KEGG   ENZYME: 7.2.1.4
Entry
EC 7.2.1.4                  Enzyme                                 
Name
tetrahydromethanopterin S-methyltransferase;
tetrahydromethanopterin methyltransferase;
mtrA-H (gene names);
cmtA (gene name);
N5-methyltetrahydromethanopterin---coenzyme M methyltransferase;
5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethanesulfonate 2-methyltransferase
Class
Translocases;
Catalysing the translocation of inorganic cations;
Linked to oxidoreductase reactions
Sysname
5-methyl-5,6,7,8-tetrahydromethanopterin:CoM 2-methyltransferase (Na+-transporting)
Reaction(IUBMB)
5-methyl-5,6,7,8-tetrahydromethanopterin + CoM + 2 Na+[side 1] = 5,6,7,8-tetrahydromethanopterin + 2-(methylsulfanyl)ethane-1-sulfonate + 2 Na+[side 2] [RN:R04347]
Reaction(KEGG)
R04347;
(other) R12291
Substrate
5-methyl-5,6,7,8-tetrahydromethanopterin [CPD:C04488];
CoM [CPD:C03576];
Na+[side 1]
Product
5,6,7,8-tetrahydromethanopterin [CPD:C01217];
2-(methylsulfanyl)ethane-1-sulfonate [CPD:C03920];
Na+[side 2]
Comment
Involved in the formation of methane from CO2 in methanogenic archaea. The reaction involves the export of one or two sodium ions. The enzyme from the archaeon Methanobacterium thermoautotrophicum is a membrane-associated multienzyme complex composed of eight different subunits, and contains a 5'-hydroxybenzimidazolyl-cobamide cofactor, to which the methyl group is attached during the transfer. A soluble enzyme that is induced by the presence of CO has been reported as well [6].
History
EC 7.2.1.4 created 1989 as EC 2.1.1.86, modified 2000, modified 2017, transferred 2024 to EC 7.2.1.4
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K00577  tetrahydromethanopterin S-methyltransferase subunit A
K00578  tetrahydromethanopterin S-methyltransferase subunit B
K00579  tetrahydromethanopterin S-methyltransferase subunit C
K00580  tetrahydromethanopterin S-methyltransferase subunit D
K00581  tetrahydromethanopterin S-methyltransferase subunit E
K00582  tetrahydromethanopterin S-methyltransferase subunit F
K00583  tetrahydromethanopterin S-methyltransferase subunit G
K00584  tetrahydromethanopterin S-methyltransferase subunit H
Genes
MEIN: methR_P3792
TEE: Tel_11320
SVA: SVA_2695
DAR: Daro_2280
MCH: Mchl_5727
HMC: HYPMC_2275
CID: P73_3963
MAG: amb1203
DTI: Desti_0878 Desti_5438 Desti_5449
ACA: ACP_1207
LFC: LFE_1243
LFI: LFML04_0654
DED: DHBDCA_p634
DEC: DCF50_p692
DRS: DEHRE_07520
DKU: Desku_0058
FWA: DCMF_06005 DCMF_12455
TJR: TherJR_0145 TherJR_0981
TEB: T8CH_1641
TOC: Toce_1535
SVU: B1H20_29990
SCAL: I6J39_29795
CALL: OZ401_003859
MJA: MJ_0847 MJ_0848 MJ_0849 MJ_0850 MJ_0851 MJ_0852 MJ_0853 MJ_0854
