KEGG ENZYME: 6.3.4.12

ENZYME: 6.3.4.12

Entry

EC 6.3.4.12                 Enzyme

Name

glutamate---methylamine ligase;
gamma-glutamylmethylamide synthetase

Class

Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases

Sysname

L-glutamate:methylamine ligase (ADP-forming)

Reaction(IUBMB)

ATP + L-glutamate + methylamine = ADP + phosphate + N5-methyl-L-glutamine [RN:R01585]

Reaction(KEGG)

R01585

Substrate

ATP [CPD:C00002];
L-glutamate [CPD:C00025];
methylamine [CPD:C00218]

Product

ADP [CPD:C00008];
phosphate [CPD:C00009];
N5-methyl-L-glutamine [CPD:C03153]

History

EC 6.3.4.12 created 1972

Orthology

K01949

glutamate---methylamine ligase

Genes

BRA:	BRADO5882(glnA)

BBT:	BBta_1945(glnA)

RPB:

RPB_1135

RHOR:

ONR75_09135(glnT)

RHOL:

RBJ75_10275(glnT)

TRB:	HB776_20420(glnT)

TARD:

RSO67_14080(glnT)

BVV:	BHK69_09835

BOSE:

RMR04_25040(glnT)

XAU:

Xaut_4698

XDI:	EZH22_24765(glnT)

AZC:

AZC_1499

STAR:

G3545_13135(glnT)

SNO:

Snov_0455

ANC:	GBB76_17685(glnT)

APRA:

G3A50_15290(glnT)

APOL:

K9D25_00540(glnT)

AQI:	J5J86_15970(glnT)

MEA:	Mex_1p1553

MDI:

METDI2327

MEX:

Mext_1659

MCH:

Mchl_1941

MPO:

Mpop_1572

MZA:	B2G69_15955

METQ:

MSPGM_15920

MRD:	Mrad2831_4807

META:

Y590_07820

MAQU:

Maq22A_c07630(glnA)

METD:

C0214_09530(glnT) C0214_27320(glnT)

METX:

A3862_04395

METS:

DK389_06155(glnT)

MIND:

mvi_52000(glnT)

MOG:	MMB17_10265(glnT)

MECL:

CLZ_07295(glnT)

MFUJ:

ABC766_16075(glnT)

MENI:

GU700_07295(glnT)

MENS:

LOK46_25815(glnT)

MLG:	CWB41_16065(glnT)

BBAR:

RHAL1_02575(glnT)

FIL:	BN1229_v1_1169(glnT)

FIY:	BN1229_v1_1168(glnT)

CMET:

K6K41_10835(glnT)

HDI:	HDIA_3398(glnT)

AUZ:	Sa4125_08460

TSO:

IZ6_30310

RDI:	CMV14_00745(glnT)

SSAN:

NX02_15580

ACIM:

GT370_04425(glnT)

AZL:	AZL_a09540(glnA)

HTQ:	FRZ44_30250

HADH:

FRZ61_17270

» show all

Reference

1 [PMID:5800436]

Authors

Kung HF, Wagner C.

Title

Gamma-glutamylmethylamide. A new intermediate in the metabolism of methylamine.

Journal

J Biol Chem 244:4136-40 (1969)

Other DBs

ExplorEnz - The Enzyme Database:

6.3.4.12

IUBMB Enzyme Nomenclature:

6.3.4.12

ExPASy - ENZYME nomenclature database:

6.3.4.12

BRENDA, the Enzyme Database:

6.3.4.12

CAS:	37318-69-7

All links

Gene (19332)   
   MGENES (16349)   
   RefGene (2983)   
Protein sequence (113)   
   UniProt (111)   
   SWISS-PROT (2)   
DNA sequence (170)   
   GenBank (86)   
   EMBL (84)   
Protein domain (6)   
   InterPro (6)   
All databases (19621)   

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