KEGG   ENZYME: 6.3.1.19
Entry
EC 6.3.1.19                 Enzyme                                 
Name
prokaryotic ubiquitin-like protein ligase;
PafA (ambiguous);
Pup ligase;
proteasome accessory factor A
Class
Ligases;
Forming carbon-nitrogen bonds;
Acid-D-ammonia (or amine) ligases (amide synthases)
Sysname
[prokaryotic ubiquitin-like protein]:[protein]-L-lysine
Reaction(IUBMB)
ATP + [prokaryotic ubiquitin-like protein]-L-glutamate + [protein]-L-lysine = ADP + phosphate + N6-([prokaryotic ubiquitin-like protein]-gamma-L-glutamyl)-[protein]-L-lysine [RN:R11207]
Reaction(KEGG)
R11207
Substrate
ATP [CPD:C00002];
[prokaryotic ubiquitin-like protein]-L-glutamate [CPD:C21177];
[protein]-L-lysine [CPD:C02188]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
N6-([prokaryotic ubiquitin-like protein]-gamma-L-glutamyl)-[protein]-L-lysine [CPD:C21178]
Comment
The enzyme has been characterized from the bacteria Mycobacterium tuberculosis and Corynebacterium glutamicum. It catalyses the ligation of the prokaryotic ubiquitin-like protein (Pup) to a target protein by forming a bond between an epsilon-amino group of a lysine residue of the target protein and the gamma-carboxylate of the C-terminal glutamate of the ubiquitin-like protein (Pup). The attachment of Pup, also known as Pupylation, marks proteins for proteasomal degradation.
History
EC 6.3.1.19 created 2015
Orthology
K13571  proteasome accessory factor A
Genes
MTURv2097c(pafA)
MTVRVBD_2097c
MTCMT2158
MRAMRA_2112
MTFTBFG_12132
MTBTBMG_01885
MTKTBSG_01897
MTZTBXG_001869
MTGMRGA327_12905
MTECCDC5079_1939
MTURCFBS_2220
MTLCCDC5180_1916
MTOMTCTRI2_2136
MTDUDA_2097c
MTNERDMAN_2315
MTJJ112_11230
MTUBMT7199_2128
MTUCJ113_14520
MTUEJ114_11240
MTXM943_10865
MTULTBHG_02055
MTUTHKBT1_2214
MTUUHKBT2_2215
MTQHKBS1_2219
MBOBQ2027_MB2124C(pafa)
MBBBCG_2117c
MBTJTY_2111
MBMBCGMEX_2101c(pafA)
MBKK60_021790
MBXBCGT_1919
MAFMAF_21110
MMICRN08_2325
MCEMCAN_21241
MCQBN44_50022
MCVBN43_31312
MCXBN42_40005
MCZBN45_50418
MLEML1328
MLBMLBr01328
MPAMAP_1833c
MAOMAP4_1995
MAVIRC58_09955
MAVURE97_09965
MAVMAV_2406
MITOCO_24090
MIAOCU_23970
MIDMIP_03326
MYOOEM_22520
MCHIAN480_12125
MIROCQ_22620
MMALCKJ54_10915(pafA)
MLPMLM_2188
MMANMMAN_15600(pafA)
MSAMycsm_03736
MULMUL_2329
MMCMmcs_2467
MKMMkms_2512
MJLMjls_2504
MMIMMAR_3083
MMAEMMARE11_30050
MMMW7S_11615
MLIMULP_02722(pafA1)
MKNMKAN_02160
MYVG155_17635
MYEAB431_14660
MGOAFA91_20610
MHADB586_10675
MDXBTO20_14070
