KEGG   ENZYME: 6.5.1.8
Entry
EC 6.5.1.8                  Enzyme                                 
Name
3'-phosphate/5'-hydroxy nucleic acid ligase;
rtcB (gene name)
Class
Ligases;
Forming phosphoric-ester bonds;
Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
Sysname
poly(ribonucleotide)-3'-phosphate:5'-hydroxy-poly(ribonucleotide) ligase (GMP-forming)
Reaction(IUBMB)
(1) (ribonucleotide)n-3'-phosphate + 5'-hydroxy-(ribonucleotide)m + GTP = (ribonucleotide)n+m + GMP + diphosphate (overall reaction);
(1a) GTP + [RNA ligase]-L-histidine = [RNA ligase]-Ntau-(5'-guanosyl-phosphono)-L-histidine + diphosphate;
(1b) [RNA ligase]-Ntau-(5'-guanosyl-phosphono)-L-histidine + (ribonucleotide)n-3'-phosphate = (ribonucleotide)n-3'-(5'-diphosphoguanosine) + [RNA ligase]-L-histidine;
(1c) (ribonucleotide)n-3'-(5'-diphosphoguanosine) + 5'-hydroxy-(ribonucleotide)m = (ribonucleotide)n+m + GMP;
(2) (ribonucleotide)n-2',3'-cyclophosphate + 5'-hydroxy-(ribonucleotide)m + GTP + H2O = (ribonucleotide)n+m + GMP + diphosphate (overall reaction);
(2a) (ribonucleotide)n-2',3'-cyclophosphate + H2O = (ribonucleotide)n-3'-phosphate;
(2b) GTP + [RNA ligase]-L-histidine = [RNA ligase]-Ntau-(5'-guanosyl-phosphono)-L-histidine + diphosphate;
(2c) [RNA ligase]-Ntau-(5'-guanosyl-phosphono)-L-histidine + (ribonucleotide)n-3'-phosphate = (ribonucleotide)n-3'-(5'-diphosphoguanosine) + [RNA ligase]-L-histidine;
(2d) (ribonucleotide)n-3'-(5'-diphosphoguanosine) + 5'-hydroxy-(ribonucleotide)m = (ribonucleotide)n+m + GMP
Substrate
(ribonucleotide)n-3'-phosphate;
5'-hydroxy-(ribonucleotide)m;
GTP [CPD:C00044];
[RNA ligase]-L-histidine;
[RNA ligase]-Ntau-(5'-guanosyl-phosphono)-L-histidine;
(ribonucleotide)n-3'-(5'-diphosphoguanosine);
(ribonucleotide)n-2',3'-cyclophosphate;
H2O [CPD:C00001]
Product
(ribonucleotide)n+m [CPD:C00046];
GMP [CPD:C00144];
diphosphate [CPD:C00013];
[RNA ligase]-Ntau-(5'-guanosyl-phosphono)-L-histidine;
(ribonucleotide)n-3'-(5'-diphosphoguanosine);
[RNA ligase]-L-histidine;
(ribonucleotide)n-3'-phosphate
Comment
The enzyme is a GTP- and Mn2+-dependent 3'-5' nucleic acid ligase with the ability to join RNA with 3'-phosphate or 2',3'-cyclic-phosphate ends to RNA with 5'-hydroxy ends. It can also join DNA with 3'-phosphate ends to DNA with 5'-hydroxy ends, provided the DNA termini are unpaired [6]. The enzyme is found in members of all three kingdoms of life, and is essential in metazoa for the splicing of intron-containing tRNAs. The reaction follows a three-step mechanism with initial activation of the enzyme by GTP hydrolysis, forming a phosphoramide bond between the guanylate and a histidine residue. The guanylate group is transferred to the 3'-phosphate terminus of the substrate, forming the capped structure [DNA/RNA]-3'-(5'-diphosphoguanosine). When a suitable 5'-OH end is available, the enzyme catalyses an attack of the 5'-OH on the capped end to form a 3'-5' phosphodiester splice junction, releasing the guanylate. When acting on an RNA 2',3'-cyclic-phosphate, the enzyme catalyses an additional reaction, hydrolysing the cyclic phosphate to a 3'-phosphate [9]. The metazoan enzyme requires activating cofactors in order to achieve multiple turnover catalysis [8].
History
EC 6.5.1.8 created 2017
Orthology
K14415  tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase)
Genes
HSA51493(RTCB)
PTR458782(RTCB)
PPS100971358(RTCB)
GGO101144723(RTCB)
PON100439200(RTCB)
NLE100595915(RTCB)
MCC717258(RTCB)
MCF102144880(RTCB)
CSAB103223215(RTCB)
CATY105575770(RTCB)
PANU100137237(RTCB)
TGE112633806(RTCB)
RRO104674734 115892825
RBB108535095(RTCB)
TFN117096551(RTCB)
PTEH111542738(RTCB)
CJC100408961(RTCB)
SBQ101047236
CSYR103257742(RTCB)
MMUR105875630(RTCB)
LCAT123639332(RTCB)
OGA100940565(RTCB)
MMU28088(Rtcb)
MCAL110303293(Rtcb)
MPAH110326155(Rtcb)
RNO362855(Rtcb)
MCOC116076025(Rtcb)
MUN110564848
CGE100753929(Rtcb)
MAUA101835102(Rtcb)
PLEU114703011(Rtcb)
MORG121459520(Rtcb)
AAMP119803681(Rtcb)
NGI103742114(Rtcb)
HGL101717628(Rtcb)
CPOC100734763(Rtcb)
CCAN109698924(Rtcb)
DORD105992111(Rtcb)
DSP122119219(Rtcb)
NCAR124977805 124983604
OCU100346526(RTCB)
OPI101526668(RTCB)
TUP102492731(RTCB)
CFA474524(RTCB)
VVP112929061(RTCB)
VLG121491124(RTCB)
AML100467421(RTCB)
UMR103676455(RTCB)
UAH113256024(RTCB)
UAR123780712(RTCB)
ELK111157565
LLV125107196
MPUF101679710(RTCB)
ORO101385250(RTCB)
EJU114197530(RTCB)
ZCA113921610(RTCB) 113929500
MLX117998764(RTCB)
FCA101090197(RTCB)
PYU121040458(RTCB)
PBG122472671(RTCB)
PTG102966524(RTCB)
PPAD109265475(RTCB)
AJU106971932(RTCB)
HHV120230740(RTCB)
BTA525106(RTCB)
BOM102286278(RTCB)
BIU109559482(RTCB)
BBUB102402412(RTCB)
CHX102189284(RTCB)
OAS101118007(RTCB)
ODA120858612(RTCB)
CCAD122423482(RTCB)
SSC733658(RTCB)
CFR102520545(RTCB)
CBAI105081326(RTCB)
CDK105101076(RTCB)
VPC102540079(RTCB)
BACU102998172(RTCB)
LVE103075690(RTCB)
OOR101279974(RTCB)
DLE111187917(RTCB)
PCAD102996697(RTCB)
PSIU116760870(RTCB)
ECB100054153(RTCB)
EPZ103552701(RTCB)
EAI106838341(RTCB)
MYB102243411(RTCB)
MYD102768836(RTCB)
MMYO118650289(RTCB)
MLF102422686 102425152(RTCB)
MNA107544989(RTCB)
PKL118729871(RTCB)
HAI109382848(RTCB)
DRO112321780(RTCB)
SHON119002191(RTCB)
AJM119060300(RTCB)
PDIC114512937(RTCB)
PHAS123810689(RTCB)
MMF118624405(RTCB)
RFQ117028426(RTCB)
PALE102882315(RTCB)
PGIG120614900(RTCB)
PVP105288296(RTCB)
RAY107512471(RTCB)
MJV108399357(RTCB)
TOD119247324(RTCB)
SARA101544041(RTCB)
LAV100675436(RTCB)
TMU101348587
DNM101438890(RTCB)
MDO100016063(RTCB)
GAS123249317(RTCB)
SHR100928215(RTCB)
PCW110205700(RTCB)
OAA100077731(RTCB)
GGA418064(RTCB)
PCOC116233278(RTCB)
MGP100539950(RTCB)
CJO107314485(RTCB)
NMEL110393529(RTCB)
APLA101795314(RTCB)
ACYG106035776(RTCB)
AFUL116497688(RTCB)
TGU100227339(RTCB)
LSR110483823(RTCB)
SCAN103813204(RTCB)
PMOA120510056(RTCB)
OTC121342406(RTCB)
PRUF121361170(RTCB)
GFR102031778(RTCB)
FAB101819411(RTCB)
PHI102099960(RTCB)
PMAJ107204353(RTCB)
CCAE111931292(RTCB)
CCW104696258(RTCB)
ETL114058867(RTCB)
ZAB102073764(RTCB)
FCH114014219(RTCB)
CLV106145813(RTCB)
EGZ104134155(RTCB)
NNI104020743(RTCB)
PLET104620305(RTCB)
ACUN113482139(RTCB)
TALA104358219(RTCB)
PADL103924541(RTCB)
ACHC115352721(RTCB)
AAM106488831(RTCB)
AROW112964860(RTCB)
NPD112958419(RTCB)
DNE112993961(RTCB)
ASN102379448(RTCB)
AMJ102577238(RTCB)
CPOO109316597(RTCB)
GGN109296091(RTCB)
PSS102463710(RTCB)
CMY102929490(RTCB)
CPIC101948221(RTCB)
TST117881115(RTCB)
CABI116828125(RTCB)
MRV120395289(RTCB)
ACS100554682(rtcb)
PVT110084369(RTCB)
SUND121931899(RTCB)
PBI103063098(RTCB)
PMUR107284725(RTCB)
TSR106539062(RTCB)
PGUT117655319(RTCB)
VKO123028922(RTCB)
PMUA114605101(RTCB)
ZVI118091161(RTCB)
GJA107124178(RTCB)
STOW125435223(RTCB)
XLA108712553(rtcb.S) 779280(rtcb.L)
XTR595066(rtcb)
NPR108789951(RTCB)
RTEM120932858(RTCB)
BBUF121005390(RTCB)
BGAR122928408(RTCB)
DRE406376(rtcb)
SRX107707948 107710072(rtcb)
SANH107662217
SGH107568717(rtcb)
CAUA113048513(rtcb)
