KEGG ENZYME: 6.3.4.11

ENZYME: 6.3.4.11

Entry

EC 6.3.4.11                 Enzyme

Name

biotin---[methylcrotonoyl-CoA-carboxylase] ligase;
biotin-[methylcrotonoyl-CoA-carboxylase] synthetase;
biotin-beta-methylcrotonyl coenzyme A carboxylase synthetase;
beta-methylcrotonyl coenzyme A holocarboxylase synthetase;
holocarboxylase-synthetase

Class

Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases

Sysname

biotin:apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] ligase (AMP-forming)

Reaction(IUBMB)

ATP + biotin + apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] = AMP + diphosphate + [3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] [RN:R04604]

Reaction(KEGG)

R04604;
(other) R01074 R05145

Substrate

ATP [CPD:C00002];
biotin [CPD:C00120];
apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] [CPD:C04827]

Product

AMP [CPD:C00020];
diphosphate [CPD:C00013];
[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] [CPD:C04801]

History

EC 6.3.4.11 created 1972

Pathway

ec00780

Biotin metabolism

ec01100

Metabolic pathways

Orthology

K01942

biotin---protein ligase

Genes

HSA:	3141(HLCS)

PTR:	473989(HLCS)

PPS:	100985942(HLCS)

GGO:	101135438(HLCS)

PON:	100457062(HLCS)

PPYG:

129022436(HLCS)

NLE:	100599352(HLCS)

HMH:	116482569(HLCS)

SSYN:

129482980(HLCS)

MCC:	694733(HLCS)

MCF:	102133502(HLCS)

MTHB:

126951553

MNI:	105472658(HLCS)

CSAB:

103218635(HLCS)

CATY:

105575421(HLCS)

PANU:

101013764(HLCS)

TGE:	112621212(HLCS)

MLEU:

105544999(HLCS)

RRO:	104679174(HLCS)

RBB:	108543829(HLCS)

TFN:	117095757(HLCS)

PTEH:

111525767(HLCS)

CANG:

105520341(HLCS)

CJC:	100388312(HLCS)

SBQ:	101045875(HLCS)

CIMI:

108302561(HLCS)

ANAN:

105712556(HLCS)

CSYR:

103254137(HLCS)

MMUR:

105881298(HLCS)

LCAT:

123630731(HLCS)

PCOQ:

105806888(HLCS)

OGA:	100962733(HLCS)

MMU:	110948(Hlcs)

MCAL:

110311917(Hlcs)

MPAH:

110329965(Hlcs)

RNO:	288240(Hlcs)

MCOC:

116086167(Hlcs)

ANU:	117718128(Hlcs)

ASYL:

127665619(Hlcs)

MUN:	110560965(Hlcs)

CGE:	100752840(Hlcs)

MAUA:

101825408(Hlcs)

PROB:

127227544(Hlcs)

PLEU:

114700373(Hlcs)

MORG:

121461742(Hlcs)

MFOT:

126513580

AAMP:

119825079(Hlcs)

NGI:	103750093 103750102

HGL:	101722847(Hlcs)

CPOC:

100716230(Hlcs)

CCAN:

109693415(Hlcs)

DORD:

105994008(Hlcs)

DSP:	122114310(Hlcs)

DMER:

138832524(Hlcs)

PLOP:

125351465(Hlcs)

NCAR:

124992503

MMMA:

107136469(Hlcs)

ITI:	101956444(Hlcs)

OCU:

100349035

OPI:	101523312(HLCS)

TUP:	102498435(HLCS)

CFA:	478412(HLCS)

CLUD:

112661919(HLCS)

VVP:	112911371(HLCS)

VLG:	121479299(HLCS)

NPO:	129502090(HLCS)

AML:	100464483(HLCS)

UMR:	103673150(HLCS)

UAH:	113260107(HLCS)

UAR:	123802684(HLCS)

ELK:

111155824

LLV:

125094597

MPUF:

101682919(HLCS)

MNP:	132012389(HLCS)

MLK:	131825361(HLCS)

NVS:	122908298(HLCS)

ORO:	101363115 101368585(HLCS)

EJU:	114218940(HLCS)

ZCA:	113917206(HLCS)

MLX:	118018863(HLCS)

NSU:	110570073(HLCS)

LWW:	102735699(HLCS)

FCA:	101100992(HLCS)

PYU:	121035949(HLCS)

PCOO:

112850350(HLCS)

PBG:	122491180(HLCS)

PVIV:

125174960(HLCS)

LRUF:

124526095

LGF:	123610592(HLCS)

AJU:

106966985

PTG:	102964368(HLCS)

PPAD:

109249774(HLCS)

PUC:

125920748

PLEZ:

122229396(HLCS)

HHV:	120229710(HLCS)

BTA:	534247(HLCS)

BOM:	102276987(HLCS)