MSHGMSG_02973(pafA)
MFJMFLOJ_02440(pafA)
MSTOMSTO_03140(pafA)
MSIMMSIM_47220(pafA)
MSAKMSAS_10440(pafA)
MKUI2456_15155(pafA)
MGROFZ046_21720(pafA)
MXEMYXE_23310(pafA)
MNVMNVI_43350(pafA)
MPAGC0J29_17515(pafA)
MNMMNVM_39310(pafA)
MGORH0P51_16515(pafA)
MCOOMCOO_11160(pafA)
MBAIMB901379_02855(pafA)
MSEOMSEO_17840(pafA)
MPSEMPSD_31980(pafA)
MSHOMSHO_45370(pafA)
MHEKJMUB5695_02258(pafA)
MGAUMGALJ_14420(pafA)
MLJMLAC_20880(pafA)
MBRDMBRA_37150(pafA)
MSHJMSHI_11670(pafA)
MKRMKOR_06590(pafA)
MDFK0O62_14490(pafA)
MMAMK3U93_13885(pafA)
MHOLK3U96_11530(pafA)
MHERK3U94_11975(pafA)
MSENK3U95_15005(pafA)
MPAEK0O64_14035(pafA)
MSPGF6B93_13185(pafA)
MOTLTS72_08970(pafA)
MLMMLPF_3311(pafA)
MVMMJO54_11925(pafA)
MRFMJO55_15730(pafA)
MPAAMKK62_11130(pafA)
MCROMI149_14845(pafA)
MSMMSMEG_3890
MSGMSMEI_3800(pafA)
MSBLJ00_19325
MSNLI99_19330
MSHLI98_19335
MVAMvan_3445
MGIMflv_3089
MSPMspyr1_24050
MCBMycch_3075
MNED174_14315
MYNMyAD_14060
MFTXA26_35950
MPHLMPHLCCUG_02715(pafA)
MVQMYVA_3356
MLLB1R94_11720
MRHMycrhN_5100
MTHN4412656_01940(pafA)
MHASMHAS_01604(pafA)
MDUMDUV_10580(pafA)
MCHTMCHIJ_40140(pafA)
MDRMDOR_17290(pafA)
MAUUNCTC10437_03321(pafA)
MMAGMMAD_33250(pafA)
MMORMMOR_35830(pafA)
MFXMFAL_11700(pafA)
MAICMAIC_25600(pafA)
MIJMINS_30100(pafA)
MALVMALV_03970(pafA)
MTYMTOK_53490(pafA)
MPSCMPSYJ_32640(pafA)
MARZMARA_06180(pafA)
MGADMGAD_10380(pafA)
MHEVMHEL_57440(pafA)
MSARMSAR_42250(pafA)
MANYMANY_17160(pafA)
MAUBMAUB_53540(pafA)
MPOFMPOR_36190(pafA)
MPHUMPHO_15920(pafA)
MMUCC1S78_010430(pafA)
MMATMMAGJ_70880(pafA)
MBOKMBOE_38240(pafA)
MFGK6L26_14330(pafA)
MSEIMSEDJ_45570(pafA)
MFLVNCTC10271_02102(pafA)
MCEEMCEL_05300(pafA)
MABMAB_2183
MMVMYCMA_1156
MABBMASS_2110
MABLMMASJCM_2134
MCHEBB28_10985
MIZBAB75_11700
MSTEMSTE_02123(pafA)
MSAOMYCSP_09360
MSALDSM43276_01897(pafA)
MJDJDM601_2120
MTER4434518_02041(pafA)
MMINMMIN_37270(pafA)
MHIBMHIB_15770(pafA)
ASDAS9A_2012
MPAKMIU77_07570(pafA)
CGLCgl1494(Cgl1494)
CGBcg1688
CGUWA5_1437
CGTcgR_1554
CGSC624_08270
CGGC629_08280
CGMcgp_1688(pafA2)
CGJAR0_08005
CGQCGLAR1_07870
CGXSB89_07710
CEFCE1623
CDIDIP1245
CDPCD241_1175(pafA2)
CDHCDB402_1154(pafA2)
CDTCDHC01_1174(pafA2)
CDECDHC02_1153(pafA2)
CDRCDHC03_1148(pafA2)
CDACDHC04_1158(pafA2)
CDZCD31A_1256(pafA2)
CDBCDBH8_1223(pafA2)
CDSCDC7B_1239(pafA2)
CDDCDCE8392_1146(pafA2)
CDWCDPW8_1224(pafA2)
CDVCDVA01_1115(pafA2)
CDIPERS451417_01245(pafA2)
CJKjk0945
CURcu1043
CUACU7111_1025(pafA2)
CARcauri_1264
CKPckrop_0910(pafA2)