MFE: Mefer_0939 Mefer_0940 Mefer_0941 Mefer_0942 Mefer_0943 Mefer_0944 Mefer_0945 Mefer_0946
MVU: Metvu_0150 Metvu_0151 Metvu_0152 Metvu_0153 Metvu_0154 Metvu_0155 Metvu_0156 Metvu_0157
MFS: MFS40622_1307 MFS40622_1308 MFS40622_1309 MFS40622_1310 MFS40622_1311 MFS40622_1312 MFS40622_1313 MFS40622_1314
MIF: Metin_0273 Metin_0274 Metin_0275 Metin_0276 Metin_0277 Metin_0278 Metin_0279 Metin_0280
MJH: JH146_1047 JH146_1048 JH146_1049 JH146_1050 JH146_1051 JH146_1052 JH146_1053 JH146_1054 JH146_1055
MESG: MLAUSG7_0345(mtrH) MLAUSG7_0346(mtrG) MLAUSG7_0348(mtrA) MLAUSG7_0349(mtrB) MLAUSG7_0350(mtrC) MLAUSG7_0351(mtrD) MLAUSG7_0352(mtrE)
MESA: MLASG1_1524(mtrH) MLASG1_1525(mtrG) MLASG1_1527(mtrA) MLASG1_1528(mtrB) MLASG1_1529(mtrC) MLASG1_1530(mtrD) MLASG1_1531(mtrE)
MIG: Metig_1238 Metig_1239 Metig_1240 Metig_1241 Metig_1242 Metig_1243 Metig_1244 Metig_1245
MMP: MMP1560(mtrE) MMP1561(mtrD) MMP1562(mtrC) MMP1563(mtrB) MMP1564(mtrA) MMP1565(or900) MMP1566(mtrG) MMP1567(mtrH)
MMQ: MmarC5_0009 MmarC5_0010 MmarC5_0011 MmarC5_0012 MmarC5_0013 MmarC5_0014 MmarC5_0015 MmarC5_0016
MMX: MmarC6_1103 MmarC6_1104 MmarC6_1105 MmarC6_1106 MmarC6_1107 MmarC6_1108 MmarC6_1109 MmarC6_1110
MMZ: MmarC7_0807 MmarC7_0808 MmarC7_0809 MmarC7_0810 MmarC7_0811 MmarC7_0812 MmarC7_0813 MmarC7_0814
MMD: GYY_08650 GYY_08655 GYY_08660 GYY_08665 GYY_08670 GYY_08675 GYY_08680 GYY_08685 GYY_08690
MMAK: MMKA1_17900(mtrE) MMKA1_17910(mtrD) MMKA1_17920(mtrC) MMKA1_17930(mtrB) MMKA1_17940(mtrA) MMKA1_17950(mtrA) MMKA1_17960(mtrG) MMKA1_17970(mtrH)
MMAO: MMOS7_16720(mtrE) MMOS7_16730(mtrD) MMOS7_16740(mtrC) MMOS7_16750(mtrB) MMOS7_16760(mtrA) MMOS7_16770(mtrA) MMOS7_16780(mtrG) MMOS7_16790(mtrH)
MMAD: MMJJ_12690(mtrH) MMJJ_12700(mtrG) MMJJ_12710(mtrA1) MMJJ_12720(mtrA2) MMJJ_12730(mtrB) MMJJ_12740(mtrC) MMJJ_12750(mtrD) MMJJ_12760(mtrE)
MAE: Maeo_1269 Maeo_1270 Maeo_1271 Maeo_1272 Maeo_1273 Maeo_1274 Maeo_1275 Maeo_1276
MVN: Mevan_0873 Mevan_0874 Mevan_0875 Mevan_0876 Mevan_0877 Mevan_0878 Mevan_0879 Mevan_0880
MVO: Mvol_1129 Mvol_1130 Mvol_1131 Mvol_1132 Mvol_1133 Mvol_1134 Mvol_1135 Mvol_1136
MOK: Metok_0948 Metok_0949 Metok_0950 Metok_0951 Metok_0952 Metok_0953 Metok_0954 Metok_0955
METF: CFE53_01150 CFE53_01155 CFE53_01160 CFE53_01170 CFE53_01175 CFE53_01180 CFE53_01185
MTH: MTH_1062 MTH_1156 MTH_1157 MTH_1158 MTH_1159 MTH_1160 MTH_1161 MTH_1162 MTH_1163
MMG: MTBMA_c14500 MTBMA_c15400(mtrH) MTBMA_c15410(mtrG) MTBMA_c15420(mtrF) MTBMA_c15430(mtrA) MTBMA_c15440(mtrB) MTBMA_c15450(mtrC1) MTBMA_c15460(mtrD) MTBMA_c15470(mtrE)