BIU:	109561544(HLCS) 109563420

BBUB:

102407054(HLCS)

BBIS:

104984888(HLCS)

CHX:	102179708(HLCS)

OAS:	101109588(HLCS)

BTAX:

128056219(HLCS)

CSUM:

138079548(HLCS)

ODA:	120880672(HLCS)

MREE:

136173765(HLCS)

OVR:	110123114(HLCS)

MBEZ:

129549140(HLCS)

SSC:	100515056(HLCS)

CFR:	102520771(HLCS)

CBAI:

105070401(HLCS)

CDK:	105089839(HLCS)

VPC:	102538594(HLCS)

BACU:

103015318(HLCS)

BMUS:

118894378(HLCS)

LVE:	103086335(HLCS)

OOR:	101281208(HLCS)

LALB:

132521334(HLCS)

GMF:	115865814(HLCS)

DLE:	111163877(HLCS)

PCAD:

102981930(HLCS) 114485348

PSIU:

116753145(HLCS)

PPHC:

136122117(HLCS)

NASI:

112408673(HLCS)

ECB:	100061132(HLCS)

EPZ:	103550461(HLCS)

EAI:	106831403(HLCS)

MYB:	102263271(HLCS)

MYD:	102765347(HLCS)

MMYO:

118675452(HLCS)

MLF:	102440948(HLCS)

MDT:	132229868(HLCS)

MYUM:

139004300(HLCS)

PKL:	118723485(HLCS)

EFUS:

103289910(HLCS)

MNA:	107543170(HLCS)

DRO:	112305753(HLCS)

SHON:

118983280(HLCS)

AJM:	119035750(HLCS)

PDIC:

114490841(HLCS)

PHAS:

123828033(HLCS)

MMF:	118617233(HLCS)

PPAM:

129074398(HLCS)

HAI:	109391229(HLCS)

RFQ:	117034459(HLCS)

PALE:

102889335(HLCS)

PGIG:

120598588(HLCS)

PVP:	105295819(HLCS)

RAY:	107499284(HLCS)

MJV:	108398522(HLCS)

TOD:	119257083(HLCS)

SARA:

101557365(HLCS)

SFUM:

130028704(HLCS)

SETR:

126025590(HLCS)

LAV:	100666961(HLCS)

TMU:

101340265

ETF:	101656844(HLCS)

DNM:	101417266(HLCS)

MDO:	100012694(HLCS)

GAS:	123242479(HLCS)

SHR:	100914711(HLCS)

AFZ:

127553814

PCW:	110214863(HLCS)

TVP:	118837860(HLCS)

PBRV:

138142045(HLCS)

MLAO:

141506824(HLCS)

OAA:	120637974(HLCS)

TACU:

119945254(HLCS)

GGA:	418516(HLCS)

PCOC:

116242079(HLCS)

MGP:	100544537(HLCS)

CJO:	107323321(HLCS)

TPAI:

128076321(HLCS)

LMUT:

125684740(HLCS)

NMEL:

110402806(HLCS)

APLA:

101793696(HLCS)

ACYG:

106036092(HLCS)

CATA:

118247748(HLCS)

AFUL:

116493828(HLCS)

TGU:	105758711(HLCS)

LSR:	110469057(HLCS)

SCAN:

108961921(HLCS)

PMOA:

120511785(HLCS)

OTC:	121333572(HLCS)

PRUF:

121364465(HLCS)

ATRC:

139591498(HLCS)

GFR:	102039791(HLCS)

FAB:	101811028(HLCS)

OMA:	130262854(HLCS)

PHI:	102113505(HLCS)

PMAJ:

107202517(HLCS)

CCAE:

111928640(HLCS)

CCW:	104696775(HLCS)

CBRC:

103617033(HLCS)

ACOE:

138108054(HLCS)

ETL:	114070498(HLCS) 114071342 114072950

ZLE:	135444066(HLCS)

ACHL:

103801071(HLCS)

SVG:	106855735(HLCS)

MMEA:

130580001(HLCS)

HRT:

120747874

SATI:

136358224(HLCS)

CCIC:

134058134(HLCS)

FPG:	101921711(HLCS)

FCH:	102053171(HLCS)

CCRI:

104161458

NNT:

104401697

SHAB:

115603744(HLCS)

ACUN:

113482863(HLCS)

TALA:

104367106(HLCS)

ACHC:

115343774(HLCS)

HALD:

104312696

HLE:	104839811(HLCS)

AGEN:

126053138

HHAR:

128144882(HLCS)

GCL:

127024079

CSTI:

104553000

LDI:

104354894

MNB:	103771810(HLCS)

DPUB:

104304944(HLCS)

PPUS:

135180180(HLCS)

AVIT:

104273981

BRHI:

104491950

EGZ:	104128244(HLCS)

NNI:	104020182(HLCS)

PCRI:

104037019

PCAO:

104049438(HLCS)

PADL:

103920277(HLCS)

AFOR:

103901992(HLCS)

FGA:

104072328

GSTE:

104253174

CBOY:

140644045(HLCS)

CLV:	102093696(HLCS)

CNIC:

135991941(HLCS)

MUI:	104543252(HLCS)

PGUU:

104460842

PLET:

104623306(HLCS)

EHS:

104513294

CMAC:

104484074

CUCA:

104064784(HLCS)

TEO:	104375606(HLCS)

BREG:

104634557

OHA:	104327716(HLCS)

ACAR:

104519611(HLCS)

CPEA:

104391198(HLCS)

CVF:	104292009(HLCS)

RTD:	128910822(HLCS)

CRID:

134520401(HLCS)

AAM:	106494968(HLCS)

AROW:

112971860(HLCS)

NPD:	112959086(HLCS)

TGT:	104572491 104573238

DNE:	112996144(HLCS)

SCAM:

104139431(HLCS)

ASN:	102384054(HLCS)

AMJ:	102565173(HLCS)

CPOO:

109305810(HLCS)

GGN:	109302688(HLCS)

PSS:	102452909(HLCS)

CMY:	102944554(HLCS)

CCAY:

125643891(HLCS)

DCC:	119859772(HLCS)

CPIC:

101934162(HLCS)

TST:

117888291

CABI:

116834913(HLCS)

MRV:	120405524(HLCS)

ACS:	100562676(hlcs)

ASAO:

132771858(HLCS)

PVT:	110076819(HLCS)

SUND:

121924901(HLCS)

PBI:	103067600(HLCS)

PMUR:

107296825(HLCS)

CTIG:

120320378(HLCS)

TSR:	106540930(HLCS)

PGUT:

117679791(HLCS)

PCAE:

139316677(HLCS)

APRI:

131199126(HLCS)

PTEX:

113436240(HLCS)

NSS:	113409904(HLCS)

VKO:	123028983(HLCS)

PMUA:

114596081(HLCS)

PRAF:

128413015(HLCS)

ZVI:	118085627(HLCS)

HCG:	128350247(HLCS)

GJA:	107116049(HLCS)

STOW:

125432224(HLCS)

EMC:	129325853(HLCS)

XLA:	108707861(hlcs.L)

XTR:	100492512(hlcs)

NPR:	108785966(HLCS)

RTEM:

120927941(HLCS)

ACAT:

141129271(HLCS)

BBUF:

120994491(HLCS)

BGAR:

122930793 122932980

DTC:	141097463(HLCS)

PWL:	138248704(HLCS)

MUO:	115469498(HLCS)

GSH:	117362813(HLCS)

DRE:	337784(hlcs)

SRX:	107747605(hlcs)

SANH:

107676487(hlcs)

SGH:	107572952(hlcs)

CCAR:

109097448(hlcs)

CAUA:

113054772

CGIB:

128013317 128020687 128020931

PTET:

122333922(hlcs)

LROH:

127171952(hlcs)

GRF:	141299445(hlcs)

OMC:	131548399(hlcs)

PPRM:

120478423(hlcs)

MAMB:

125262586(hlcs)

CIDE:

127521941

CERY:

137028454(hlcs)

MASI:

127432710

TROS:

130545865(hlcs)

TDW:	130411613(hlcs)

MANU:

129446353(hlcs)

PDAB:

135746321(hlcs)

IPU:

108277209

IFU:	128620758(hlcs)

PHYP:

113543599(hlcs)

SMEO:

124393475(hlcs)

TFD:	113645674(hlcs)

TVC:	132863142(hlcs)

CGAR:

128505711(hlcs)

NGRA:

132873503(hlcs)

TRN:	134332292(hlcs)

AMEX:

103022047(hlcs)

CMAO:

118824639(hlcs)

EEE:	113581671(hlcs)

CHAR:

105902089(hlcs)

SPIL:

134080175(hlcs)

TRU:	101061285(hlcs)

TFS:	130537374(hlcs)

TNG:	GSTEN00016316G001

LCO:	104937128(hlcs)

NCC:	104958355(hlcs)

TBEN:

117469538(hlcs)

CGOB:

115019227(hlcs)

PGEO:

117458563(hlcs)

GACU:

117553008(hlcs)

EMAC:

134872728(hlcs)

ELY:	117266071(hlcs)

EFO:	125897955(hlcs)

PLEP:

121952414(hlcs)

SLUC:

116058207(hlcs)

ECRA:

117955796(hlcs)

ESP:	116700468(hlcs)

PFLV:

114567320(hlcs)

GAT:	120822345(hlcs)

PPUG:

119215381(hlcs)

AFB:	129113453(hlcs)

CLUM:

117742450(hlcs)

PSWI:

130211670(hlcs)

CANA:

137802991(hlcs)