CPUCPFRC_05215(pafA)
CPLCp3995_1056(pafA)
CPGCP316_05365(pafA)
CPPCpP54B96_1052(pafA)
CPKCP1002_07930(pafA)
CPQCPC231_05220(pafA)
CPXCPI19_06300(pafA)
CPZCpPAT10_1032(pafA)
CORCp267_1081(pafA)
COPCP31_05595(pafA)
CODCp106_1015(pafA)
COSCp4202_1025(pafA)
COICPCIP5297_05385(pafA)
COECP258_05380(pafA)
COUCP162_05910(pafA)
CPSECPTA_01604
CPSUCPTB_02159
CPSFCPTC_01595
CRDCRES_1023(pafA2)
CULCULC22_01108
CUCCULC809_01093(pafA2)
CUECULC0102_1215
CUNCul210932_1149(pafA)
CUSCulFRC11_1117(pafA)
CUQCul210931_1099(pafA)
CUZCul05146_1173(pafA)
CUJCUL131002_1131c(pafA)
CVACVAR_1421
CHNA605_07335
CCNH924_06855
CTERA606_05520
CMDB841_06805
CAZCARG_04755
CFNCFAL_05320
CCGCCASEI_07210
CVTB843_07040
CGYCGLY_08740(pafA)
CIICIMIT_06335
CUVCUREI_06090
COADR71_64(pafA)
CDOCDOO_07310
CHMB842_06855
CSXCSING_06960(pafA)
CMQB840_06270(pafA)
CKUUL82_05180(pafA)
CCJUL81_05990(pafA)
CMVCMUST_08010(pafA)
CEICEPID_06380(pafA)
CTEDCTEST_06610(pafA)
CUTCUTER_05430(pafA)
CLWCLAC_06485
CDXCDES_07215(pafA)
CSPWM42_0091(pafA)
CSTACSTAT_06520
CCJZccrud_07250
CFKCFRA_05855
CPHOCPHO_06095
CFCCFLV_06340
CGVCGLAU_06375(pafA)
CSTRCBE89_07190
CAQUCAQU_06335
CSPHCSPHI_06710
CAMGCAMM_06720
CMINNCTC10288_01260(pafA)
CPEGCPELA_05585(pafA)
CXEFOB82_12430(pafA)
CEECENDO_05765(pafA)
CSANE3227_09380(pafA)
CGKCGERO_05550(pafA)
CRFFRC0190_01220
CRLNCTC7448_01910(pafA)
CCHOCCHOA_05830(pafA)
CPRECsp1_14320(pafA)
CPSOCPPEL_05785(pafA)
CSURN24_1585
CCYSSAMEA4530656_1099(pafA)
CYZC3B44_05670(pafA)
CKFI6I12_06725(pafA)
CANSGP473_04260(pafA)
CLIAC3E79_05515(pafA)
CPRPI6I69_10945(pafA)
CAMCI6I65_02720(pafA)
CGLUI6J20_03710(pafA)
CUOCUROG_04785(pafA)
CLIZG7Y31_05845(pafA)
CSILCBE74_06240
CTUBI6I74_11085(pafA)
CLUJIAU68_05920(pafA)
CQNG7Y29_05400(pafA)
CKWCKALI_05630(pafA)
CCOECETAM_06665(pafA)
COKCOCCU_07315(pafA)
CZOIAU67_04240(pafA)
CCYCSCMU_20730(pafA)
CORYFQV43_05090(pafA)
CMFGWO64_006195(pafA)
CUWLH390_05800(pafA)
CPOYGP475_05880(pafA)
BFVC628_08200
NFANFA_31700
NFRERS450000_00902(pafA)
NCYNOCYR_3335(pafA)
NBRO3I_026795
NNONONO_c34100(pafA)
NSLBOX37_11540
NSRNS506_05082(pafA)
NTPCRH09_17345(pafA)
NODFOH10_12430(pafA)
NAHF5544_26410(pafA)
NADNCTC11293_04454(pafA)
NWLNWFMUON74_32200(pafA)
NIEKV110_25975(pafA)
NTCKHQ06_22310(pafA)
NHUH0264_20860(pafA)
NYALTV02_13450(pafA)
NGPLTT66_27200(pafA)
RHARHA1_ro00841
RERRER_31710(pafA)
REYO5Y_14565
REBXU06_14785
RQIC1M55_15805(pafA)
ROPROP_05790(pafA)
ROAPd630_LPD04924
REQREQ_23310
RPYY013_04110
RBYCEJ39_14805(pafA)