MWO: MWSIV6_1448(mtrA2) MWSIV6_1548(mtrH) MWSIV6_1549(mtrG) MWSIV6_1550(mtrF) MWSIV6_1551(mtrA1) MWSIV6_1552(mtrB) MWSIV6_1553(mtrC) MWSIV6_1554(mtrD) MWSIV6_1555(mtrE)
MTEE: MTTB_02590 MTTB_02600 MTTB_02610 MTTB_02620 MTTB_02630 MTTB_02640 MTTB_02650 MTTB_02660
METC: MTCT_0963 MTCT_1050 MTCT_1051 MTCT_1052 MTCT_1053 MTCT_1054 MTCT_1055 MTCT_1056 MTCT_1057
METE: tca_01026 tca_01113 tca_01114 tca_01115 tca_01116 tca_01117 tca_01118 tca_01119 tca_01120
METZ: METMT2_1164 METMT2_1165 METMT2_1166 METMT2_1167 METMT2_1168 METMT2_1169 METMT2_1170 METMT2_1171
METK: FVF72_05770(mtrE) FVF72_05775(mtrD) FVF72_05780(mtrC) FVF72_05785 FVF72_05790(mtrA) FVF72_05795(mtrF) FVF72_05800(mtrG) FVF72_05805(mtrH) FVF72_06280(mtrA)
MTHM: FZP57_06935(mtrA) FZP57_07415(mtrH) FZP57_07420(mtrG) FZP57_07425(mtrF) FZP57_07430(mtrA) FZP57_07435(mtrB) FZP57_07440(mtrC) FZP57_07445(mtrD) FZP57_07450(mtrE)
METJ: FZP68_03225(mtrE) FZP68_03230(mtrD) FZP68_03235(mtrC) FZP68_03240 FZP68_03245(mtrA) FZP68_03250(mtrF) FZP68_03255(mtrG) FZP68_03260(mtrH) FZP68_03700(mtrA)
MST: Msp_0300(mtrE) Msp_0301(mtrD) Msp_0302(mtrC) Msp_0303(mtrB) Msp_0304(mtrA) Msp_0305(mtrF) Msp_0306(mtrG) Msp_0307(mtrH)
METB: AW729_05600 AW729_05605 AW729_05610 AW729_05615 AW729_05625 AW729_05630 AW729_05635
MEIS: PXD04_05300(mtrE) PXD04_05305(mtrD) PXD04_05310(mtrC) PXD04_05315(mtrB) PXD04_05320(mtrA) PXD04_05325 PXD04_05330(mtrG) PXD04_05335(mtrH)
MRU: mru_0441(mtrA2) mru_1916(mtrH) mru_1917(mtrG) mru_1918(mtrF) mru_1919(mtrA1) mru_1920(mtrB) mru_1921(mtrC) mru_1922(mtrD) mru_1923(mtrE)
MSI: Msm_0627 Msm_1007 Msm_1008 Msm_1009 Msm_1010 Msm_1011 Msm_1012 Msm_1013 Msm_1014
MEB: Abm4_1518(mtrH) Abm4_1519(mtrG) Abm4_1520(mtrF) Abm4_1521(mtrA) Abm4_1522(mtrB) Abm4_1523(mtrC) Abm4_1524(mtrD) Abm4_1525(mtrE)
MMIL: sm9_0659(mtrA2) sm9_1915(mtrH2) sm9_2019(mtrH1) sm9_2020(mtrG) sm9_2021(mtrF) sm9_2022(mtrA1) sm9_2023(mtrB) sm9_2024(mtrC) sm9_2025(mtrD) sm9_2026(mtrE)
MEYE: TL18_08555 TL18_09280 TL18_09285 TL18_09290 TL18_09295 TL18_09300 TL18_09305 TL18_09310 TL18_09315
MOL: YLM1_0116 YLM1_0712 YLM1_1370 YLM1_1371 YLM1_1372 YLM1_1373 YLM1_1374 YLM1_1375 YLM1_1376 YLM1_1377 YLM1_1378
MARO: MarbSA_15430 MarbSA_15440 MarbSA_15450 MarbSA_15460 MarbSA_15470 MarbSA_15480 MarbSA_15490 MarbSA_15500
METV: K4897_03705(mtrH) K4897_06395(mtrE) K4897_06400(mtrD) K4897_06405(mtrC) K4897_06410 K4897_06415(mtrA) K4897_06420 K4897_06425(mtrG) K4897_06430(mtrH)
MEL: Metbo_0354 Metbo_0355 Metbo_0356 Metbo_0357 Metbo_0358 Metbo_0359 Metbo_0360 Metbo_0361
MEW: MSWAN_2048 MSWAN_2049 MSWAN_2050 MSWAN_2051 MSWAN_2052 MSWAN_2053 MSWAN_2054 MSWAN_2055
METH: MBMB1_0243(mtrA2) MBMB1_1674(mtrH) MBMB1_1675 MBMB1_1676(mtrF) MBMB1_1677(mtrA1) MBMB1_1678 MBMB1_1679(mtrC) MBMB1_1680(mtrD) MBMB1_1681(mtrE)
