KEGG   ENZYME: 6.3.4.7Help
Entry
EC 6.3.4.7                  Enzyme                                 

Name
ribose-5-phosphate---ammonia ligase;
5-phosphoribosylamine synthetase;
ribose 5-phosphate aminotransferase;
ammonia-ribose 5-phosphate aminotransferase
Class
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
BRITE hierarchy
Sysname
ribose-5-phosphate:ammonia ligase (ADP-forming)
Reaction(IUBMB)
ATP + ribose 5-phosphate + NH3 = ADP + phosphate + 5-phosphoribosylamine [RN:R01053]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
ribose 5-phosphate [CPD:C00117];
NH3 [CPD:C00014]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
5-phosphoribosylamine [CPD:C03090]
History
EC 6.3.4.7 created 1972
Pathway
ec00230  Purine metabolism
Reference
1  [PMID:5699059]
  Authors
Reem GH.
  Title
Enzymatic synthesis of 5'-phosphoribosylamine from ribose 5-phosphate and ammonia, an alternate first step in purine biosynthesis.
  Journal
J Biol Chem 243:5695-701 (1968)
Other DBs
ExplorEnz - The Enzyme Database: 6.3.4.7
IUBMB Enzyme Nomenclature: 6.3.4.7
ExPASy - ENZYME nomenclature database: 6.3.4.7
BRENDA, the Enzyme Database: 6.3.4.7
CAS: 9082-52-4

DBGET integrated database retrieval system