KEGG   ENZYME: 6.3.1.13
Entry
EC 6.3.1.13                 Enzyme                                 
Name
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase;
MshC;
MshC ligase;
Cys:GlcN-Ins ligase;
mycothiol ligase
Class
Ligases;
Forming carbon-nitrogen bonds;
Acid-D-ammonia (or amine) ligases (amide synthases)
Sysname
L-cysteine:1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol ligase (AMP-forming)
Reaction(IUBMB)
1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + L-cysteine + ATP = 1-O-[2-(L-cysteinamido)-2-deoxy-alpha-D-glucopyranosyl]-1D-myo-inositol + AMP + diphosphate [RN:R09591]
Reaction(KEGG)
R09591
Substrate
1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol [CPD:C19702];
L-cysteine [CPD:C00097];
ATP [CPD:C00002]
Product
1-O-[2-(L-cysteinamido)-2-deoxy-alpha-D-glucopyranosyl]-1D-myo-inositol [CPD:C19703];
AMP [CPD:C00020];
diphosphate [CPD:C00013]
Comment
This enzyme is a key enzyme in the biosynthesis of mycothiol, a small molecular weight thiol found in Mycobacteria spp. and other actinomycetes. Mycothiol plays a fundamental role in these organisms by helping to provide protection from the effects of reactive oxygen species and electrophiles, including many antibiotics. The enzyme may represent a novel target for new classes of antituberculars [2].
History
EC 6.3.1.13 created 2009
Orthology
K15526  L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase
Genes
MTURv2130c(mshC)
MTVRVBD_2130c
MTCMT2188(cysS-1)
MRAMRA_2144(cysS1)
MTFTBFG_12161
MTBTBMG_01851
MTKTBSG_01863
MTZTBXG_001834
MTGMRGA327_13125
MTIMRGA423_13240
MTECCDC5079_1969
MTURCFBS_2257(cysS1)
MTLCCDC5180_1943
MTOMTCTRI2_2165(cysS)
MTDUDA_2130c(cysS2)
MTNERDMAN_2347(cysS)
MTJJ112_11410
MTUBMT7199_2160(mshC)
MTUCJ113_14765
MTUEJ114_11415
MTXM943_11010
MTULTBHG_02085
MTUTHKBT1_2248(cysS1)
MTUUHKBT2_2250(cysS1)
MTQHKBS1_2254(cysS1)
MBOBQ2027_MB2154C(mshc)
MBBBCG_2147c(cysS2)
MBTJTY_2141(cysS2)
MBMBCGMEX_2133c(cysS2)
MBKK60_022110
MBXBCGT_1951
MAFMAF_21420(cysS2)
MMICRN08_2361
MCEMCAN_21541(cysS2)
MCQBN44_50059(cysS)
MCVBN43_31347(cysS)
MCXBN42_40042(cysS)
MCZBN45_50451(cysS)
MLEML1302(cysS2)
MLBMLBr01302(cysS2)
MPAMAP_1876c(cysS2)
MAOMAP4_1953
MAVIRC58_09755
MAVURE97_09760
MAVMAV_2361(cysS)
MITOCO_23640
MIAOCU_23520
MIDMIP_03257
MYOOEM_22060
MCHIAN480_11905