MFC: BRM9_0927(mtrH) BRM9_0928(mtrG) BRM9_0929(mtrF) BRM9_0930(mtrA1) BRM9_0931(mtrB) BRM9_0932(mtrC) BRM9_0933(mtrD) BRM9_0934(mtrE) BRM9_1713(mtrA2) BRM9_2057(mtrA3)
MFI: DSM1535_0897(mtrH) DSM1535_0898 DSM1535_0899 DSM1535_0900(mtrA1) DSM1535_0901 DSM1535_0902(mtrC) DSM1535_0903 DSM1535_0904(mtrE) DSM1535_1631(mtrA2)
MCUB: MCBB_1144(mtrA2) MCBB_1977(mtrH) MCBB_1978(mtrG) MCBB_1979(mtrF) MCBB_1980(mtrA1) MCBB_1981(mtrB) MCBB_1982(mtrC) MCBB_1983(mtrD) MCBB_1984(mtrE)
MSUB: BK009_07365 BK009_07370 BK009_07375 BK009_07380 BK009_07385 BK009_07390 BK009_07395 BK009_07400
METN: BK008_00460 BK008_03020 BK008_03025 BK008_03030 BK008_03035 BK008_03040 BK008_03045 BK008_03050 BK008_03055
METT: CIT01_00975(mtrA) CIT01_03590(mtrH) CIT01_03595(mtrG) CIT01_03600(mtrF) CIT01_03605(mtrA) CIT01_03610(mtrB) CIT01_03615(mtrC) CIT01_03620(mtrD) CIT01_03625
METO: CIT02_05770(mtrA) CIT02_09485(mtrE) CIT02_09490(mtrD) CIT02_09495(mtrC) CIT02_09500 CIT02_09505(mtrA) CIT02_09510(mtrF) CIT02_09515(mtrG) CIT02_09520(mtrH)
MEME: HYG87_04945(mtrH) HYG87_04950(mtrG) HYG87_04955(mtrF) HYG87_04960(mtrA) HYG87_04965(mtrB) HYG87_04970(mtrC) HYG87_04975(mtrD) HYG87_04980
MFEG: GCM10025860_02740 GCM10025860_02750 GCM10025860_02760 GCM10025860_02770 GCM10025860_02780 GCM10025860_02790 GCM10025860_02800(mtrD) GCM10025860_02810 GCM10025860_15550
MEER: NKF70_05190(mtrH) NKF70_05195(mtrG) NKF70_05200(mtrF) NKF70_05210(mtrB) NKF70_05215(mtrC) NKF70_05220(mtrD) NKF70_05225(mtrE)
MFV: Mfer_0072 Mfer_0776 Mfer_0777 Mfer_0778 Mfer_0779 Mfer_0780 Mfer_0781 Mfer_0782 Mfer_0783
MKA: MK0656(mtrE) MK0657(mtrD) MK0658(mtrC) MK0659(mtrB) MK0660(mtrA) MK0661(mtrG) MK0662(mtrH) MK1485(mtrF)
AST: Asulf_00600
FPL: Ferp_0136 Ferp_1749
GAC: GACE_1353
GAH: GAH_01245
MBA: Mbar_A0410 Mbar_A1255 Mbar_A1256 Mbar_A1257 Mbar_A1258 Mbar_A1259 Mbar_A1260 Mbar_A1261 Mbar_A1262 Mbar_A1713 Mbar_A2072 Mbar_A2073
MBY: MSBRM_0353 MSBRM_0354 MSBRM_0355 MSBRM_0356 MSBRM_0357 MSBRM_0358 MSBRM_0359 MSBRM_0360 MSBRM_0612 MSBRM_2435 MSBRM_2436 MSBRM_2967
MBW: MSBRW_0590 MSBRW_2666 MSBRW_2667 MSBRW_3022 MSBRW_3462 MSBRW_3463 MSBRW_3464 MSBRW_3465 MSBRW_3466 MSBRW_3467 MSBRW_3468 MSBRW_3469
MBAR: MSBR2_1768 MSBR2_2022 MSBR2_2023 MSBR2_2024 MSBR2_2025 MSBR2_2026 MSBR2_2027 MSBR2_2028 MSBR2_2029 MSBR2_2400 MSBR2_2401 MSBR2_2928
MBAK: MSBR3_0127 MSBR3_2143 MSBR3_2144 MSBR3_2145 MSBR3_2146 MSBR3_2147 MSBR3_2148 MSBR3_2149 MSBR3_2150 MSBR3_2456 MSBR3_2457
MAC: MA_0269(mtrH) MA_0270(mtrG) MA_0271(mtrF) MA_0272(mtrA) MA_0273(mtrB) MA_0274(mtrC) MA_0275(mtrD) MA_0276(mtrE) MA_1804(mtxH) MA_1805(mtxA)