PPRM120470912(rtcb)
MAMB125244353(rtcb)
IPU108274978(rtcb)
PHYP113529486(rtcb)
SMEO124392234(rtcb)
TFD113653997(rtcb)
AMEX103036305(rtcb)
EEE113573675(rtcb)
LCO104931389(rtcb)
CGOB115005202(rtcb)
ELY117249062(rtcb)
SLUC116056955(rtcb)
PFLV114550065(rtcb)
GAT120817205(rtcb)
PPUG119211174(rtcb)
MSAM119895992(rtcb)
CUD121505237(rtcb)
ALAT119032503(rtcb)
MZE101478440(rtcb)
ONL100706393(rtcb)
OAU116317958(rtcb)
OLA101164466(rtcb)
OML112157669(rtcb)
XMA102228137(rtcb)
XCO114161262(rtcb)
XHE116736460(rtcb)
PRET103459793(rtcb)
PFOR103129562(rtcb)
PLAI106954101(rtcb)
PMEI106917097(rtcb)
GAF122826777(rtcb)
CVG107081389(rtcb)
CTUL119790567(rtcb)
GMU124883108(rtcb)
NFU107387696(rtcb)
KMR108229103(rtcb)
ALIM106535293(rtcb)
NWH119428203(rtcb)
AOCE111574309(rtcb)
CSEM103382483(rtcb)
POV109647074(rtcb)
SSEN122765795(rtcb)
HHIP117757443(rtcb)
HSP118101368(rtcb)
LCF108882416(rtcb)
SDU111229477(rtcb)
SLAL111671047(rtcb)
XGL120797982(rtcb)
HCQ109532601(rtcb)
BPEC110161894(rtcb)
MALB109967659(rtcb)
BSPL114862520(rtcb)
SASA106593674(rtcb)
OTW121845277(rtcb)
OMY110517212
OGO123995838 124020965
SALP112079181(rtcb)
SNH120036911 120038469
ELS105026520(rtcb)
SFM108931978 108942537
PKI111846996(rtcb)
AANG118218985(rtcb)
LOC102688377(rtcb)
PSPA121318582(rtcb) 121319523
ARUT117414977 117419922
LCM102358373(RTCB)
CMK103181817(rtcb)
RTP109911850(rtcb)
BFO118415876
BBEL109471650
CIN100176177
SCLV120339449
SPU588300
APLC110982862
SKO100377188
DMEDmel_CG9987(RtcB)
DER6549653
DSE6614682
DSIDsimw501_GD24205(Dsim_GD24205)
DYADyak_GE13253
DAN6496870
DSR110181377
DPODpse_GA22169
DPE6597959
DMN108163778
DWI6641666
DGR6566464
DMODmoj_GI14026
DAZ108610312
DNV115563761
DHE111592590
DVI6634217
CCAT101454563
BOD106620720
MDE101891055 101891228
SCAC106090517 106092390
LCQ111684233
LSQ119608634
HIS119652605
AGAAgaP_AGAP008147
ACOZ120958423
AARA120903657
ASTE118513704
AAG5577915
AALB109427583 109621904
CQUCpipJ_CPIJ004874 CpipJ_CPIJ019543
CPII120421999
CNS116349570
BCOO119068512 119070325 119081959 119081978
AME409653
ACER107999015
ALAB122712303
BIM100745965
BBIF117206023
BVK117235536
BVAN117154135
BTER100647213
BPYO122565693
CCAL108632338
OBB114871693
MGEN117218705
NMEA116432234
CGIG122400867
SOC105203762
MPHA105828557
AEC105143294
ACEP105623347
PBAR105432766
VEM105560055
HST105184601
DQU106746563
CFO105250110
FEX115238471
LHU105678651
PGC109855294
OBO105278260
PCF106786206
PFUC122525439
VPS122633440
NVI100123449
CSOL105368627
TPRE106655753
MDL103579776
CGLO123265632
DAM107044565
AGIF122857480
CCIN107271141
TCA658169
DPA109545488
SOY115875559
ATD109605089 109605947
CSET123312961
AGB108912150
LDC111513244
NVL108561811
APLN108733568
PPYR116175431 116177342
OTU111424060
BMOR101739631
BMAN114251546
MSEX115448173 119192346
DPLKGM_206102
BANY112052570
PMAC106710710
PPOT106109375
PXU106128453
PRAP110992677
ZCE119835133
HAW110369919
TNL113508025
SLIU111351644
OFU114350443
PXY105391195
API100160137
DNX107171119
AGS114122803
RMD113553699
BTAB109039845 109042252
DCI103516737 103520176
CLEC106661619
HHAL106689922
NLU111063139
PHUPhum_PHUM545510
FOC113213111
TPAL117639550
ZNE110831184
CSEC111873471
FCD110862618
DPXDAPPUDRAFT_302483
DMK116925670
PVM113809613 113827359
PJA122262152
PCHN125042109
HAME121863241
PCLA123753196
PTRU123519914
HAZT108668705
EAF111701937
LSM121113658
PPOI119108467 119108625
DSV119430974
RSAN119406888
RMP119163378
VDE111249857
VJA111273960
TUT107367363
DPTE113793956
DFR124492694
PTEP107444400
SDM118188163
CELCELE_F16A11.2(rtcb-1)
CBRCBG_22190
BMYBM_BM3402(Bma-rtcb-1)
LOALOAG_16672
NAINECAME_13404
TSPTsp_12314
HROHELRODRAFT_184836
LGILOTGIDRAFT_201648
PCAN112571587
BGT106058009
GAE121369086 121391275
HRF124134124
HRJ124258613
CRG105324932 105342599 117685355
MYI110462262
PMAX117330469
OBI106867593
OSN115212962
LAK106159803
SHXMS3_0015791
OVIT265_03928
EGLEGR_00905
NVE5520396
EPA110248067
ATEN116307330
ADF107331153
AMIL114968749 114969350
PDAM113670692
SPIS111322440 111339434
DGT114521825
XEN124434895
HMG100200632
TADTRIADDRAFT_18395
AQU100635515
CRECHLRE_11g467766v5
VCNVOLCADRAFT_63305
MNGMNEG_5458
CSLCOCSUDRAFT_46227
CVRCHLNCDRAFT_55997
APROF751_2036
OLUOSTLU_25152
OTAOT_ostta10g01920
BPGBathy11g01950
MISMICPUN_59883
MPPMICPUCDRAFT_24370
CMECYME_CME059C
GSLGasu_03500
CCPCHC_T00005284001
ECUECU01_1120
EINEint_011050
EHEEHEL_011020
EROEROM_010940
MBRMONBRDRAFT_24995
SREPTSG_06172
DDIDDB_G0278481
DPPDICPUDRAFT_90903
DFADFA_10051
EHIEHI_169260(177.t00019) EHI_184560(391.t00003)
EDIEDI_022970 EDI_260790
EIVEIN_027210 EIN_098520
PFAPF3D7_1105700
PFHPFHG_01759
PREIPRSY57_1104200
PGABPGSY75_1105700
PYOPY17X_0943700
PCBPCHAS_090310(PC000172.03.0)
PBEPBANKA_0941200
PVVPVVCY_0900510
PKNPKNH_0903300
PVXPVX_090965
PCYPCYB_091270
TANTA10620
TPVTP04_0661
TOTTOT_040000239
BEQBEWA_009420
BBOBBOV_III007770(17.m07681)
BMICBmR1_04g06065
BBIGBBBOND_0306880
TGOTGME49_207450
SMINv1.2.021296.t1(symbB.v1.2.021296.t1)
TPSTHAPSDRAFT_41953
AAFAURANDRAFT_54616
EHXEMIHUDRAFT_194002
GTTGUITHDRAFT_156993
TVATVAG_386070
ECOb3421(rtcB)
ECJJW3384(rtcB)
ECDECDH10B_3595(rtcB)
EBWBWG_3114(rtcB)
ECOKECMDS42_2866(rtcB)
ECEZ4779(rtcB)
ECSECs_4264(rtcB)
ECFECH74115_4729(rtcB)
ETWECSP_4373(rtcB)
ELXCDCO157_4005
EOIECO111_4229(rtcB)
EOJECO26_4508(rtcB)
ECOOECRM13514_4370(rtcB)
ECOHECRM13516_4167(rtcB)
ESLO3K_01960
ESOO3O_23690
ESMO3M_02005
ECKEC55989_3828(rtcB)
ECGE2348C_3665(rtcB)
EOKG2583_4120(rtcB)
ELRECO55CA74_19670
ELHETEC_3670
ECWEcE24377A_3896(rtcB)
EUNUMNK88_4188
ECPECP_3506
ECVAPECO1_3046(rtcB)
ECOAAPECO78_20890
ECXEcHS_A3618(rtcB)
ECMEcSMS35_3701(rtcB)
ECYECSE_3687
ECRECIAI1_3564(rtcB)
ECQECED1_4081(rtcB)
EUMECUMN_3879(rtcB)
ECTECIAI39_3901(rtcB)
EOCCE10_3941(rtcB)
EBRECB_03272(rtcB)
EBLECD_03272(rtcB)
EBEB21_03224(rtcB)
EBDECBD_0321
ECIUTI89_C3921(rtcB)
EIHECOK1_3836(rtcB)
ECZECS88_3809(rtcB)
ECCc4198(rtcB)
ELOEC042_3681(rtcB)
ELNNRG857_16930
ECLEcolC_0293
EKOEKO11_0323
EKFKO11_05680
EABECABU_c38410(rtcB)
EDHEcDH1_0293
EDJECDH1ME8569_3299(rtcB)
ELUUM146_17160
ELWECW_m3678(rtcB)
ELLWFL_17970
ELCi14_3869(rtcB)
ELDi02_3869(rtcB)
ELPP12B_c3521
ELFLF82_2042(rtcB)
ECOLLY180_17540
ECOIECOPMV1_03727(rtcB_2)
EFEEFER_3389(rtcB)
EALEAKF1_ch2543(rtcB)
EMAC1192_14970
ESZFEM44_08055
STMSTM3519(rtcB)
SEOSTM14_4238(rtcB)
SEVSTMMW_35091
SEYSL1344_3486(rtcB)
SEMSTMDT12_C35740
SEJSTMUK_3505(rtcB)
SEBSTM474_3687(rtcB)
SEFUMN798_3822
SETUSTU288_17795
SETCCFSAN001921_22850
SENRSTMDT2_34061(rtcB)
SENDDT104_35031(rtcB)
SENICY43_18290
SEENSE451236_03310
SEISPC_3588(rtcB)
SECSCH_3450(rtcB)
SEHSeHA_C3827(rtcB)
SHBSU5_03994
SENHCFSAN002069_14580
SEEHSEEH1578_03675
SEASeAg_B3720
SENSQ786_17175
SEDSeD_A3890(rtcB)
SEGSG3919(rtcB)
SELSPUL_4060
SEGASPUCDC_4046
SETSEN3345(rtcB)
SENAAU38_17065
SENOAU37_17255
SENVAU39_17260
SENQAU40_19230
SENLIY59_17690
SEECCFSAN002050_24550
SEEBSEEB0189_002275
SEEPI137_19410
SENEIA1_17065
SENCSEET0819_01185
SALZEOS98_01685
SFLSF3443(rtcB)
SFXS4321(rtcB)
SFVSFV_3428(rtcB)
SFESFxv_3759
SFNSFy_4899
