Entry |
|
Name |
UDP-N-acetylmuramate---L-alanine ligase;
MurC synthetase;
UDP-N-acetylmuramoyl-L-alanine synthetase;
uridine diphospho-N-acetylmuramoylalanine synthetase;
UDP-N-acetylmuramoylalanine synthetase;
L-alanine-adding enzyme;
UDP-acetylmuramyl-L-alanine synthetase;
UDPMurNAc-L-alanine synthetase;
L-Ala ligase;
uridine diphosphate N-acetylmuramate:L-alanine ligase;
uridine 5'-diphosphate-N-acetylmuramyl-L-alanine synthetase;
uridine-diphosphate-N-acetylmuramate:L-alanine ligase;
UDP-MurNAc:L-alanine ligase;
alanine-adding enzyme;
UDP-N-acetylmuramyl:L-alanine ligase;
UDP-N-acetylmuramate:L-alanine ligase (ADP-forming)
|
Class |
Ligases;
Forming carbon-nitrogen bonds;
Acid-D-amino-acid ligases (peptide synthases)
|
Sysname |
UDP-N-acetyl-alpha-D-muramate:L-alanine ligase (ADP-forming)
|
Reaction(IUBMB) |
ATP + UDP-N-acetyl-alpha-D-muramate + L-alanine = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine [RN: R03193]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
ADP [CPD: C00008];
phosphate [CPD: C00009];
UDP-N-acetyl-alpha-D-muramoyl-L-alanine [CPD: C01212]
|
Comment |
Involved in the synthesis of a cell-wall peptide in bacteria.
|
History |
EC 6.3.2.8 created 1965, modified 2002
|
Pathway |
|
Orthology |
K01924 | UDP-N-acetylmuramate--alanine ligase |
|
Genes |
ECOO: | ECRM13514_0095(murC) |
ECOH: | ECRM13516_0098(murC) |
ELR: | ECO55CA74_00450(murC) |
ECW: | EcE24377A_0093(murC) |
ECOA: | APECO78_03905(murC) |
EDJ: | ECDH1ME8569_0088(murC) |
ECOI: | ECOPMV1_00094(murC) |
SEM: | STMDT12_C01290(murC) |
SETC: | CFSAN001921_16775(murC) |
SEEN: | SE451236_06660(murC) |
SENH: | CFSAN002069_08580(murC) |
SEEH: | SEEH1578_09675(murC) |
SENJ: | CFSAN001992_10360(murC) |
SEEC: | CFSAN002050_07090(murC) |
SEEB: | SEEB0189_018740(murC) |
REE: | electrica_04242(murC) |
RTG: | NCTC13098_06203(murC) |
CLAP: | NCTC11466_03831(murC) |
KIE: | NCTC12125_02945(murC) |
METY: | MRY16398_47270(murC) |
PTF: | PROFFT_A_01760(murC) |
PSHI: | SAMEA2665130_0389(murC) |
YPG: | YpAngola_A2917(murC) |
YPI: | YpsIP31758_3386(murC) |
SMW: | SMWW4_v1c07480(murC) |
SERS: | SERRSCBI_03440(murC) |
SFJ: | SAMEA4384070_0786(murC) |
SOF: | NCTC11214_00761(murC) |
SSAR: | SSARUM_000691(murC) |
PAQU: | DMB82_0017160(murC) |
PARL: | PEC302110_33460(murC) |
DIC: | Dpoa569_000605(murC) |
EHD: | ERCIPSTX3056_386(murC) |
BAPF: | BUMPF009_CDS00379(murc) |
BAPG: | BUMPG002_CDS00380(murc) |
BAPU: | BUMPUSDA_CDS00379(murc) |
BAPW: | BUMPW106_CDS00380(murc) |