MMA: MM_0255 MM_0256 MM_1540 MM_1541 MM_1542 MM_1543 MM_1544 MM_1545 MM_1546 MM_1547 MM_2251
MMAZ: MmTuc01_0261 MmTuc01_0262 MmTuc01_1605 MmTuc01_1606 MmTuc01_1607 MmTuc01_1608 MmTuc01_1609 MmTuc01_1610 MmTuc01_1611 MmTuc01_1612 MmTuc01_2304
MMJ: MSMAS_1045 MSMAS_1046 MSMAS_2444 MSMAS_3121 MSMAS_3122 MSMAS_3123 MSMAS_3124 MSMAS_3125 MSMAS_3126 MSMAS_3127 MSMAS_3128
MMAC: MSMAC_2003 MSMAC_2399 MSMAC_2402 MSMAC_3140 MSMAC_3141 MSMAC_3142 MSMAC_3143 MSMAC_3144 MSMAC_3145 MSMAC_3146 MSMAC_3147
MVC: MSVAZ_0285 MSVAZ_0286 MSVAZ_0287 MSVAZ_0288 MSVAZ_0289 MSVAZ_0290 MSVAZ_0291 MSVAZ_0292 MSVAZ_0402 MSVAZ_0726 MSVAZ_0727 MSVAZ_3003
MEK: MSKOL_0268 MSKOL_0269 MSKOL_0270 MSKOL_0271 MSKOL_0272 MSKOL_0273 MSKOL_0274 MSKOL_0275 MSKOL_0388 MSKOL_0709 MSKOL_0710
MLS: MSLAZ_0071 MSLAZ_0072 MSLAZ_0073 MSLAZ_0074 MSLAZ_0075 MSLAZ_0076 MSLAZ_0077 MSLAZ_0078 MSLAZ_1028 MSLAZ_2034
METM: MSMTP_1078 MSMTP_1079 MSMTP_2101 MSMTP_3017 MSMTP_3018 MSMTP_3019 MSMTP_3020 MSMTP_3021 MSMTP_3022 MSMTP_3023 MSMTP_3024
MEF: MSWH1_0189 MSWH1_0190 MSWH1_0191 MSWH1_0192 MSWH1_0193 MSWH1_0194 MSWH1_0195 MSWH1_0196 MSWH1_1167
MEQ: MSWHS_0200 MSWHS_0201 MSWHS_0202 MSWHS_0203 MSWHS_0204 MSWHS_0205 MSWHS_0206 MSWHS_0207 MSWHS_1242
MSJ: MSSAC_0254 MSSAC_0255 MSSAC_0256 MSSAC_0257 MSSAC_0258 MSSAC_0259 MSSAC_0260 MSSAC_0261 MSSAC_2649 MSSAC_2650
MSZ: MSSIH_0217 MSSIH_0218 MSSIH_0219 MSSIH_0220 MSSIH_0221 MSSIH_0222 MSSIH_0223 MSSIH_0224 MSSIH_2233 MSSIH_2234
MSW: MSSIT_0221 MSSIT_0222 MSSIT_0223 MSSIT_0224 MSSIT_0225 MSSIT_0226 MSSIT_0227 MSSIT_0228 MSSIT_2195 MSSIT_2196
MTHR: MSTHT_0017 MSTHT_0018 MSTHT_0918 MSTHT_2016 MSTHT_2017 MSTHT_2018 MSTHT_2019 MSTHT_2020 MSTHT_2021 MSTHT_2022 MSTHT_2023
MTHE: MSTHC_0710 MSTHC_0711 MSTHC_1262 MSTHC_1263 MSTHC_1264 MSTHC_1265 MSTHC_1266 MSTHC_1267 MSTHC_1268 MSTHC_1269
MHOR: MSHOH_1015 MSHOH_1253 MSHOH_1254 MSHOH_3851 MSHOH_3852 MSHOH_3853 MSHOH_3854 MSHOH_3855 MSHOH_3856 MSHOH_3857 MSHOH_3858
MFZ: AOB57_002455 AOB57_002460(mtrH) AOB57_009395 AOB57_009400(mtrD) AOB57_009405(mtrC) AOB57_009410 AOB57_009415(mtrA) AOB57_009420 AOB57_009425(mtrG) AOB57_009430(mtrH)
MHAB: RSJ42_02660 RSJ42_03095(mtrH) RSJ42_03100 RSJ42_17215(mtrH) RSJ42_17220(mtrG) RSJ42_17225 RSJ42_17230(mtrA) RSJ42_17235 RSJ42_17240(mtrC) RSJ42_17245(mtrD) RSJ42_17250(mtrE)
MBU: Mbur_1518(mtrH) Mbur_1519(mtrG) Mbur_1520(mtrF) Mbur_1521(mtrA) Mbur_1522(mtrB) Mbur_1523(mtrC) Mbur_1524(mtrD) Mbur_1525(mtrE) Mbur_2244
MMET: MCMEM_0396 MCMEM_0397 MCMEM_1982 MCMEM_1983 MCMEM_1984 MCMEM_1985 MCMEM_1986 MCMEM_1987 MCMEM_1988 MCMEM_1989
