KEGG   ENZYME: 6.3.2.62
Entry
EC 6.3.2.62                 Enzyme                                 
Name
beta-tubulin-glutamate ligase;
beta-tubulin polyglutamylase;
TTLL4 (ambiguous);
TTLL7 (ambiguous)
Class
Ligases;
Forming carbon-nitrogen bonds;
Acid-D-amino-acid ligases (peptide synthases)
Sysname
[beta-tubulin]-L-glutamate:L-glutamate ligase (ADP-forming)
Reaction(IUBMB)
n ATP + [beta-tubulin]-L-glutamate + n L-glutamate = [beta-tubulin]-(gamma-(poly-alpha-L-glutamyl)-L-glutamyl)-L-glutamate + n ADP + n phosphate (overall reaction);
(1a) ATP + [beta-tubulin]-L-glutamate + L-glutamate = [beta-tubulin]-(gamma-L-glutamyl)-L-glutamate + ADP + phosphate;
(1b) ATP + [beta-tubulin]-(gamma-L-glutamyl)-L-glutamate + L-glutamate = [beta-tubulin]-(alpha-L-glutamyl-gamma-L-glutamyl)-L-glutamate + ADP + phosphate;
(1c) ATP + [beta-tubulin]-(alpha-L-glutamyl-gamma-L-glutamyl)-L-glutamate + n L-glutamate = [beta-tubulin]-(gamma-(poly-alpha-L-glutamyl)-L-glutamyl)-L-glutamate + n ADP + n phosphate
Substrate
ATP [CPD:C00002];
[beta-tubulin]-L-glutamate;
L-glutamate [CPD:C00025];
[beta-tubulin]-(gamma-L-glutamyl)-L-glutamate;
[beta-tubulin]-(alpha-L-glutamyl-gamma-L-glutamyl)-L-glutamate
Product
[beta-tubulin]-(gamma-(poly-alpha-L-glutamyl)-L-glutamyl)-L-glutamate;
ADP [CPD:C00008];
phosphate [CPD:C00009];
[beta-tubulin]-(gamma-L-glutamyl)-L-glutamate;
[beta-tubulin]-(alpha-L-glutamyl-gamma-L-glutamyl)-L-glutamate
Comment
The eukaryotic tubulin proteins, which polymerize into microtubules, are highly modified by the addition of side-chains. The polyglutamylation reaction catalysed by this group of enzymes consists of two biochemically distinct steps: initiation and elongation. Initiation comprises the formation of an isopeptide bond with the gamma-carboxyl group of the glutamate acceptor site, whereas elongation consists of the addition of glutamate residues linked by regular peptide bonds to the gamma-linked residue. This entry describes enzymes that act on beta-tubulins and other proteins with glutamate-rich regions but not on alpha-tubulins.
History
EC 6.3.2.62 created 2021
Orthology
K16583  tubulin polyglutamylase TTLL7
K16601  tubulin polyglutamylase TTLL4
Genes
HSA79739(TTLL7) 9654(TTLL4)
PTR456975(TTLL7) 459949(TTLL4)
PPS100969896(TTLL7) 100989250(TTLL4)
GGO101131187(TTLL4) 101139105(TTLL7)
PON100439538(TTLL4) 100457636(TTLL7)
NLE100583242(TTLL7) 100598713(TTLL4)
MCC700064(TTLL4) 709536(TTLL7)
MCF101925426(TTLL4) 102126179(TTLL7)
CSAB103217879(TTLL4) 103224541(TTLL7)
CATY105587104(TTLL4) 105593560(TTLL7)
PANU101006322(TTLL7) 101026846(TTLL4)
TGE112610414(TTLL7) 112636530(TTLL4)
RRO104660031(TTLL4) 104677488(TTLL7)
RBB108518471(TTLL4) 108527681(TTLL7)
TFN117092157(TTLL7) 117094513(TTLL4)
PTEH111540448(TTLL7) 111548680(TTLL4)
CJC100393425(TTLL4) 100407330(TTLL7)
SBQ101029335(TTLL4) 101049008(TTLL7)
CSYR103261234(TTLL4)
MMUR105857700(TTLL4) 105863923(TTLL7)
LCAT123635478(TTLL7) 123644000(TTLL4)
