(1) ATP + a marinolic acid + CoA = AMP + diphosphate + a marinoloyl-CoA [RN:R12494];
(2) ATP + a pseudomonic acid + CoA = AMP + diphosphate + a pseudomonoyl-CoA [RN:R12495]
The enzyme, characterized from the bacterium Pseudoalteromonas sp. SANK 73390, catalyses the CoA acylation of pseudomonic and marinolic acids, as part of the biosynthesis of thiomarinols and related compounds.