KEGG   ENZYME: 6.3.2.32
Entry
EC 6.3.2.32                 Enzyme                                 

Name
coenzyme gamma-F420-2:alpha-L-glutamate ligase;
MJ1001;
CofF protein;
gamma-F420-2:alpha-L-glutamate ligase
Class
Ligases;
Forming carbon-nitrogen bonds;
Acid-D-amino-acid ligases (peptide synthases)
Sysname
L-glutamate:coenzyme gamma-F420-2 (ADP-forming)
Reaction(IUBMB)
ATP + coenzyme gamma-F420-2 + L-glutamate = ADP + phosphate + coenzyme alpha-F420-3 [RN:R09401]
Reaction(KEGG)
R09401
Substrate
ATP [CPD:C00002];
coenzyme gamma-F420-2 [CPD:C00876];
L-glutamate [CPD:C00025]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
coenzyme alpha-F420-3 [CPD:C19151]
Comment
The enzyme caps the gamma-glutamyl tail of the hydride carrier coenzyme F420 [1].
History
EC 6.3.2.32 created 2010
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K14940  gamma-F420-2:alpha-L-glutamate ligase
Genes
SON: SO_2200(rimK)
SAZ: Sama_1999
SBL: Sbal_1848
SBM: Shew185_1834
SBN: Sbal195_1882
SBP: Sbal223_2443
SBT: Sbal678_1921
SBS: Sbal117_1966
SBB: Sbal175_2505
SPC: Sputcn32_1744
SKH: STH12_01689(rimK_4)
PSEO: OM33_05960
PSPO: PSPO_a0609(cofF)
PTU: PTUN_a3869(cofF)
PSEN: PNC201_06600(rimK1)
LHA: LHA_0303
LCD: clem_13645(rimK_3)
TSV: DSM104635_01004(lysX)
SMAZ: LH19_12250
SPHM: G432_12675
MAI: MICA_511
MAN: A11S_494
BMX: BMS_2472
BBEV: BBEV_0975(rimK-2)
OIH: OB2060
VPN: A21D_03084(lysX) A21D_03085(rimK)
HSC: HVS_08550(rimK1) HVS_08555(rimK2)
CPY: Cphy_2753
CGV: CGLAU_09760(rimK)
AFO: Afer_0709
WCH: wcw_1112(rimK)
SNG: SNE_A10260(rimK)
PROC: Ptc2401_00937(lysX_1)
MJA: MJ_1001
MMP: MMP0170(cofF)
MMD: GYY_00870
MMAK: MMKA1_01750(cofF)
MMAO: MMOS7_02010(cofF)
MMAD: MMJJ_09140(rimK_2)
MAE: Maeo_1379
METF: CFE53_01290(cofF)
FPL: Ferp_2172
MAC: MA_1361(rimK)
MMA: MM_2347
MMAC: MSMAC_2094
MHOR: MSHOH_2976
MMET: MCMEM_1893
MPY: Mpsy_2134(rimK)
 » show all
Reference
1  [PMID:12909715]
  Authors
Li H, Xu H, Graham DE, White RH
  Title
Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses.
  Journal
Proc Natl Acad Sci U S A 100:9785-90 (2003)
DOI:10.1073/pnas.1733391100
  Sequence
[mja:MJ_1001]
Other DBs
ExplorEnz - The Enzyme Database: 6.3.2.32
IUBMB Enzyme Nomenclature: 6.3.2.32
ExPASy - ENZYME nomenclature database: 6.3.2.32
BRENDA, the Enzyme Database: 6.3.2.32

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