MIROCQ_22160
MMALCKJ54_10685
MLPMLM_2236
MMANMMAN_16200(mshC)
MSAMycsm_03809
MULMUL_2360(mshC)
MMCMmcs_3153
MKMMkms_3215
MJLMjls_3165
MMIMMAR_3110(mshC)
MMAEMMARE11_30320(mshC)
MMMW7S_11410
MLIMULP_03371(mshC)
MKNMKAN_02345
MYVG155_17845
MYEAB431_18405
MGOAFA91_19155
MHADB586_10540
MDXBTO20_13850
MSHGMSG_03006(mshC)
MFJMFLOJ_02080(mshC)
MSTOMSTO_02740(mshC)
MSIMMSIM_46870(mshC)
MSAKMSAS_10650(mshC)
MKUI2456_15270
MGROFZ046_21870
MXEMYXE_22970(mshC)
MNVMNVI_43580(mshC)
MPAGC0J29_17655
MNMMNVM_00970(mshC)
MGORH0P51_16610
MCOOMCOO_11380(mshC)
MBAIMB901379_02881(mshC)
MSEOMSEO_18160(mshC)
MPSEMPSD_32180(mshC)
MSHOMSHO_45680(mshC)
MHEKJMUB5695_02230(mshC)
MGAUMGALJ_14100(mshC)
MLJMLAC_21310(mshC)
MBRDMBRA_36880(mshC)
MSHJMSHI_11390(mshC)
MKRMKOR_06390(mshC)
MDFK0O62_14330(mshC)
MMAMK3U93_13990(mshC)
MHOLK3U96_11385(mshC)
MHERK3U94_10025(mshC)
MSENK3U95_15230(mshC)
MPAEK0O64_17755(mshC)
MSPGF6B93_13290
MOTLTS72_08815(mshC)
MLMMLPF_1846(mshC)
MVMMJO54_10115(mshC)
MRFMJO55_15960(mshC)
MPAAMKK62_11015(mshC)
MCROMI149_18595(mshC)
MSMMSMEG_4189(cysS)
MSGMSMEI_4091(cysS2)
MSBLJ00_20770
MSNLI99_20775
MSHLI98_20780
MVAMvan_3478
MGIMflv_3049
MSPMspyr1_23640
MCBMycch_3131
MNED174_14110
MYNMyAD_13865
MFTXA26_36370(mshC)
MPHLMPHLCCUG_03253(mshC)
MVQMYVA_3402(cysS1)
MLLB1R94_11530
MRHMycrhN_5129
MTHN4412656_01910(mshC)
MHASMHAS_01577(mshC)
MDUMDUV_09380(mshC)
MCHTMCHIJ_34980(mshC)
MDRMDOR_23330(mshC)
MAUUNCTC10437_03369(mshC)
MMAGMMAD_33800(mshC)
MMORMMOR_36240(mshC)
MFXMFAL_11990(mshC)
MAICMAIC_32490(mshC)
MIJMINS_30510(mshC)
MALVMALV_03630(mshC)
MTYMTOK_53970(mshC)
MPSCMPSYJ_32140(mshC)
MARZMARA_05810(mshC)
MGADMGAD_10700(mshC)
MHEVMHEL_57800(mshC)
MSARMSAR_37340(mshC)
MANYMANY_17490(mshC)
MAUBMAUB_52910(mshC)
MPOFMPOR_36750(mshC)
MPHUMPHO_16650(mshC)
MMUCC1S78_010120
MMATMMAGJ_71410(mshC)
MBOKMBOE_37710(mshC)
MFGK6L26_14120(mshC)
MSEIMSEDJ_45890(mshC)
MFLVNCTC10271_02066(mshC)
MCEEMCEL_04990(mshC)
MABMAB_2116
MMVMYCMA_1106
MABBMASS_2039
MABLMMASJCM_2065
MCHEBB28_10590
MIZBAB75_11340
MSTEMSTE_02046(mshC)
MSAOMYCSP_08980
MSALDSM43276_01828(mshC)
MJDJDM601_1772(mshC)
MTER4434518_01718(mshC)
MMINMMIN_33980(mshC)
MHIBMHIB_12110(mshC)
ASDAS9A_1960(mshC)
MPAKMIU77_07475(mshC)
CGLCgl1514(Cgl1514)
CGBcg1709(cysS2)
CGUWA5_1457(CysS)
CGTcgR_1574
CGSC624_08375
