR:

H0P51_24020 H0P51_25765

MCOO:

MCOO_23770 MCOO_27190(fadD3)

MBAI:

MB901379_04092(lcfB_14) MB901379_04440(lcfB_16)

MSEO:

MSEO_31260 MSEO_34450(fadD3)

MHEK:

JMUB5695_00476(fadD3) JMUB5695_00690 JMUB5695_01061

MGAU:

MGALJ_25030 MGALJ_38370(fadD3)

MLJ:	MLAC_47430(fadD3)

MBRD:

MBRA_20090(fadD3) MBRA_24120 MBRA_50720

MSHJ:

MSHI_38740(fadD3)

MMAM:

K3U93_03775 K3U93_22640(fadD3)

MSPG:

F6B93_20445

MOT:	LTS72_01860 LTS72_27960(fadD3)

MPAA:

MKK62_02450(fadD3) MKK62_04030

MKY:	IWGMT90018_53750 IWGMT90018_57380(fadD3)

MADI:

A7U43_06735 A7U43_11555

MWU:	PT015_13820 PT015_15515(fadD3)

MYW:	BVC93_09215

MSM:	MSMEG_4772

MSG:	MSMEI_4650 MSMEI_5853(fadD3)

MSB:	LJ00_23605 LJ00_29730

MSN:	LI99_23610 LI99_29735

MSH:	LI98_23615 LI98_29740

MVA:	Mvan_4133 Mvan_5286

MGI:	Mflv_1480 Mflv_2525

MSP:	Mspyr1_19520 Mspyr1_46870

MCB:	Mycch_3565 Mycch_4656

MNE:	D174_24625

MYN:	MyAD_24160

MFT:	XA26_41550 XA26_53340

MPHL:

MPHLCCUG_03698(lcfB_8)

MVQ:	MYVA_3927 MYVA_5196

MLL:	B1R94_25345

MRH:	MycrhN_2265 MycrhN_4054

MTHN:

4412656_02988(fadD_12) 4412656_04084(fadD_18)

MHAS:

MHAS_01072(fadD3_4) MHAS_03765(fadD3_6)

MDU:	MDUV_05460 MDUV_18420 MDUV_49150(fadD3)

MCHT:

MCHIJ_19460(fadD3) MCHIJ_29620

MAUU:

NCTC10437_03867(fadD_9) NCTC10437_05044(fadD_13)

MMAG:

MMAD_38850 MMAD_48440(fadD3)

MMOR:

MMOR_11950(fadD3) MMOR_24330

MFX:	MFAL_01670 MFAL_32670(fadD3)

MAIC:

MAIC_05290(fadD3) MAIC_37640

MIJ:	MINS_00620(fadD3) MINS_34900

MALV:

MALV_42360(fadD3) MALV_53670

MTY:	MTOK_22130(fadD3)

MPSC:

MPSYJ_15990(fadD3) MPSYJ_26800

MARZ:

MARA_47560(fadD3) MARA_58560

MGAD:

MGAD_37450(fadD3) MGAD_57520

MHEV:

MHEL_04750 MHEL_27740(fadD3)

MSAR:

MSAR_10910(fadD3) MSAR_47980

MANY:

MANY_13600 MANY_32920(fadD3)

MAUB:

MAUB_12420 MAUB_58040

MPOF:

MPOR_42530 MPOR_53740(fadD3)

MMUC:

C1S78_018185

MMAT:

MMAGJ_00400 MMAGJ_34150(fadD3)

MBOK:

MBOE_04690(fadD3) MBOE_32280

MFG:	K6L26_05485(fadD3) K6L26_11395

MSEI:

MSEDJ_02390(fadD3) MSEDJ_50120

MFLV:

NCTC10271_00480(fadD_1) NCTC10271_01606(fadD_7)

MCEE:

MCEL_00580 MCEL_37860(fadD3)

MMON:

EWR22_18865 EWR22_25395

MGO:	AFA91_10715 AFA91_16715

MHOL:

K3U96_03160(fadD3) K3U96_08810

MSEN:

K3U95_09565 K3U95_25370(fadD3)

MPAE:

K0O64_20895 K0O64_26000(fadD3)

MRF:	MJO55_18665 MJO55_24065(fadD3)

MDF:	K0O62_20330 K0O62_25855(fadD3)

MCRO:

MI149_21470 MI149_26310(fadD3)

MGRO:

FZ046_02880 FZ046_24070

MAUS:

JN090_20145 JN090_26475

MKR:	MKOR_35470(fadD3)

MPAK:

MIU77_02035(fadD3) MIU77_10645

MAB:

MAB_0596c

MMV:	MYCMA_0305

MABB:

MASS_0566

MABL:

MMASJCM_0585

MCHE:

BB28_02845

MIZ:	BAB75_03595

MSTE:

MSTE_00554

MSAO:

MYCSP_02550

MSAL:

DSM43276_00514

MJD:	JDM601_3424(fadD3_2) JDM601_3717(fadD3)

MTER:

4434518_03408(fadD3_2) 4434518_03719(fadD3)

MMIN:

MMIN_12410(fadD3)

MHIB:

MHIB_28310 MHIB_31060(fadD3)

MHER:

K3U94_19405 K3U94_20970(fadD3)

MVM:	MJO54_19365 MJO54_20865(fadD3)

ASD:

AS9A_0944

NFA:

NFA_4830

NFR:	ERS450000_03753(fadD_8)

NCY:	NOCYR_0513

NBR:	O3I_002775

NNO:	NONO_c05120 NONO_c41750 NONO_c58970

NSL:	BOX37_02240 BOX37_18195

NSR:	NS506_01276(acsL) NS506_06831

NTP:	CRH09_03385

NOZ:	DMB37_23675

NOD:	FOH10_22725 FOH10_28625

NAH:	F5544_02710

NAD:	NCTC11293_01257(fadD_1)

NWL:	NWFMUON74_05070 NWFMUON74_28700

NIE:	KV110_03105

NTC:	KHQ06_03580 KHQ06_35310

NHU:	H0264_03915 H0264_34430

NYA:	LTV02_28805 LTV02_38505

NGP:	LTT66_15515 LTT66_27885 LTT66_28685

NSPU:

IFM12276_01870(fadD3) IFM12276_28540

NYU:	D7D52_04580 D7D52_09685

RHA:	RHA1_ro04595

RER:

RER_08900

REY:

O5Y_03940

REB:	XU06_04180

RQI:	C1M55_04410

ROP:

ROP_45400

ROA:	Pd630_LPD01072

RPY:	Y013_19130

RBY:	CEJ39_05495

RAV:	AAT18_04025

RHW:	BFN03_15060

RRZ:	CS378_19670

RHQ:	IM25_08980

RHOD:

AOT96_14810

RRT:	4535765_00602(fadD_1) 4535765_04305(fadK_8)

RCR:	NCTC10994_02118(fadD_6) NCTC10994_03067(fadD_13)

RTM:	G4H71_07295

RKO:	JWS14_25305(fadD3)

RGO:	KYT97_13825 KYT97_23455 KYT97_24215

ROZ:	CBI38_04305 CBI38_05550

RPSK:

JWS13_19230

RGOR:

NMQ04_02615

RHOP:

D8W71_08025

RHOO:

RA302_04290

RHOU:

KZJ41_04020

RHOW:

A4U64_20750

RHOJ:

JVH1_13275(fadD3)

REQ:

REQ_07020

PDEF:

P9209_28960

WHR:	OG579_09490

GBR:

Gbro_3996

GPO:	GPOL_c43210

GOR:	KTR9_3925(fadD3)

GOQ:	ACH46_17650

GTA:	BCM27_20570

GIT:	C6V83_03810

GRU:	GCWB2_20060(lcfB19)

GOM:	D7316_02344(fadD3_4) D7316_04486(fadD3_6)

GAV:	C5O27_08040

GOD:	GKZ92_18990

GOS:	QAD21_19480

GOJ:	GR168_18825

GAM:	GII34_18975

GPD:	GII33_03785

GJI:	H1R19_18915

GOI:	LK459_13625

GHN:	MVF96_19510

GAMI:

IHQ52_23040

GMG:	NWF22_06475

GSI:	P5P27_16330

SPIN:

KV203_08665 KV203_17315

TPR:

Tpau_3836

TSM:	ASU32_21855

TPUL:

TPB0596_41760

TSD:	MTP03_43180

DTM:	BJL86_0717

DIT:	C3V38_09320

DIZ:	CT688_03240

DPC:	A6048_03185

DLU:	A6035_03480

DKN:	NHB83_03040

TOY:	FO059_13900

SMA:	SAVERM_3806(fadD16)

SGR:

SGR_3014

SGB:

WQO_20655

SFI:

SFUL_4340

SANL:

KZO11_21820

SGRF:

SGFS_054000

SCYE:

R2B67_14140

SCB:	SCAB_51911

SVL:	Strvi_0995

SRC:	M271_20830 M271_44415

SMAL:

SMALA_4570

SSOI:

I1A49_26910

SBH:

SBI_06310

SVE:

SVEN_3097

SDV:	BN159_5012(fadD16)

SCI:	B446_16925

SVT:	SVTN_16190 SVTN_35955

STRE:

GZL_01222 GZL_05169

SLD:

T261_4786

SLC:	SL103_02730

STRM:

M444_15600

SPRI:

SPRI_4275

SCZ:	ABE83_14545

SCX:	AS200_26045

SRW:	TUE45_04305(lcfB_5)

SCLF:

BB341_11710

SGS:	AVL59_44295

STSI:

A4E84_17385

SALW:

CP975_15095

SGM:	GCM10017557_35940(fadD3)

SCAD:

DN051_22275

SPHW:

NFX46_37245

SLS:	SLINC_3721

SNR:	SNOUR_23725

SALU:

DC74_3724 DC74_7422

SALL:

SAZ_19795 SAZ_38315

SPLU:

LK06_018885

SAUO:

BV401_26700

SSIA:

A7J05_20260

SVU:	B1H20_20855

SPUN:

BFF78_24005

SGV:	B1H19_18045

SLAU:

SLA_3151

SALF:

SMD44_03682

SALJ:

SMD11_3940

SLX:	SLAV_16680(lcfB3) SLAV_27185(fadD)

STRO:

STRMOE7_17095

SFK:

KY5_3519c

SNZ:	DC008_14850

SGE:	DWG14_04793(fadD3_2)

SRJ:

SRO_4198

SLK:	SLUN_17115

SDX:	C4B68_22860

SGD:	ELQ87_22140

SQZ:	FQU76_13315

SCYA:

EJ357_19865

STIR:

DDW44_13080

SKA:	CP970_24690

SGZ:	C0216_28150

SVN:	CP980_19310

SNK:	CP967_03170

SHAW:

CEB94_17835

SRK:	FGW37_13720

SFIC:

EIZ62_18905

SGAL:

CP966_15740

SSPO:

DDQ41_12980

SFY:	GFH48_23150 GFH48_36350

SAQU:

EJC51_22160

SGF:	HEP81_04370

SCAV:

CVT27_20050

SBY:	H7H31_00530

SRIM:

CP984_22865

SSUB:

CP968_19240

SPHV:

F9278_20570

STSU:

B7R87_12920

SCHA:

CP983_24260

SGX:	H4W23_17480 H4W23_38580

SCOE:

CP976_19305

SSPB:

CP982_19280

SNF:	JYK04_03879(fadD3)

SPLA:

CP981_16825

SBRO:

GQF42_20345

STUI:

GCM10017668_30020

SATA:

C5746_24045

SHUN:

DWB77_04404(fadD3_2)

SCYG:

S1361_17585(lcfB6)

SFEU:

IM697_04450

SDW:	K7C20_14855 K7C20_16105

SCAL:

I6J39_20675

SAUH:

SU9_014305

SPEU:

CGZ69_15455

SROI:

IAG44_23445

SXN:	IAG42_15145 IAG42_26605

SHK:	J2N69_15530

SANU:

K7396_20725

STRY:

EQG64_20815

SGOB:

test1122_09880

SINE:

KI385_19910

SLF:	JEQ17_20445

SDEC:

L3078_19850

SAOV:

G3H79_21015

SDUR:

M4V62_24190

SYAN:

NRK68_14635

SRUG:

F0345_00695

SAKB:

K1J60_24945

STAA:

LDH80_23025 LDH80_36450

SNIG:

HEK616_00360 HEK616_31540

SCAE:

IHE65_25495

STUB:

MMF93_14330 MMF93_22590 MMF93_31775

SSPN:

LXH13_23295

SCIR:

STRCI_003639

SXT:	KPP03845_103393(fadD3_2)

SLON:

LGI35_13980 LGI35_20860

STUD:

STRTU_004091

SGK:	PET44_14320

SANT:

QR300_18360

SYUN:

MOV08_04950 MOV08_24160

SJN:	RI060_24210

SCYN:

N8I84_18260

SOV:	QZH56_20725

SFIY:

F0344_14505

SHAU:

K9S39_25585

SKG:	KJK29_21545

SCOA:

QU709_24095 QU709_44410 QU709_44600

SLAI:

P8A22_16295

SROC:

RGF97_19250

SFP:	QUY26_22645

STTN:

BSL84_14370

SINN:

ABB07_21530

KBU:	Q4V64_22670 Q4V64_51225 Q4V64_51520

SLUO:

PS467_24615

STPB:

QR97_15015

SRPA:

HEP86_17725

SMIB:

SMIR_21265

SCAJ:

O1G22_23835

SCT:

SCAT_2351

SCY:	SCATT_23360

KAB:	B7C62_21185

STRI:

C7M71_000480

YIA:	LO772_06015 LO772_06250 LO772_20310 LO772_32330

STRH:

GXP74_36245

AGLA:

OIE69_23100

MRN:	K8F61_15875

MSUF:

KV394_02750

ARL:	AFL94_17015

ARY:	ATC04_01260

ASUN:

KG104_08915

GPR:	JQN66_16930

PAEY:

KUF55_17940

NCA:

Noca_2768

NDK:	I601_0619 I601_0635(lcfB_1)

NBE:	Back2_27300(fadD3)

NANO:

G5V58_09820

NARO:

CFH99_13485

NPI:	G7071_15905

NPC:	KUV85_04315

NMAR:

HPC71_09580

NFC:	KG111_08350

NBI:	SHK19_12435

PSIM:

KR76_25120 KR76_25165

AEB:	C6I20_03325

AWN:	NQV15_03990

NGV:	CDO52_09610

TCU:

Tcur_3475

ACTW:

F7P10_03615 F7P10_29035 F7P10_38160

AMAZ:

LUW76_15465

ACIR:

OG979_26685

SPIQ:

OHA34_33840 OHA34_37725

ACTQ:

OG417_40175

SRO:

Sros_2101

NOA:	BKM31_34195

NCX:	Nocox_09885(lcfB4)

NGN:	LCN96_11175

NFS:	OIE67_35875

FRE:	Franean1_4311

FRI:	FraEuI1c_4763

AMD:

AMED_3385

AMN:

RAM_17220

AMM:

AMES_3346

AMZ:

B737_3346

AOI:

AORI_2499

AJA:	AJAP_26330

AMQ:	AMETH_1197 AMETH_4459

AMYC:

CU254_23990

AMYB:

BKN51_05105

AAB:	A4R43_16000

AMYY:

YIM_33170(lcfB8)

AORI:

SD37_13550

AACD:

LWP59_29160

APRT:

MUY14_18565

AROO:

NQK81_09855

ATHM:

L1857_25360

ARHD:

VSH64_01855

AMOG:

QRX60_34270

ACYN:

ORV05_07305

ACOR:

LCL61_01305

PSEE:

FRP1_11590

PSEQ:

AD006_19380

PECQ:

AD017_27220

PHH:	AFB00_08730

PAUT:

Pdca_08270(fadD3)

PSDS:

K1T35_19725

KAL:

KALB_5110

KUT:	JJ691_29480

KPHY:

AOZ06_42705

LED:	BBK82_38875

ALO:

CRK57775

PMAD:

BAY61_15980 BAY61_16235

SACE:

GIY23_13320

CROS:

N8J89_29335

ACTY:

OG774_23310

STP:	Strop_2660

SAQ:

Sare_2861

MICB:

MicB006_5685

MCHL:

PVK74_03200

AMS:	AMIS_19270

AIH:	Aiant_18740

ACTL:

L3i22_084260

ASIC:

Q0Z83_065490

AOU:	ACTOB_004132

ACTE:

ACTI_41290

PSUU:

Psuf_059150 Psuf_059160

DVC:	Dvina_21455

DFU:	Dfulv_25890

DROS:

Drose_12930

DAUR:

Daura_27560

DMAT:

Dmats_17090

DACT:

KZZ52_23580 KZZ52_30535

CAI:

Caci_8762

JCY:	M6B22_17345

ABAI:

IMCC26256_111347

CWO:

Cwoe_2360

IAM:	HC251_08970

IMA:	PO878_13630

DHI:	LH044_03785 LH044_09930

» show all

Reference

1 [PMID:16891113]

Authors

Horinouchi M, Hayashi T, Koshino H, Kudo T

Title

ORF18-disrupted mutant of Comamonas testosteroni TA441 accumulates significant amounts of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid and its derivatives after incubation with steroids.

Journal

J Steroid Biochem Mol Biol 101:78-84 (2006)
DOI:10.1016/j.jsbmb.2006.06.006

Sequence

[ctt:CtCNB1_1360]

Reference

2 [PMID:23146019]

Authors

Casabon I, Crowe AM, Liu J, Eltis LD

Title

FadD3 is an acyl-CoA synthetase that initiates catabolism of cholesterol rings C and D in actinobacteria.

Journal

Mol Microbiol 87:269-83 (2013)
DOI:10.1111/mmi.12095