SFSSFyv_4972
SFTNCTC1_03724(rtcB_2)
SSNSSON_3552(rtcB)
SBOSBO_3409(rtcB)
SBCSbBS512_E3801(rtcB)
SHQA0259_20860
ERNBFV67_01195
ECLSLI67_002170
ENRH650_16745
ENFAKI40_4685
ESAESA_00065
CSKES15_0387(rtcB)
CSZCSSP291_00295
CSJCSK29544_01350
CCONAFK62_17995
CDMAFK67_18570
CSIP262_00556
CMJAFK66_002000
CUIAFK65_17720
CMWAFK63_00680
CTUCTU_37920(rtcB)
KMIVW41_00645
EAEEAE_08330
EARCCG32330
KLWDA718_02155
CROROD_37281(rtcB)
CAMAF384_22205
CAFAL524_04985
CFARCI104_23480
CIRC2U53_11575
CTELGBC03_06445
CEMLH23_06590
PGELG71_05375
ESCEntcl_0663
KSAC813_13935
KCOBWI95_04155
KOTEH164_20895
KPSEIP581_01350
LAXAPT61_21020
LEIC2U54_06100
LEHC3F35_10465
LEEDVA44_22440
LERGNG29_01110
LEAGNG26_01140
LPNUKQ929_19365
BUFD8682_14750
BFTMNO13_23565
METYMRY16398_53340(rtcB)
KINAB182_23535
PDZHHA33_00565
EBCC2U52_06505
SFWWN53_11365
SFGAV650_06615
SFOZ042_14045
PCTPC1_0404
PCCPCC21_004370
PCVBCS7_02190
PWAPecwa_0487
PPARA8F97_15945
PECW5S_0513
PWSA7983_10470
PPOABJK05_19055
PBRAB5S52_19605
PPUJE2566_02565
PARII2D83_19735
PVZOA04_04960(rtcB)
PPAVLOZ86_19780
DZEDd1591_0013
DDCDd586_0013
EPECI789_19670
PANPPSNIH2_18350
PALHB1H58_06500
PGZC2E15_01265
PCDC2E16_01315
PLUplu4307(rtcB)
PLUMA4R40_21350
PAYPAU_00438
PAKHB0X70_02800
PLUICE143_02785
PVGCRN77_18140
PHAUPH4a_11200
PCOLF1325_04170
PCIBF9282_03965
PPEEI6G31_05335
XBOXBJ1_0417(rtcB)
XBVXBW1_4362(rtcB)
XHOA9255_13475
XBUHGO23_17450
PSIS70_08035
PSXDR96_1573(rtcB)
PSTABGK56_11085
PRGRB151_005160(rtcB_1)
PHEINCTC12003_00520(rtcB_1)
PRQCYG50_13480
PVCG3341_02350
MMKMU9_137
LPVHYN51_02380
PFQQQ39_10280
PRAGEKN56_09165
XCCXCC3883
XCBXC_3970
XCAxcc-b100_4072
XCPXCR_0396
XCVXCV4058
XAXXACM_3836
XACXAC3965
XCIXCAW_00337
XCTJ151_04145
XCJJ158_04098
XCUJ159_04094
XCNJ169_04142
XCWJ162_04099
XCRJ163_04094
XCMJ164_04095
XCFJ172_04135
XFUXFF4834R_chr38310
XAOXAC29_19990
XSASB85_18910
XVEBJD12_10560
XPEBJD13_19235
XPHXppCFBP6546_14695(XppCFBP6546P_14695)
XVAC7V42_20270
XANAC801_19660
SMLSmlt4533
SMTSmal_3893
BUJBurJV3_3940
SMZSMD_4076(rtcB)
STENCCR98_20190
STEMCLM74_20735
STESMG068_20170
SINCDAIF1_40830(rtcB)
SPAQSTNY_R40790
PMEXH4W19_11715
PJPLAG73_19520
LABLA76x_0969(rtcB) LA76x_4435(rtcB)
LAQGLA29479_2186(rtcB) GLA29479_2482(rtcB)
LCPLC55x_0729(rtcB) LC55x_4477(rtcB)
LGULG3211_0665(rtcB) LG3211_4287(rtcB)
LEZGLE_4348 GLE_4681
LEMLEN_0578 LEN_0868(rtcB)
LMBC9I47_2914
LYJFKV23_01830
LSOLGOY17_17080
LAREHIV01_015955
LUMCNR27_11250
LUSE5843_00695
LUGFPZ22_07130
THESFHQ07_09050
TCNH9L16_04600 H9L16_08505
DCSISN74_18375
DKOI596_263
LRZBJI69_07315
LPYFIV34_20810
XBAC7S18_02535
VNIVIBNI_A1840(rtcB)
VCYIX92_17945
PAEPA4583
PAEVN297_4734
PAEIN296_4734
PAUPA14_60650
PAPPSPA7_5225
PAGPLES_49661
PAFPAM18_4676
PNCNCGM2_1011
PAEBNCGM1900_2423
PDKPADK2_24345
PSGG655_24150
PRPM062_24130
PAEPPA1S_24845
PAERPA1R_gp2488
PAEMU769_25105
PAELT223_25365
PAESSCV20265_5212
PAEUBN889_05094
PAEGAI22_09200
PAECM802_4732
PAEOM801_4599
PMYPmen_1193
PREPCA10_09120
PFUWKF707C_8330
PCQPcP3B5_10160(rtcB)
PMUIG4G71_27905
PPGPputGB1_0576
PPTPPS_0526
PPUHB479_03135
PPUNPP4_05660(rtcB)
PPUDDW66_0540
PFVPsefu_3727
PMONX969_01075
PMOTX970_01065
PMOSO165_026685
PPJRK21_04483
PMOLCLJ08_15720
PFLPFL_2304
PPRCPFLCHA0_c23690(rtcB2)
PPROPPC_2345
PFOPfl01_1946(rtcB)
PMANOU5_5751
PTVAA957_02895
PCGAXG94_26015
PMEDE3Z27_11710
PENPSEEN0615
PLULFOB45_07530
PDRH681_04585
PSVPVLB_22560
PKCPKB_4819(rtcB)
PCHEY04_10630
PCZPCL1606_38480
PCPJM49_19275
PALKPSAKL28_05660
PPVNJ69_15900
PSESPSCI_2979
PSEMTO66_11495
PSECCCOS191_4789(rtcB)
PSOSPOS17_2291
PKRAYO71_13055
PFKPFAS1_27480
PSETTHL1_956
PSILPMA3_11010
PYMAK972_2178
PKEDLD99_10585
POJPtoMrB4_10590(rtcB_1)
PGYAWU82_02765
PLALFXN65_04170
PVKEPZ47_14655
PKHJLK41_06230
PATAJWU58_17180
PDWBV82_4969
PZEHU754_019270
PSEPC4K39_2207
PVWHU752_013185
PTRTHU722_0011995
PXAKSS93_06160
PTZHU718_011240
PQIKH389_23920
PANHHU763_002805
PASGKSS96_12480
PFAKKSS94_03025
PMAMKSS90_02895
PALVKSS97_15010
PORYEJA05_03155
PTKEXN22_24440
PTWTUM18999_11520(rtcB_1)
PIEHU724_010865
PGFJ0G10_11765
PCAVD3880_06375
AVNAvin_46150
AVLAvCA_46150
AVDAvCA6_46150
ACXAchr_5350
PBBAKN87_10610
PAGRE2H98_09340
EMODM558_13710
MSQBKP64_05410
PRWPsycPRwf_0858
PURAOC03_04335
PALIA3K91_1758 A3K91_2275
PSYGAK825_04320
PSYCDABAL43B_0978(rtcB3)
PSYAAOT82_801
PSYYDLE54_04320
PSYPE5677_02050 E5677_04605
ACBA1S_2271 A1S_2839
ABYABAYE0642
ABCACICU_03087
ABNAB57_3342
ABBABBFA_00624(rtcB)
ABXABK1_3139
ABZABZJ_03271
ABRABTJ_00618
ABDABTW07_3307
ABHM3Q_3325
ABADABD1_22680 ABD1_27840
ABJBJAB07104_03174
ABABBJAB0715_02669 BJAB0715_03238
ABAJBJAB0868_03133
ABAZP795_2955 P795_5565
ABKLX00_15515
ABAUIX87_11075
ABAAIX88_17380
ABWBL01_10510
ABALABLAC_06440 ABLAC_12310
ACCBDGL_002301
ANORR32_03185
ALCOTEC02_03225
ACALBUM88_13010 BUM88_16355
ASEII8T81_03300 I8T81_06205
ACDAOLE_03025 AOLE_05690
AEIAOY20_01515
ACWA0J50_03020
AHLAHTJS_03285
AJNBVL33_10680 BVL33_14330
ALABFG52_03425
ADVDJ533_09915 DJ533_15425
AWUBEN71_04165 BEN71_07530
AGUAS4_07370 AS4_27000
AUGURS_0465
ADSFPL17_04060 FPL17_18010
ABERBSR55_13415
ACHICDG60_11875
AGYLFPL18_10550 FPL18_17975
MOSAXE82_03005
MBOIDQF64_04205
MCUNNCTC10297_00809(rtcB)
MNNI6G26_04795
MBAHHYN46_03830 HYN46_15655
SALGBS332_02655
PPHEPP2015_3267
PRRAT705_20160
PLZS4054249_23360
CEBB0D95_15110
CELLCBR65_11025 CBR65_17730
CEKD0B88_03650
CEGD0C16_11025 D0C16_23220
SDESde_0273
TTUTERTU_2561
MARQMARGE09_P1719
MICCAUP74_02854(rtcB_1) AUP74_03320(rtcB_2)
MIIBTJ40_00665 BTJ40_08535
MICTFIU95_00535(rtcB1) FIU95_12925(rtcB2)
MHYDGTQ55_10090
MCELLPW13_15290
MICZGL2_12360(rtcB) GL2_29510
CBDCBUD_1265
CBGCbuG_0839
CBCCbuK_1035
ALGAQULUS_15260(rtcB)
ASIPAQUSIP_05400(rtcB)
LPNlpg2201
LPHLPV_2454
LPOLPO_2270
LPULPE509_00897
LPMLP6_2228
LPFlpl2125
LPPlpp2151
LPCLPC_1665
LPAlpa_03159
LPElp12_2193
LLOLLO_0715
LFALFA_2009(rtcB)
LHALHA_2113
LCDclem_04745(rtcB)
LSHCAB17_07900
LLG44548918_00874(rtcB)
LIBE4T55_06475
LCJNCTC11976_01492(rtcB)
LLYJ2N86_06880
TMCLMI_3092
MCAMCA0195
METUGNH96_00790
MMTMetme_0630 Metme_3305
MELLIVG45_03350 IVG45_21630
MAHMEALZ_0270
MBUREQU24_01750
MPSYCEK71_01290
MMAIsS8_0080 sS8_0085 sS8_5553
MOZMoryE10_12480(rtcB)
MISZMishRS11D_09880(rtcB_1) MishRS11D_26480(rtcB_2)
BLEPAL038_00625
THISHZT40_19280 HZT40_21120
TUNJ9260_15040 J9260_16515
TLOJ9253_16795 J9253_17760
TSBHMY34_07855 HMY34_10140
TANIJ8380_03960 J8380_04315
NOCNoc_2009
NHLNhal_1884 Nhal_2955
NWANwat_1815
NWRE3U44_12750
ALVAlvin_3164
TEETel_01470
TSYTHSYN_31845
TTPE6P07_10450
THIPN838_22910
CJAPGWK36_04355
THIMKFB96_10990
TBOGLT988_03155
AEHMlg_1728
HHAHhal_2355
HHKHH1059_02300(rtcB)
TGRTgr7_1950
TNITVNIR_1860(rtcB_[H])
TTITHITH_07195
GAIIMCC3135_09675(rtcB)
TTCFOKN1_2252
HCHHCH_00167 HCH_05061
HAHEENC22_00795 ENC22_07670
HBEBEI_0946
PAURFGL86_16880
AXEP40_01815
MSECLN244_12675
GSNYC6258_00472 YC6258_02055
OMEOLMES_3919
GAPGAPWK_2626
FPPFPB0191_02208
SOKD0B54_20385
SINIGT972_02555
SLIMSCL_0752
SVASVA_2976
EPSL0Y14_05145
NSGH3L94_08250
SALVSALWKB2_1991
CVICV_1037(rtcb)
CHRIDK842_12755