OGA100948580(TTLL4) 100967049(TTLL7)
MMU67534(Ttll4) 70892(Ttll7)
MCAL110290921(Ttll7) 110292286(Ttll4)
MPAH110320073(Ttll7) 110321819(Ttll4)
RNO310982(Ttll7) 690512(Ttll4)
MCOC116088581(Ttll4) 116093930(Ttll7)
MUN110555017(Ttll7) 110566754(Ttll4)
CGE100767380(Ttll7) 100770741(Ttll4)
MAUA101827444(Ttll7) 101842948(Ttll4)
PLEU114698261(Ttll7) 114709279(Ttll4)
MORG121445770(Ttll7) 121447069(Ttll4)
AAMP119801024(Ttll7) 119820575(Ttll4)
NGI103727726(Ttll4) 103728094(Ttll7)
HGL101700742(Ttll4) 101722842(Ttll7)
CPOC100712966(Ttll7) 100725277(Ttll4)
CCAN109675273(Ttll4) 109700438(Ttll7)
DORD105982307(Ttll4) 105987030(Ttll7)
DSP122107440(Ttll4) 122110527(Ttll7)
NCAR124980195 124986825
OCU100342462(TTLL7) 100347979(TTLL4)
OPI101527045(TTLL7) 101530495(TTLL4)
TUP102469123(TTLL7) 102472286(TTLL4)
CFA479976(TTLL7) 488525(TTLL4)
VVP112922545(TTLL4) 112924476(TTLL7)
VLG121480743(TTLL4) 121487685(TTLL7)
AML100470797(TTLL7) 100480405(TTLL4)
UMR103662756(TTLL4) 103662973(TTLL7)
UAH113250447(TTLL4) 113254488(TTLL7)
UAR123779436(TTLL4) 123795274(TTLL7)
ELK111143226 111144057
LLV125095157 125098057
MPUF101689941(TTLL4) 101693743(TTLL7)
ORO101368001(TTLL7) 101374019(TTLL4)
EJU114200165(TTLL4) 114208459(TTLL7)
ZCA113912271(TTLL7) 113920108(TTLL4)
MLX118012035(TTLL4) 118019229(TTLL7)
FCA101090956(TTLL7) 101099141(TTLL4)
PYU121027377(TTLL7) 121031076(TTLL4)
PBG122480697(TTLL7) 122481777(TTLL4)
PTG102958552(TTLL4) 102972445(TTLL7)
PPAD109246174(TTLL7) 109265058(TTLL4)
AJU106970104(TTLL4) 106973353(TTLL7)
HHV120232433(TTLL4) 120241643(TTLL7)
BTA511853(TTLL4) 522221(TTLL7)
BOM102269774(TTLL7) 102275485(TTLL4)
BIU109556139(TTLL7) 109570709(TTLL4)
BBUB102398101(TTLL4) 102412604(TTLL7)
CHX102169242(TTLL7) 102171385(TTLL4)
OAS101108264(TTLL7) 101112884(TTLL4)
ODA120854367(TTLL4) 120856948(TTLL7)
CCAD122426476(TTLL4) 122436775(TTLL7)
SSC100522876(TTLL7) 106506366(TTLL4)
CFR102507367(TTLL7) 102517472(TTLL4)
CBAI105064022(TTLL4) 105075500(TTLL7)
CDK105095032(TTLL7) 105096089(TTLL4)
VPC102536099(TTLL7) 102536359(TTLL4)
BACU102998378(TTLL4) 103008034(TTLL7)
LVE103080434(TTLL4) 103080907(TTLL7)
OOR101273672(TTLL7) 101289107(TTLL4)
DLE111171836(TTLL4) 111178382(TTLL7)
PCAD102973710(TTLL4) 102991608(TTLL7)
PSIU116740797(TTLL7) 116756852(TTLL4)
ECB100052881(TTLL7) 100055898(TTLL4)
EPZ103555094(TTLL7) 103561964(TTLL4)
EAI106824033(TTLL7) 106838457(TTLL4)
MYB102245218(TTLL7) 102255767(TTLL4)
MYD102759071(TTLL7) 102761112(TTLL4)
MMYO118661601(TTLL4) 118676798(TTLL7)
MLF102424449(TTLL4) 102437471(TTLL7)
MNA107524768(TTLL4) 107543198(TTLL7)
PKL118717007(TTLL4) 118723386(TTLL7)
HAI109380588(TTLL4) 109385431(TTLL7)
DRO112307975(TTLL4) 112309213(TTLL7)
SHON118975310(TTLL4) 118997373(TTLL7)
AJM119039519(TTLL4) 119062902(TTLL7)
PDIC114495270(TTLL4) 114497382(TTLL7)
PHAS123816577(TTLL7) 123829279(TTLL4)
MMF118625176(TTLL4) 118626387(TTLL7)
RFQ117026016(TTLL4) 117027011(TTLL7)
PALE102884218(TTLL4) 102898710(TTLL7)