CGGC629_08385
CGMcgp_1709(mshC)
CGJAR0_08110
CGQCGLAR1_07975
CGXSB89_07810
CEFCE1639(cysS)
CDIDIP1261(cysS2)
CDPCD241_1191(cysS2)
CDHCDB402_1170(cysS2)
CDTCDHC01_1190(cysS2)
CDECDHC02_1169(cysS2)
CDRCDHC03_1164(cysS2)
CDACDHC04_1174(cysS2)
CDZCD31A_1272(cysS2)
CDBCDBH8_1239(cysS2)
CDSCDC7B_1255(cysS2)
CDDCDCE8392_1162(cysS2)
CDWCDPW8_1240(cysS2)
CDVCDVA01_1131(cysS2)
CDIPERS451417_01261(cysS2)
CJKjk0368(cysS2) jk0956(cysS1)
CURcu0281 cu1032
CUACU7111_1014(mshC)
CARcauri_1250(mshC)
CKPckrop_0920(mshC)
CPUCPFRC_05295(mshC)
CPLCp3995_1074(mshC)
CPGCP316_05445(mshC)
CPPCpP54B96_1068(mshC)
CPKCP1002_07850(mshC)
CPQCPC231_05300(mshC)
CPXCPI19_06220(mshC)
CPZCpPAT10_1048(mshC)
CORCp267_1100(mshC)
COPCP31_05675(mshC)
CODCp106_1031(mshC)
COSCp4202_1041(mshC)
COICPCIP5297_05465(mshC)
COECP258_05460(mshC)
COUCP162_05830(mshC)
CPSECPTA_01622
CPSUCPTB_02141
CPSFCPTC_01613
CRDCRES_1038(mshC)
CULCULC22_01124(mshC)
CUCCULC809_01109(mshC)
CUECULC0102_1233(cysS)
CUNCul210932_1165(mshC)
CUSCulFRC11_1133(mshC)
CUQCul210931_1115(mshC)
CUZCul05146_1189(mshC)
CUJCUL131002_1147c(mshC)
CVACVAR_1445(mshC)
CHNA605_07425
CCNH924_06935
CTERA606_05610
CMDB841_06875
CAZCARG_04870
CFNCFAL_05375
CCGCCASEI_07275
CVTB843_07135
CGYCGLY_08655(mshC2)
CAXCATYP_05200
CIICIMIT_06450
CUVCUREI_06185
COADR71_50(mshC)
CDOCDOO_07385
CHMB842_06785
CSXCSING_06315 CSING_06890(mshC)
CMQB840_06340(mshC)
CKUUL82_05260(mshC)
CCJUL81_06070(mshC)
CMVCMUST_08100(mshC)
CEICEPID_06495(mshC)
CTEDCTEST_06690(mshC)
CUTCUTER_05510(mshC)
CLWCLAC_06420
CDXCDES_07295(mshC)
CSPWM42_0105(mshC)
CSTACSTAT_06590
CCJZccrud_07370
CFKCFRA_05760
CPHOCPHO_06025
CFCCFLV_06410
CGVCGLAU_06465(mshC)
CSTRCBE89_07260
CAQUCAQU_06410
CSPHCSPHI_06640
CAMGCAMM_06785
CMINNCTC10288_01274(mshC)
CPEGCPELA_05510(mshC)
CXEFOB82_12335(mshC)
CEECENDO_05835(mshC)
CSANE3227_09300(mshC)
CGKCGERO_05625(mshC)
CRFFRC0190_01236
CRLNCTC7448_01926(CysS)
CCHOCCHOA_05890(mshC)
CPRECsp1_14170(mshC)
CPSOCPPEL_05710(mshC)
CSURN24_1606(cysS)
CCYSSAMEA4530656_1085(cysS2)
CMATHBA49_00360(mshC)
CYZC3B44_05605(mshC)
CKFI6I12_06655(mshC)
CANSGP473_04330(mshC)
CLIAC3E79_05615(mshC)
CPRPI6I69_11000(mshC)
CAMCI6I65_02650(mshC)
CGLUI6J20_03620(mshC) I6J20_08460(mshC)
CUOCUROG_04860(mshC)
CLIZG7Y31_05915(mshC)
CSILCBE74_06320
CTUBI6I74_11155(mshC)