CHRBDK843_18185
CRZD1345_15670
CHAECH06BL_12300(rtcB)
IODEJO50_00650
PSENH8B_1362
RSORSc0224(rtcB)
RSCRCFBP_21263
RSLRPSI07_3186
RSNRSPO_c03176(rtcB)
RSMCMR15_30725(rtcB)
RSEF504_241
RSYRSUY_30540(rtcB_1)
RPJN234_24095
RINACS15_0112
RPUCDC45_01160
RSGJK151_04410
REHH16_B0555(h16_B0555)
CNCCNE_2c05030(rtcB)
CUHBJN34_24370
REUReut_B5869
CTIRALTA_B0354
CBWRR42_s0524
CCUPBKK81_29255
CUPBKK80_27100
CUUBKK79_33020
COXE0W60_07810
BTEBTH_II1314
BTQBTQ_4598
BTJBTJ_5581
BTZBTL_4048
BTVBTHA_3833
BTHEBTN_3619
BTHMBTRA_4318
BTHADR62_3653
BTHLBG87_4055
BOKDM82_5257
BOCBG90_5352
BUUWS70_23025
BSAVWS86_24160
BURBcep18194_B2417
BCNBcen_4671
BCHBcen2424_3692
BCMBcenmc03_3829
BCJBCAM0726
BCENDM39_4438
BCEWDM40_3717
BCEOI35_4625
BAMBamb_5432
BACBamMC406_3587
BCTGEM_5070
BCEDDM42_4362
BCEPAPZ15_20775
BDLAK34_4767
BPYRABD05_18250
BCONNL30_22245
BUBBW23_4393
BDFWI26_17370 WI26_28325
BTEIWS51_27875
BSEMWJ12_23630
BPSLWS57_10340
BMECWJ16_22540
BSTGWT74_22460
BSTLBBJ41_31230
BANNJFN94_21105
BGOBM43_3167
BURKDM992_29140
PHSC2L64_50850
PTSCUJ90_17025
PMEGFNZ07_13685
PACSFAZ98_00020
HYFDTO96_101865(rtcB)
CARIFNU76_11055
BAVBAV3408(rtcB)
ACHRC2U31_17460
ADYHLG70_27345
PHNPAEH1_10675
PACRFXN63_03230
RFRRfer_3852
RSBRS694_03800
POLBpro_1473
PNAPnap_0498
AAAAcav_0015
ACKC380_03580
ACIOEAG14_18315
AANTHUK68_19425
DACDaci_0678
DELDelCs14_5853
DTSBI380_21340
DHKBO996_03455
DLAI6G47_21275
VAPVapar_4421
VPEVarpa_5105
VPDVAPA_1c45930(rtcB)
VBOCKY39_27795
VAMC4F17_23565
CTESO987_17695
CSERCCO03_16770
CODOLAD35_05465
OTOADJ79_06150
OTKC6570_05660
OTDJ1M35_20270
DIHG7047_23135
DAERH9K75_13990
DRGH9K76_20730
STHMIS481_00570
PBHAAW51_0249 AAW51_0609
KIAG8A07_00125
METPC1M51_09240
JAGGJA_256(rtcB)
JABVN23_12385
JAZYQ44_22295
JALBZG29_05870
JASFJQ89_20870 FJQ89_21540
JLVG3257_28180
HHFE2K99_00120
CARELT85_0053(rtcB)
CPRACPter91_0056
MNRACZ75_20160 ACZ75_20555
MASWAM586_00085
MASSCR152_06125
MASZC9I28_05965
MASYDPH57_16055
MALIEYF70_30645 EYF70_30665
MUMFCL38_18735
MFLAGO485_14375
MPLIE1742_19905
MANCIV454_12270
NOKFAY22_17535
SUTKFG381_02480
RDPRD2015_46
MIUABE85_18840
RGUA4W93_00385
BBAYA4V04_11405
NETNeut_0880
NITNAL212_2713
NIINit79A3_2907
NCOAAW31_18070
NURATY38_06835
NSTNstercoris_01601
NMUNmul_A0903
NLCEBAPG3_006780
TBDTbd_2359
FKUFGKAn22_07760(rtcB)
SULFCAP31_10060
SLACSKTS_24620(rtcB)
URUDSM104443_03144(rtcB)
UPLDSM104440_02736(rtcB)
ARESIWH25_07560
NIVJY500_20515
ABREpbN1_39630(rtcB)
APETToN1_40710(rtcB)
DARDaro_1873
AZOazo0079(rtcB)
AOAdqs_0089
AZAAZKH_1503 AZKH_2570(rtcB)
AZRCJ010_08205
TMZTmz1t_1711 Tmz1t_2130
THKCCZ27_12150
AZQG3580_00690
FPHOSHINM1_002920(rtcB)
APPCAP2UW1_1764
DDZDSYM_14180
BEBABWI17_02180
GSUGSU1684
GSKKN400_1706
GMEGmet_1619
GPIGPICK_07990
GAOA2G06_08620
GBZJZM60_13250
GEMGM21_3271
GEBGM18_3507
GEFFO488_14670
GURGura_1393
GEOGeob_2321
GLOGlov_0158
GBMGbem_0989
GBNGEOBRER4_31490(rtcB)
GSBGSUB_15505
GERKP004_15295
GSUBKP001_20960
GNTKP003_15170
GPLM1B72_17430
PCAPcar_0019 Pcar_2835(rtcB)
PACEA6070_00430
PEFA7E78_10200
PPDPpro_2142
DESDSOUD_0074
DEUDBW_3579
DVEDESUT3_39560(rtcB)
DVUDVU_0853
DVLDvul_2130
DVMDvMF_2898
DVGDeval_0783
DSDGD606_01385
DMADMR_25460
DCBC3Y92_11750
DGGDGI_0981(rtcB)
DMSE8L03_14900
DSADesal_2495
DHYDESAM_22337(rtcB)
DAFDesaf_3313
DASDaes_1800
DSXGD604_08795
DBADbac_0699 Dbac_1279
DOAAXF15_04500
DRTDret_0333
DAKDaAHT2_1047
DPRDespr_2496
DEOCAY53_01575
DOGHP555_00265
DBKDGMP_05230
DOLDole_2571
DMLDmul_39100(rtcB)
DALDalk_3935
DATHRM2_05280(rtcB)
DTOTOL2_C37110
DOVDSCO28_54110(rtcB)
DWDDSCW_31440(rtcB)
DALKDSCA_49530(rtcB)
DLIdnl_17350(rtcB)
DMMdnm_045420(rtcB)
DEKDSLASN_04580
ADEAdeh_0946
ACPA2cp1_1004
AFWAnae109_0986
ANKAnaeK_1007
MXAMXAN_0064 MXAN_0280 MXAN_4982 MXAN_5426
MSDMYSTI_00055 MYSTI_00276 MYSTI_05473
MYMA176_001906 A176_006713 A176_006953
MFBMFUL124B02_00380 MFUL124B02_01640 MFUL124B02_29855
CCXCOCOR_00071 COCOR_02473 COCOR_07765
MFULILAB_07260 LILAB_08425 LILAB_32835
MMASMYMAC_000073 MYMAC_000307 MYMAC_004864
SURSTAUR_0111 STAUR_5804
AGEAA314_00616 AA314_03647 AA314_03871
AVMJQX13_13405 JQX13_33440 JQX13_42440 JQX13_50190
MBDMEBOL_003461 MEBOL_005825 MEBOL_007133
CFUSCYFUS_000098 CYFUS_003559 CYFUS_006797
VINAKJ08_3451
SCLsce1307 sce3688 sce7156(rtcB)
SCUSCE1572_08850 SCE1572_22220 SCE1572_41680
CCROCMC5_067850 CMC5_067940
PAUUE8A73_014865 E8A73_038995 E8A73_041515
SAMYDB32_000590 DB32_000753 DB32_004980 DB32_008295
LLUAKJ09_00467 AKJ09_01229 AKJ09_08185
MRMA7982_11935 A7982_13457
HOHHoch_0235
SATSYN_02046
DAODesac_0741
DTIDesti_4203
SFUSfum_2726
DAXFDQ92_01175
HMRHipma_0780
PCAYFRD00_10030 FRD00_20390
BBAEFRD01_18415
DHRLGS26_06730
BRABRADO2887
BBTBBta_5290
AOLS58_47240
BRCBCCGELA001_16670
BROBRAD285_2625
BRKCWS35_21840
BDGLPJ38_22110
BSEPHAP48_0035540
BQBJ4P68_0036790
MNOMnod_4254
MHEYH2LOC_000620 H2LOC_001180
MTWCQW49_22300
TSOIZ6_25590(rtcB)
CMBCSW64_14990
BSBBresu_1614
BRDJL11_08050
BRFE4M01_11845
BMEDGYM46_02500
BNDKWG56_08945
BPONIFE19_11425
BVITJIP62_14515
AEXAstex_2072
TSVDSM104635_01120(rtcB)
TMDKUV46_00085
CBOTATE48_04675
HBCAEM38_01295
NOTC7W88_17265
SMAGAN936_20225
SPHQBWQ93_08190
SSANNX02_17430
SPLMBXU08_13595
SPHCCVN68_13265
SECHB18_13105
SRHIH9L12_00865
SPAPH3Z74_19645
SSUAFPZ54_01725 FPZ54_12540
SSYSLG_10960
SYBTZ53_04225
SPHJBSL82_09730
SMICSmB9_19760(rtcB)
SPHSETR14_18905
SANDH3309_04980
ANHA6F65_00507(rtcB)
ERRDVR09_02375
ERFFIU90_13350(rtcB)
PNSA9D12_07470
NAOY958_07855
MAGXXM1_0077
TMOTMO_c0758
HTQFRZ44_15010(rtcB)
HADHFRZ61_14690(rtcB)
DEXHWD60_10335
MAGQMGMAQ_3163
KOZKFF44_13495
BBABd2854
BBATBdt_2795
BBACEP01_10385
BDCDOE51_14530
BANBA_2999
BARGBAA_2999
BATBAS2787
BAHBAMEG_1606
BAIBAA_3052
BAXH9401_2861
BANTA16_30250
BANRA16R_30720
BANSBAPAT_2876
BANHHYU01_14825
BANVDJ46_1760
BCABCE_3035
BCZBCE33L2717
BCRBCAH187_A3033
BCBBCB4264_A3237
BCUBCAH820_2997
BCQBCQ_2815
BCXBCA_3069
BALBACI_c29530
BNCBCN_2839
BCFbcf_14640
BCERBCK_19915
BTKBT9727_2736
BTLBALH_2684
BTTHD73_2776
BTHRYBT1520_13630
BTHIBTK_13765
BTCCT43_CH3175
BTFYBT020_14910
BTGBTB_502p06960(rtcB) BTB_c33090(rtcB)
BTHTH175_ch3230
BTHUYBT1518_17660
BTWBF38_4152
BTHYAQ980_17210
BWEBcerKBAB4_2963
BWWbwei_1817(rtcB)
BMYOBG05_2841
BBYCY96_14950
BWDCT694_16005
BTROFJR70_04175
BMOBMLA2C4_15775
BFDNCTC4823_03322(rtcB)
BBADK7T73_10500
BACOOXB_2231
BACAFAY30_05655
BCIRC2I06_07325
BEOBEH_14030
BHABH1789
BCLABC1919
BLEBleG1_3454
CGOTJ1899_10900
LSPBsph_3380
LFUHR49_09610
LYSLBYS11_13545
LYBC3943_14710
LPAKGDS87_14115
LMACI6G82_06195
PSYHD0S48_12885
PSYOPB01_20095
NMKCHR53_05805
BOUI5818_02830
GAJMY490_10865 MY490_17535
SLMSMM221_04710
HYIK2M58_07620
MACRBHM04_03260
MBOEHT586_07450
LMOlmo0257
LMNLM5578_0295
LMYLM5923_0294
LMTLMRG_02652
LMOCLMOSLCC5850_0248
LMODLMON_0254
LMOWAX10_09800
LMOQLM6179_0555
LMRLMR479A_0268
LMOMIJ09_09015
LMFLMOf2365_0265
LMCLm4b_00273
LMOGBN389_02680
LMPMUO_01420
LMOLLMOL312_0250
LMOJLM220_01502
LMOZLM1816_08955
LMOXAX24_13975
LMHLMHCC_2382
LMQLMM7_0281
LMLlmo4a_0274
LMGLMKG_01667
LMSLMLG_0804
LMJLMOG_02579