PGIG120583267(TTLL7) 120587663(TTLL4)
PVP105289143(TTLL7) 105291054(TTLL4)
RAY107511592(TTLL7) 107516748(TTLL4)
MJV108390515(TTLL4) 108408345(TTLL7)
TOD119235085(TTLL7) 119256215(TTLL4)
SARA101541736(TTLL4) 101553494(TTLL7)
LAV100657249(TTLL7) 100662547(TTLL4)
TMU101342378 101347163
DNM101421927(TTLL7) 101423821(TTLL4)
MDO100010987(TTLL4) 100011255(TTLL7)
GAS123240149(TTLL4) 123245425(TTLL7)
SHR100917952(TTLL7) 100934089(TTLL4)
PCW110209922(TTLL7) 110219464(TTLL4)
OAA100075137(TTLL7) 114811195(TTLL4)
GGA424209(TTLL4) 424543(TTLL7)
PCOC116227311(TTLL4) 116233379(TTLL7)
MGP100539357 100551316(TTLL7) 104911681
CJO107316912(TTLL4) 107317469(TTLL7)
NMEL110400528(TTLL4) 110402969(TTLL7)
APLA101790601(TTLL7) 101803632(TTLL4)
ACYG106034069(TTLL7) 106039369
AFUL116490904(TTLL4) 116492146(TTLL7)
TGU100225080(TTLL7) 100225583(TTLL4)
LSR110468347(TTLL4) 110468835(TTLL7)
SCAN103814666(TTLL4) 103814928(TTLL7)
PMOA120496618(TTLL4) 120510815(TTLL7)
OTC121335653(TTLL4) 121344952(TTLL7)
PRUF121356762(TTLL4) 121361917(TTLL7)
GFR102036790(TTLL4) 102039813(TTLL7)
FAB101818914(TTLL4) 101821262(TTLL7)
PHI102102484(TTLL4) 102113109(TTLL7)
PMAJ107207519(TTLL4) 107208346(TTLL7)
CCAE111932185(TTLL4) 111932865(TTLL7)
CCW104694194 104695297(TTLL7)
ETL114055260(TTLL4) 114064915(TTLL7)
ZAB102065157(TTLL4) 102069321(TTLL7)
FPG101917588(TTLL7) 101921043(TTLL4)
FCH102051624(TTLL7) 102054406(TTLL4)
CLV102084260(TTLL4) 102093862(TTLL7)
EGZ104122906(TTLL7) 104132406(TTLL4)
NNI104010069(TTLL4) 104015566(TTLL7)
PLET104619748(TTLL7) 104625565(TTLL4)
ACUN113482390(TTLL4) 113483001(TTLL7)
TALA104366402(TTLL7) 104368005(TTLL4)
PADL103917662(TTLL4) 103925151(TTLL7)
ACHC115342633(TTLL4) 115349378(TTLL7)
AAM106499325(TTLL4) 106499822(TTLL7)
AROW112961919(TTLL7) 112972006(TTLL4)
NPD112946261(TTLL7) 112959787(TTLL4)
DNE112980284(TTLL4) 112993151(TTLL7)
ASN102372829(TTLL7) 102377954(TTLL4)
AMJ102570549(TTLL4) 102572371(TTLL7)
CPOO109307349(TTLL7) 109323171(TTLL4)
GGN109286783(TTLL7) 109301589(TTLL4)
PSS102455547(TTLL7) 102460067(TTLL4)
CMY102936581(TTLL4) 102943081(TTLL7)
CPIC101943962(TTLL4) 101946119(TTLL7)
TST117881804(TTLL7) 117884947(TTLL4)
CABI116824546(TTLL4) 116835752(TTLL7)
MRV120369996(TTLL7) 120375023(TTLL4)
ACS100558945(ttll7) 100564234(ttll4)
PVT110078180(TTLL4) 110079749(TTLL7)
SUND121928524(TTLL7) 121930706(TTLL4)
PBI103053262(TTLL4) 103058112(TTLL7)
PMUR107294018(TTLL7) 107298011(TTLL4)
TSR106543376(TTLL7) 106547371(TTLL4)
PGUT117675272(TTLL4) 117677127(TTLL7)
VKO123024557(TTLL7) 123027356(TTLL4)
PMUA114598816(TTLL7) 114602828(TTLL4)
ZVI118088696(TTLL7) 118090814(TTLL4)
GJA107117294(TTLL7) 107122045(TTLL4)
STOW125425948(TTLL4) 125432720(TTLL7)
XLA108701293(ttll4.L) 108702932(ttll4.S) 108715498(ttll7.S) 443899(ttll7.L)
XTR100038218(ttll7) 100144652(ttll4)
NPR108784346(TTLL7) 108785768(TTLL4)
RTEM120944177(TTLL4) 120945983(TTLL7)
BBUF120979294(TTLL7) 121008117(TTLL4)
BGAR122943582(TTLL7) 122944872(TTLL4)