CLUJIAU68_05995(mshC)
CQNG7Y29_05490(mshC)
CKWCKALI_05760(mshC)
CCOECETAM_06765(mshC)
COKCOCCU_07455(mshC)
CZOIAU67_04340(mshC)
CCYCSCMU_20620(mshC)
CORYFQV43_05160(mshC)
CMFGWO64_006130(mshC)
CWKIA203_06590(mshC)
CUWLH390_05870(mshC)
CPOYGP475_05960(mshC)
BFVC628_08310
NFANFA_29340(mshC)
NFRERS450000_01160(mshC)
NCYNOCYR_2775(cysS)
NBRO3I_020965
NNONONO_c37250(mshC)
NSLBOX37_16095
NSRNS506_04748(mshC)
NTPCRH09_19110(mshC)
NOZDMB37_01595(mshC)
NODFOH10_12980(mshC)
NAHF5544_22350(mshC)
NADNCTC11293_04018(mshC)
NWLNWFMUON74_33090(mshC)
NIEKV110_21730(mshC)
NTCKHQ06_23545(mshC)
NHUH0264_23835(mshC)
NYALTV02_11300(mshC)
NGPLTT66_33500(mshC)
RHARHA1_ro00877
RERRER_31960(mshC)
REYO5Y_14690
REBXU06_14915
RQIC1M55_15935(mshC)
ROPROP_06130(mshC)
ROAPd630_LPD04960
REQREQ_22990(mshC)
RPYY013_02985
RBYCEJ39_13660(mshC)
RHBNY08_1030
RAVAAT18_13580
RFAA3L23_04280(mshC)
RHSA3Q41_03986(mshC)
RHWBFN03_08490
RRZCS378_03350(mshC)
RHUA3Q40_01708(mshC)
RHQIM25_16935
RHODAOT96_26125
RRT4535765_02337(mshC)
RCRNCTC10994_00506(mshC)
RTMG4H71_21950(mshC)
RKOJWS14_04590(mshC)
RGOKYT97_04675(mshC)
ROZCBI38_13440
GBRGbro_2442
GPOGPOL_c23790(mshC)
GORKTR9_2351
GOQACH46_10420
GTABCM27_12530
GOCCXX93_12580(mshC)
GITC6V83_11530(mshC)
GRUGCWB2_13135(mshC)
GOMD7316_00983(mshC)
GAVC5O27_14950(mshC)
GODGKZ92_11900(mshC)
GAMGII34_11890(mshC)
GPDGII33_11175(mshC)
GJIH1R19_11725(mshC)
GOILK459_21580(mshC)
GHNMVF96_11940(mshC)
GAMIIHQ52_15635(mshC)
SPINKV203_09790(mshC)
TPRTpau_2140
TSMASU32_11680
TPULTPB0596_24440(mshC)
SRTSrot_1222
DTMBJL86_1644
DITC3V38_13760(mshC)
DIZCT688_07945(mshC)
DPCA6048_08200
DLUA6035_07790
CBQAL705_00170
TOYFO059_08695(mshC)
SCOSCO1663(cysS)
SALBXNR_5164
SMASAVERM_6647(mshC)
SGRSGR_5840(cysS2)
SGBWQO_06085
SCBSCAB_73151(cysS2)
SSXSACTE_1098
SVLStrvi_6678
SHYSHJG_3103
SHOSHJGH_2867
SRCM271_38390
SMALSMALA_1465
SSOII1A49_10880
SCTSCAT_5134(cysS)
SCYSCATT_51280
SFASfla_5170
SBHSBI_08453(cysS2)
SVESVEN_1258
SDVBN159_6915(mshC)
SALSSLNWT_6236
STRPF750_1464(mshC)
SFISFUL_1182
SCIB446_08590
SALUDC74_2143
SALLSAZ_11290
SLVSLIV_29430(mshC)
SGUSGLAU_06905(mshC)
SVTSVTN_07760
STREGZL_06994
SCWTU94_06995
SLDT261_6564
SLCSL103_11145
SXISXIM_04930
STRMM444_08655
STRCAA958_04125
SAMBSAM23877_1720(mshC)
SPRISPRI_5889
SCZABE83_29740
SCXAS200_35140
SRWTUE45_02094(mshC_2)