RHBNY08_1006
RAVAAT18_13810
RFAA3L23_04257(pafA)
RHSA3Q41_04009(pafA)
RHWBFN03_08345
RRZCS378_03515(pafA)
RHUA3Q40_01727(pafA)
RHQIM25_17995
RHODAOT96_26000
RRT4535765_02618(pafA)
RCRNCTC10994_00434(pafA)
RTMG4H71_21830(pafA)
RKOJWS14_04415(pafA)
RGOKYT97_04525(pafA)
ROZCBI38_13580
GBRGbro_2465
GPOGPOL_c23990(pafA)
GORKTR9_2374
GOQACH46_10495
GTABCM27_12660
GOCCXX93_12500(pafA)
GITC6V83_11435(pafA)
GRUGCWB2_13010(pafA)
GOMD7316_01005(pafA)
GAVC5O27_15080(pafA)
GODGKZ92_11770(pafA)
GAMGII34_11770(pafA)
GPDGII33_11065(pafA)
GJIH1R19_11850(pafA)
GOILK459_21485(pafA)
GHNMVF96_12065(pafA)
GAMIIHQ52_15505(pafA)
SPINKV203_09690(pafA)
TPRTpau_2166
TSMASU32_11810
TPULTPB0596_24140(pafA)
SRTSrot_1603
DTMBJL86_1630
DITC3V38_13700(pafA)
DIZCT688_07875(pafA)
DPCA6048_08130
DLUA6035_07725
CBQAL705_00125
TOYFO059_08630(pafA)
SCOSCO1640(SCI41.23c)
SALBXNR_5187
SMASAVERM_6685
SGRSGR_5863
SGBWQO_05965
SCBSCAB_73511
SSXSACTE_1070
SVLStrvi_6646
SHYSHJG_3077
SHOSHJGH_2841
SRCM271_38560
SMALSMALA_1428
SSOII1A49_10700(pafA)
SCTSCAT_5177
SCYSCATT_51690
SFASfla_5196
SBHSBI_08486
SVESVEN_1233
SDVBN159_6943(pafA)
SALSSLNWT_6263
STRPF750_1438(pafA)
SFISFUL_1158
SCIB446_08465
SALUDC74_2110
SALLSAZ_11115
SLVSLIV_29540(pafA)
SGUSGLAU_06775(pafA)
SVTSVTN_07630
STREGZL_07028
SCWTU94_06880
SLDT261_6604
SLCSL103_11310
SXISXIM_04690
STRMM444_08535
STRCAA958_03980
SAMBSAM23877_1695(pafA)
SPRISPRI_5915
SCZABE83_29855
SCXAS200_35270
SRWTUE45_02066(pafA)
STRFASR50_07835
SLEsle_54770(sle_54770)
SRNA4G23_00873(pafA)
SPAVSpa2297_06355
STRTA8713_05815
SCLFBB341_23675
SGSAVL59_34805
STSIA4E84_08175
SKYD0C37_27930(pafA)
SALWCP975_06370(pafA)
SGMGCM10017557_66830(pafA)
SCADDN051_30450(pafA)
SLSSLINC_1856
SNRSNOUR_32210(pafA)
SPLULK06_004995
STRDNI25_30990
SNWBBN63_28360
SAUOBV401_11015
SSIAA7J05_28850
SVUB1H20_05145
SPUNBFF78_33330
SGVB1H19_10135
SLAUSLA_1175
SALFSMD44_01695(pafA)
SALJSMD11_5383(pafA)
SLXSLAV_29310(pafA)
STROSTRMOE7_08815
SFKKY5_1442c
SNZDC008_06240(pafA)
SGEDWG14_06835(pafA)
SRJSRO_5828
SLKSLUN_07650(pafA)
SDXC4B68_32490(pafA)
SGDELQ87_31525(pafA)
SQZFQU76_04960(pafA)
SCYAEJ357_09135(pafA)
SASTCD934_27505(pafA)
SNQCP978_07770(pafA)
STIRDDW44_02230(pafA)
SKACP970_35495(pafA)
SGZC0216_21595(pafA)
SVNCP980_26560(pafA)
SNKCP967_28220(pafA)
SHAWCEB94_08585(pafA)
SRKFGW37_06685(pafA)
SFICEIZ62_27050(pafA)
SGALCP966_06640(pafA)
SSPODDQ41_01690(pafA)
SVRCP971_26515(pafA)
SPADDVK44_04125(pafA)
SFYGFH48_32180(pafA)