MELO: J7W08_08800(mtrE) J7W08_08805(mtrD) J7W08_08810 J7W08_08815 J7W08_08820 J7W08_08825 J7W08_08830(mtrG) J7W08_08835(mtrH) J7W08_12175 J7W08_12180(mtrH)
MMH: Mmah_0402 Mmah_0403 Mmah_1285 Mmah_1776 Mmah_1777 Mmah_1778 Mmah_1779 Mmah_1780 Mmah_1781 Mmah_1782 Mmah_1783
MHAZ: BHR79_01480 BHR79_01485 BHR79_04755 BHR79_04760 BHR79_04765 BHR79_04770 BHR79_04775 BHR79_04780 BHR79_04785 BHR79_04790
MPOT: BKM01_00880 BKM01_00885 BKM01_00890 BKM01_00895 BKM01_00900 BKM01_00905 BKM01_00910 BKM01_00915 BKM01_06960 BKM01_06965
MEV: Metev_1386 Metev_1388 Metev_2016 Metev_2017 Metev_2018 Metev_2019 Metev_2020 Metev_2021 Metev_2022 Metev_2023
MZH: Mzhil_0753 Mzhil_0754 Mzhil_1717 Mzhil_1718 Mzhil_1719 Mzhil_1720 Mzhil_1721 Mzhil_1722 Mzhil_1723 Mzhil_1724
MPY: Mpsy_0233 Mpsy_2182 Mpsy_2183 Mpsy_2184 Mpsy_2185 Mpsy_2186 Mpsy_2187 Mpsy_2188 Mpsy_2189
MZI: HWN40_11260 HWN40_11265(mtrD) HWN40_11270 HWN40_11275 HWN40_11280 HWN40_11285 HWN40_11290(mtrG) HWN40_11295(mtrH)
MMAV: RE476_11925(mtrH) RE476_11930(mtrG) RE476_11935 RE476_11940(mtrA) RE476_11945 RE476_11950(mtrC) RE476_11955(mtrD) RE476_11960(mtrE)
MSEB: RE474_08825(mtrH) RE474_08830(mtrG) RE474_08835 RE474_08840(mtrA) RE474_08845 RE474_08850(mtrC) RE474_08855(mtrD) RE474_08860(mtrE)
MHZ: Metho_0912 Metho_2089 Metho_2090 Metho_2091 Metho_2092 Metho_2093 Metho_2094 Metho_2095 Metho_2096
MEHF: MmiHf6_12630(mtgA) MmiHf6_12640 MmiHf6_12650 MmiHf6_12660 MmiHf6_12670 MmiHf6_12680 MmiHf6_12690 MmiHf6_12700
MEES: MmiEs2_15070(mtgA) MmiEs2_15080 MmiEs2_15090 MmiEs2_15100 MmiEs2_15110 MmiEs2_15120 MmiEs2_15130 MmiEs2_15140
MTP: Mthe_1378 Mthe_1379 Mthe_1380 Mthe_1381 Mthe_1382 Mthe_1383 Mthe_1384 Mthe_1385 Mthe_1654
MCJ: MCON_1068(mtrH) MCON_1069(mtrG) MCON_1070(mtrF) MCON_1071(mtrA) MCON_1072(mtrB) MCON_1073(mtrC) MCON_1074(mtrD) MCON_1075(mtrE) MCON_2872 MCON_2873
MHI: Mhar_1269 Mhar_1473 Mhar_2090 Mhar_2091 Mhar_2092 Mhar_2093 Mhar_2094 Mhar_2095 Mhar_2096 Mhar_2097
MHU: Mhun_2168 Mhun_2169 Mhun_2170 Mhun_2171 Mhun_2172 Mhun_2173 Mhun_2174 Mhun_2175
MRTJ: KHC33_15200(mtrE) KHC33_15205(mtrD) KHC33_15210(mtrC) KHC33_15215(mtrB) KHC33_15220(mtrA) KHC33_15225 KHC33_15230(mtrA) KHC33_15235
MLA: Mlab_1553 Mlab_1554 Mlab_1555 Mlab_1556 Mlab_1557 Mlab_1558 Mlab_1559 Mlab_1560
MEM: Memar_0605 Memar_0606 Memar_0607 Memar_0608 Memar_0609 Memar_0610 Memar_0611 Memar_0612
MBG: BN140_1739(mtrE) BN140_1740(mtrD) BN140_1741(mtrC) BN140_1742(mtrB) BN140_1743(mtrA1) BN140_1744(mtrF) BN140_1745(mtrA2) BN140_1746(mtrH)
MEMA: MMAB1_2236(mtrE) MMAB1_2237(mtrD) MMAB1_2238(mtrC) MMAB1_2239 MMAB1_2241 MMAB1_2242(mtrF) MMAB1_2243(mtrA) MMAB1_2244(mtrH)
MCHK: MchiMG62_07340(mtrH) MchiMG62_07350(mtrA_1) MchiMG62_07360 MchiMG62_07370(mtrA_2) MchiMG62_07380 MchiMG62_07390(mtrC) MchiMG62_07400(mtrD) MchiMG62_07410
