KEGG   ENZYME: 6.3.4.12
Entry
EC 6.3.4.12                 Enzyme                                 

Name
glutamate---methylamine ligase;
gamma-glutamylmethylamide synthetase
Class
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
Sysname
L-glutamate:methylamine ligase (ADP-forming)
Reaction(IUBMB)
ATP + L-glutamate + methylamine = ADP + phosphate + N5-methyl-L-glutamine [RN:R01585]
Reaction(KEGG)
R01585
Substrate
ATP [CPD:C00002];
L-glutamate [CPD:C00025];
methylamine [CPD:C00218]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
N5-methyl-L-glutamine [CPD:C03153]
History
EC 6.3.4.12 created 1972
Orthology
K01949  glutamate---methylamine ligase
Genes
GAI: IMCC3135_28060(glnT)
TSN: W908_01950
THIN: CRN91_08145(glnT)
MLN: A9174_29115
MCI: Mesci_5156
MOP: Mesop_5739
MAM: Mesau_05234
MAMO: A6B35_11075
MESW: A9K65_028265
MESM: EJ066_15675(glnT)
MESP: C1M53_18730(glnT)
MHUA: MCHK_0827(glnT)
MJR: EB229_29695(glnT)
MERD: EB233_25740(glnT)
AMIH: CO731_05434(glnT)
RPOD: E0E05_05945(glnT)
SMX: SM11_chr3561(glnT)
SMI: BN406_03224(glnT)
SMEL: SM2011_c02613(glnT)
SMER: DU99_00490
RHI: NGR_c14410(glnT)
SFH: SFHH103_06333(glnT)
SIX: BSY16_5797(glnT)
ARA: Arad_8367(glnT)
ATF: Ach5_36150(glnA)
AVI: Avi_5752(glnA)
AGC: BSY240_3620(glnT)
ARO: B0909_19475(glnT)
REC: RHECIAT_PA0000334(glnT)
REL: REMIM1_PD00440(glnT)
REP: IE4803_PA00370(glnT)
REI: IE4771_PC00383(glnT)
RLG: Rleg_6578
RTR: RTCIAT899_PC09295(glnT)
RHL: LPU83_pLPU83c0694(glnT)
RGA: RGR602_PC01860(glnT)
RHN: AMJ98_PD00425(glnT)
RPHA: AMC79_PB00339(glnT)
RHX: AMK02_PE00432(glnT)
RHK: Kim5_PB00401(glnT)
REZ: AMJ99_PC00426(glnT)
RJG: CCGE525_22845(glnT)
RHR: CKA34_31840(glnT)
BRA: BRADO5882(glnA)
BBT: BBta_1945(glnA)
RPB: RPB_1135
TRB: HB776_20420(glnT)
XAU: Xaut_4698
AZC: AZC_1499
SNO: Snov_0455
STAR: G3545_13135(glnT)
LNE: FZC33_23790(glnT)
ANC: GBB76_17685(glnT)
APRA: G3A50_15290(glnT)
MDI: METDI2327
MEX: Mext_1659
MCH: Mchl_1941
MPO: Mpop_1572
META: Y590_07820
MAQU: Maq22A_c07630(glnA)
METD: C0214_09530(glnT) C0214_27320(glnT)
METS: DK389_06155(glnT)
MMES: MMSR116_29790(glnT)
MSL: Msil_2635
MLG: CWB41_02760(glnT) CWB41_16065(glnT)
BBAR: RHAL1_02575(glnT)
HDN: Hden_0515
HMC: HYPMC_4366(gmas)
FIL: BN1229_v1_1169(glnT)
FIY: BN1229_v1_1168(glnT)
PLEO: OHA_1_03153(glnT)
MCG: GL4_0799
HDI: HDIA_3398(glnT)
NOH: G5V57_07095(glnT)
METG: HT051_11880(glnT)
SIL: SPO1573(glnT)
RDE: RD1_4250(glnT)
RLI: RLO149_c005820(glnT)
RPON: G3256_12400(glnT)
PYE: A6J80_01560(glnT)
PZH: CX676_01700(glnT)
PAMN: pAMV1p0109(gmaS)
DSH: Dshi_1867(glnT)
LEJ: ETW24_17950(glnT)
LAQU: R2C4_19755(glnT)
PTP: RCA23_c23640(glnA3)
CID: P73_0133
CEH: CEW89_17265(glnT)
MALG: MALG_00923
RHC: RGUI_3209
SPSE: SULPSESMR1_03830(glnT)
SULZ: C1J03_14650(glnT)
SULI: C1J05_06630(glnT)
RMM: ROSMUCSMR3_00030(glnT)
RID: RIdsm_02435(glnT)
ROM: EI983_08250(glnT)
ROH: FIU89_08615(glnT) FIU89_17915(glnA3)
RBG: BG454_15455(glnT)
GEH: HYN69_07415(glnT)
TAW: EI545_08515(glnT)
PPRU: FDP22_15455(glnT)
PAED: G5B38_09610(glnT)
MALU: KU6B_39960
PAMO: BAR1_12125(glnT)
FAQ: G5B39_16775(glnT)
SSAN: NX02_15580
RDI: CMV14_00745(glnT)
GTI: FXF46_11725(glnT)
KEU: S101446_00798(glnA)
KSC: CD178_01529(glnT)
SHUM: STHU_53950(glnT)
SVC: STVA_53790(glnT)
RPM: RSPPHO_02176(glnA1)
AZL: AZL_a09540(glnA)
TII: DY252_08035(glnT)
PUB: SAR11_1316(glnT)
PEG: E5R92_06670(glnT)
FAL: FRAAL1887(glnIII)
CYB: CYB_1005(glnA-1)
SYNC: CB0101_01845(glnT)
CYI: CBM981_0307(glnT)
LET: O77CONTIG1_00575(glnT_1)
LBO: LBWT_8910
HHG: XM38_027690(glnA_1)
PSER: ABRG53_0397(glnA)
THEU: HPC62_14825(glnT)
ENN: FRE64_06535(glnT)
PLS: VT03_09265(glnT)
SOH: D1869_05950(glnT)
 » show all
Reference
1  [PMID:5800436]
  Authors
Kung HF, Wagner C.
  Title
Gamma-glutamylmethylamide. A new intermediate in the metabolism of methylamine.
  Journal
J Biol Chem 244:4136-40 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 6.3.4.12
IUBMB Enzyme Nomenclature: 6.3.4.12
ExPASy - ENZYME nomenclature database: 6.3.4.12
BRENDA, the Enzyme Database: 6.3.4.12
CAS: 37318-69-7

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