LMWLMOSLCC2755_0250
LMXLMOSLCC2372_0258
LMZLMOSLCC2482_0252
LMONLMOSLCC2376_0226
LMOSLMOSLCC7179_0248
LMOOLMOSLCC2378_0265
LMOYLMOSLCC2479_0257
LMOTLMOSLCC2540_0258
LMOALMOATCC19117_0260
LMOKCQ02_01410
LMVY193_14555
LWElwe0220
LSGlse_0242
LIVLIV_0230
LIIJL52_01495
LIWAX25_01495
LIAJL58_01390
LIOJL53_01730
LWIUE46_01235
LMARLAX80_001235
BTHSCNY62_12025
ESIExig_1120
EATEAT1b_2401
EANEab7_1089
EXMU719_05830
EAPKB235_13440
EACEKKI46_06015
BLRBRLA_c020570
BRWGOP56_03160
PJDPjdr2_4667
PPYPPE_00892
PPMPPSC2_04630(hint)
PPOPPM_0868(hint)
PPOLX809_04275
PPQPPSQR21_009240(rtcB)
PPOYRE92_07335
PSABPSAB_03550
PBDPBOR_03780
PAENP40081_04110
PSTEPSTEL_04515
PPEOABE82_04430
PBVAR543_07355
PXLBS614_12310
PIBBBD41_09210
PKBB4V02_20625
PAIHASL14_07105
PLENEIM92_22755
PALBEJC50_08310
PBACHUB98_24875
PTRIKDC22_03655
PCELHUB94_06535
SACAFFV09_15685
SIVSSIL_3674
SSILSOLI23_00010
SOBCSE16_01285
PANABBH88_10590
PGQFK545_19560
JEOJMA_38210
SPAEE2C16_02435
SPOOJ3U78_03755
VIJJNUCC6_16005
ESSATZ33_16720
EGVEGCR1_06405
ERAFJ9537_08660
CMLBN424_737(rtcB)
JEHEJN90_07655
CACCA_C3382
CAESMB_G3419
CAYCEA_G3385
CBECbei_3556
CBZCbs_3556
CBEILF65_04004
CCBClocel_3404
CSRCspa_c41190
CPATCLPA_c04020(rtcB)
CPAECPAST_c04020(rtcB)
CLTCM240_3073
CFMBJL90_14815
CDYF3K33_18055
CRWCROST_012300
CFBCLFE_036160
CAUNCLAUR_016670
AOEClos_1938
GFEGferi_22905
HHWNCTC503_01772(rtcB)
CALEFDN13_11870
CTHCthe_0250
CTXClo1313_1979
CCLClocl_0797
HSCHVS_05280(rtcB)
RHEREHE19_004265
CSSCst_c22780(rtcB)
CSDClst_2183
EHAEthha_1255
RALRumal_1015 Rumal_2169
RUSRBI_I00657
RUJE5Z56_07445
OVAOBV_31920
ACOLK5I23_02580 K5I23_13310
BPBbpr_III119
CLEClole_4183
CEWEKH84_02415
RIMROI_33100
LACYA4V08_17640
CSOCLS_28730
HSDSD1D_0548
LUAD4A81_02325 D4A81_05150
ACELacsn021_20310 acsn021_30600
ACHTbsdcttw_01360
RTORTO_04160
CBOLCGC65_30485
SSUNH9Q77_03000
ERAERE_33150
LBWC3V36_01905
EACEAL2_c15240
TEMJW646_00135
TGCL0P85_08220
TEBT8CH_1447
STHSTH1327
SLPSlip_2150
SALQSYNTR_1006
DSYDSY1431
DHDDhaf_2546
DDHDesde_2033
DMIDesmer_2431
PTHPTH_1582(RtcB)
DFGB0537_00870
DAEDtox_3800
DKUDesku_1497
DAUDaud_0477
TFRBR63_15775
FWADCMF_12090
VGUHYG85_07480
VPYHZI73_24985
TMRTmar_2086
THEFE1B22_01985
LASAL9O85_09605
AMICAmi3637_12395
BPRMCL3_11340
TTETTE0709(RtcB)
TPDTeth39_1588
TITThit_0712
TMTTmath_0763
TBOThebr_1627
TWIThewi_0832
TKITKV_c06970(rtcB)
ADGAdeg_1757
TPZTph_c23770
TTOThethe_02918
TSHTsac_2743
TOCToce_1735
NCDACONDI_02984(rtcB)
AFTBBF96_05205
KMEH0A61_02734(rtcB)
MHAPJFY71_04905
KPARJL105_11225
SSGSelsp_2126
SELEADJ74_00055
AINAcin_1304
LPILLIP_0340
MTURv2631
MTVRVBD_2631
MTCMT2707
MRAMRA_2659
MTFTBFG_12650
MTBTBMG_01340
MTKTBSG_01350
MTZTBXG_001329
MTGMRGA327_16190
MTIMRGA423_16440
MTECCDC5079_2428
MTURCFBS_2784
MTLCCDC5180_2398
MTOMTCTRI2_2681
MTDUDA_2631
MTNERDMAN_2891
MTJJ112_14115
MTUBMT7199_2665
MTUCJ113_18345
MTUEJ114_14075
MTXM943_13605
MTUHI917_18570
MTULTBHG_02569
MTUTHKBT1_2775
MTUUHKBT2_2778
MTQHKBS1_2782
MBOBQ2027_MB2664
MBBBCG_2658
MBTJTY_2652
MBMBCGMEX_2650
MBKK60_027370
MBXBCGT_2477
MAFMAF_26500
MMICRN08_2913
MCEMCAN_26771
MCQBN44_60098
MCVBN43_40311
MCXBN42_40618
MCZBN45_51025
MMANMMAN_26850(rtcB)
MKNMKAN_19020 MKAN_21805
MYVG155_25065
MHADB586_06115
MDXBTO20_29285
MXEMYXE_14460(rtcB)
MNVMNVI_05760(rtcB)
MPAGC0J29_07695
MHEKJMUB5695_01375(rtcB)
MLJMLAC_10950(rtcB)
MBRDMBRA_47240(rtcB) MBRA_50920
MSHJMSHI_28580(rtcB)
MSENK3U95_05395
MOTLTS72_21270
MFTXA26_50760(rtcB)
MPHLMPHLCCUG_01543(rtcB)
MTHN4412656_01156(rtcB)
MHASMHAS_00467(rtcB)
MBOKMBOE_01100
MABBMASS_3426
CGLCgl3001(Cgl3001)
CGBcg3329
CGUWA5_2899
CGTcgR_2890
CGSC624_14740
CGGC629_14750
CGMcgp_3329
CGJAR0_14540
CGQCGLAR1_14395
CGXSB89_14395
CEFCE2835
CDIDIP2025
CDHCDB402_1881
CDECDHC02_1912
CDRCDHC03_1897
CDACDHC04_1896 CDHC04_1937
CDBCDBH8_0457
CDSCDC7B_0460
CDWCDPW8_0504
CDVCDVA01_1855
CDIPERS451417_00438(rtcB)
CARcauri_0278
CCGCCASEI_05950
CVTB843_03730
CGYCGLY_12595(rtcB)
CHMB842_04730
CSXCSING_01605
CMVCMUST_06615 CMUST_09065
CTEDCTEST_01870
CUTCUTER_09050
CDXCDES_13590
CSPWM42_1082
CSTACSTAT_05255
CCJZccrud_13560
CSTRCBE89_12315
CAQUCAQU_11930
CSPHCSPHI_08820
CAMGCAMM_05485
CXEFOB82_10505
CSANE3227_09990
CRLNCTC7448_01208(rtcB)
CSURN24_3093(rtcB)
CCYSSAMEA4530656_1805(rtcB_1) SAMEA4530656_1824(rtcB_2)
CMATHBA49_01335 HBA49_12245
CPRPI6I69_07455
COKCOCCU_04585(rtcB)
CPOYGP475_03845
BFVC628_15140
NFANFA_13690
NFRERS450000_02738(rtcB)
NCYNOCYR_1438
NBRO3I_009225
NNONONO_c59050 NONO_c60420
NSLBOX37_06775
NSRNS506_06845(rtcB)
NOZDMB37_30005
NODFOH10_22805
NAHF5544_11775
NADNCTC11293_02355(rtcB)
NIEKV110_09765
NTCKHQ06_35400
NHUH0264_34580
NYALTV02_38430
NGPLTT66_04345
RHARHA1_ro06876
REYO5Y_11565
REBXU06_11765
RQIC1M55_12830
ROPROP_68550
ROAPd630_LPD03502
REQREQ_13440
RAVAAT18_23235
RFAA3L23_00586(rtcB)
RHSA3Q41_02769(rtcB)
RRZCS378_13010
RHODAOT96_23030
RKOJWS14_37055
RGOKYT97_00250
ROZCBI38_16940
GORKTR9_3108
GTABCM27_15960
GRUGCWB2_17505(rtcB)
GOMD7316_02205(rtcB)
GAMGII34_05800
GPDGII33_05115
GJIH1R19_15075
GHNMVF96_15455
GAMIIHQ52_20255
TPRTpau_0543
TSMASU32_02855
TPULTPB0596_05640
DLUA6035_07590
SCOSCO3299(SCE15.16c)
SALBXNR_3545
SMASAVERM_4753
SGRSGR_4185
SGBWQO_14680
SCBSCAB_38881
SSXSACTE_2751
SVLStrvi_0717
SHYSHJG_5623
SHOSHJGH_5384
SRCM271_22380
SMALSMALA_4317
SSOII1A49_25670
SCTSCAT_3437(rtcB) SCAT_5020
SCYSCATT_34230 SCATT_50120
SFASfla_3574
SBHSBI_06030
SVESVEN_3171
SDVBN159_3960(rtcB)
SALSSLNWT_2798
STRPF750_3148(rtcB)
SFISFUL_2975
SCIB446_21115
SALUDC74_3951
SALLSAZ_20890
SLVSLIV_21295(rtcB)
SGUSGLAU_02850(rtcB1) SGLAU_19240(rtcB2)
SVTSVTN_16505
STREGZL_04947
SCWTU94_18750 TU94_30525
SLDT261_4518
SLCSL103_01555
SXISXIM_50600
STRMM444_20030
SAMBSAM23877_4256(rtcB)
SPRISPRI_3335
SCZABE83_21100
SCXAS200_21280
SRWTUE45_05006(rtcB)
STRFASR50_20445
SLEsle_06760(sle_06760) sle_31340(sle_31340)
SRNA4G23_02879(rtcB_1) A4G23_03205(rtcB_2)
SPAVSpa2297_18660
STRTA8713_17845
SCLFBB341_11040
SGSAVL59_03270
STSIA4E84_23175
SKYD0C37_19345
SALWCP975_20130
SGMGCM10017557_47380
SCADDN051_17725
SLSSLINC_4848
SNRSNOUR_02490 SNOUR_22650
SPLULK06_013290
STRDNI25_16645
SNWBBN63_13745
SAUOBV401_25430
SSIAA7J05_15860
SVUB1H20_13980
SPUNBFF78_18645 BFF78_38200
SGVB1H19_19585
SLAUSLA_0816 SLA_3231
SALFSMD44_04968
SALJSMD11_3719
SLXSLAV_21630(rtcB)
STROSTRMOE7_18305
SFKKY5_4574
SNZDC008_19850
SGEDWG14_03680(rtcB)
SRJSRO_3229
SLKSLUN_22890
SDXC4B68_12825 C4B68_17300
SGDELQ87_16830
SQZFQU76_19955
SCYAEJ357_04175 EJ357_26595
SASTCD934_17440
SNQCP978_19335 CP978_21800
STIRDDW44_17220
SKACP970_18555
SGZC0216_02240
SVNCP980_14725
SNKCP967_19630
SHAWCEB94_23440
SRKFGW37_14825
SFICEIZ62_00545 EIZ62_13800
SGALCP966_20920
SSPODDQ41_18285
SVRCP971_10355 CP971_31555
SPADDVK44_12880
SFYGFH48_18260
SAQUEJC51_27865
SGFHEP81_03438
SCAVCVT27_13500
SSEOD0Z67_16560
SBYH7H31_14015
SRIMCP984_21520
SSUBCP968_14770
SPHVF9278_29575
SCINCP977_15250
SFUGCNQ36_19970
SPACB1H29_16110
STSUB7R87_19465
SCHACP983_18515
SGXH4W23_17860
SCOECP976_24880
SBATG4Z16_13090
