KEGG   ENZYME: 6.3.4.12
Entry
EC 6.3.4.12                 Enzyme                                 

Name
glutamate---methylamine ligase;
gamma-glutamylmethylamide synthetase
Class
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
Sysname
L-glutamate:methylamine ligase (ADP-forming)
Reaction(IUBMB)
ATP + L-glutamate + methylamine = ADP + phosphate + N5-methyl-L-glutamine [RN:R01585]
Reaction(KEGG)
R01585
Substrate
ATP [CPD:C00002];
L-glutamate [CPD:C00025];
methylamine [CPD:C00218]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
N5-methyl-L-glutamine [CPD:C03153]
History
EC 6.3.4.12 created 1972
Orthology
K01949  glutamate---methylamine ligase
Genes
GAI: IMCC3135_28060(glnT)
TSN: W908_01950
THIN: CRN91_08145(glnT)
MLN: A9174_29115
MCI: Mesci_5156
MOP: Mesop_5739
MAM: Mesau_05234
MAMO: A6B35_11075
MESW: A9K65_028265
MESM: EJ066_15675(glnT)
MESP: C1M53_18730(glnT)
MHUA: MCHK_0827(glnT)
MJR: EB229_29695(glnT)
MERD: EB233_25740(glnT)
AAK: AA2016_5807
AMIH: CO731_05434(glnT)
PHT: BLM14_24665
RPOD: E0E05_05945(glnT)
SMK: Sinme_3421
SMQ: SinmeB_3196
SMX: SM11_chr3561(glnT)
SMI: BN406_03224(glnT)
SMEG: C770_GR4Chr0097
SMEL: SM2011_c02613(glnT)
SMER: DU99_00490
SMD: Smed_3294 Smed_6005
RHI: NGR_c14410(glnT)
SFH: SFHH103_06333(glnT)
SIX: BSY16_5797(glnT)
SAME: SAMCFNEI73_pC1024
EAK: EKH55_4303
ARA: Arad_8367(glnT)
ATF: Ach5_36150(glnA)
AVI: Avi_5752(glnA)
AGR: AGROH133_12302
AGC: BSY240_3620(glnT)
ARO: B0909_19475(glnT)
REC: RHECIAT_PA0000334(glnT)
REL: REMIM1_PD00440(glnT)
REP: IE4803_PA00370(glnT)
REI: IE4771_PC00383(glnT)
RLT: Rleg2_5641
RLG: Rleg_6578
RLB: RLEG3_05400
RLU: RLEG12_01965
RTR: RTCIAT899_PC09295(glnT)
RHL: LPU83_pLPU83c0694(glnT)
RGA: RGR602_PC01860(glnT)
RHN: AMJ98_PD00425(glnT)
RPHA: AMC79_PB00339(glnT)
RHX: AMK02_PE00432(glnT)
RHK: Kim5_PB00401(glnT)
REZ: AMJ99_PC00426(glnT)
RJG: CCGE525_22845(glnT)
RHR: CKA34_31840(glnT)
BRA: BRADO5882(glnA)
BBT: BBta_1945(glnA)
RPB: RPB_1135
BVV: BHK69_09835
TRB: HB776_20420(glnT)
XAU: Xaut_4698
AZC: AZC_1499
SNO: Snov_0455
STAR: G3545_13135(glnT)
LNE: FZC33_23790(glnT)
ANC: GBB76_17685(glnT)
APRA: G3A50_15290(glnT)
MEA: Mex_1p1553
MDI: METDI2327
MEX: Mext_1659
MCH: Mchl_1941
MPO: Mpop_1572
MZA: B2G69_15955
MRD: Mrad2831_4807
META: Y590_07820
MAQU: Maq22A_c07630(glnA)
METD: C0214_09530(glnT) C0214_27320(glnT)
METX: A3862_04395
METS: DK389_06155(glnT)
MMES: MMSR116_29790(glnT)
MSL: Msil_2635
MTUN: MTUNDRAET4_2822(glnT) MTUNDRAET4_3084
MLG: CWB41_02760(glnT) CWB41_16065(glnT)
BBAR: RHAL1_02575(glnT)
HDN: Hden_0515
HDT: HYPDE_25078
HMC: HYPMC_4366(gmas)
HNI: W911_11235
FIL: BN1229_v1_1169(glnT)
FIY: BN1229_v1_1168(glnT)
PLEO: OHA_1_03153(glnT)
MEY: TM49_12285
MCG: GL4_0799
HDI: HDIA_3398(glnT)
NOH: G5V57_07095(glnT)