DRE558702(ttll4) 565243(ttll7)
SRX107738099 107742903(ttll7) 107745334 107752897
SANH107658573(ttll7) 107668375 107669020 107688755
SGH107560414 107592566(ttll7) 107593000 107596548
CCAR109062974 109068721 109085112
CAUA113053618 113069367 113108868
PPRM120464255(ttll7) 120486951(ttll4)
MAMB125256616(ttll7) 125270103(ttll4) 125270104
IPU108266949(ttll4) 108270711(ttll7)
PHYP113526280(ttll4) 113530372(ttll7)
SMEO124382925(ttll4) 124391338(ttll7)
TFD113651541(ttll7) 113654155(ttll4)
AMEX103028996(ttll7) 103047112(ttll4)
EEE113578546(ttll4) 113581915(ttll7)
TRU101062715(ttll7) 101063555(ttll4)
TNGGSTEN00022856G001 GSTEN00029112G001
LCO104917772(ttll7) 104932502(ttll4)
NCC104942931(ttll4)
CGOB115007336(ttll7) 115026269(ttll4)
ELY117251215(ttll4) 117254442(ttll7)
PLEP121941377(ttll7) 121948954(ttll4)
SLUC116055263(ttll4) 116055322(ttll7)
ECRA117950625(ttll7) 117952443(ttll4)
PFLV114561165(ttll7) 114564346(ttll4)
GAT120823937(ttll7) 120833599(ttll4)
PPUG119216422(ttll7) 119228506(ttll4)
MSAM119900628(ttll7) 119904534(ttll4)
CUD121511787(ttll7) 121522429(ttll4)
ALAT119025781(ttll4) 119029017(ttll7)
MZE101473151(ttll7) 101485525(ttll4)
ONL100691840(ttll7) 100703475 109194236
OAU116332025(ttll4) 116333064(ttll7)
OLA101160724(ttll7) 101171290(ttll4)
OML112150621(ttll7) 112155068(ttll4)
XMA102225205(ttll4) 102230009(ttll7)
XCO114148416(ttll4) 114151283(ttll7)
XHE116723242(ttll4) 116726118(ttll7)
PRET103464160(ttll7) 103482271(ttll4)
PFOR103130793(ttll7) 103149939(ttll4)
PLAI106954892(ttll7) 106963233(ttll4)
PMEI106923624(ttll7) 106930970(ttll4)
GAF122838693(ttll7) 122839439(ttll4)
CVG107087229(ttll7) 107101415(ttll4)
CTUL119774609(ttll7) 119794058(ttll4)
GMU124871291(ttll4) 124874040(ttll7)
NFU107390278(ttll4) 107392710(ttll7)
KMR108232327(ttll4) 108234362(ttll7)
ALIM106511281(ttll7) 106534065(ttll4)
NWH119419440(ttll4) 119430788(ttll7)
AOCE111575237(ttll4) 111580530
CSEM103391740(ttll4) 103392188(ttll7)
POV109625303(ttll7) 109647088(ttll4)
SSEN122760193(ttll4) 122780801(ttll7)
HHIP117755111(ttll4) 117759912(ttll7)
HSP118120110(ttll4) 118121427(ttll7)
LCF108872818(ttll4) 108881270(ttll7)
SDU111218044(ttll4) 111231765(ttll7)
SLAL111658499(ttll7) 111673152(ttll4)
XGL120790322(ttll7) 120801410(ttll4)
HCQ109519274(ttll4) 109522034(ttll7)
BPEC110156166(ttll4) 110160029(ttll7)
MALB109952773(ttll4) 109958207(ttll7)
BSPL114847495(ttll4) 114854426(ttll7)
SASA106586929(ttll4) 106613441(ttll7)
OTW112217411(ttll7) 112239702(ttll4)
OMY110520665(ttll4) 110521953(ttll7)
OGO123994966(ttll7) 124025754 124044303(ttll4)
ONE115126815 115139543(ttll7)
SALP111975871(ttll7) 112076868 112078168
SNH120036268 120054596(ttll7) 120064055
ELS105027968(ttll4)
SFM108920721(ttll4) 108923527(ttll7)
PKI111840808(ttll4) 111860533(ttll7)
AANG118214548 118223157(ttll4) 118226502(ttll7)
LOC102685677(ttll4) 102689936(ttll7)
PSPA121323628(ttll4) 121331093
ARUT117401365 117402312(ttll4) 117416709