STRFASR50_07950
SLEsle_54540(sle_54540)
SRNA4G23_00897(mshC)
SPAVSpa2297_06465
STRTA8713_05930
SCLFBB341_23530
SGSAVL59_34935
STSIA4E84_08295
SKYD0C37_27810(mshC)
SALWCP975_06560
SGMGCM10017557_66480(mshC)
SCADDN051_30320
SLSSLINC_1891
SNRSNOUR_32045(mshC)
SPLULK06_005125
STRDNI25_30875
SNWBBN63_28220
SAUOBV401_11200
SSIAA7J05_28715
SVUB1H20_05270
SPUNBFF78_33200
SGVB1H19_10275
SLAUSLA_1199
SALFSMD44_01725
SALJSMD11_5351
SLXSLAV_29190(mshC)
STROSTRMOE7_08985
SFKKY5_1496c
SNZDC008_06370
SGEDWG14_06800(mshC_1)
SRJSRO_5805
SLKSLUN_07790(mshC)
SDXC4B68_32345
SGDELQ87_31345
SQZFQU76_05085
SCYAEJ357_09370
SASTCD934_27385
SNQCP978_07900
STIRDDW44_02350
SKACP970_35210
SGZC0216_21720
SVNCP980_26435
SNKCP967_28085
SHAWCEB94_08720(mshC)
SRKFGW37_06820
SFICEIZ62_26930
SGALCP966_06810(mshC)
SSPODDQ41_01815
SVRCP971_26425
SPADDVK44_04260
SFYGFH48_32030(mshC)
SAQUEJC51_11115
SGFHEP81_06112(mshC)
SCAVCVT27_04915
SSEOD0Z67_05250
SBYH7H31_04970
SRIMCP984_33090
SSUBCP968_26280
SPHVF9278_08030
SCINCP977_07285
SFUGCNQ36_07005(mshC)
SPACB1H29_29250
STSUB7R87_05085
SCHACP983_34670
SGXH4W23_08220
SCOECP976_09405(mshC)
SBATG4Z16_28645
SSPBCP982_09730(mshC)
SNFJYK04_02319(mshC_1)
SPLACP981_08100(mshC)
SBROGQF42_11000
STUIGCM10017668_12400(mshC)
SATAC5746_08855
SCHFIPT68_07390
SHUNDWB77_06080(mshC_1)
SHARHUT13_03200
SCYGS1361_09170(mshC)
SFEUIM697_14230
SLIAHA039_27795
SDWK7C20_07200(mshC)
SVDCP969_09300(mshC)
SCALI6J39_05440
SAUHSU9_006135(mshC)
SFBCP974_04675
SMOBJ7W19_06070(mshC)
SPRACP972_07430(mshC)
SPEUCGZ69_06820
SROIIAG44_32110(mshC)
SXNIAG42_28700
SGJIAG43_05670
SHKJ2N69_06505(mshC)
SANUK7396_28615(mshC)
STRYEQG64_04920
SDDD9753_28545(mshC)
SACTDMT42_07355
SMAOCAG99_24840
SGOBtest1122_01400(mshC)
SINEKI385_10485(mshC)
SLFJEQ17_37020(mshC)
SDECL3078_09530(mshC)
KSKKSE_66390(mshC)
KABB7C62_04985
KAUB6264_20980
KITCFP65_1340
STRIC7M71_027680
YIALO772_27540(mshC)
LXLKDY119_01677(mshC)
PSICJ4E96_07480
CMICMM_1694(cysS2)
CMSCMS1669(cysS)
CMCCMN_01673(mshC)
CMHVO01_07700
CCAPAES38_08185
CZHH9X71_08505
MCHNHCR76_07815
RTXTI83_06470
RTCAPU90_10620
RTNA6122_1297
RRYC1O28_05855
RIAC7V51_04380
RFSC1I64_07810
RTEGSU10_07440
CUMNI26_08265
CUBBJK06_17815
CUGC1N91_08400
FRPAX769_12405
CARTPA27867_1750
CRYB7495_08560
CPHYB5808_08865
MYLC3E77_06795
MSPOKXZ72_03020(mshC)
