KEGG   ENZYME: 7.1.3.1
Entry
EC 7.1.3.1                  Enzyme                                 
Name
H+-exporting diphosphatase;
H+-PPase;
proton-pumping pyrophosphatase;
vacuolar H+-pyrophosphatase;
hydrogen-translocating pyrophosphatase;
proton-pumping dihosphatase
Class
Translocases;
Catalysing the translocation of hydrons;
Linked to the hydrolysis of diphosphate
Sysname
diphosphate phosphohydrolase (H+-transporting)
Reaction(IUBMB)
diphosphate + H2O + H+[side 1] = 2 phosphate + H+[side 2]
Substrate
diphosphate [CPD:C00013];
H2O [CPD:C00001];
H+[side 1]
Product
phosphate [CPD:C00009];
H+[side 2]
Comment
This enzyme, found in plants and fungi, couples the energy from diphosphate hydrolysis to active proton translocation across the tonoplast into the vacuole. The enzyme acts cooperatively with cytosolic soluble diphosphatases to regulate the cytosolic diphosphate level.
History
EC 7.1.3.1 created 2018
Orthology
K23025  H+-translocating diphosphatase
Genes
ATHAT1G15690(AVP1) AT1G16780(VHP2;2) AT1G78920(VP2)
ALY9325283 9326182 9326251
CRB17895094 17895417 17899023
CSAT104703231 104703395 104714174 104714331 104740254 104740361 104752317 104752473 104755880 104755999 104774389 104778744 104778745
EUSEUTSA_v10006869mg EUTSA_v10018137mg EUTSA_v10018163mg
BRP103832369 103832483(AVP1-2) 103836019(AVP1-1) 103842889 103853151 103872357
BNA106346644 106354660 106354844 106367071 106381452 106381539 106381540 106381544 106387567 106403324 106403325 106414619 106430757 111197719 111207155
BOE106294603 106299969 106300469 106309512 106311519 106326947
RSZ108805087 108820134 108822185 108827356 108828450 108843556
THJ104808107 104812334 104812467 104813573 104815298 104826559
CPAP110807328 110815411 110821062 110826127
CIT102578049 102612154 102617625
CICCICLE_v10007524mg CICLE_v10013931mg CICLE_v10024946mg
PVY116105970 116107838 116120967 116140187
MINC123194156 123200302 123209173 123211449 123218102 123218770
TCC18588850 18595335 18595567 18600564
GRA105768017 105768790 105772855 105773126 105776918 105783195 105791042 105792472 105799109
GHI107889146 107891667 107893910 107897013 107901338 107906449 107912554 107925190 107930386 107933788 107962574 121205114 121212597 121217449 121217696 121225237 121229212 121230698
GAB108450768 108453029 108453143 108453215 108460448 108464253 108470008 108489322
DZI111274418 111275342 111277370 111278804 111280290 111294008 111296916 111300831 111303308
EGR104414666 104419828 104423194 104423279 104428252 104430494 104437836 104438616 104439977 104439978 104439979 104439980 104439983 104439987 104452526 104454834
GMX100775864 100784465 100787805 100794166 100803691 100812548
GSJ114373752 114402910 114417869 114418087 114422468 114422549
PVUPHAVU_003G171500g PHAVU_010G164900g
VRA106768298 106779108
VAR108320596 108345536
VUN114166707 114176081 114176955 114176956
CCAJ109807586 109807727 109807940 109817379
APRC113847663 113854116 113857037 113857281 113871089
MTRMTR_4g005280 MTR_4g115970
CAM101514301 101515471
LJALj3g3v2027530.1(Lj3g3v2027530.1) Lj3g3v2027530.2(Lj3g3v2027530.2) Lj3g3v2172730.1(Lj3g3v2172730.1) Lj4g3v1936570.1(Lj4g3v1936570.1) Lj4g3v1936570.2(Lj4g3v1936570.2)
ADU107461422 107463769 107465246 107482363
AIP107614690 107614691 107617688 107617887 107635834 107640576
AHF112701447 112709778 112710745 112723337 112740786 112775484 112775929 112776816 112795506
LANG109339792 109346005 109350629 109354702 109358489 109362215
FVE101303836 101308398 101314105 101314765
RCN112186295 112188033 112189182 112193806
PPER18771632 18772546 18782476 18783468
PMUM103327448 103328067 103341138 103344065
PAVI110752644 110761656 110762863 110767435
PDUL117620659 117620886 117629678 117634117
MDM103415567 103423547 103426080 103433876 103436160 103443357 103451968
PXB103927435 103927764 103928924 103930851 103949175 103953877 103962309 103967655