SAQUEJC51_10900(pafA)
SGFHEP81_06135(pafA)
SCAVCVT27_04790(pafA)
SSEOD0Z67_05115(pafA)
SBYH7H31_04850(pafA)
SRIMCP984_33300(pafA)
SSUBCP968_26400(pafA)
SPHVF9278_07825(pafA)
SCINCP977_07170(pafA)
SFUGCNQ36_06880(pafA)
SPACB1H29_29370
STSUB7R87_04960
SCHACP983_34825(pafA)
SGXH4W23_08095(pafA)
SCOECP976_09280(pafA)
SBATG4Z16_28765(pafA)
SSPBCP982_09545(pafA)
SNFJYK04_02294(pafA)
SPLACP981_07925(pafA)
SBROGQF42_10865(pafA)
STUIGCM10017668_12150(pafA)
SATAC5746_08695(pafA)
SCHFIPT68_07265(pafA)
SHUNDWB77_06114(pafA)
SHARHUT13_03095(pafA)
SCYGS1361_09045(pafA)
SFEUIM697_14370(pafA)
SLIAHA039_27955(pafA)
SDWK7C20_07025(pafA)
SVDCP969_09175(pafA)
SCALI6J39_05325(pafA)
SAUHSU9_005965(pafA)
SFBCP974_04555(pafA)
SMOBJ7W19_05900(pafA)
SPRACP972_07310(pafA)
SPEUCGZ69_06710(pafA)
SROIIAG44_32310(pafA)
SXNIAG42_28905(pafA)
SGJIAG43_05555(pafA)
SHKJ2N69_06290(pafA)
SANUK7396_28785(pafA)
SDDD9753_28675(pafA)
SACTDMT42_07215(pafA)
SMAOCAG99_24945
SGOBtest1122_01280(pafA)
SINEKI385_10310(pafA)
SLFJEQ17_37225(pafA)
SDECL3078_09325(pafA)
KSKKSE_66650(pafA)
KABB7C62_04860
KAUB6264_21070
KITCFP65_1315
STRIC7M71_027770(pafA)
YIALO772_28310(pafA)
LXLKDY119_01692
PSICJ4E96_07530(pafA)
ARTArth_2178
ARRARUE_c23340
ARMART_0666
ARLAFL94_08230
AREAL755_11820
AAQAOC05_06985
ARWMB46_05420
ARHAHiyo8_63940
ARYATC04_09670
ARZAUT26_10760
ARUASPU41_15965
ARQBWQ92_21035
ARNCGK93_12645(pafA)
ARXARZXY2_1801(pafA)
ACRYAC20117_18705
ARTHC3B78_10245(pafA)
ARTPE5206_12580(pafA)
AJGKKR91_08990(pafA)
ASUNKG104_09425(pafA)
ASUFMNQ99_10530(pafA)
ARIUM93_04355
AAUAAur_2179
PUEFV140_11020(pafA)
PNVJMY29_10340(pafA)
ACHAchl_1921
APNAsphe3_19030
PSULAU252_21595
PSNINIBR502771_14855(pafA)
PSEYGU243_04665(pafA)
AAIAARI_16390
GARAOZ07_08430
GCRGcLGCM259_1411(pafA)
GLUF0M17_08245(pafA)
GPRJQN66_08400(pafA)
RSARSal33209_2034
KRHKRH_13850
KPLKPaMU14_06510
KFVAS188_10780
KIIKocCE7_07100(pafA)
KRSEQG70_09775(pafA)
KODHBK84_07265(pafA)
KVRCIB50_0001743(pafA)
MLUMlut_11920
MICKB1A86_00005885(pafA)
RMURMDY18_10370
RDNHMPREF0733_11951(pafA)
RAJRA11412_1841
RTERIDM49_06415(pafA)
RAMAIDM48_06260(pafA)
RKRI6G21_09280(pafA)
SATKSA2016_2039
NAEBHE16_02845
AULDCC27_003655(pafA)
PAEYKUF55_09495(pafA)
BCVBcav_2237
BFABfae_16170
BRXBH708_03525
BRVCFK39_00595(pafA)
BGGCFK41_08660(pafA)
BRZCFK38_10865(pafA)
BSAUDWV08_05575(pafA)
BRRC1N80_10870(pafA)
BKIM4486_05440(pafA)
DVADAD186_10820
DJJCOP05_05565(pafA)
JDEJden_1206
DNIHX89_07365
DAYFV141_06620(pafA)
LMOIVV02_15885