SALCC2138_06035
SALDFVA74_05905
HUMDVJ78_12010
HUWFPZ11_01960
GRYD7I44_15720
PLAPEAO79_14315
LEULeucomu_08505
LTREVS81_01220
LEBG7066_06645
LDNH9L06_02590
LVIG7068_00385
LINSG7067_08535
AGGC1N71_07065
MANTBHD05_11320
HEAHL652_07655
FRNF1C15_02210
GLNF1C58_07115
AGXAGREI_1489(mshC)
SUBTKPL76_10935(mshC)
PSEVUSB125703_01901(mshC)
GSDM3M28_06325(mshC)
ARTArth_2168
ARRARUE_c23240(cysS2)
ARMART_0678
ARLAFL94_08190
AREAL755_11770
AAQAOC05_06935
ARWMB46_05370
ARHAHiyo8_63840
ARYATC04_09710
ARZAUT26_10710
ARUASPU41_15915
ARQBWQ92_21085
ARNCGK93_12595(mshC)
ARXARZXY2_1811(mshC)
ACRYAC20117_18655
ARTHC3B78_10195(mshC)
ARTPE5206_12630(mshC)
AAGINCTC2676_1_01361(mshC)
AJGKKR91_09040(mshC)
ASUNKG104_09475(mshC)
ASUFMNQ99_10580(mshC)
ARIUM93_04300
AAUAAur_2169
PUEFV140_10970(mshC)
PNVJMY29_10290(mshC)
ACHAchl_1911
APNAsphe3_18930
PSULAU252_21645
PSNINIBR502771_14905(mshC)
PSEYGU243_04615(mshC)
AAIAARI_16310(cysS)
GARAOZ07_08390
GCRGcLGCM259_1403(mshC)
GLUF0M17_08205(mshC)
GPRJQN66_08360
RSARSal33209_2044
KRHKRH_13920(mshC)
KPLKPaMU14_06485
KFVAS188_10740
KIIKocCE7_07135
KRSEQG70_09815
KODHBK84_07300
KVRCIB50_0001736(mshC)
MLUMlut_11810
MICKB1A86_00005835
RMURMDY18_10290
RDNHMPREF0733_11956(mshC)
RAJRA11412_1933
RTERIDM49_06450
RAMAIDM48_06295
RKRI6G21_09310
SATKSA2016_2029
NAEBHE16_02885
AULDCC27_003615
PAEYKUF55_09545(mshC)
BCVBcav_2247
BFABfae_16240
BRXBH708_03560
BGGCFK41_08625
BRZCFK38_10830
BSAUDWV08_05610
BRRC1N80_10835
BKIM4486_05405(mshC)
JDEJden_1195
KSEKsed_13890
DNIHX89_07480
DAYFV141_06700
LMOIVV02_16035
YIMJ5M86_07305
ALXLVQ62_12370(mshC)
XCEXcel_1479
XYLET495_03570
XYAET471_13165
IVAIsova_1436
IDOI598_0779(mshC)
CETB8281_12280
CCEUCBR64_19435
SKESked_20970
SANWG7063_07140
CFLCfla_2010
CFICelf_1780
CGACelgi_1846
CELZE5225_07645
CEJGC089_07950
CELHGXP71_05770
CIRALFM56_07970(mshC)
OEKFFI11_012645
PSEIGCE65_06280
ICAIntca_1753
ARSADJ73_12730
JTEASJ30_07950
JLIEXU32_07305
JMEEEW87_007310
TEHGKE56_04590
PHWG7075_06625
PEIH9L10_05830
SERJSGUI_0324
SERWFY030_08030
ORNDV701_02720
ORZFNH13_10975
BLYA2T55_09360
BLINBLSMQ_2091
BRIFDF13_11170
BLUTEW640_03405
BCAUI6G59_12860
DCOSAMEA4475696_1724(mshC)
GEZFE251_06850
GYUFE374_07380
HALTIM660_08795
RHALLQF10_08255(mshC)
RSUALQF12_07355(mshC)
PFRPFREUD_14130(cysS1)
PFRERM25_1334
PACDEGX94_02085
PAUSNCTC13651_02249(mshC)