TPTY: | NCTC11468_03091(murC_1) |
PHEI: | NCTC12003_01247(murC) |
PRJ: | NCTC6933_02762(murC) |
LRI: | NCTC12151_02611(murC) |
HIC: | NTHIC486_01603(murC) |
HPIT: | NCTC13334_01200(murC) |
HHZ: | NCTC10839_01092(murC) |
HAEG: | NCTC8502_01263(murC) |
PDAG: | 4362423_00243(murC) |
ADP: | NCTC12871_01077(murC) |
ALIG: | NCTC10568_00021(murC) |
ASEG: | NCTC10977_00978(murC) |
AVT: | NCTC3438_00981(murC) |
RPNE: | NCTC8284_03142(murC) |
PAET: | NCTC13378_01313(murC) |
XFU: | XFF4834R_chr07840(murC) |
XPH: | XppCFBP6546_07535(XppCFBP6546P_07535) |
XHD: | LMG31886_35520(murC) |
LLZ: | LYB30171_02232(murC) |
VAU: | VANGNB10_cI2168c(murC) |
VPL: | SA104470976_00426(murC) |
PAEB: | NCGM1900_2241(murC) |
PVD: | CFBP1590__1174(murC) |
PPRC: | PFLCHA0_c50350(murC) |
PMUD: | NCTC8068_04354(murC) |
PFW: | PF1751_v1c09080(murC) |
PFF: | PFLUOLIPICF703590(murC) |
PPUU: | PputUW4_04502(murC) |
PTRT: | HU722_0005950(murC) |
PTW: | TUM18999_13420(murC) |
PTAE: | NCTC10697_00862(murC) |
MSHE: | MAALD49_08970(murC) |
PSYC: | DABAL43B_2328(murC) |
MCAT: | MC25239_00306(murC) |
MCUN: | NCTC10297_00842(murC) |
SCAA: | TUM17387_03650(murC) |
PLZ: | S4054249_18765(murC) |
SALH: | HMF8227_02469(murC) |
CBS: | COXBURSA331_A0225(murC) |
LLG: | 44548918_02411(murC) |
LJR: | NCTC11533_02578(murC) |
LCJ: | NCTC11976_03318(murC) |
LWA: | SAMEA4504053_3101(murC) |
LSS: | NCTC12082_01753(murC) |
LADL: | NCTC12735_00649(murC) |
LANT: | TUM19329_06120(murC) |
MISZ: | MishRS11D_06350(murC) |
TIB: | THMIRHAM_16370(murC) |
TSE: | THMIRHAS_19010(murC) |
TZO: | THMIRHAT_06770(murC) |
TFRI: | Thiofri_04394(murC) |
TNI: | TVNIR_2603(murC_[H]) |
GAI: | IMCC3135_29175(murC) |
THIC: | TspCOW1_31490(murC) |
HAAH: | HALA3H3_950050(murC) |
ALCA: | ASALC70_01146(murC_2) |
AEL: | NCTC12917_03781(murC) |
CHJ: | NCTC10426_02277(murC) |
CDIZ: | CEDIAZO_03158(murC) |
NMM: | NMBM01240149_1665(murC) |
NMS: | NMBM01240355_0432(murC) |
NMQ: | NMBM04240196_0431(murC) |
NMZ: | NMBNZ0533_1826(murC) |
NMX: | NMA510612_2326(murC) |
NWE: | SAMEA3174300_1585(murC) |
NZO: | SAMEA4504057_0383(murC) |
NCI: | NCTC10296_00400(murC) |
NCZ: | NCTC10294_01265(murC) |
NANI: | NCTC12227_02083(murC) |
ECOR: | SAMEA4412678_0474(murC) |
BMV: | BMASAVP1_A0471(murC) |
BML: | BMA10229_A1330(murC) |
BPM: | BURPS1710b_3543(murC) |
BPL: | BURPS1106A_3549(murC) |
BUE: | BRPE67_ACDS23640(murC) |
PLG: | NCTC10937_01078(murC) |
LMIR: | NCTC12852_00833(murC) |
BUO: | BRPE64_ACDS24160(murC) |
VTR: | MYVALT_F_00090(murC) |
