KEGG   ENZYME: 6.3.1.4Help
Entry
EC 6.3.1.4                  Enzyme                                 

Name
aspartate---ammonia ligase (ADP-forming);
asparagine synthetase (ADP-forming);
asparagine synthetase (adenosine diphosphate-forming)
Class
Ligases;
Forming carbon-nitrogen bonds;
Acid-D-ammonia (or amine) ligases (amide synthases)
BRITE hierarchy
Sysname
L-aspartate:ammonia ligase (ADP-forming)
Reaction(IUBMB)
ATP + L-aspartate + NH3 = ADP + phosphate + L-asparagine [RN:R00482]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
L-aspartate [CPD:C00049];
NH3 [CPD:C00014]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
L-asparagine [CPD:C00152]
History
EC 6.3.1.4 created 1972
Reference
1  [PMID:5820987]
  Authors
Nair PM.
  Title
Asparagine synthetase from gamma-irradiated potatoes.
  Journal
Arch Biochem Biophys 133:208-15 (1969)
DOI:10.1016/0003-9861(69)90447-0
Other DBs
ExplorEnz - The Enzyme Database: 6.3.1.4
IUBMB Enzyme Nomenclature: 6.3.1.4
ExPASy - ENZYME nomenclature database: 6.3.1.4
BRENDA, the Enzyme Database: 6.3.1.4
CAS: 37318-61-9

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