SSPBCP982_24145
SNFJYK04_04940(rtcB)
SPLACP981_18080
SBROGQF42_25215 GQF42_41260
STUIGCM10017668_39990
SATAC5746_18395 C5746_41280
SCHFIPT68_01360 IPT68_20730
SHUNDWB77_03390(rtcB)
SHARHUT13_25560
SCYGS1361_22535(rtcB)
SFEUIM697_19695 IM697_41690
SLIAHA039_14250
SDWK7C20_17255
SVDCP969_22280
SCALI6J39_14205
SAUHSU9_015435
SFBCP974_15580 CP974_17385
SMOBJ7W19_14650
SPRACP972_20530
SPEUCGZ69_20330
SROIIAG44_16925
SXNIAG42_15100
SGJIAG43_18020
SHKJ2N69_21170
SANUK7396_19530
SDDD9753_15165
SACTDMT42_22265
SMAOCAG99_19670
SGOBtest1122_05995 test1122_15195
SINEKI385_21250
SLFJEQ17_26500
SDECL3078_27080
KSKKSE_54190
KABB7C62_14045
KAUB6264_05435 B6264_29425
KITCFP65_5277
STRIC7M71_002865 C7M71_022780
YIALO772_15015
LXLKDY119_01653(rtcB)
MTSMTES_0446
MIPAXH82_09900
MPALBO218_01385
MIHBJP65_04150
MOYCVS54_00843(rtcB)
MSFIT882_11530
MICSC1N74_09820
MBINLXM64_00540
RTXTI83_03640
RTCAPU90_02830
RIAC7V51_00310
RFSC1I64_11050
RTEGSU10_04445
CUMNI26_01615
CUBBJK06_06395
CUGC1N91_01405
CQFGBG65_08750
AGMDCE93_12595
AMAUDSM26151_25260(rtcB_2)
ASOIMTP13_08035
CPHYB5808_14405
HUMDVJ78_06325
LVIG7068_11910
HEAHL652_02305
FRNF1C15_12535
SUBTKPL76_07285
ARTArth_3119
ARUASPU41_01585
ARQBWQ92_15855
ACRYAC20117_05155
ARTHC3B78_14850
ACITHPK19_05350 HPK19_12745
ARIUM93_10445
ACHAchl_4478
APNAsphe3_29420
PSULAU252_16040
PSNINIBR502771_10200
GARAOZ07_00845
RSARSal33209_0887(rtcB)
CIGE7744_03670
PAEYKUF55_13180
BFABfae_05440
JDEJden_1934
DAYFV141_00625
YIMJ5M86_09485
CETB8281_11810
CCEUCBR64_19765
SANWG7063_07530
CFLCfla_0012
CFICelf_0498
CGACelgi_1311
CELZE5225_03005
CEJGC089_03385
CELHGXP71_18980
OEKFFI11_012595
ICAIntca_2066
PHWG7075_12345
SERJSGUI_2324
ORNDV701_04555
ORZFNH13_08650
BLINBLSMQ_2835
BCAUI6G59_16125
DEMLGT36_012850
PFRPFREUD_23600
PFRERM25_2257
PPCHMPREF9154_1687(rtcB)
ARUBJ5A65_07060
PBOPACID_01500
AACIASQ49_04330
ACIJJS278_00105(rtcB)
MPHMLP_03420
TFABW733_16405
TESBW730_06055
PRVG7070_04105
BRTJ4N02_15715
NBEBack2_27760
NAQUENKNEFLB_00993(rtcB)
NROK8W59_04965
PSIMKR76_06090
AERAERYTH_06375
MGGMPLG2_1348(rtcB)
KFLKfla_6625
KQIF1D05_17840
TFUTfu_1357
THAONI17_004485
TALXFOF52_03945
NDANdas_1411
NALB005_4010
NGVCDO52_13375
NEXNE857_12930
SAIUJ4H86_04160
TCUTcur_2027 Tcur_2265
ACTWF7P10_00920 F7P10_01935
AGRAAGRA3207_000560
SROSros_5339 Sros_5947
NOABKM31_51670
NCXNocox_36705(rtcB1)
NGNLCN96_49690
TBITbis_0835
FREFranean1_3926
FRIFraEuI1c_4903
FALFRAAL4283
NMLNamu_1716
NAKEH165_03215
GOBGobs_3677
BSDBLASA_3986
MMARMODMU_4048
KRAKrad_1410
SENSACE_3596
SACGFDZ84_30650 FDZ84_32760
SVISvir_23210
SACCEYD13_12925(rtcB)
AMDAMED_8879
AMNRAM_45555
AMMAMES_8744
AMZB737_8745
AOIAORI_7651
AJAAJAP_39890(rtcB)
AMQAMETH_5233
AMYCCU254_36955
AMYBBKN51_31545
AABA4R43_27325
AMYYYIM_02070(rtcB)
AORISD37_02335
PSEEFRP1_15925
PSEQAD006_23575
PECQAD017_03165
APRECNX65_07325
AMIAmir_1475
SESPBN6_17540(rtcB)
KALKALB_6876
KPHYAOZ06_00830
LEDBBK82_01585
AHMTL08_23515
ACTIUA75_27355
ACADUA74_26765
AHGAHOG_24665(rtcB)
ALOCRK60868
PMADBAY61_14880
STPStrop_0639 Strop_2399
SAQSare_2548
MAUMicau_3386
MILML5_5008
MICBMicB006_2446
MTUACSH63_08120
MICHFJK98_16880
MTEMGCE86_11705 GCE86_12865
MCABHXZ27_18700
MSAGGCM10017556_54610 GCM10017556_55830(rtcB)
VMAVAB18032_19995 VAB18032_21020
ASEACPL_2722(rtcB)
ACTSACWT_2824
AIHAiant_76580
PLKCIK06_17310
VERHUT12_17595
ATLAthai_40070
PRYPrubr_19620
CATICS0771_43700
NHYJQS43_25215
CAICaci_2449
SNASnas_4449
NAVJQS30_11400
GLYK3N28_02955
AEYCDG81_00415
RXYRxyl_0480
AQZKSP35_07340
ELEElen_2615
OLOADJ70_06260
SYPSYNPCC7002_A2515
CYACYA_2537
SYNPSyn7502_03203
SYVAWQ23_12535
SYLAWQ21_11910
AMRAM1_4754
LEPLepto7376_2563
LENLEP3755_37030
LBOLBWT_28130
LSKJ5X98_14690
PSERABRG53_1080(rtcB)
GLPGlo7428_3414
GENGM3709_1172
GEEGM3708_2888
MARMAE_13610
MPKVL20_1823
MIQB5D77_09480
MVZmyaer102_47640
CANCyan10605_1114
CYLAA637_02110(rtcB)
HAOPCC7418_0262
CYCPCC7424_2770 PCC7424_4795
CYJCyan7822_1196 Cyan7822_3936
CYNCyan7425_0530
PPSUNO713_02867(rtcB)
OXYHCG48_23490
MVAGD0A34_10725
MICMic7113_1604
GEIGEI7407_3135
OACOscil6304_2475
ONIOsc7112_4412
CEPCri9333_4428
ANAall3526
NOSNos7107_2055
NOPNos7524_1341
NONNOS3756_43600
NFLCOO91_02837
NSHGXM_03770
NEDHUN01_20250
AVAAva_3418
ACYAnacy_0605
ANNEH233_11335
CSGCylst_4779
RSINB6N60_03858
CALTCal6303_3287
CALHIJ00_12925
FISFIS3754_26020 FIS3754_31200
NSPBMF81_01032(rtcB)
NSPHBDGGKGIB_03275(rtcB)
TOQHCG51_15215
NCNBZZ01_30255
CTHEChro_3580
PLPPle7327_0388
STANSTA3757_14750
DETDET0823
DEHcbdbA801
DEBDehaBAV1_0742
DEVDhcVS_727
DEGDehalGT_0703
DMCbtf_744
DMDdcmb_790
DMGGY50_0737
DMXX792_03830
DMYX793_03995
DMZX794_03630
DUCUCH007_06890
RRSRoseRS_4508
RCARcas_0873
CAUCaur_0538
CHLChy400_0576
CAGCagg_1306
HAUHaur_0205 Haur_0812
TROtrd_A0625
STISthe_3251
ATMANT_11350
ABATCFX1CAM_1516(rtcB)
PSUBPelsub_P1427
LEKhrd7_34200
CAPCLDAP_38680
PBFCFX0092_A2977(rtcB)
THUGKNN16_12750
TTRTter_0374
PMETG4Y79_14400
DRADR_0430
DDRDeide_21600 Deide_3p01893
DMRDeima_2898
DPTDeipr_0150
DGODGo_CA2745
DPDDeipe_0903
DSWQR90_01110
DCHSY84_07550
DABAUC44_14525
DPUSU48_00270
DEZDKM44_01110
DWUDVJ83_13310
DFCDFI_13075
DEINDAAJ005_16040
DGADEGR_29040(rtcB)
DPHEHF33_09425
DRDLMT64_10440
TTHTT_C1426(rtcB)
TTJTTHA1785(TTHA1785)
TTSThthe16_1802
TTLTtJL18_0257
TSCTSC_c00070
THCTCCBUS3UF1_2960
TOSTheos_1904
TAQTO73_2168
TBCA0O31_01006
TANTKNN15_04155
MSVMesil_3081
OPROcepr_0289
MHDMarky_0194
CCZCCALI_02856
FGIOP10G_3895
NPYNPRO_16140
PUVPUV_02890(rtcB)
NEYNCS13_1_1652
SNGSNE_A12060(rtcB)
AMUAmuc_0909
ROOG5S37_25595
LUOHHL09_04075
LAMBKBB96_16880
MINMinf_0304(rtcB)
MKCkam1_1856
MEAPMTHMO_0265(rtcB)
RBARB9360(rtcB)
PSLPsta_0360
PIRVN12_02940(rtcB)
RULUC8_32090(rtcB)
RMLFF011L_08330(rtcB)
MFFMFFC18_05570(rtcB_1) MFFC18_30210(rtcB_2)
ROLCA51_31460(rtcB)
AHELQ31a_10340(rtcB)
LCREPla8534_65130(rtcB)
AAGGETAA8_33370(rtcB)
BVOPan97_36220(rtcB)
RLCK227x_52220(rtcB)
TTFTHTE_4461
LPAVPLANPX_3399 PLANPX_3966 PLANPX_5890
AMUCPan181_24420(rtcB_1) Pan181_28080(rtcB_2)
PNDPla175_19100(rtcB_1) Pla175_37470(rtcB_2)
AMOBHG15A2_25060(rtcB_1) HG15A2_25600(rtcB_2)
PLMPlim_3385
PEHSpb1_41020(rtcB)
PBSPlabr_0027
PLSVT03_20620(rtcB_1) VT03_28500(rtcB_2)
PLHVT85_08960(rtcB)
FMRFuma_00756(rtcB)
GMRGmarT_13400(rtcB)
GIMF1728_08030
GPNPan110_13280(rtcB)
MRIMal4_35750(rtcB)
SDYNMal52_08900(rtcB_1) Mal52_49330(rtcB_2)
PLONPla110_36940(rtcB)
GESVT84_20705(rtcB_1)
GOGC1280_10890
GMSSOIL9_17510
TIMGMBLW1_40190
LRSPX52LOC_06096
FTJFTUN_8104
ULIETAA1_24700(rtcB)
IPAIsop_1031
SACISinac_5138
PBORBSF38_04344(rtcB)
AGVOJF2_50610(rtcB_1) OJF2_57740(rtcB_2)
KSTKSMBR1_1908
BROCIPI25_12090
BPITBPIT_34180
JETL3J17_03055 L3J17_12680
PBASSMSP2_00402(rtcB)
ALUSSTSP2_01744(rtcB)
HBSIPV69_14850 IPV69_22555
UAMUABAM_05778
VAIBU251_06780
TDETDE_0804
TPEDTPE_0764
TPKJO40_08015
TPHGFUT81_14500
TRIDYE50_05195 DYE50_05295
STASTHERM_c16050
STQSpith_1665
TAZTREAZ_3571
SCDSpica_2226
BHCJFL75_04210 JFL75_04890
BHYBHWA1_02202
BHDBHYOB78_05145
BRMBmur_2099
BIPBint_2476
BHPBHAMNSH16_05090
ABAAcid345_1273