BTRM: | SAMEA390648700548(murC) |
AXX: | ERS451415_00806(murC) |
LIM: | L103DPR2_02751(murC) |
LIH: | L63ED372_02317(murC) |
SMIO: | CATMQ487_12000(murC) |
URU: | DSM104443_00679(murC) |
UPL: | DSM104440_00645(murC) |
THAG: | CKCBHOJB_00774(murC) |
FPHO: | SHINM1_017230(murC) |
RTT: | RTTH1527_01160(murC) |
RTB: | RTB9991CWPP_01165(murC) |
WPP: | DEJ70_03575 DEJ70_04205 |
WDM: | EJB00_02625 EJB00_03520 |
WES: | JKF54_01485 JKF54_05815 |
WEM: | CAI20_04040 CAI20_05575 |
WEP: | JSQ73_000735 JSQ73_006270 |
WEE: | LOK48_00400 LOK48_00965 |
SSIV: | MJ631_03040 MJ631_03090 |
WEX: | M1L25_000571 M1L25_000686 |
WEK: | M1L26_000456 M1L26_000571 |
WEND: | M3L71_05300 M3L71_05625 |
RBS: | RHODOSMS8_01895(murC) |
SMEL: | SM2011_c01867(murC) |
SFD: | USDA257_c44990(murC) |
SAME: | SAMCFNEI73_Ch2461(murC) |
AGR: | AGROH133_07427(murC) |
AVV: | RvVAT039_03510(murC) |
AVF: | RvVAR031_24190(murC) |
ASAL: | CFBP5507_09270(murC) |
ALEG: | CFBP4996_08805(murC) |
REC: | RHECIAT_CH0002997(murC) |
REL: | REMIM1_CH02894(murC) |
REP: | IE4803_CH03071(murC) |
REI: | IE4771_CH03109(murC) |
RTR: | RTCIAT899_CH11355(murC) |
RGA: | RGR602_CH02495(murC) |
RPHA: | AMC79_CH03009(murC) |
RLW: | RlegWSM1455_14370(murC) |
NEN: | NCHU2750_14850(murC) |
LAS: | CLIBASIA_04990(murC) |
BRC: | BCCGELA001_09980(murC) |
BSEP: | HAP48_0002775(murC) |
BCAN: | BcanWSM471_29040(murC) |
VGO: | GJW-30_1_01845(murC) |
BHS: | BM1374165_01163(murC) |
BBK: | BARBAKC583_0946(murC) |
BTX: | BM1374166_01517(murC) |
BEZ: | NCTC12898_01029(murC) |
MAQU: | Maq22A_c12410(murC) |
MTUN: | MTUNDRAET4_1811(murC) |
FIL: | BN1229_v1_3987(murC) |
FIY: | BN1229_v1_3974(murC) |
BSB: | Bresu_1060 Bresu_2692 |
BRD: | JL11_05565 JL11_15980(murC) |
BNE: | DA69_01700 DA69_10270 |
BRG: | A4249_09915(murC) A4249_10625 |
BRL: | BZG35_13670 BZG35_14655 |
BVC: | CEP68_03455 CEP68_04625 |
BDM: | EQG53_00670 EQG53_07875 |
BRF: | E4M01_03765 E4M01_13130 |
BREV: | E7T10_05140 E7T10_05895 |
BMED: | GYM46_05035 GYM46_11680 |
BND: | KWG56_00980(murC) KWG56_18235 |
BPON: | IFE19_02205 IFE19_11870 |
BGOE: | IFJ75_00455 IFJ75_02525 |
BVIT: | JIP62_05255 JIP62_11785 |
BALB: | M8231_10400 M8231_11250(murC) |
BFQ: | JX001_05630 JX001_06640 |
BRES: | E4341_04435 E4341_05110 |
BREA: | HZ989_12840 HZ989_13900 |
BBUL: | U0030_11345(murC) U0030_12715 |
TSV: | DSM104635_01984(murC_1) DSM104635_02823(murC_2) |
APAH: | KB221_03330 KB221_05485(murC) |
RLI: | RLO149_c025700(murC) |
PHP: | PhaeoP97_00930(murC) |
PPIC: | PhaeoP14_00882(murC) |