LCM102365237(TTLL7) 102365402(TTLL4)
CMK103174713(ttll7) 103190531(ttll4)
RTP109917784(ttll7) 109918572(ttll4)
BFO118424100 118431376
BBEL109461787 109475180
CIN100179385 100180570
SCLV120336349 120342420
SPU115918125 576625 586239
APLC110973515 110977456
SKO100371126 100378590
DMEDmel_CG16833(TTLL4A) Dmel_CG3964(TTLL4B)
DER6541351 6541370
DSE6612097 6613295
DSIDsimw501_GD23261(Dsim_GD23261) Dsimw501_GD23748(Dsim_GD23748)
DYADyak_GE18264 Dyak_GE18502
DAN6497854 6498645
DSR110183483 110187566
DPODpse_GA17808
DPE6588704 6589002
DMN108161704 108162564
DWI6641981 6642282
DGR6561583 6562134
DMODmoj_GI18116 Dmoj_GI18156
DAZ108610682 108610958
DNV115562500 115564103
DHE111592604 111605519
DVI6627759 6635693
CCAT101449645
BOD106619791
MDE101893320 101894992
SCAC106091855 106091953
LCQ111678548 111679952
LSQ119601648 119602676
HIS119647082 119647249 119658843
AGAAgaP_AGAP009150
ACOZ120958467
AARA120903633
ASTE118514512
AAG5572804
AALB109427916
CQUCpipJ_CPIJ018042 CpipJ_CPIJ020016
CPII120412789
CNS116336987
BCOO119078727
AME102654331 413213 724379
ACER107998098 108004451 108004483
ALAB122712282 122715553 122715587
BIM100744079 100744994 112212130
BBIF117205869 117212966 117213028
BVK117235531 117241993 117242000
BVAN117153846 117154993 117154994
BTER100647821 105667155
BPYO122566396 122575218 122575219
CCAL108627987 108627989 113464708
OBB114873886 114873887 114880192
MGEN117219088 117219089 117220296
NMEA116428980 116428981
CGIG122403791 122403798
SOC105207399
MPHA105834028
AEC105153034
ACEP105622882
PBAR105434240
VEM105567090
HST105192320
DQU106747079
CFO105256308
FEX115244092
LHU105670992
PGC109856479
OBO105277337
PCF106785064 106785090
PFUC122519395 122519399 122520270
VPS122632090 122632091 122632092
MDL103572983
CGLO123275252
FAS105272057
DAM107038619
AGIF122852316
CCIN107273442
TCA103314096
DPA109544552
SOY115891650
ATD109600356
CSET123316383
AGB108915089
LDC111511480
NVL108564577
APLN108733051 108738847
PPYR116178677
OTU111413600
BMOR101739701
BMAN114250173
MSEX115444446
DPLKGM_212027
BANY112046572
PMAC106717465
PPOT106104195
PXU106116741
PRAP110992482
ZCE119829086
HAW110373737
TNL113499469
SLIU111348676
OFU114352356
PXY105387615
API100164638 100166302 100167599
DNX107171588 107173180
AGS114121021 114127729 114128106 114128347
RMD113556368 113556903 113557238 113558398
BTAB109038658
DCI103505298
CLEC106667057
HHAL106684985
NLU111052023
PHUPhum_PHUM529500
FOC113210128
ZNE110834225
CSEC111864263
FCD110859235
DPXDAPPUDRAFT_311295
DMK116927575
PVM113822023
PJA122265484
PCHN125042369
HAME121864599
PCLA123746524
PTRU123499602
HAZT108678371
EAF111697541 111702235 111709314 111710889
LSM121113632 121114688
ISCIscW_ISCW021095
RSAN119385494
RMP119178459
VDE111244608
VJA111272337
DPTE113795553
DFR124499428
CSCU111613060 111636319
PTEP107454048
SDM118188641
CELCELE_ZK1128.6(ttll-4)
CBRCBG_09874(Cbr-ttll-4)
BMYBM_BM7636(Bma-ttll-4)
LOALOAG_09898
NAINECAME_05644
TSPTsp_01754
HROHELRODRAFT_155740