MSUM: OH143_09745(mtrH) OH143_09750(mtrA) OH143_09755 OH143_09760(mtrA) OH143_09765(mtrB) OH143_09770(mtrC) OH143_09775(mtrD) OH143_09780(mtrE)
MRC: R6Y96_02655(mtrE) R6Y96_02660(mtrD) R6Y96_02665(mtrC) R6Y96_02670(mtrB) R6Y96_02675(mtrA) R6Y96_02680 R6Y96_02685(mtrA) R6Y96_02690(mtrH)
MPI: Mpet_2407 Mpet_2408 Mpet_2409 Mpet_2410 Mpet_2411 Mpet_2412 Mpet_2413 Mpet_2414
MEND: L6E24_09510(mtrE) L6E24_09515(mtrD) L6E24_09520(mtrC) L6E24_09525(mtrB) L6E24_09530(mtrA) L6E24_09540(mtrA) L6E24_09545(mtrH)
MEFW: F1737_00905 F1737_00910 F1737_00915 F1737_00920(mtrB) F1737_00925 F1737_00930 F1737_00935(mtrA) F1737_00940
MAQE: RJ40_06100 RJ40_06105 RJ40_06110 RJ40_06115(mtrB) RJ40_06120 RJ40_06125 RJ40_06130(mtrA) RJ40_06135
MFK: E2N92_06230 E2N92_06235 E2N92_06240 E2N92_06245(mtrB) E2N92_06250 E2N92_06255 E2N92_06260(mtrA) E2N92_06265
MOU: OU421_03470(mtrH) OU421_03475(mtrA) OU421_03480 OU421_03485(mtrA) OU421_03490(mtrB) OU421_03495(mtrC) OU421_03500(mtrD) OU421_03505(mtrE)
MESB: L1S32_07070(mtrH) L1S32_07075(mtrA) L1S32_07080 L1S32_07085(mtrA) L1S32_07090(mtrB) L1S32_07095(mtrC) L1S32_07100(mtrD) L1S32_07105(mtrE)
MANQ: L1994_01325(mtrE) L1994_01330(mtrD) L1994_01335(mtrC) L1994_01340(mtrB) L1994_01345(mtrA) L1994_01350 L1994_01355(mtrA) L1994_01360(mtrH)
MBN: Mboo_0566 Mboo_0567 Mboo_0568 Mboo_0569 Mboo_0570 Mboo_0571 Mboo_0572 Mboo_0573
MFO: Metfor_2614 Metfor_2615 Metfor_2616 Metfor_2617 Metfor_2618 Metfor_2619 Metfor_2620 Metfor_2621
MESK: METHP_00392 METHP_00393 METHP_00396 METHP_00398 METHP_00399
MPL: Mpal_2310 Mpal_2311 Mpal_2312 Mpal_2313 Mpal_2314 Mpal_2315 Mpal_2316 Mpal_2317 Mpal_2572
MPD: MCP_0539(mtrE) MCP_0540(mtrD) MCP_0541(mtrC) MCP_0542(mtrB) MCP_0543(mtrA-1) MCP_0544(mtrF) MCP_0545(mtrG) MCP_0546(mtrH) MCP_0678(mtrA-2)
MEZ: Mtc_0936(mtrE) Mtc_0937(mtrD) Mtc_0938(mtrC) Mtc_0939(mtrB) Mtc_0940(mtrA-1) Mtc_0941(mtrF) Mtc_0942(mtrG) Mtc_0943(mtrH) Mtc_0962(mtrA-2)
RCI: RCIX2064(mtrE) RCIX2065(mtrD) RCIX2066(mtrC) RCIX2067(mtrB) RCIX2068(mtrA-1) RCIX2069(mtrA-2) RCIX2070(mtrG) RCIX2071(mtrH)
MJK: N2V74_07235(mtrH) N2V74_07240(mtrG) N2V74_07245(mtrF) N2V74_07250(mtrA) N2V74_07255(mtrB) N2V74_07260(mtrC) N2V74_07265(mtrD) N2V74_07270(mtrE)
HALH: HTSR_1745(mtrH)
HHSR: HSR6_1811(mtrH)
HDF: AArcSl_0464(mtrH)
MELU: MTLP_08710 MTLP_08720(mtrD) MTLP_08730(mtrC) MTLP_08740 MTLP_08750 MTLP_08770 MTLP_08780
SMR: Smar_0413
SHC: Shell_0390
IAG: Igag_0398
THG: TCELL_0694
KCR: Kcr_0196
NMR: Nmar_1747
NIR: NSED_09300
NKR: NKOR_09280
NID: NPIRD3C_0197
NIN: NADRNF5_0123
NIW: Nisw_05290
NCL: C5F47_09020
NOX: C5F49_08915