PPCHMPREF9154_2051(mshC)
ARUBJ5A65_05585
MPHMLP_17040(mshC)
MIKFOE78_16675
MICGGJV80_10680
TFLRPIT_08310
TFABW733_01015 BW733_14760
TESBW730_02915
TEZBKM78_02620
TDFH9L22_07335
TLATLA_TLA_00532(mshC)
RAINRai3103_16040
PRVG7070_14165
BRTJ4N02_09830
NCANoca_2628
NDKI601_3334(mshC_1) I601_4058(mshC_2)
NOYEXE57_01800
NOIFCL41_08395
NOOFE634_10325
NDPE2C04_08995
NSNEXE58_17755
NBEBack2_02160(cysS_1)
NANOG5V58_10885
NMESH9L09_20405
NAROCFH99_12690
NPIG7071_10980 G7071_14965
NAQUENKNEFLB_02420(mshC_1) ENKNEFLB_03748(mshC_2)
NROK8W59_08845(mshC) K8W59_12315
NOQLN652_01860(mshC)
NCQK6T13_04750 K6T13_08975(mshC)
NPCKUV85_04960(mshC) KUV85_06590
NPSKRR39_08465(mshC)
PSIMKR76_13260
AERAERYTH_09025
AEZC3E78_09230
AEBC6I20_06855
AEFGEV26_08635
MGGMPLG2_1802(mshC)
MUZH4N58_10420
KFLKfla_3804
KQIF1D05_02930
TFUTfu_1832
THAONI17_011180(mshC)
TALXFOF52_08720(mshC)
NDANdas_1544
NALB005_4133(mshC)
NGVCDO52_17390
NEXNE857_14165(mshC)
STRREKD16_14115(mshC)
SAIUJ4H86_01205
TCUTcur_0549 Tcur_2287
ACTWF7P10_00750
AGRAAGRA3207_000515
SROSros_5930
NOABKM31_06205
NOWGBF35_32330
NCXNocox_26285(mshC)
NGNLCN96_35405(mshC)
TBITbis_1932
FRAFrancci3_2642
FREFranean1_4892
FRIFraEuI1c_3764
FALFRAAL2858(cysS2)
FSYFsymDg_2272
ACEAcel_1172
NMLNamu_2573 Namu_2780
NAKEH165_07205
GOBGobs_2219 Gobs_2668
BSDBLASA_2691(cysS2)
MMARMODMU_2589(cysS)
KRAKrad_1836
SENSACE_2226(cysS2)
SACGFDZ84_02050
SVISvir_22240 Svir_22970
SACCEYD13_12375(mshC1) EYD13_12820(mshC2)
AMDAMED_4930(cysS)
AMNRAM_25095
AMMAMES_4871(cysS)
AMZB737_4871(cysS)
AOIAORI_3794(cysS)
AJAAJAP_20185(mshC)
AMQAMETH_3568(cysS)
AMYCCU254_18120(mshC)
AMYBBKN51_11450
AABA4R43_10960
AMYYYIM_27465(mshC)
AORISD37_19470
AACDLWP59_15130(mshC)
PDXPsed_3330
PSEAWY02_02660 WY02_17645
PSEEFRP1_12340
PSEHXF36_10280
PSEQAD006_18630
PECQAD017_26470
PHHAFB00_26255
PAUTPdca_33300(cysS_1)
PBROHOP40_01085 HOP40_24850
APRECNX65_11215
AMIAmir_2201
SESPBN6_31410(mshC)
SSYIEKG83_34340
KALKALB_3015
KPHYAOZ06_20310
LEDBBK82_45445
AHMTL08_13190
ACTIUA75_14180
ACADUA74_14095
AHGAHOG_13260(mshC)
ACTAC1701_22465
ALOCRK57420
PMADBAY61_17045 BAY61_17650
SACEGIY23_09785
STPStrop_2168
SAQSare_2322
MAUMicau_2918
MILML5_5478
MICBMicB006_6032
MTUACSH63_10490
MICHFJK98_19510
MTEMGCE86_06865
MCABHXZ27_17670
MSAGGCM10017556_49050(cysS)
VMAVAB18032_22945
