KEGG   ENZYME: 6.2.1.9Help
Entry
EC 6.2.1.9                  Enzyme                                 

Name
malate---CoA ligase;
malyl-CoA synthetase;
malyl coenzyme A synthetase;
malate thiokinase
Class
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
BRITE hierarchy
Sysname
malate:CoA ligase (ADP-forming)
Reaction(IUBMB)
ATP + malate + CoA = ADP + phosphate + malyl-CoA [RN:R01256]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
malate [CPD:C00149];
CoA [CPD:C00010]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
malyl-CoA [CPD:C04348]
History
EC 6.2.1.9 created 1972
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
ec00680  Methane metabolism
ec01120  Microbial metabolism in diverse environments
Orthology
K08692  malate-CoA ligase subunit alpha
K14067  malate-CoA ligase subunit beta
Genes
PHD: 102320684
MCA: MCA1740(sucC-2) MCA1741(sucD-2)
MMT: Metme_2693 Metme_2694
MDN: JT25_000145 JT25_000150(sucC)
MDH: AYM39_08395(sucC) AYM39_08400
MKO: MKLM6_1753 MKLM6_1754
MAH: MEALZ_3215(mtkB) MEALZ_3216(mtkA)
MPSY: CEK71_18040 CEK71_18045
TSN: W908_06420 W908_06425(sucC)
BPH: Bphy_5926 Bphy_5927
METR: BSY238_255(sucD) BSY238_256(sucC)
AMIH: CO731_05426(sucC_2) CO731_05427(sucD_2)
SFH: SFHH103_02475(succ1) SFHH103_02476(sucd1)
SFD: USDA257_c22010(mtkB) USDA257_c22020(mtkA)
MEA: Mex_1p1730(mtkA) Mex_1p1731(mtkB)
MDI: METDI2482(mtkA) METDI2483(mtkB)
META: Y590_08600(sucC) Y590_08605
MAQU: Maq22A_c19260(mtkB) Maq22A_c19265(mtkA)
HMC: HYPMC_4393(mtkB) HYPMC_4394(mtkA)
FIL: BN1229_v1_1241(sucC) BN1229_v1_1242(sucD)
FIY: BN1229_v1_1239(sucC) BN1229_v1_1240(sucD)
MSC: BN69_1173 BN69_1174(sucC1)
HDI: HDIA_2218(sucC_1) HDIA_2219(sucD_2)
RDE: RD1_1162(mtkA) RD1_4246(mtkB)
RLI: RLO149_c036810(mtkB) RLO149_c036820(mtkA)
PAMN: pAMV1p0131(mtkA) pAMV1p0132(mtkB)
DSH: Dshi_2491(sucC2) Dshi_2492(sucD2)
 » show all
Taxonomy
Reference
1  [PMID:14244056]
  Authors
MUE S, TUBOI S, KIKUCHI G.
  Title
ON MALYL-COENZYME A SYNTHETASE.
  Journal
J Biochem 56:545-51 (1964)
Other DBs
ExplorEnz - The Enzyme Database: 6.2.1.9
IUBMB Enzyme Nomenclature: 6.2.1.9
ExPASy - ENZYME nomenclature database: 6.2.1.9
BRENDA, the Enzyme Database: 6.2.1.9
CAS: 37318-58-4

DBGET integrated database retrieval system