ZJU107407705 107410535 107411770
MNT21384663 21387616 21396996 21407647 21408417
CSV101205277 101217198 101222673(VP)
CMO103487401 103494311 103500610
BHJ120070563 120079565 120085968
MCHA111007149 111022029 111023264
CMAX111465445 111485119 111488556 111496068
CMOS111436191 111444356 111456089 111461438
CPEP111779886 111792635 111798289 111806788
RCU8259946 8263849 8269813 8282702
JCU105634813 105641261 105646133 105647416
HBR110639327 110640802 110641816 110648209 110649406 110665718 110665937 110671337 110671429
MESC110599668 110613840 110617341 110617500 110619939 110622984 110625528
POP112324981 18098598 18099906 18111071 7469460 7478904 7497772
PEU105121078 105122668 105125152 105131688 105134291 105141142
PALZ118032617 118047668 118052052 118060211 118060942 118062205
JRE108987724 108995630 109005008 109005438 109012858 109019074
QSU111988386 112024341 112028747 112034339
QLO115973796 115979923 115981712 115989622 115991818
TWL119997292 120004774 120007657 120009640 120010796 120011470
VVI100232894(VPP2) 100233104 100247980 100256710
VRI117921486 117922148 117922157 117925041 117929518
SLY101246569 101253082(LeVP3) 101259424(VP2) 101261420 101263674 543761(VP1)
SPEN107005322 107014423 107017917 107021063 107025645 107025768
SOT102579479 102583477 102586995 102600043 102604491
CANN107839687 107840797 107862038 107867620 107876025 107877721
NTA107761395(ppa) 107774827 107776076 107776628(ppa) 107778409 107794544 107799531 107809014 107813411 107814653 107815824(ppa)
NSY104215140 104215382 104216758 104229096 104239144 104242725
NTO104090166 104091471 104094216 104105034 104118698 104120133
NAU109208365 109223323 109234434 109237019 109241675
INI109147415 109170124 109176472 109178777
ITR116002099 116007896 116013260 116025378
SIND105158354 105162240 105164876 105166431 105174795
OEU111390712 111391797 111397433 111397435 111402268 111403939 111405203
EGT105948827 105955010 105960664 105972331 105975782
SSPL121746977 121749585 121752076 121775354 121777618 121796172 121799915 121805061
HAN110877370 110886632 110893917 110916370 110935741 110939579
ECAD122587009 122593437 122596225 122606687 122607663
LSV111877800 111881873 111898903 111899343 111908368 111910058
CCAV112500830 112505799 112506832 112509415 112511102 112516456 112516765
DCR108195861 108209376 108209970 108214208 108217725 108226560
CSIN114266246 114271697 114290771 114295637 114305513 114308480 114319251
BVG104901923 104904547 104908681
SOE110785597 110793903 110801873
CQI110687940 110698623 110708026 110725552 110726793
NNU104588605 104592540 104598796 104601609
MING122071997 122073969 122081104 122081557
TSS122652803 122661378 122668067
PSOM113299984 113318088 113348954 113350208 113358789
NCOL116248776 116250144 116252884 116254281 116263769 116264291
OSA4326846 4328526 4329579 4331044 4337864 4340298 4341645
DOSAOs01t0337500-00(Os01g0337500) Os02t0537900-01(Os02g0537900) Os02t0802500-01(Os02g0802500) Os05t0156900-01(Os05g0156900) Os06t0178900-01(Os06g0178900) Os06t0644200-01(Os06g0644200)
OBR102704490 102709145 102711708 102712041 102716422 102716473 102719389
BDI100827063 100831519 100832532 100833667 100836640
ATS109751043 109771576 109774055 109777267 109787080
TDC119278836 119318192 119323061 119327172 119329055 119331368 119336913 119341335 119343077 119366471
TAES100136960 123039083 123055218 123113270 123128671 123132401 123138732 123145805 123149539 123158100 123159822 123164763 123180583 123181973 543450
TUA125514977 125517315 125520334 125550889
SBI110430849 8058399 8065790 8070111 8075312 8076017 8079416 8084655
ZMA100126542 100280334 100286099 100382506 101027208 103635138 103650470 103654862 542328
SITA101758107 101761609 101763159 101767008 101768410 101774456 101780777 101780838
SVS117838460 117845055 117847910 117848664 117852914 117852966 117855316 117865337