SINL: | DSM14862_01101(murC) |
SPSE: | SULPSESMR1_01941(murC) |
RMM: | ROSMUCSMR3_01029(murC) |
LALG: | LentiSH36_01690(murC) |
LVS: | LOKVESSMR4R_01003(murC) |
AALK: | LGT41_0008835(murC) |
HNE: | HNE_1136 HNE_3022(murC) |
CBOT: | ATE48_00440 ATE48_15420(murC) |
NPP: | PP1Y_AT21234 PP1Y_AT7463 |
NPN: | JI59_14365(murC) JI59_18955 |
NRE: | BES08_01845 BES08_09740 |
NOV: | TQ38_011470 TQ38_013850 |
NOT: | C7W88_09800 C7W88_10585 |
NOR: | FA702_00875 FA702_15105 |
NGF: | FRF71_01350 FRF71_10450 |
NDR: | HT578_18990 HT578_20650 |
NOL: | NSDW_17500 NSDW_27310(murC) |
NCP: | U0041_07535(murC) U0041_08465 |
SPHK: | SKP52_14800(murC) SKP52_14895 |
SPHP: | LH20_14510(murC) LH20_14600 |
SMAG: | AN936_12625(murC) AN936_12720 |
SMAZ: | LH19_13905(murC) LH19_14000 |
STER: | AOA14_01925(murC) AOA14_02020 |
SGI: | SGRAN_1457(murC2) SGRAN_1484(murC) |
SPHQ: | BWQ93_00430 BWQ93_00530 |
SPHO: | C3E99_04040 C3E99_04185 |
SPHX: | E5675_06485 E5675_06580 |
SINA: | KNJ79_05950 KNJ79_06045 |
SPHU: | SPPYR_0892 SPPYR_0912(murC) |
STAX: | MC45_09240(murC) MC45_10930 |
SPHI: | TS85_10030(murC) TS85_16170 |
SSAN: | NX02_00745(murC) NX02_24390 |
SNJ: | A7E77_03225 A7E77_03510 |
SPAN: | AWL63_05780 AWL63_11860(murC) |
SKR: | BRX40_08050 BRX40_19170 |
SPLM: | BXU08_07570 BXU08_09950 |
SPHC: | CVN68_07985 CVN68_11920 |
SPHF: | DM480_09925 DM480_11465 |
SPHA: | D3Y57_10470 D3Y57_15975 |
SPAU: | DRN02_008075 DRN02_009985 |
SLUT: | H9L13_05380 H9L13_12055 |
SRHI: | H9L12_07390 H9L12_08935 |
SLAN: | GV829_12930 GV829_13360 |
SSED: | H9L14_09215 H9L14_10335 |
SPAP: | H3Z74_01610 H3Z74_04730 |
SXA: | FMM02_03765 FMM02_08850 |
SPAI: | FPZ24_03220 FPZ24_11180 |
SPII: | G7077_02355 G7077_10285 |
SSIN: | G7078_08820 G7078_09985 |
SSAU: | H8M03_02040 H8M03_11055 |
SARI: | H5J25_01365 H5J25_12495 |
SSUA: | FPZ54_07545 FPZ54_11120 |
SBIN: | SBA_ch1_35000(murC) |
SDON: | M9980_06915(murC) M9980_08850 |
SSAG: | KV697_05685(murC) KV697_08125 |
SPAG: | sphantq_01056(murC) |
CIJ: | WG74_07625(murC) WG74_13370 |
SPHG: | AZE99_09845 AZE99_10675(murC) |
SFLA: | SPHFLASMR4Y_00090(murC) SPHFLASMR4Y_00286(murC) |
SPHY: | CHN51_11990 CHN51_12965 |
SPHL: | LPB140_06135 LPB140_09415 |
SLAA: | EUU25_06660 EUU25_09845 |
BMAA: | T8S45_03110 T8S45_07955(murC) |
SPHJ: | BSL82_07075 BSL82_08185 |
SPZR: | G5C33_06265 G5C33_08420 |
PALG: | HFP57_01110 HFP57_15485 |
PARP: | HFP51_02450 HFP51_14620 |
PARJ: | J4G78_05655 J4G78_15395 |
PHAO: | HF685_06775 HF685_11855 |
ACOB: | P0Y56_02980 P0Y56_06965(murC) |
