KEGG   ENZYME: 6.3.2.32
Entry
EC 6.3.2.32                 Enzyme                                 
Name
coenzyme gamma-F420-2:alpha-L-glutamate ligase;
MJ1001;
CofF protein;
gamma-F420-2:alpha-L-glutamate ligase
Class
Ligases;
Forming carbon-nitrogen bonds;
Acid-D-amino-acid ligases (peptide synthases)
Sysname
L-glutamate:coenzyme gamma-F420-2 (ADP-forming)
Reaction(IUBMB)
ATP + coenzyme gamma-F420-2 + L-glutamate = ADP + phosphate + coenzyme alpha-F420-3 [RN:R09401]
Reaction(KEGG)
R09401
Substrate
ATP [CPD:C00002];
coenzyme gamma-F420-2 [CPD:C00876];
L-glutamate [CPD:C00025]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
coenzyme alpha-F420-3 [CPD:C19151]
Comment
The enzyme caps the gamma-glutamyl tail of the hydride carrier coenzyme F420 [1].
History
EC 6.3.2.32 created 2010
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K14940  gamma-F420-2:alpha-L-glutamate ligase
Genes
SONSO_2200(rimK)
SAZSama_1999
SBLSbal_1848
SBMShew185_1834
SBNSbal195_1882
SBPSbal223_2443
SBTSbal678_1921
SBSSbal117_1966
SBBSbal175_2505
SPCSputcn32_1744
SHPSput200_1771
SHEShewmr4_2195
SHMShewmr7_2272
SHNShewana3_2405
SHWSputw3181_2281
SHFCEQ32_03360
SBJCF168_08980
SHEWCKQ84_21855
SALGBS332_16795
SKHSTH12_01689(rimK_4)
SLITJQC75_10225
SCAATUM17387_22460(rimK)
SCYPJYB88_07550
SSEMJYB85_07750
SXMMKD32_11265
PSEOOM33_05960
PRRAT705_00405
PPISB1L02_10160
PSPOPSPO_a0609(cofF)
PTUPTUN_a3869(cofF)
PSENPNC201_06600(rimK1)
PDJD0907_18800
PXIJ5O05_16465
PVBJ5X90_12805
FBLFbal_1405 Fbal_3320
LHALHA_0303
LCDclem_13645(rimK_3)
LGTE4T54_06750
MGEOCFI10_11795
MSECLN244_09405
DVEDESUT3_08310
TSVDSM104635_01004(lysX)
THAACFI11_16260
CBOTATE48_15055
NREBES08_00495
NOVTQ38_005500
SMAZLH19_12250
SPHMG432_12675
SSANNX02_01805 NX02_02790
SUFLFIL70_03915
CMANA9D14_02485
MAIMICA_511
MANA11S_494
BMXBMS_2472
BSHILGQ02_14785
BCOBcell_3109 Bcell_3110
BHKB4U37_16110
OIHOB2060
TAPGZ22_09970 GZ22_09975
TAIDKS242_11130
VIRX953_09135
VHLBME96_08020 BME96_08025
VIGBKP57_01650
VILCFK37_13350 CFK37_13355
VNECFK40_08770
VPNA21D_03084(lysX) A21D_03085(rimK)
LAOAOX59_06080 AOX59_06085
BSJUP17_17620
BMURABE28_016420
PBUTDTO10_04465
PFRIL8956_18255
AQTFN924_11475
GRCGI584_04560 GI584_04585
POFGS400_14495 GS400_14500
SEDDERJ70_12135 ERJ70_12140
CTHUHUR95_15415
BBEVBBEV_0975(rimK-2)
GAJMY490_21310
HSCHVS_08550(rimK1) HVS_08555(rimK2)
CPYCphy_2753
ANRAna3638_16390 Ana3638_16395
ACELacsn021_27150
ACHTbsdcttw_29060
SSUNH9Q77_00155
TEBT8CH_0003(rimK)
AWOAwo_c26080 Awo_c26090
AWICHL1_000930 CHL1_000931
CBARPATL70BA_1083
CGVCGLAU_09760(rimK)
CLIZG7Y31_08915
CLUJIAU68_08985
ACITHPK19_17060 HPK19_17065
AFOAfer_0709
PMETG4Y79_21850
WCHwcw_1112(rimK)
SNGSNE_A10260(rimK)
SFCSpiaf_0383
SPEREW093_12210
PSTYBFS30_01295
FSDLXD69_15515
PROCPtc2401_00937(lysX_1)
TAVG4V39_06485
CDESC0J27_04220
MJAMJ_1001
MFEMefer_1229
MVUMetvu_1301
MFSMFS40622_1616
MIFMetin_0765
MJHJH146_0956
MESGMLAUSG7_0153(cofF)
MESAMLASG1_1332(cofF)
MIGMetig_0022
MMPMMP0170(cofF)
MMQMmarC5_1505
MMXMmarC6_0780
MMZMmarC7_1170
MMDGYY_00870
MMAKMMKA1_01750(cofF)
MMAOMMOS7_02010(cofF)
MMADMMJJ_09140(rimK_2)
MAEMaeo_1379
MVNMevan_1175
MVOMvol_1166 Mvol_1455
MOKMetok_0654
METFCFE53_01290(cofF)
FPLFerp_2172
MACMA_1361(rimK)
MMAMM_2347
MMAZMmTuc01_2397
MMJMSMAS_2353
MMACMSMAC_2094
MLSMSLAZ_0946
MEFMSWH1_2290
MEQMSWHS_2785
MHORMSHOH_2976
MMETMCMEM_1893
MELOJ7W08_08415
MZHMzhil_0669
MPYMpsy_2134(rimK)
 » show all
Reference
1  [PMID:12909715]
  Authors
Li H, Xu H, Graham DE, White RH
  Title
Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses.
  Journal
Proc Natl Acad Sci U S A 100:9785-90 (2003)
DOI:10.1073/pnas.1733391100
  Sequence
[mja:MJ_1001]
Other DBs
ExplorEnz - The Enzyme Database: 6.3.2.32
IUBMB Enzyme Nomenclature: 6.3.2.32
ExPASy - ENZYME nomenclature database: 6.3.2.32
BRENDA, the Enzyme Database: 6.3.2.32

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