Entry |
|
Name |
biotin---[methylcrotonoyl-CoA-carboxylase] ligase;
biotin-[methylcrotonoyl-CoA-carboxylase] synthetase;
biotin-beta-methylcrotonyl coenzyme A carboxylase synthetase;
beta-methylcrotonyl coenzyme A holocarboxylase synthetase;
holocarboxylase-synthetase
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Class |
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
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Sysname |
biotin:apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] ligase (AMP-forming)
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Reaction(IUBMB) |
ATP + biotin + apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] = AMP + diphosphate + [3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] [RN: R04604]
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Reaction(KEGG) |
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Substrate |
ATP [CPD: C00002];
biotin [CPD: C00120];
apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] [CPD: C04827]
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Product |
AMP [CPD: C00020];
diphosphate [CPD: C00013];
[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] [CPD: C04801]
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History |
EC 6.3.4.11 created 1972
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Pathway |
|
Orthology |
K01942 | biotin---protein ligase |
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Genes |
» show all
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Reference |
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Authors |
Hopner T, Knappe J. |
Title |
[Synthesis of biotin in beta-methylcrotonyl-CoA-carboxylase by holocarboxylase synthetase] |
Journal |
Biochem Z 342:190-206 (1965) |
Other DBs |
ExplorEnz - The Enzyme Database: | 6.3.4.11 |
ExPASy - ENZYME nomenclature database: | 6.3.4.11 |
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