CVE:	137880137(hlcs)

MSAM:

119895079(hlcs)

SCHU:

122888245(hlcs)

SPUL:

138594647(hlcs)

LMIX:

132988371(hlcs)

ALAT:

119031285(hlcs)

ASTR:

137605884(hlcs)

MZE:	101470218(hlcs)

ONL:	100710097(hlcs)

OAU:	116335319(hlcs)

OLA:	101169801(hlcs)

OML:	112142766(hlcs)

CSAI:

133459538(hlcs)

XMA:	102227719(hlcs)

XCO:	114153743(hlcs)

XHE:	116727964(hlcs)

PRET:

103476369(hlcs)

PFOR:

103130816

PLAI:

106941182

PMEI:

106906378

GAF:	122845331(hlcs)

PPRL:

129354000(hlcs)

CVG:	107100031(hlcs)

CTUL:

119791207(hlcs)

GMU:	124876218(hlcs)

NFU:	107386340(hlcs)

KMR:

108247189

ALIM:

106534551(hlcs)

NWH:	119420346(hlcs)

EJA:	138207637(hlcs)

BFRE:

138614877(hlcs)

MCEP:

125021309(hlcS)

CSEM:

103395776(hlcs)

POV:	109642009(hlcs)

SSEN:

122779783(hlcs)

SSOE:

131458724(hlcs)

HHIP:

117774943(hlcs)

HSP:	118122116(hlcs)

PPLT:

128456994(hlcs)

SMAU:

118300730(hlcs)

LCF:

108900070

SDU:	111234598(hlcs)

SLAL:

111653972(hlcs)

XGL:	120802396(hlcs)

HCQ:	109519595(hlcs)

SSCV:

125986647(hlcs)

SBIA:

133491389(hlcs)

PEE:	133415707(hlcs)

PTAO:

133467365(hlcs)

BPEC:

110170317(hlcs)

ENY:	140361242(hlcs)

MALB:

109972019(hlcs)

BSPL:

114869291(hlcs)

SJO:	128371873(hlcs)

SSCO:

133994128(hlcs)

GMH:	115546761(hlcs)

SASA:

106567688(hlcs)

STRU:

115148757(hlcs)

OTW:	112257954(hlcs)

OMY:	110537572(hlcs)

OGO:	123999580(hlcs)

ONE:	115105454(hlcs)

OKI:

109892826

OKE:	118390677 118391077(hlcs)

OMM:

135548695

OCLA:

139423181

SALP:

111980678(hlcs)

SNH:	120030996(hlcs)

CCLU:

121551977

ELS:	105023991(hlcs)

OEP:	134039288(hlcs)

SFM:	108936248(hlcs)

PKI:	111855789 111858423(hlcs)

AANG:

118235918(hlcs)

AROT:

135263322(hlcs)

CCOG:

133134123(hlcs)

LOC:	102690116(hlcs)

PSPA:

121302870(hlcs)

ARUT:

117406319 117407164

PSEX:

120523272(hlcs)

LCM:	102347440(HLCS)

CMK:	103188738(hlcs)

RTP:	109936700(hlcs)

CPLA:

122555338(hlcs)

HOC:	132821165(hlcs)

LERI:

129703015(hlcs)

HAKA:

140727518(hlcs)

PMRN:

116952927(HLCS)

LRJ:	133354263(HLCS)

BFO:	118422809 118423079

BBEL:

109464518

CIN:

100179742

SCLV:

120336784

SPU:

577740

LPIC:

129259703

AJJ:

139962523

APLC:

110986169

ARUN:

117296532

AAMU:

139947097

AFIL:

140157417

SKO:

100369411

PFLL:

139142158

DME:	Dmel_CG14670(Hcs)

DER:

6552203

DSI:	Dsimw501_GD19789(Dsim_GD19789)

DYA:	Dyak_GE25471

DSR:

110177272

DPO:

6897601

DPE:

6591344

DMN:

108155261

DWI:

6647187

DGR:

6563879

DMO:	Dmoj_GI23080

DAZ:

108614926

DNV:

108656012

DHE:

111603564

CCAT:

101453066

BOD:

106618089

BDR:

105225980

RZE:

108360017

AOQ:

129241539

ALUD:

128865050

TDA:

119680235

SCAC:

106086242

LCQ:

111680170

LSQ:

119606134

CVJ:	135949540(Hcs)

GFS:

119642639

ECOE:

129943491

CLON:

129608152

HIS:

119660409

AGA:

1281690

ACOZ:

120949731

AARA:

120896139

AMER:

121603568

ASTE:

118505163

AMAP:

126556905

AFUN:

125762356

AMOU:

128309757

AMRS:

128710227

ACOS:

131259110

AAG:

5571860

AALB:

109404810

ASUA:

134217547

CQU:	CpipJ_CPIJ007071 CpipJ_CPIJ007072

CPII:

120422427

CBRI:

134827609

CNS:

116339785

BCOO:

119074323

LLL:

129788565

PPAP:

129800692

AME:

411759

ACER:

107996086

ALAB:

122719799

ADR:

102675016

AFLR:

100872695

BIM:

100741269

BBIF:

117216160

BVK:

117231240

BVAN:

117155110

BHUN:

126872904

BTER:

100642502

BAFF:

126923588

BPYO:

122574687

BPAS:

132913253

FVI:

122527804

CCAL:

113464824

OBB:

114881255

MGEN:

117224851

NMEA:

116427632

CGIG:

122396269

SOC:

105208017

MPHA:

105832368

AEC:

105150986

ACEP:

105619994 105625408

ACOC:

108688049

MZT:	108723798(Hcs)

PBAR:

105427000

VEM:

105570280

COBS:

139104873(Hcs)

TLN:	139810950(Hcs)

HST:

105187433

DQU:

106752243

CFO:

105254823

FEX:

115245250

PMEC:

138933490(Hcs)

LHU:	105676227(Hcs)

PGC:

109853482

OBO:

105284641

PCF:

106785970

PFUC:

122519663

VPS:

122630628

VCRB:

124424283

VVE:

124950477

NVI:

100120765

CSOL:

105362029

TPRE:

106659272

LHT:

122509053

LBD:

127289881

MDL:

103574421

CGLO:

123269121

CTYP:

141527501(Hcs)

FAS:

105273724

DAM:

107038805

AGIF:

122856527

VCAN:

122413677

CCIN:

107265728

DSM:

124409941

NPT:	124216402(Hcs)

NFB:

124181541

NLO:

107220495

NVG:

124303826

AROA:

105690535

TCA:

100141937

TMOL:

138129253(Hcs)

DPA:

109541261

ESIM:

136417998(Hcs)

EFOR:

136342532(Hcs)

SOY:

115877088

AGRG:

126748915

CSET:

123319879

HAXR:

123675586

AGB:

108907126

LDC:

111507580

DVV:

126880020

NVL:

108566076

APLN:

108744963

PPYR:

116161516

OTU:

111419464

BMOR:

101743517

BMAN:

114239389 114249541

MSEX:

115448234

DPL:	KGM_204685

BANY:

112047377

MJU:

123876691

NIQ:

126776565

VCD:

124538847

MCIX:

123663996

PMAC:

106715388

PPOT:

106110370

PXU:

106116842

BPHI:

137920286(Hcs)

PRAP:

110993032

PBX:

123709651

PNAP:

125054105

ZCE:

119829075

CCRC:

123700865

LSIN:

126970506

AAGE:

121735948

HAW:

110377217

HZE:

124640782

TNL:

113499624

SLIU:

111348888

OFU:

114359388

ONU:

135081876

ATRA:

106131591

GMW:

113520244

PGW:

126379869

LGLY:

125228010

CSTB:

134755946

CFUM:

141439158(Hcs)

CFEL:

113383669

CCRN:

123298076

API:

100166501

DNX:

107172306

AGS:

114132498

RMD:

113551631

ACOO:

126843220

DVT:

126900875

BTAB:

109033441

CLEC:

106662760

HHAL:

106678476

NLU:	111048036 111050202 111058010

HVI:

124360713

MQU:

128993152

PHU:	Phum_PHUM492490

FOC:

113208798

TPAL:

117650062

ZNE:

110833334

CSEC:

111863940

PAME:

138698698(Hcs)

BROR:

134537355

IEL:

124168760

HAMR:

139688193(Hcs)

FCD:

110853379

DPX:	DAPPUDRAFT_309177

DMK:

116918782

HAME:

121871525

EAF:

111714793

LSM:	121120070(Hcs)

DSV:

119466650

RSAN:

119376304

RMP:

119176469

VDE:

111247532

VJA:

111262869

GOE:

100897371

TUT:

107366528

DPTE:

113790808

DFR:

124496674

CSCU:

111640237

CVS:	136971810(Hcs)

PTEP:

107438304

ABRU:

129956860

SDM:

118194372

LPOL:

106461093 106469546

NAI:	NECAME_13444

LOA:	LOAG_17932

HRO:	HELRODRAFT_65278

LGI:	LOTGIDRAFT_171251

PVUL:

126820301

PCAN:

112565926

LSAX:

138961785

BGT:

106068018

GAE:

121372513

HRF:

124117548

HRJ:

124260194

HASI:

137259780

HCRA:

139461253

CRG:

105332906

CANU:

128180210

CVN:

111135439

OED:

125658692

MYI:

110445704

PMAX:

117339376

AIRR:

138334899

MMER:

123552941

RPHI:

132740984

DPOL:

127852785

MAEA:

128238575

OBI:	106879777 106880135

OSN:	115232536 115232587

LJP:

135471718

LAK:

106176354

SMM:	Smp_153150

SHX:	MS3_00002752

OVI:	T265_13178

EGL:

EGR_07298

LLON:

135488253

NVE:

5512817

EPA:

110242401

ATEN:

116291329

ADF:

107339212

MCAZ:

138054530

MFOO:

137996564

PDAM:

113671831

SPIS:

111340632

DGT:

114537726

XEN:	124441389 124441538 124441541 124441869 124442559 124442932

HMG:

105849906

HSY:

130644438

RES:

135685686

AQU:

100632425

ATH:	AT1G37150(HCS2) AT2G25710(HCS1)

ALY:	9314944 9329987

CRB:	17888619 17889810

CSAT:

104703109 104714038 104752205 104752216

EUS:	EUTSA_v10004827mg EUTSA_v10027838mg

BRP:

103852453

BNA:	106368386 106392404 106409576 125585745

BOE:	106316290 106324724

RSZ:	108805431 108830160 130501420

THJ:

104817066

CPAP:

110816651

CIT:

102613353

CIC:	CICLE_v10001583mg

PVY:

116132147

MINC:

123203292 123206093 123229157

TCC:

18592271

GRA:

105770129

GHI:	107922700 107942037

GAB:

108450088

HSYR:

120154372 120176365 120180396

DZI:	111312328 111315616

EGR:	104450472 120286096

RARG:

115737215

GMX:	100813650 100818402

GSJ:	114410456 114415379

PVU:

137821516

VRA:

106761009

VAR:

108330832

VUN:

114162520

VUM:

124845440

CCAJ:

109794594

APRC:

113873178

MTR:

11411288

TPRA:

123896894

CAM:

101507301

PSAT:

127084121

VVO:	131627382 131641727

LJA:

130735961

ADU:

107460788

AIP:

107606089

AHF:	112706108 112764050

LANG:

109340049

PCIN:

129294455

QSA:	O6P43_015225

FVE:

101294231

AANS:

126784571

RCN:

112170520

PPER:

18789279

PMUM:

103332920

PAVI:

110753343

PDUL:

117626156

MDM:	103401855 103421290

MSYL:

126603611 126632037

PXB:	103933707 103956690 103956969

PCOX:

137718475 137742224

ZJU:

107407500

MNT:

21403054

CSAV:

115723218

CSV:

101206408

CMO:

103489963

BHJ:

120085048

MCHA:

111011837

CMAX:

111487622

CMOS:

111458666

CPEP:

111780897 111808204

RCU:	8260803 8274130

MEAN:

126656452

JCU:

105638886

HBR:

110665565

MESC:

110609471

POP:	7460934 7495112

PEU:	105116743 105127853

PALZ:

118029356 118041751

PNZ:	133690846 133693685

JRE:

109013665

CILL:

122310739

CAVE:

132184356

AGLU:

133854275

QSU:

112037475

QLO:

115960411

TWL:

120008484

VVI:

100248922

VRI:

117907121

SLY:

101252547

SPEN:

107003210

SOT:

102584525

SSTN:

125844903

SDUL:

129903254 129903298

CANN:

107850582 107866583

LBB:

132627044

NTA:	107787843 107819232

NSY:

104238135

NTO:

104085554

NAU:

109240668

INI:	109160079 109177408 109183075 109183459

ITR:	116027229 116027249

SIND:

105176554

OEU:	111377897 111383765

EGT:

105974439

SSPL:

121786473 121811335

SMIL:

131011958

SHIS:

125197468 125221333

APAN:

127246467 127249831

PEBU:

140819584

HAN:

110865661

ECAD:

122590750

LSV:	111893663 111915583

CCAV:

112507572

DCR:	108196570 108196611

CSIN:

114266663 114315283

RVL:

131307514

AEW:

130776395

DLT:	127799179 127808369

BVG:

104885223

SOE:

110795054

CQI:	110725327 110730819

ATRI:

130809897

MOF:

131162440

MING:

122080726

TSS:

122662409

PSOM:

113346420 113356494

OSA:

4328417

OBR:

102717040

OGL:

127761251

BDI:	100835520 100844888

ATS:

109776075

TDC:	119315816 119324192

TAES:

123132409 123136485 123143975

TUA:

125516143

LPER:

127307896

LRD:	124691197 124691754

SBI:

8074691

ZMA:

103626660

MFLO:

136462754 136471168

SITA:

101752965 101769375

SVS:	117836506 117864159

PVIR:

120661515

PHAI:

112875356

PAUA:

133922620

TANG:

140760846

PDA:

103719623

EGU:

105049052

MUS:

135586607

ZOF:

122047656

DCT:

110102880

PEQ:

110038416

AOF:

109831799

MSIN:

131242542

ACAK:

137938761

NCOL:

116261881

ATR:

18423244

CJF:

131029578

SMO:	SELMODRAFT_80973 SELMODRAFT_88773

PPP:

112286816

CRE:	CHLRE_09g406000v5 CHLRE_12g508852v5

VCN:	VOLCADRAFT_120018

MNG:

MNEG_3981

CSL:	COCSUDRAFT_18259

CVR:	CHLNCDRAFT_135977 CHLNCDRAFT_26827

APRO:

F751_5965

OLU:	OSTLU_119606(hcs)

OTA:	OT_ostta02g02000

MIS:	MICPUN_72068

MPP:	MICPUCDRAFT_6647

CME:	CYME_CMC080C

SCE:	YDL141W(BPL1)

SEUB:

DI49_0933

SPAO:

SPAR_D00970

AGO:	AGOS_ADR085W

ERC:

Ecym_8066

KLA:	KLLA0_F05049g

KMX:	KLMA_60514(BPL1)

LTH:	KLTH0H02024g

VPO:	Kpol_1019p23

ZRO:	ZYRO0F05940g

CGR:	2889255(GVI51_I03531)

NCS:	NCAS_0A13910(NCAS0A13910)

NDI:	NDAI_0A02120(NDAI0A02120)

TPF:	TPHA_0A03060(TPHA0A03060)

TBL:	TBLA_0F02180(TBLA0F02180)

TGB:	HG536_0B04920

TDL:	TDEL_0C02310(TDEL0C02310)

KAF:	KAFR_0B01050(KAFR0B01050)

KNG:	KNAG_0C03960(KNAG0C03960)

ZMK:	HG535_0E04840

SLUD:

SCDLUD_000269

DHA:	DEHA2A13750g

PIC:	PICST_69676(BPL1)

PGU:	PGUG_01114

SPAA:

SPAPADRAFT_48797

LEL:	PVL30_002335(BPL1)

LBG:	92207224(LODBEIA_P20280)

CAL:	CAALFM_CR10620CA(CaO19.7645)

CTP:	CTRG_05783

COT:	CORT_0A05280 CORT_0D00250

CDU:	CD36_35420

CTEN:

18248928(BPL1)

CLU:	CLUG_02270

CLUS:

A9F13_02g00264

CAUR:

CJI96_0005147

ASAU:

88172704(PUMCH_001639)

PPA:	PAS_chr3_0569

PKZ:	C5L36_0B05860

BNN:	FOA43_002895

BBRX:

BRETT_005194

OPA:	HPODL_02585

YLI:	2912036(YALI2_E01146g)

SLB:	AWJ20_1398(BPL1)

NCR:

NCU05516

NTE:	NEUTE1DRAFT124604(NEUTE1DRAFT_124604)

SMP:	10807355(SMAC4_00725)

PAN:	PODANSg2869

PBEL:

QC761_403290(BPL1)

PPSD:

QC762_403290(BPL1)

PPSP:

QC763_403290(BPL1)

PPSA:

QC764_403290(BPL1)

TTT:	THITE_2110501

MTM:	MYCTH_2119403 MYCTH_2119478

CTHR:

CTHT_0044660

RTHE:

98126609(VTJ83DRAFT_5372)

MGR:

MGG_00436

PPEI:

PpBr36_08732

PGRI:

PgNI_08915

TMN:	UCRPA7_1182

SSCK:

SPSK_02214

FGR:	FGSG_08329

FPU:	FPSE_09477

FPOA:

FPOAC1_004402

FVN:	FVRRES_04912

FVR:	FVEG_02363

FOX:	FOXG_03496

NHE:	NECHADRAFT_36078

FFC:	NCS54_00370100

FKR:	NCS57_00375400

FMU:	J7337_008705

TRE:	TRIREDRAFT_77714

TRR:	M419DRAFT_24638

TATV:

25784141(TrAtP1_008469)

TASP:

36607621(TrAFT101_002933)

MAW:	19249106(BPL1_1)

MAJ:

MAA_02354

MBRN:

26239941(BPL1)

PCHM:

VFPPC_01307

CMT:

CCM_05319

AMUS:

LMH87_011121

PLJ:	28884721(PLICBS_005936)

PTKZ:

JDV02_008649(BPL1)

VAL:	VDBG_09198

VDA:	VDAG_07355

CFJ:	CFIO01_12603

CLUP:

CLUP02_16719

CHIG:

CH63R_06486

CDET:

87947867(CDEST_11367)

SAPO:

SAPIO_CDS6266

ELA:	UCREL1_3426

PFY:	PFICI_10037

SSL:	SS1G_04467

BFU:	BCIN_01g05670(Bcbpl1)

MBE:

MBM_09693

PSCO:

LY89DRAFT_451641

GLZ:	GLAREA_00139

ANI:	ANIA_06055

AFM:	AFUA_2G09550

ACT:	ACLA_081340

NFI:	NFIA_085040

AOR:	AO090011000708

ANG:	An16g06410

AFV:	AFLA_008108

ALUC:

AKAW2_70524A(BPL1)

ACHE:

ACHE_40684A(BPL1)

APUU:

APUU_11146S(BPL1)

PCS:	N7525_004424

PDP:	PDIP_65150

POU:	POX_f07849

TMF:	EYB26_004782

TRG:	TRUGW13939_01850

CIM:	CIMG_07858

CPW:	9693336(BPL1)

URE:	UREG_02182

ABE:

ARB_05148

TVE:

TRV_07820

PBL:	PAAG_06513

PBN:	PADG_00464

AJE:	HCAG_08683

BGH:	BDBG_06963

PNO:	SNOG_08427

PTE:

PTT_11266

PTRR:

6346849(PtrM4_146620)

BZE:	COCCADRAFT_84592

BSC:	COCSADRAFT_39903

BOR:	COCMIDRAFT_90241

AALT:

CC77DRAFT_1024071

ADAC:

96080346(ACET3X_000024)

ARAB:

EKO05_0005124

ZTR:	MYCGRDRAFT_67807

PFJ:	MYCFIDRAFT_46146

FFU:	CLAFUR5_10752

CBET:

CB0940_06452

BCOM:

BAUCODRAFT_37668

NPA:	UCRNP2_2382

TML:	GSTUM_00004427001

SPO:	2540476(bpl1)

SOM:	SOMG_01070(bpl1)

CNE:

CNC00800

CNB:

CNBC6470

CNG:	CNAG_01565

CGI:	CGB_C1330W

CDEU:

CNBG_9440

CDEC:

89988246(IAS62_001471)

CTEG:

91988605(I308_101747)

CBAS:

91981791(I312_101743)

CDEP:

91085118(L203_100904)

KMG:	30162798(I203_101347)

KNE:	92179657(IAR55_002398)

KDJ:	28966605(I303_102887)

KBI:	30205207(I302_102119)

KPIN:

30171270(I206_102551)

KSH:	87954778(IL334_002647)

KER:	91102617(V865_003815)

TMS:	TREMEDRAFT_40864

TASA:

A1Q1_02988

CCAC:

CcaHIS019_0100680(BPL1)

TVS:	TRAVEDRAFT_74836

DSQ:	DICSQDRAFT_136396

PCO:	PHACADRAFT_253991

SHS:	STEHIDRAFT_146851

HIR:	HETIRDRAFT_147935

PSQ:	PUNSTDRAFT_59339

ADL:	AURDEDRAFT_111555

FME:	FOMMEDRAFT_74436

GTR:	GLOTRDRAFT_65526

RSX:	RhiXN_10869

LBC:	LACBIDRAFT_317063

CCI:	CC1G_15548

ABP:	AGABI1DRAFT114677(AGABI1DRAFT_114677)

ABV:	AGABI2DRAFT226601(AGABI2DRAFT_226601)

MRR:	Moror_6357

E1B28_006469

SCM:	SCHCO_02597546(SCHCODRAFT_02597546)

CPUT:

CONPUDRAFT_124809

SLA:	SERLADRAFT_355394

WSE:	WALSEDRAFT_59378

WIC:	J056_004070

UMA:	UMAG_03839

PFP:	PFL1_06449

SGRA:

EX895_001269

MGL:

MGL_0053

MRT:

MRET_1269

MSYM:

MSY001_1290

PGR:	PGTG_14205

PTRC:

PtA15_9A431

PSTR:

Pst134EA_021178

MLR:	MELLADRAFT_69028

RIE:	OCT59_018828

DDI:	DDB_G0289035(hlcs3)

DPP:	DICPUDRAFT_18614

DFA:	DFA_05534(hlcs3)

PIF:	PITG_12194

PSOJ:

PHYSODRAFT_486526

SPAR:

SPRG_09434

GTT:	GUITHDRAFT_144527

» show all

Reference

1 [PMID:5867144]

Authors

Hopner T, Knappe J.

Title

[Synthesis of biotin in beta-methylcrotonyl-CoA-carboxylase by holocarboxylase synthetase]

Journal

Biochem Z 342:190-206 (1965)

Other DBs

ExplorEnz - The Enzyme Database:

6.3.4.11

IUBMB Enzyme Nomenclature:

6.3.4.11

ExPASy - ENZYME nomenclature database:

6.3.4.11

BRENDA, the Enzyme Database:

6.3.4.11

CAS:	37318-68-6

All links

Gene (1130)   
   MGENES (285)   
   RefGene (845)   
Protein sequence (133)   
   UniProt (116)   
   SWISS-PROT (5)   
   RefSeq(pep) (12)   
DNA sequence (109)   
   RefSeq(nuc) (15)   
   GenBank (48)   
   EMBL (46)   
Protein domain (6)   
   InterPro (6)   
All databases (1378)   

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