NUE: C5F50_12355
NIP: NsoK4_09640
NZT: NZOSNM25_000061
NCT: NMSP_1666(mtrA1)
NIC: DSQ20_09905
NGA: Ngar_c18160
NVN: NVIE_004250
NEV: NTE_01720
TAA: NMY3_01886
NFN: NFRAN_2697
NCV: NCAV_0248
NDV: NDEV_2077
CSY: CENSYa_1432
TAH: SU86_006000
NIU: DSQ19_00180
NCK: QVH35_03540
CCAI: NAS2_0151
BARC: AOA65_1010(mtrH_2) AOA65_2047(mtrH_3)
LOKI: Lokiarch_10270(mtrH_1) Lokiarch_42890(mtrH_2) Lokiarch_51490(mtrH_3)
 » show all
Reference
1  [PMID:3085670]
  Authors
Sauer FD.
  Title
Tetrahydromethanopterin methyltransferase, a component of the methane synthesizing complex of Methanobacterium thermoautotrophicum.
  Journal
Biochem Biophys Res Commun 136:542-7 (1986)
DOI:10.1016/0006-291X(86)90474-2
Reference
2  [PMID:8477726]
  Authors
Gartner P, Ecker A, Fischer R, Linder D, Fuchs G, Thauer RK
  Title
Purification and properties of N5-methyltetrahydromethanopterin:coenzyme M methyltransferase from Methanobacterium thermoautotrophicum.
  Journal
Eur J Biochem 213:537-45 (1993)
DOI:10.1111/j.1432-1033.1993.tb17792.x
  Sequence
[mmg:MTBMA_c15400 MTBMA_c15430 MTBMA_c15450 MTBMA_c15460 MTBMA_c15470]
Reference
3  [PMID:7813469]
  Authors
Weiss DS, Gartner P, Thauer RK
  Title
The energetics and sodium-ion dependence of N5-methyltetrahydromethanopterin:coenzyme M methyltransferase studied with cob(I)alamin as methyl acceptor and methylcob(III)alamin as methyl donor.
  Journal
Eur J Biochem 226:799-809 (1994)
DOI:10.1111/j.1432-1033.1994.00799.x
Reference
4  [PMID:7737157]
  Authors
Harms U, Weiss DS, Gartner P, Linder D, Thauer RK
  Title
The energy conserving N5-methyltetrahydromethanopterin:coenzyme M methyltransferase complex from Methanobacterium thermoautotrophicum is composed of eight different subunits.
  Journal
Eur J Biochem 228:640-8 (1995)
DOI:10.1111/j.1432-1033.1995.0640m.x
  Sequence
[mmg:MTBMA_c15470 MTBMA_c15420 MTBMA_c15410 MTBMA_c15400]
Reference
5  [PMID:11248186]
  Authors
Gottschalk G, Thauer RK
  Title
The Na(+)-translocating methyltransferase complex from methanogenic archaea.
  Journal
Biochim Biophys Acta 1505:28-36 (2001)
DOI:10.1016/S0005-2728(00)00274-7
Reference
6  [PMID:22636775]
  Authors
Vepachedu VR, Ferry JG
  Title
Role of the fused corrinoid/methyl transfer protein CmtA during CO-dependent growth of Methanosarcina acetivorans.
  Journal
J Bacteriol 194:4161-8 (2012)
DOI:10.1128/JB.00593-12
  Sequence
[mac:MA_4384]
Other DBs
ExplorEnz - The Enzyme Database: 7.2.1.4
IUBMB Enzyme Nomenclature: 7.2.1.4
ExPASy - ENZYME nomenclature database: 7.2.1.4
BRENDA, the Enzyme Database: 7.2.1.4
CAS: 103406-60-6

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