LGILOTGIDRAFT_139346 LOTGIDRAFT_228133
PCAN112563835 112574512
BGT106059335 106069449
GAE121375051 121380976
HRF124145450
HRJ124276781 124279877
CRG105348489 105348914 117684924
MYI110457542 110463175
PMAX117325288 117343465
MMER123524432 123532844
OBI106872256 106880354
OSN115216319 115223633
LAK106154113 106154290 106154713 106154733 106154734 106157142 106157788 106157789 106157793 106164269 106164270 106164467 106164765 106164767 106165181 106165182 106175538 106176035 106176036 106176051
SMMSmp_155240 Smp_163450 Smp_181160
SHXMS3_0014856 MS3_0019072 MS3_0019238
OVIT265_08919 T265_11606 T265_14005
EGLEGR_03267 EGR_05164
NVE5509694 5517456
EPA110241167 110247421
ATEN116286940 116308370
ADF107338270 107340561
AMIL114968390 114971559
PDAM113678639 113683888
SPIS111322632 111333776
DGT114519928 114521942 114535920
XEN124439889 124445396 124456526
HMG100201129
TADTRIADDRAFT_22586 TRIADDRAFT_59327
AQU100633602 100635385 109584099
MBRMONBRDRAFT_28196 MONBRDRAFT_8219
SREPTSG_00722 PTSG_04117
TETTTHERM_00758970 TTHERM_00985000
PTMGSPATT00001174001 GSPATT00002846001 GSPATT00020419001 GSPATT00023650001
SMINv1.2.001043.t1(symbB.v1.2.001043.t1) v1.2.021109.t1(symbB.v1.2.021109.t1)
PIFPITG_02465
PSOJPHYSODRAFT_467093
SPARSPRG_00915
EHXEMIHUDRAFT_42604 EMIHUDRAFT_42614
GTTGUITHDRAFT_115074 GUITHDRAFT_135992
TBRTb09.211.1170
TBGTbgDal_IX5460
TCR506885.270
LMALMJF_35_4930
LIFLINJ_35_4980
LDOLDBPK_354980
LMILMXM_34_4930
LBZLBRM_34_4880
LPANLPMP_344770
TVATVAG_016930 TVAG_026590 TVAG_150310 TVAG_161030 TVAG_170080 TVAG_202010 TVAG_268230 TVAG_362380 TVAG_431700 TVAG_445340
GLAGL50803_008592
 » show all
Reference
1  [PMID:9622491]
  Authors
Regnard C, Audebert S, Desbruyeres, Denoulet P, Edde B.
  Title
Tubulin polyglutamylase: partial purification and enzymatic properties.
  Journal
Biochemistry 37:8395-404 (1998)
DOI:10.1021/bi9804131
Reference
2  [PMID:10564646]
  Authors
Regnard C, Desbruyeres E, Denoulet P, Edde B.
  Title
Tubulin polyglutamylase: isozymic variants and regulation during the cell cycle in HeLa cells.
  Journal
J Cell Sci 112 ( Pt 23):4281-9 (1999)
Reference
3  [PMID:16901895]
  Authors
Ikegami K, Mukai M, Tsuchida J, Heier RL, Macgregor GR, Setou M.
  Title
TTLL7 is a mammalian beta-tubulin polyglutamylase required for growth of MAP2-positive neurites.
  Journal
J Biol Chem 281:30707-16 (2006)
DOI:10.1074/jbc.M603984200
  Sequence
[mmu:70892]
Reference
4  [PMID:18045879]
  Authors
van Dijk J, Miro J, Strub JM, Lacroix B, van Dorsselaer A, Edde B, Janke C.
  Title
Polyglutamylation is a post-translational modification with a broad range of substrates.
  Journal
J Biol Chem 283:3915-22 (2008)
DOI:10.1074/jbc.M705813200
  Sequence
[mmu:67534]
Other DBs
ExplorEnz - The Enzyme Database: 6.3.2.62
IUBMB Enzyme Nomenclature: 6.3.2.62
ExPASy - ENZYME nomenclature database: 6.3.2.62
BRENDA, the Enzyme Database: 6.3.2.62

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