YIMJ5M86_07405(pafA)
ALXLVQ62_12665(pafA)
XCEXcel_1490
XYLET495_03625(pafA)
XYAET471_13220(pafA)
IVAIsova_1451
IDOI598_0768(pafA)
CETB8281_12335
CCEUCBR64_19365
SKESked_20850
SANWG7063_07205(pafA)
CFLCfla_1999
CFICelf_1794
CGACelgi_1834
CEZCBP52_04180
CELZE5225_07705(pafA)
CEJGC089_08020(pafA)
CELHGXP71_05825(pafA)
CIRALFM56_08040(pafA)
OEKFFI11_012710(pafA)
PSEIGCE65_06340(pafA)
ICAIntca_1774
JTEASJ30_07870
JLIEXU32_07225(pafA)
JMEEEW87_007395(pafA)
TEHGKE56_04690(pafA)
PHWG7075_06515(pafA)
SERJSGUI_0335
SERWFY030_07960(pafA)
ORNDV701_02815(pafA)
ORZFNH13_10860(pafA)
BLYA2T55_09300
BLINBLSMQ_2079
BRIFDF13_11110(pafA)
BLUTEW640_03465(pafA)
BCAUI6G59_12800(pafA)
DCOSAMEA4475696_1703(pafA)
AUSIPK37_17315(pafA)
GEZFE251_07040(pafA)
GYUFE374_07425(pafA)
HALTIM660_08845(pafA)
RHALLQF10_08305(pafA)
RSUALQF12_07405(pafA)
DEMLGT36_005520(pafA)
MPHMLP_17560(pafA)
MIKFOE78_16335(pafA)
MICGGJV80_10350(pafA)
RAINRai3103_15835(pafA)
PRVG7070_17060
BRTJ4N02_07140
NCANoca_2648
NDKI601_3312(pafA)
NOYEXE57_01950(pafA)
NOIFCL41_08465(pafA)
NOOFE634_10425(pafA)
NDPE2C04_09065(pafA)
NSNEXE58_17665(pafA)
NBEBack2_02400(pafA)
NANOG5V58_10980(pafA)
NMESH9L09_20300(pafA)
NAROCFH99_12585(pafA)
NPIG7071_14860(pafA)
NAQUENKNEFLB_02400(pafA)
NROK8W59_08755(pafA)
NOQLN652_01975(pafA)
NCQK6T13_09045(pafA)
NPCKUV85_05055(pafA)
NPSKRR39_08565(pafA)
PSIMKR76_13420
AERAERYTH_08940
AEZC3E78_09335(pafA)
AEBC6I20_06930(pafA)
AEFGEV26_08745(pafA)
MGGMPLG2_1733(pafA)
MUZH4N58_10325(pafA)
KFLKfla_5110
KQIF1D05_08030(pafA)
TFUTfu_1788
THAONI17_011025(pafA)
TALXFOF52_08555(pafA)
NDANdas_1497
NALB005_4102(pafA)
NGVCDO52_13730(pafA)
NEXNE857_13835(pafA)
STRREKD16_11915(pafA)
SAIUJ4H86_01320(pafA)
TCUTcur_2313
ACTWF7P10_00630(pafA)
AGRAAGRA3207_000490(pafA) AGRA3207_003824(pafA)
SROSros_5868
NOABKM31_06475 BKM31_50015
NOWGBF35_32100(pafA)
NCXNocox_26060(pafA)
NGNLCN96_07780(pafA) LCN96_35135(pafA)
TBITbis_1829
FRAFrancci3_2612
FREFranean1_4874
FRIFraEuI1c_3746
FALFRAAL2878
FSYFsymDg_2220
ACEAcel_1191
NMLNamu_2960
NAKEH165_06940(pafA)
GOBGobs_2684
BSDBLASA_2671(pafA)
MMARMODMU_2605(pafA)
KRAKrad_1875
SENSACE_2254
SACGFDZ84_01905(pafA)
SVISvir_21990
SACCEYD13_12255(pafA)
AMDAMED_4890
AMNRAM_24890
AMMAMES_4831
AMZB737_4831
AOIAORI_3826(pafA)
AJAAJAP_20030(pafA)
AMQAMETH_3535
AMYCCU254_18280(pafA)
AMYBBKN51_11615
AABA4R43_10760
AMYYYIM_27265(pafA)
AORISD37_19635
AACDLWP59_15270(pafA)
PDXPsed_3293
PSEAWY02_02410
PSEEFRP1_12100
PSEHXF36_10485