SSAA: | RPR59_11705(murC) RPR59_12525 |
SPHS: | ETR14_15510 ETR14_19470 |
SFLV: | IC614_06665 IC614_07695 |
AEP: | AMC99_01387 AMC99_01864 |
ALH: | G6N82_00005 G6N82_12700 |
ARUE: | QQX03_06770 QQX03_10000(murC) |
ALTN: | LBX01_09300(murC) LBX01_12975 |
AAY: | WYH_00236(murC_1) WYH_01343(murC_2) |
AMX: | AM2010_439 AM2010_657 |
PMAS: | NCF86_02250(murC) NCF86_06695 |
ANH: | A6F65_01479(murC_1) A6F65_02260(murC_2) |
ADO: | A6F68_01504(murC_1) A6F68_02000(murC_2) |
TFV: | IDJ81_07770 IDJ81_10345 |
CNA: | AB433_11880 AB433_13530(murC) |
CMAN: | A9D14_10210 A9D14_10410 |
ERY: | CP97_07890 CP97_12095 |
EGN: | BMF35_a0177 BMF35_a1669 |
EFV: | CHH26_07190 CHH26_12230 |
QCI: | NCF85_02410(murC) NCF85_07300 |
QSP: | L1F33_05965(murC) L1F33_10600 |
QSO: | IRL76_02130 IRL76_06810 |
QAR: | K3148_01620(murC) K3148_13330 |
QGE: | K3136_00480 K3136_12245(murC) |
QPS: | K3166_05195 K3166_09015(murC) |
QXI: | K3162_00485 K3162_11675(murC) |
ELQ: | Ga0102493_11194 Ga0102493_112298 |
ERK: | CD351_06130 CD351_11210 |
ERR: | DVR09_06335 DVR09_10930 |
ERF: | FIU90_05910(murC1) FIU90_11275(murC2) |
EMV: | HQR01_01400 HQR01_10670 |
PNS: | A9D12_08910 A9D12_13175 |
ERYT: | KDC96_03710 KDC96_08825 |
ERYZ: | F7D01_00770 F7D01_02950 |
PORL: | BG023_111292 BG023_112144 |
PHZ: | CHX26_07050 CHX26_11960 |
POT: | E2E27_10240 E2E27_15555 |
PORC: | CBR61_06570 CBR61_11685 |
NTD: | EGO55_01315 EGO55_13260 |
CAEN: | K5X80_09240 K5X80_15130(murC) |
AFLV: | QQW98_02185(murC) QQW98_10605 |
MAGX: | XM1_1061 XM1_1510(murC) |
MAGN: | WV31_13480 WV31_15590 |
HFL: | PUV54_04455 PUV54_10540(murC) |
HPO: | HMPREF4655_20976(murC) |
HPX: | HMPREF0462_0788(murC) |
HPYA: | HPAKL117_02945(murC) |
HPYK: | HPAKL86_04525(murC) |
HCL: | NCTC13205_00031(murC) |
HSH: | NHP194022_08580(murC) |
HPUL: | NCTC13154_01589(murC) |
CJV: | MTVDSCj20_1060(murC) |
CFV: | CFVI03293_0612(murC) |
CAMP: | CFT03427_0619(murC) |
CCOC: | CCON33237_0424(murC) |
CLR: | UPTC16701_1130(murC) |
CLM: | UPTC16712_1163(murC) |
CAMR: | CAQ16704_1149(murC) |
CHV: | CHELV3228_0735(murC) |
CPIN: | CPIN18020_1608(murC) |
CAMZ: | CVIC12175_1032(murC) |
GEC: | GEO60473_24860(murC) |
GBN: | GEOBRER4_04900(murC) |
PPOR: | JCM14722_12440(murC) |
MFB: | MFUL124B02_32645(murC) |
CCRO: | CMC5_019550(ddl) CMC5_065360 |
MAI: | MICA_1417 MICA_1899(murC) |
BAZ: | BAMTA208_14655(murC) |
BAE: | BATR1942_12705(murC) |
BSON: | S101395_01379(murC) |
BTHR: | YBT1520_24775(murC) |
BTHU: | YBT1518_25980(murC) |
BFD: | NCTC4823_01294(murC) |