PVIR120645252 120654873 120657510 120665759 120667261 120670087 120671284 120676010 120697501 120698994 120702796 120704042 120706829
PHAI112874098 112884273 112885752 112886604 112890035 112891165 112891576 112901085
PDA103698431 103706475 103710117 103711472 103712654 103715891 103720114
EGU105033049 105039062 105042697 105049421 105050114 105052596
MUS103972488 103978161 103984832 103985418 103986815 103989956 103992412 103993690 103998428
DCT110100315 110107993 110115075
PEQ110021133 110021993 110031869
AOF109822824 109825116 109835594 109838127 109841169
ATR18431217 18440749 18442574
SMOSELMODRAFT_156843 SELMODRAFT_157618 SELMODRAFT_270204 SELMODRAFT_270614
PPP112284684 112284687 112286837 112287610 112294453
CRECHLRE_09g394436v5
VCNVOLCADRAFT_76494
CSLCOCSUDRAFT_29300 COCSUDRAFT_36403
CVRCHLNCDRAFT_143568 CHLNCDRAFT_32356
APROF751_4161
OLUOSTLU_31307 OSTLU_39838
OTAOT_ostta01g00980 OT_ostta04g03800
BPGBathy01g00880 Bathy08g03020
MISMICPUN_107016 MICPUN_94241 MICPUN_97152
MPPMICPUCDRAFT_34063 MICPUCDRAFT_45236 MICPUCDRAFT_46773
CMECYME_CMO102C
GSLGasu_15740 Gasu_15900 Gasu_28190
PFAPF3D7_1235200 PF3D7_1456800
PFDPFDG_00012 PFDG_04702
PFHPFHG_00686 PFHG_02084
PREIPRSY57_1234400 PRSY57_1456100
PGABPGSY75_1235200 PGSY75_1456800
PYOPY17X_1324300 PY17X_1452300
PCBPCHAS_132380(PC000445.03.0) PCHAS_145210(PC000015.02.0)
PBEPBANKA_1320500 PBANKA_1449800
PVVPVVCY_1302200 PVVCY_1405190
PKNPKNH_1225000 PKNH_1454900
PVXPVX_100710 PVX_117625
PCYPCYB_125830 PCYB_146090
TGOTGME49_248670
TETTTHERM_000773801 TTHERM_00218790 TTHERM_00735340
PTMGSPATT00014977001 GSPATT00017042001 GSPATT00020810001 GSPATT00021301001 GSPATT00021886001 GSPATT00027681001 GSPATT00031717001 GSPATT00032758001 GSPATT00036772001 GSPATT00037050001
SMINv1.2.024117.t1(symbB.v1.2.024117.t1) v1.2.024117.t2(symbB.v1.2.024117.t2) v1.2.032240.t1(symbB.v1.2.032240.t1)
PTIPHATRDRAFT_26190 PHATR_21183
FCYFRACYDRAFT_207890
TPSTHAPSDRAFT_39520
AAFAURANDRAFT_29608(VPP1) AURANDRAFT_70885(VPP2)
PIFPITG_05615 PITG_06731
PSOJPHYSODRAFT_255048 PHYSODRAFT_297061
SPARSPRG_03678 SPRG_05568
EHXEMIHUDRAFT_415047 EMIHUDRAFT_51239 EMIHUDRAFT_75032
GTTGUITHDRAFT_145095 GUITHDRAFT_156810 GUITHDRAFT_157618 GUITHDRAFT_157894 GUITHDRAFT_162896
TBRTb927.4.4380 Tb927.8.7980
TBGTbgDal_IV4470 TbgDal_VIII8300
TCR510773.20 511385.30
LMALMJF_31_1220
LIFLINJ_31_1240
LDOLDBPK_311240
LMILMXM_30_1220
LBZLBRM_31_1450
LPANLPMP_311140
NGRNAEGRDRAFT_70050
 » show all
Reference
1  [PMID:16664761]
  Authors
Rea PA, Poole RJ
  Title
Chromatographic resolution of h-translocating pyrophosphatase from h-translocating ATPase of higher plant tonoplast.
  Journal
Plant Physiol 81:126-9 (1986)
DOI:10.1104/pp.81.1.126
Reference
2  [PMID:16667022]
  Authors
Sarafian V, Poole RJ
  Title
Purification of an h-translocating inorganic pyrophosphatase from vacuole membranes of red beet.
  Journal
Plant Physiol 91:34-8 (1989)
DOI:10.1104/pp.91.1.34
Reference
3  [PMID:2479537]
  Authors
Hedrich R, Kurkdjian A, Guern J, Flugge UI
  Title
Comparative studies on the electrical properties of the H+ translocating ATPase and pyrophosphatase of the vacuolar-lysosomal compartment.
  Journal
EMBO J 8:2835-41 (1989)
DOI:10.1002/j.1460-2075.1989.tb08430.x
Reference
4  [PMID:29691313]
  Authors
Segami S, Tomoyama T, Sakamoto S, Gunji S, Fukuda M, Kinoshita S, Mitsuda N, Ferjani A, Maeshima M
  Title
Vacuolar H(+)-Pyrophosphatase and Cytosolic Soluble Pyrophosphatases Cooperatively Regulate Pyrophosphate Levels in Arabidopsis thaliana.
  Journal
Plant Cell 30:1040-1061 (2018)
DOI:10.1105/tpc.17.00911
  Sequence
[ath:AT1G15690]
Other DBs
ExplorEnz - The Enzyme Database: 7.1.3.1
IUBMB Enzyme Nomenclature: 7.1.3.1
ExPASy - ENZYME nomenclature database: 7.1.3.1
BRENDA, the Enzyme Database: 7.1.3.1

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