PSEQAD006_18875
PECQAD017_26715
PHHAFB00_26015
PAUTPdca_33720(pafA)
PBROHOP40_24995(pafA)
APRECNX65_11435(pafA)
AMIAmir_2247
SESPBN6_31900(pafA)
SSYIEKG83_34120(pafA)
KALKALB_3053
KPHYAOZ06_20435
LEDBBK82_45170
AHMTL08_12085
ACTIUA75_12985
ACADUA74_12905
AHGAHOG_12190(pafA)
ACTAC1701_22595(pafA)
ALOCRK56432
PMADBAY61_16885
SACEGIY23_09930(pafA)
STPStrop_2247
SAQSare_2364
MAUMicau_2951
MILML5_5437
MICBMicB006_6068
MTUACSH63_10325(pafA)
MICHFJK98_18895(pafA)
MTEMGCE86_07040(pafA)
MCABHXZ27_17820(pafA)
MSAGGCM10017556_49320(pafA)
VMAVAB18032_22780
MCRAID554_27510(pafA)
ASEACPL_5241
AMSAMIS_53570
ACTNL083_5066
AFSAFR_26390
ACTSACWT_5111
AIHAiant_10110(pafA)
ACTRAsp14428_79310(pafA)
PLKCIK06_14035(pafA)
PLABC6361_03190(pafA)
PLATC6W10_18445(pafA)
PFLAPflav_035250(pafA)
PSUUPsuf_087310(pafA)
VERHUT12_17060(pafA)
ATLAthai_31080(pafA)
ASERAsera_43470(pafA)
PRYPrubr_68250(pafA)
CATICS0771_67890(pafA)
DVCDvina_36885(pafA)
NHYJQS43_13335(pafA)
CCAZCOUCH_18385(pafA)
CAICaci_2428
SNASnas_4459
NAVJQS30_07595(pafA)
GLYK3N28_08040(pafA)
AHEArch_0902
ARCAHC352_04355
APHOJTE88_04610
MCUHMPREF0573_10274 HMPREF0573_11657
TPYCQ11_00290
TPYOX956_05435
TBWNCTC13354_00055(pafA)
TPECHLG82_04580(pafA)
ASGFB03_01925
ACTTDDD63_05840(pafA)
AMYADJ76_03275
SOOFBF35_05170(pafA)
STUCG5S47_03550(pafA)
ACQAM609_05845
AOSAXE84_08970 AXE84_11460
ARDAXF14_11205
ACTPB6G06_04920
ACTCCHIBA101_1156 CHIBA101_1750
ACTOC3V41_03825(pafA)
ANEAN27039_2785
AHWNCTC11636_00462(pafA_1) NCTC11636_00835(pafA_2)
ACTZCWT12_05135(pafA)
AIRNCTC12972_00246(pafA_1) NCTC12972_00921(pafA_2)
ASLANCTC11923_01767(pafA_1) NCTC11923_02332(pafA_2)
AVCNCTC10951_00885(pafA_1) NCTC10951_01229(pafA_2)
AWEJG540_05645(pafA) JG540_07855
AMAMHPC72_04825(pafA) HPC72_07380
AREPID810_04445 ID810_06705(pafA)
AVUBK816_03975
FSLEJO69_01745(pafA) EJO69_10280
FLHEJ997_02820(pafA) EJ997_10020
BLOBL1797
BLJBLD_1975
BLNBlon_2124
BLONBLIJ_2201
BLFBLIF_1510
BLLBLJ_1494
BLBBBMN68_26
BLMBLLJ_1465
BLKBLNIAS_00680
BLGBIL_01800
BLZBLGT_07820
BLXGS08_07745
BADBAD_0549
BADLBADO_0563
BADOBBMN23_0595
BLABLA_1169
BLCBalac_0641
BLTBalat_0641
BBBBIF_01344
BBCBLC1_0614
BNMBALAC2494_00489
BLVBalV_0618
BLWW7Y_0645(pafA)
BLSW91_0666
BANIBl12_0598
BANLBLAC_03225
BNIBANAN_03200
BANMEN10_03265
BDEBDP_0755
BDNBBDE_0723
BBPBBPR_0634
BBIBBIF_0658(pafA)
BBFBBB_0618
BBVHMPREF9228_0491(pafA)
BBRUBbr_1380
BBREB12L_1321
BBRVB689b_1403
BBRJB7017_1582
BBRCB7019_1568
BBRNB2258_1355
BBRSBS27_1398