METG: HT051_11880(glnT)
SIL: SPO1573(glnT)
RHP: LPB142_05665
RDE: RD1_4250(glnT)
RLI: RLO149_c005820(glnT)
RPON: G3256_12400(glnT)
PAMI: JCM7686_pAMI6p105
PYE: A6J80_01560(glnT)
PZH: CX676_01700(glnT)
PAMN: pAMV1p0109(gmaS)
DSH: Dshi_1867(glnT)
OAR: OA238_c26820
LMD: METH_18430
LEJ: ETW24_17950(glnT)
LAQU: R2C4_19755(glnT)
RED: roselon_03567
PTP: RCA23_c23640(glnA3)
CID: P73_0133
CEH: CEW89_17265(glnT)
MALG: MALG_00923
RHC: RGUI_3209
DAA: AKL17_0252
YAN: AYJ57_19000
TPRO: Ga0080559_TMP4880 Ga0080559_TMP4892
SPSE: SULPSESMR1_03830(glnT)
SULZ: C1J03_14650(glnT)
SULI: C1J05_06630(glnT)
PABY: Ga0080574_TMP1115 Ga0080574_TMP4713
RMM: ROSMUCSMR3_00030(glnT)
ROK: RAK1035_2880
RID: RIdsm_02435(glnT)
ROM: EI983_08250(glnT)
ROH: FIU89_08615(glnT) FIU89_17915(glnA3)
RBG: BG454_15455(glnT)
GEH: HYN69_07415(glnT)
TAW: EI545_08515(glnT)
PPRU: FDP22_15455(glnT)
PAED: G5B38_09610(glnT)
MALU: KU6B_39960
PAMO: BAR1_12125(glnT)
FAQ: G5B39_16775(glnT)
SSAN: NX02_15580
RDI: CMV14_00745(glnT)
GTI: FXF46_11725(glnT)
GBE: GbCGDNIH1_2110
GBH: GbCGDNIH2_2110
GBC: GbCGDNIH3_2110
GBS: GbCGDNIH4_2110
GXL: H845_1584 H845_92
KEU: S101446_00798(glnA)
KSC: CD178_01529(glnT)
AACE: A0U92_02370
SHUM: STHU_53950(glnT)
SVC: STVA_53790(glnT)
RPM: RSPPHO_02176(glnA1)
AZL: AZL_a09540(glnA)
TII: DY252_08035(glnT)
HTQ: FRZ44_30250
HADH: FRZ61_17270
PUB: SAR11_1316(glnT)
PEG: E5R92_06670(glnT)
APC: HIMB59_00013170
APM: HIMB5_00009560
APB: SAR116_1707
FAL: FRAAL1887(glnIII)
CYB: CYB_1005(glnA-1)
SYNE: Syn6312_3383
SYNP: Syn7502_02094
SYU: M744_04820
SYNC: CB0101_01845(glnT)
CGC: Cyagr_1005
CYI: CBM981_0307(glnT)
DSL: Dacsa_3567
CMP: Cha6605_0263
LEN: LEP3755_41240
LET: O77CONTIG1_00575(glnT_1)
LBO: LBWT_8910
HHG: XM38_027690(glnA_1)
PSER: ABRG53_0397(glnA)
THEU: HPC62_14825(glnT)
GLP: Glo7428_3065
ENN: FRE64_06535(glnT)
CYN: Cyan7425_0282
PLS: VT03_09265(glnT)
SOH: D1869_05950(glnT)
 » show all
Reference
1  [PMID:5800436]
  Authors
Kung HF, Wagner C.
  Title
Gamma-glutamylmethylamide. A new intermediate in the metabolism of methylamine.
  Journal
J Biol Chem 244:4136-40 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 6.3.4.12
IUBMB Enzyme Nomenclature: 6.3.4.12
ExPASy - ENZYME nomenclature database: 6.3.4.12
BRENDA, the Enzyme Database: 6.3.4.12
CAS: 37318-69-7

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Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (19442)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (188)   
   KEGG MGENES (16270)   
   RefGene (2983)   
Protein sequence (115)   
   UniProt (113)   
   SWISS-PROT (2)   
DNA sequence (124)   
   GenBank (62)   
   EMBL (62)   
Protein domain (5)   
   InterPro (5)   
All databases (19695)   

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