GMAAciX8_4596
TALBFTW19_06860
PFERIRI77_13530 IRI77_18525
ABACLuPra_00138(rtcB)
THYDTTHT_0282
SCORJ3U87_14930
EPOEpro_1088
FVAFV113G1_25930(rtcB)
FULC4N20_10705
FMOC4N19_10560
LEOAMK43_06325
STRSterm_1373
ACOAmico_1547
TLITlie_1383
AMOAnamo_1406
GBAJ421_5518
BTHBT_1455
BTHOBtheta7330_01760(rtcB)
BFRBF2711
BFSBF9343_2642
BFGBF638R_2737
BFBVU15_12170
BXYBXY_02790 BXY_44620
BOABovatus_00921(rtcB_1) Bovatus_01503(rtcB_2)
BCELBcellWH2_01238(rtcB_1) BcellWH2_04175(rtcB_2)
BCAEA4V03_11335
BISDXK01_010325
BSTEK6V31_07540
BNOK8P02_07830
BSABacsa_1261
DYSG7050_00075
PARYA4V02_03400 A4V02_03410
COPRCop2CBH44_10930
BVIRI6J59_10335
ALQC7Y71_002345
TTZFHG85_09065
MCOSGM418_00540
ASXCDL62_16255
RMRRmar_0504
RMGRhom172_0502
CPICpin_2291 Cpin_7273
CBAECOR50_03110
CHITFW415_02390
CHIHGWR21_15705 GWR21_26710
COYHF329_10520 HF329_18330 HF329_23665
CFILMYF79_27840 MYF79_32215
NKONiako_6740
NSONIASO_15555
NIAA8C56_20930
FLASY85_20040
FGGFSB75_18630
ARBA9P82_10180
AGIFSB73_03250
ARACE0W69_004425
FLNFLA_5385 FLA_6082
PSEGD3H65_25260
PGINFRZ67_06110
PGOFSB84_04875
FLSGLV81_03365
LACSH4075_01850
FLPLK994_03435
HHYHalhy_6076
SGNSGRA_3976
PHEPhep_0086
PEPAQ505_13395
PSTYBFS30_05935 BFS30_05955
PEKFFJ24_018920
PROEH9L23_19690
PEXIZT61_10875
SHGSph21_5037
SHTKO02_01970
SPHNBV902_15295 BV902_18300
SMIZ4412673_01206(rtcB_1) 4412673_01351(rtcB_2)
SPHZE3D81_05995
SPHEGFH32_06175 GFH32_16525
SPDRG6053_10955 G6053_13065
SDJNCTC13534_02108(rtcB_1) NCTC13534_02131(rtcB_2)
STHANCTC11429_04181(rtcB)
SSPII6J01_10310 I6J01_13585
SMUII6J00_03930 I6J00_06715
SSIYJVX97_13270 JVX97_17355
SCNSolca_0243 Solca_3875
MUPA0256_14655
MUCMuYL_3576
MGOTMgSA37_00547(rtcB_1)
MUHHYN43_021725
MGKFSB76_11980 FSB76_17660
MRUBDEO27_014405 DEO27_023750
MGOSDIU38_014605 DIU38_028175
MMABHQ865_20135 HQ865_20925
MDJLLH06_19235
OLIFKG96_22780
SBXCA265_18465
CHUCHU_2904
SLISlin_1492
SRDSD10_13890
SPIKEXU85_21585
SPIBG8759_17410
RHOZGXP67_14500
DFEDfer_3725
DSNHWI92_17095
RSIRunsl_3734
RUPDTQ70_03195
FAEFAES_3385
FIBA6C57_13655
HSWHsw_1616
HYMN008_15670
HYDPK28_11720
HYEAM218_04715
HYGAUC43_18940
HYPA0257_00090
HYZAXW84_13285
HNVDDQ68_07860
HYHD3Y59_02840
HYJFHG12_15875 FHG12_15885
HQIH9L05_14510 H9L05_14515
HRSHER32_02860 HER32_02870
HBNGUY19_01470 GUY19_01475
HTSHMJ29_19780
HMTMTP16_12890 MTP16_12900
HTBMTX78_03440 MTX78_13660
PKOPKOR_20620
RUFTH63_14105
RTIDC20_04675
RUDTH61_03095
NIBGU926_08740
ADDHUW48_14815 HUW48_25930
ASWUHUW51_22835 HUW51_23080
FYAKMW28_17475
FBTD770_13270
CHECAHE_0550(rtcB)
CHKD4L85_07640 D4L85_07660
FPSZAMR72_14825
FJOFjoh_3458 Fjoh_4745
FJGBB050_02854(rtcB_1) BB050_04279(rtcB_2)
FBRFBFL15_1051(rtcB)
FCOFCOL_03070 FCOL_07605
FINKQS_11450(rtcB)
FATDVK85_06425
FKIFK004_09785 FK004_17380
FALBHYN59_00405 HYN59_04120
FCRHYN56_14765
FSEDI487_09885 DI487_11035
FAKFUA48_18020
FFLHYN86_12730 HYN86_19500
FENJ0383_01485
FCVAWN65_01800 AWN65_02540
FOEJJC03_11890
FSDLXD69_17745
CHGAXF12_03720
CAPNCBG49_02610
CGHCGC50_08795
CLKCGC53_05250
CSPUCGC55_07145
CCYNCGC48_02325
CSTOCGC58_10805
CAPFFOC45_11110
MLTVC82_600
AEVEI546_13355
PPECH9W90_06235
PCEAJ3359_16990
MYRMYRA21_0517 MYRA21_1968
MPWMPR_0760 MPR_3048
MODAS202_02000 AS202_09360
MYZBK054_02125 BK054_09225
MOAI6I89_02060 I6I89_13490
WINWPG_1501
SYISB49_03050
TENLPB136_04430
TJETJEJU_2154
TMPF9Y86_00210
LULLPB138_07195
AALGAREALGSMS7_03981(rtcB)
OLLCW732_02525
KOSKORDIASMS9_00982(rtcB)
KANIMCC3317_30260(rtcB_2)
AQBD1818_18460
AQAD1815_12970
AQDD1816_14010
PSYNE9099_07530
AFLAFHG64_05055
ANPFK178_09000
OCIFEZ18_11230
MESQC7H62_1147
FLGLV716_05030
SABUMBM09_09680
FBMMQE35_17380
EAOBD94_3903
EMNM876_16360
EENBBD30_07450
ELBVO54_02794(rtcB_2)
EMGBBD33_04230
EGOBBD34_08565
EGMAYC65_18385
ELZFCS00_11465
CHZCHSO_4773(rtcB)
CGNOK18_06740
CIHATE47_18075
CHHA0O34_10305
CIOCEQ15_17165
CHRYCEY12_13415
CHRSEAG08_12435
CARHEGY05_20650
CSHAEG350_01000
CNKEG343_12965
CJTEG359_13660
CILEG358_00665
CCAUEG346_07650
CBENEG339_04590
CGLENCTC11432_03082(rtcB_1)
CTAINCTC12078_02564(rtcB_1)
CLACEG342_04140
CBPEB354_20895
CNPM0D58_10280
CCAOH5J24_23890
CFAELL667_07355
EZEKI430_13315
EBVF0358_06880 F0358_16900
EFALFH779_04390 FH779_14775
CRMK6119_09365
CTECT0601
CPCCpar_0618
CLZBIU88_08010
PROSCHL67_03195
CTSCtha_1975
IALIALB_1250
MROMROS_0532
CPRVCYPRO_3003
AAEaq_032
HTHHTH_1018
HTEHydth_1015
TALThal_0159
TRDTHERU_07650
PMXPERMA_0847
TTKTST_1313(rtcB)
TAMTheam_1026
DTEDester_1138
TMATM1357
TMMTmari_1364
TMITHEMA_07555
TMWTHMA_1382
TMQTHMB_1382
TMXTHMC_1382
TPTTpet_1426
TNPTnap_1446
TRQTRQ2_1472
TNACTN_1234
THQT2812B_07355
THZCELL2_07430
THRTRQ7_07675
TLETlet_0926
TTATheth_0400
PHYAJ81_02195
TMETmel_0875
TAFTHA_1132
THPBG95_05115
THERY592_05195
TFEJYK00_03825
FNOFnod_0681
FPEFerpe_0469
FIANA23_02645
MPZMarpi_1304
MARNLN42_07005
DTNDTL3_0361
KOLKole_1045
KPFIX53_08385
CPOCOPRO5265_0630
CEXCSE_07090
DINSelin_1287
DDFDEFDS_P129
CNICalni_1110
CABYCabys_2003(rtcB)
DTHDICTH_1853
DTUDtur_0127
TYETHEYE_A1750
DTPJZK55_18670(rtcB)
NDENIDE2519
NMVNITMOv2_3246(rtcB)
NIONITINOP_0749(rtcB)
NJANSJP_3890(rtcB)
NKFNkreftii_000241
TIDThein_0246
TOPTOPB45_0200
TCMHL41_09115
THETF1847_06950
CTHITHC_0235
TAVG4V39_08180
TMAIFVE67_05215
NLIG3M70_02085
ALAMRT761_01161(rtcB)
BANABARAN1_0885(rtcB)
BIHBIP78_1017
MOXDAMO_1577
MJAMJ_0682
MFEMefer_0616
MVUMetvu_1561
MFSMFS40622_1498
MIFMetin_0800
MJHJH146_1216
MIGMetig_0681
MMPMMP1392
MMQMmarC5_0186
MMXMmarC6_1281
MMZMmarC7_0637
MMDGYY_07790
MMAKMMKA1_16160
MMAOMMOS7_14970
MMADMMJJ_14470(rtcB)
MAEMaeo_0134
MVNMevan_0703
MVOMvol_0961
MOKMetok_1141
METFCFE53_06310
MTHMTH_1597
MMGMTBMA_c01830
MWOMWSIV6_0141(rtcB)
MTEEMTTB_12520
METCMTCT_1456
METEtca_01546(rtcB)
METZMETMT2_0142
METKFVF72_03630
MTHMFZP57_00610
METJFZP68_05625
MSTMsp_0641
METBAW729_04565
MRUmru_0426 mru_1311
MSIMsm_0666
MEBAbm4_0216
MMILsm9_0302(rtcB)
MEYETL18_01295
MOLYLM1_0096
MAROMarbSA_09770
METVK4897_03920
MELMetbo_0556
MEWMSWAN_1826
METHMBMB1_1440(rtcB)
MFCBRM9_0668
MFIDSM1535_0639(rtcB)
MCUBMCBB_1701(rtcB)
MSUBBK009_06155
METNBK008_01695
METTCIT01_06620
METOCIT02_10835
MEMEHYG87_07380
MFVMfer_0490
MKAMK1682(rtcB)
AFUAF_0862
AFGAFULGI_00009450
APOArcpr_0802
AVEArcve_0987
ASTAsulf_02033
FPLFerp_1294
GACGACE_0692
GAHGAH_02018
PFUPF1615
PFIPFC_10530
PHOPH1602(PH1602)
PABPAB0383
PYNPNA2_0188
PYAPYCH_04230
PYSPy04_1491
PYCTQ32_08845
TKOTK0358
TONTON_0714
TGATGAM_1505
TSITSIB_1552
TBATERMP_00599
THEGQS_01315
THATAM4_1534
THMCL1_1978
TLTOCC_11789
THSTES1_0931
TNUBD01_1004
TEUTEU_10910
TGYX802_00405
THVADU37_CDS15980
TCHCHITON_1840
TPEPA0127_02520
TPIEA7C91_09700
TGGA3K92_03830
TCEA3L02_03795
TBSA3L01_04355
THHCDI07_04270
TSLA3L11_08380
TTDA3L14_06280
TPRFA3L09_07300
TRLA3L10_02220
TPAFA3L08_07550
THYA3L12_07725
TICFH039_08520
TCQTIRI35C_1128(rtcB)
THEMFPV09_01065
THEIK1720_00170
PPACPAP_02800
MBAMbar_A1252
MBYMSBRM_0351
MBWMSBRW_3473
MBARMSBR2_2031
MBAKMSBR3_2141
MACMA_0266
MMAMM_1538
MMAZMmTuc01_1602
MMJMSMAS_3130
MMACMSMAC_3149
MVCMSVAZ_0294
MEKMSKOL_0277
MLSMSLAZ_0080