BBRDBBBR_1436
BASTBAST_1106
BTPD805_1148
BCORBCOR_0941
BKAAH68_03180
BKSBBKW_0615
BCATBBCT_0552
BPSPAH67_03540
BIIBINDI_0878
BANGBBAG_0455
BPSCBBPC_0603
BSCABBSC_0980
BCHOBcFMB_05605
BGXESN35_07595
BLEMBL8807_07570(pafA)
BEUBE0216_03500(pafA)
BSUEBS3272_04080
PDOPSDT_1158
AEYCDG81_14130(pafA)
EKEEK0264_18430(pafA)
JTLM6D93_10065(pafA)
ABAIIMCC26256_111152
AFOAfer_0912
AYMYM304_26020(pafA)
ATQGH723_09405(pafA)
AQZKSP35_04275(pafA)
IAMHC251_11035(pafA)
ERZER308_20560(pafA)
EUZDVS28_a2576
CCZCCALI_02217
FGIOP10G_3407
NPYNPRO_12610
MINMinf_1278
MKCkam1_1267
MEAPMTHMO_1823
AMOBHG15A2_04740(pafA)
NDENIDE0960 NIDE3054
NMVNITMOv2_0805 NITMOv2_3549(pafA)
NIONITINOP_1621 NITINOP_3237(pafA)
NJANSJP_0043(pafA) NSJP_1985
NKFNkreftii_001178
LFCLFE_0660
LFILFML04_0395 LFML04_1971
LFPY981_02025 Y981_10025
LEGABH19_02100 ABH19_10400
NLIG3M70_02760
MOXDAMO_0753
 » show all
Reference
1  [PMID:20355727]
  Authors
Sutter M, Damberger FF, Imkamp F, Allain FH, Weber-Ban E
  Title
Prokaryotic ubiquitin-like protein (Pup) is coupled to substrates via the side chain of its C-terminal glutamate.
  Journal
J Am Chem Soc 132:5610-2 (2010)
DOI:10.1021/ja910546x
Reference
2  [PMID:21081505]
  Authors
Guth E, Thommen M, Weber-Ban E
  Title
Mycobacterial ubiquitin-like protein ligase PafA follows a two-step reaction pathway with a phosphorylated pup intermediate.
  Journal
J Biol Chem 286:4412-9 (2011)
DOI:10.1074/jbc.M110.189282
Reference
3  [PMID:23471967]
  Authors
Ofer N, Forer N, Korman M, Vishkautzan M, Khalaila I, Gur E
  Title
Allosteric transitions direct protein tagging by PafA, the prokaryotic ubiquitin-like protein (Pup) ligase.
  Journal
J Biol Chem 288:11287-93 (2013)
DOI:10.1074/jbc.M112.435842
Reference
4  [PMID:23601177]
  Authors
Barandun J, Delley CL, Ban N, Weber-Ban E
  Title
Crystal structure of the complex between prokaryotic ubiquitin-like protein and its ligase PafA.
  Journal
J Am Chem Soc 135:6794-7 (2013)
DOI:10.1021/ja4024012
  Sequence
[cgl:Cgl1494]
Reference
5  [PMID:23557784]
  Authors
Striebel F, Imkamp F, Ozcelik D, Weber-Ban E
  Title
Pupylation as a signal for proteasomal degradation in bacteria.
  Journal
Biochim Biophys Acta 1843:103-13 (2014)
DOI:10.1016/j.bbamcr.2013.03.022
Other DBs
ExplorEnz - The Enzyme Database: 6.3.1.19
IUBMB Enzyme Nomenclature: 6.3.1.19
ExPASy - ENZYME nomenclature database: 6.3.1.19
BRENDA, the Enzyme Database: 6.3.1.19

DBGET integrated database retrieval system