MCRAID554_00870
ASEACPL_5266(mshC)
AMSAMIS_53910(mshC)
ACTNL083_5113(cysS)
AFSAFR_26630
ACTSACWT_5136
AIHAiant_10450(cysS_1)
ACTRAsp14428_78950(mshC_2)
PLKCIK06_13890
PLABC6361_03060
PLATC6W10_18570
PFLAPflav_019260
PSUUPsuf_077890(cysS)
VERHUT12_19775
ATLAthai_13820(cysS_2) Athai_31580(mshC)
ASERAsera_43170(mshC)
PRYPrubr_68480(cysS_2)
CATICS0771_69090(cysS)
DVCDvina_37155
NHYJQS43_13525
CCAZCOUCH_16815 COUCH_18220(mshC)
CAICaci_5399
SNASnas_4502
NAVJQS30_07435
GLYK3N28_19355(mshC)
TBWNCTC13354_00048(mshC)
ASGFB03_01895
ACTTDDD63_05780
FSLEJO69_01710
FLHEJ997_02785
AEYCDG81_14280
PLANA1s21148_03600
PLAKA1s21155_03415
PLIMPHILAsVB114_03465
PSUFA1sIA56_03320
PVSA1sIA79_03235
PVNA7sIIA15_03620
ABAMB1s21122_03285
NHIB1s21160_03160
NABB1sIIB91_02980
EKEEK0264_18505
JTLM6D93_09965(mshC)
ABAIIMCC26256_11974
AFOAfer_1230
AYMYM304_19700(mshC)
ATQGH723_08475
AQZKSP35_02995
IAMHC251_13965
ERZER308_04690
EUZDVS28_a1275
RRSRoseRS_3331
RCARcas_4315
CAUCaur_0747
CHLChy400_0810
CAGCagg_2860
HAUHaur_4263
TROtrd_1909(cysS)
STISthe_3518
KBSEPA93_27875
TTRTter_1206
 » show all
Reference
1  [PMID:17848100]
  Authors
Fan F, Luxenburger A, Painter GF, Blanchard JS
  Title
Steady-state and pre-steady-state kinetic analysis of Mycobacterium smegmatis cysteine ligase (MshC).
  Journal
Biochemistry 46:11421-9 (2007)
DOI:10.1021/bi7011492
  Sequence
Reference
2  [PMID:16908186]
  Authors
Gutierrez-Lugo MT, Newton GL, Fahey RC, Bewley CA
  Title
Cloning, expression and rapid purification of active recombinant mycothiol ligase as B1 immunoglobulin binding domain of streptococcal protein G, glutathione-S-transferase and maltose binding protein fusion proteins in Mycobacterium smegmatis.
  Journal
Protein Expr Purif 50:128-36 (2006)
DOI:10.1016/j.pep.2006.07.005
Reference
3  [PMID:19053270]
  Authors
Tremblay LW, Fan F, Vetting MW, Blanchard JS
  Title
The 1.6 A crystal structure of Mycobacterium smegmatis MshC: the penultimate enzyme in the mycothiol biosynthetic pathway.
  Journal
Biochemistry 47:13326-35 (2008)
DOI:10.1021/bi801708f
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 6.3.1.13
IUBMB Enzyme Nomenclature: 6.3.1.13
ExPASy - ENZYME nomenclature database: 6.3.1.13
BRENDA, the Enzyme Database: 6.3.1.13

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