BACI: | B1NLA3E_17460(murC) |
PARG: | PspKH34_06870(murC) |
BLEN: | NCTC4824_01341(murC) |
SAX: | USA300HOU_1730(murC) |
SUQ: | HMPREF0772_11413(murC) |
SUX: | SAEMRSA15_16480(murC) |
SUF: | SARLGA251_16300(murC) |
SAUT: | SAI1T1_2012770(murC) |
SAUJ: | SAI2T2_1012790(murC) |
SAUK: | SAI3T3_1012770(murC) |
SAUQ: | SAI4T8_1012780(murC) |
SAUV: | SAI7S6_1012790(murC) |
SAUW: | SAI5S5_1012740(murC) |
SAUX: | SAI6T6_1012750(murC) |
SAUY: | SAI8T7_1012780(murC) |
SDP: | NCTC12225_01259(murC) |
SPIC: | SAMEA4384060_1219(murC) |
SSH: | NCTC13712_01732(murC) |
SSIM: | SAMEA4384339_1623(murC) |
SSTE: | SAMEA4384403_1002(murC) |
LMOC: | LMOSLCC5850_1670(murC) |
LMW: | LMOSLCC2755_1614(murC) |
LMX: | LMOSLCC2372_1670(murC) |
LMZ: | LMOSLCC2482_1665(murC) |
LMON: | LMOSLCC2376_1563(murC) |
LMOS: | LMOSLCC7179_1579(murC) |
LMOO: | LMOSLCC2378_1622(murC) |
LMOY: | LMOSLCC2479_1668(murC) |
LMOT: | LMOSLCC2540_1684(murC) |
LMOA: | LMOATCC19117_1616(murC) |
LGZ: | NCTC10812_01606(murC) |
GMO: | NCTC11323_01500(murC) |
GHA: | NCTC10459_01535(murC) |
BAYD: | BSPP4475_13995(murC) |
PPM: | PPSC2_19425(murC) PPSC2_27940 |
PPQ: | PPSQR21_039140(murC) |
PRZ: | GZH47_09880 GZH47_27425 |
PLYC: | GXP70_20255 GXP70_22965 |
PTHI: | NDS46_07550(murC) NDS46_15365(murC) |
PDY: | QJQ58_06530(murC) QJQ58_14790(murC) |
PSPN: | L1F29_14385(murC) L1F29_22055(murC) |
PNK: | AASFL403_01820(murC) |
PKP: | SK3146_05664(murC_1) SK3146_06034(murC_2) |
COHN: | KCTCHS21_19260(murC) |
TUM: | CBW65_02255 CBW65_19170 |
TAB: | CIG75_04360(murC) CIG75_10265(murC) |
EFF: | skT53_00500(murC) skT53_15600 |
SPYM: | M1GAS476_0356(murC) |
SPH: | MGAS10270_Spy0287(murC) |
SPI: | MGAS10750_Spy0285(murC) |
SPJ: | MGAS2096_Spy0308(murC) |
SPK: | MGAS9429_Spy0290(murC) |
STG: | MGAS15252_0318(murC) |
STZ: | SPYALAB49_000322(murC) |
SNV: | SPNINV200_13590(murC) |
SNC: | HMPREF0837_11755(murC) |
SPNE: | SPN034156_04210(murC) |
SPNU: | SPN034183_13320(murC) |
SPNM: | SPN994038_13210(murC) |
SPNO: | SPN994039_13220(murC) |
SMC: | SmuNN2025_0392(murC) |
SDG: | SDE12394_01925(murC) |
SGG: | SGGBAA2069_c17760(murC) |
SCP: | HMPREF0833_11045(murC) |
SVB: | NCTC12167_00276(murC) |
SMEN: | SAMEA4412692_1344(murC) |
SFER: | NCTC12278_01533(murC) |
SCAI: | NCTC12191_00156(murC) |
SPSU: | NCTC13786_01689(murC) |
SPOC: | NCTC10925_01466(murC) |
SAUP: | NCTC3168_01209(murC) |
SURN: | NCTC13766_00279(murC) |
SVF: | NCTC3166_01539(murC) |
SMIE: | NCTC11169_01377(murC) |
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