Entry
Name
4-hydroxybutyrate---CoA ligase (ADP-forming);
Nmar_0206 (locus name)
Class
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
BRITE hierarchy
Sysname
4-hydroxybutanoate:CoA ligase (ADP-forming)
Reaction(IUBMB)
ATP + 4-hydroxybutanoate + CoA = ADP + phosphate + 4-hydroxybutanoyl-CoA [RN:
R10758 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme, characterized from the marine ammonia-oxidizing archaeon Nitrosopumilus maritimus, participates in a variant of the 3-hydroxypropanoate/4-hydroxybutanate CO2 fixation cycle. cf. EC
6.2.1.40 , 4-hydroxybutyrate---CoA ligase (AMP-forming).
History
EC 6.2.1.56 created 2019
Pathway
ec00720 Other carbon fixation pathways
ec01120 Microbial metabolism in diverse environments
Orthology
K18593 4-hydroxybutyrate---CoA ligase (ADP-forming)
Genes
» show all
Taxonomy
Reference
Authors
Konneke M, Schubert DM, Brown PC, Hugler M, Standfest S, Schwander T, Schada von Borzyskowski L, Erb TJ, Stahl DA, Berg IA
Title
Ammonia-oxidizing archaea use the most energy-efficient aerobic pathway for CO2 fixation.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 6.2.1.56
ExPASy - ENZYME nomenclature database: 6.2.1.56