METMMSMTP_3027
MEFMSWH1_0187
MEQMSWHS_0198
MSJMSSAC_0252
MSZMSSIH_0215
MSWMSSIT_0219
MTHRMSTHT_2025
MTHEMSTHC_1260
MHORMSHOH_3860
MFZAOB57_009440
MBUMbur_2207
MMETMCMEM_0383
MELOJ7W08_12045
MMHMmah_0438
MHAZBHR79_01315
MEVMetev_2065
MZHMzhil_1690
MPYMpsy_2320
MZIHWN40_10740
MHZMetho_0446
MTPMthe_1374
MCJMCON_2082
MHIMhar_0588
MHUMhun_3181
MRTJKHC33_00820
MLAMlab_0129
MEMMemar_1651
MBGBN140_1948
MEMAMMAB1_2517(rtcB)
MCHKMchiMG62_17500
MPIMpet_1701
MBNMboo_1792
MFOMetfor_1326
MPLMpal_1018
MPDMCP_2028
MEZMtc_2035
RCILRC484
HALVNG_1454C
HSLOE_3085R(rtcB)
HDLHALDL1_12410
HHBHhub_2827(rtcB)
HAGSJT689_07230
HABOJRZ79_05660
HNOLT974_10515
HLULT972_02040 LT972_03925
HANRLJ422_05910
HJEHacjB3_07335
HALHHTSR_0561
HHSRHSR6_0548
HSUHLASF_1437
HSFHLASA_1424
SALRFQU85_12110
HALREFA46_000460
HARAAArcS_0849(rtcB)
HAADMW046_00540 MW046_04435 MW046_10160
HALXM0R89_01220
HAXZM0R88_01170
HMArrnAC0783
HHIHAH_1430
HHNHISP_07305
HABSG26_15150
HTABVU17_06950
HALJG9465_08900 G9465_13090
HSINKDQ40_06340
NPHNP_2178A(rtcB1)
NMONmlp_1052(rtcB2) Nmlp_2687(rtcB1)
NHOHWV23_01175
NSALHWV07_01520
HUTHuta_1132 Huta_2758
HTIHTIA_1009 HTIA_2505
HALAHrd1104_05960
HMUHmuk_3106
HALZE5139_02775
HALLLC1Hm_2443(rtcB)
HAZPGBQ70_02775
HALIBV210_01795
HSNDV733_13805 DV733_14040
HDSHSR122_1982(rtcB) HSR122_2330(rtcB2)
HRRHZS55_15420
HPELHZS54_07025 HZS54_18455
HLTI7X12_17455 I7X12_20180
HARCHARCEL1_08755
HDOMUK72_13215
HWAHQ_1965A(rtcB)
HWCHqrw_2131(rtcB)
HVOHVO_2712(rtcB)
HMEHFX_0513(rtcB_1) HFX_2723(rtcB)
HGIABY42_13585
HALEG3A49_17250
HBOHbor_11750
HAQDU484_14135
HAJDU500_14165
HAERDU502_12280
HRAEI982_01250
HLMDV707_08155
HALMFCF25_05400
HLAHlac_2024
HALPDOS48_10675
HALBEKH57_14610
HEZZEO776_10100
HALQHrr1229_009835
HSSJ7656_05335
HSAIHPS36_10550
HAZZKI388_09415
HAEhalTADL_0189
HALNB4589_005810
HALGHUG10_03415
HALUHUG12_05060 HUG12_13505
HMPK6T50_01630
HREK6T36_01445
HRMK6T25_14965
HACBHbl1158_08545
HDFAArcSl_1732(rtcB) AArcSl_2679(rtcB2)
HAHHalar_1815
HTUHtur_2560
HDABB347_07495
HSALJMJ58_16020
HLOJ0X27_14550
HAKZJ0X25_18615
NMGNmag_0414(rtcB1) Nmag_4093(rtcB2)
HXAHalxa_0751
NATNJ7G_1087
NPENatpe_1666
NVRFEJ81_08590
NPLFGF80_03155
NAYHYG81_01115
HALYHYG82_04970
HJTDVR14_17815
NGENatgr_2668
HRUHalru_1761
NOUNatoc_1825
SALIL593_06610
SAIMK0C01_07665 K0C01_10740
HLRHALLA_15025
HLCCHINAEXTREME11190
NAJB1756_16485
NAGAArcMg_2075
NANAArc1_1602
NBGDV706_12040
NASGCU68_00050
SAWLNGM29_07755
NACAQV86_00410
MELUMTLP_03710
MEAMMU439_02205
TARTALC_00461
MAXMMALV_03870
MERMMINT_03530
MEARMpt1_c01880(rtcB)
MEUZKRP56_02035
MARCAR505_1406
ABIAboo_0966
ACFAciM339_1019
APEAPE_1758.1
ACJACAM_1104
SMRSmar_0985
SHCShell_1476
IHOIgni_0393
IISEYM_00515
DKADKAM_1210
DFDDesfe_1313
DMUDesmu_1201
TAGTagg_0797
THGTCELL_0298
HBUHbut_0518
PFMPyrfu_1301
PDLPyrde_0179
STOSTK_12920
SOHD1869_07485
SSOSSO0966
SOLSsol_1945
SSOASULA_1977
SSOLSULB_1978
SSOFSULC_1976
SSHIJ5U23_02510
SCASSACC_08530
SAISaci_1317
SACNSacN8_06420
SACRSacRon12I_06410
SACSSUSAZ_06290
SISLS215_1344
SIAM1425_1257
SIMM1627_1307
SIDM164_1241
SIYYG5714_1242
SINYN1551_1606
SIILD85_1369
SIHSiH_1202
SIRSiRe_1120
SICSiL_1117
SULABFU36_01590
SULEGFS03_07065
SULOGFS33_12475
SULLEWF20_08660
MSEMsed_1752
MCNMcup_0477
MHKDFR87_09900
MPRUDFR88_09475
MTENGWK48_02370
MJNMjAS7_2880
MEMJMJ1HA_1997
AHOAhos_1417
AMANB6F84_11545
ABRIDFR85_10900
ASULDFR86_09860
AAMBD1866_02020
ACIHHS5_28290
SACDHS1genome_1036
SAZOD1868_04250
CSTYKN1_24390
STEPIC006_1178
SAHSHS7_17940
PAIPAE0998
PISPisl_1219
PCLPcal_0141
PASPars_0172
PYRP186_2427
POGPogu_2307
TNETneu_0157
PYWPYWP30_00177
CMACmaq_1864
TTNTTX_1033
TUZTUZN_0719
VDIVdis_2242
VMOVMUT_0652
TPETpen_0269
THBN186_02250
TCBTCARB_1526
THFMA03_00180
THELIG193_06265
ACIASE86_05330
CLGCalag_0669
FFOFFONT_0754
NMRNmar_1453
NIRNSED_07985
NKRNKOR_07955
NIDNPIRD3C_2113(rtcB)
NINNADRNF5_0431(rtcB)
NIWNisw_06725
NCLC5F47_07660
NOXC5F49_07540
NUEC5F50_10860
NIPNsoK4_01020
NCTNMSP_0297(rtcB)
NICDSQ20_08595
CSYCENSYa_1073
NGANgar_c04520
NVNNVIE_015180
NEVNTE_02933
TAANMY3_00808(rtcB)
NFNNFRAN_1800(rtcB)
NCVNCAV_0536(rtcB)
CSUCSUB_C0047
NBVT478_0330
TAHSU86_008485
NIUDSQ19_01105 DSQ19_08145
NDVNDEV_1737(rtcB)
CCAINAS2_0232
KCRKcr_1407
BARBAOA66_0564(rtcB_1)
NEQNEQ078
NAANps_02110
MARHMia14_0602
FLTSv326_0284
MIYMicr_00401(rtcB_2)
NCONLC1Nh_1125(rtcB)
AGWQT03_C0001G0851
 » show all
Reference
1  [PMID:21757685]
  Authors
Tanaka N, Meineke B, Shuman S
  Title
RtcB, a novel RNA ligase, can catalyze tRNA splicing and HAC1 mRNA splicing in vivo.
  Journal
J Biol Chem 286:30253-7 (2011)
DOI:10.1074/jbc.C111.274597
  Sequence
[eco:b3421]
Reference
2  [PMID:21224389]
  Authors
Tanaka N, Shuman S
  Title
RtcB is the RNA ligase component of an Escherichia coli RNA repair operon.
  Journal
J Biol Chem 286:7727-31 (2011)
DOI:10.1074/jbc.C111.219022
  Sequence
[eco:b3421]
Reference
3  [PMID:22045815]
  Authors
Tanaka N, Chakravarty AK, Maughan B, Shuman S
  Title
Novel mechanism of RNA repair by RtcB via sequential 2',3'-cyclic phosphodiesterase and 3'-Phosphate/5'-hydroxyl ligation reactions.
  Journal
J Biol Chem 286:43134-43 (2011)
DOI:10.1074/jbc.M111.302133
Reference
4  [PMID:22320833]
  Authors
Desai KK, Raines RT
  Title
tRNA ligase catalyzes the GTP-dependent ligation of RNA with 3'-phosphate and 5'-hydroxyl termini.
  Journal
Biochemistry 51:1333-5 (2012)
DOI:10.1021/bi201921a
  Sequence
[pho:PH1602]
Reference
5  [PMID:22474365]
  Authors
Chakravarty AK, Subbotin R, Chait BT, Shuman S
  Title
RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates.
  Journal
Proc Natl Acad Sci U S A 109:6072-7 (2012)
DOI:10.1073/pnas.1201207109
Reference
6  [PMID:22730297]
  Authors
Chakravarty AK, Shuman S
  Title
The sequential 2',3'-cyclic phosphodiesterase and 3'-phosphate/5'-OH ligation steps of the RtcB RNA splicing pathway are GTP-dependent.
  Journal
Nucleic Acids Res 40:8558-67 (2012)
DOI:10.1093/nar/gks558
Reference
7  [PMID:24218597]
  Authors
Das U, Chakravarty AK, Remus BS, Shuman S
  Title
Rewriting the rules for end joining via enzymatic splicing of DNA 3'-PO4 and 5'-OH ends.
  Journal
Proc Natl Acad Sci U S A 110:20437-42 (2013)
DOI:10.1073/pnas.1314289110
Reference
8  [PMID:26385509]
  Authors
Desai KK, Beltrame AL, Raines RT
  Title
Coevolution of RtcB and Archease created a multiple-turnover RNA ligase.
  Journal
RNA 21:1866-72 (2015)
DOI:10.1261/rna.052639.115
Reference
9  [PMID:26858100]
  Authors
Maughan WP, Shuman S
  Title
Distinct Contributions of Enzymic Functional Groups to the 2',3'-Cyclic Phosphodiesterase, 3'-Phosphate Guanylylation, and 3'-ppG/5'-OH Ligation Steps of the Escherichia coli RtcB Nucleic Acid Splicing Pathway.
  Journal
J Bacteriol 198:1294-304 (2016)
DOI:10.1128/JB.00913-15
Other DBs
ExplorEnz - The Enzyme Database: 6.5.1.8
IUBMB Enzyme Nomenclature: 6.5.1.8
ExPASy - ENZYME nomenclature database: 6.5.1.8
BRENDA, the Enzyme Database: 6.5.1.8

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