KEGG   ENZYME: 7.2.2.15
Entry
EC 7.2.2.15                 Enzyme                                 
Name
P-type Ag+ transporter;
Ag+-exporting ATPase
Class
Translocases;
Catalysing the translocation of inorganic cations;
Linked to the hydrolysis of a nucleoside triphosphate
Sysname
ATP phosphohydrolase (P-type, Ag+-exporting)
Reaction(IUBMB)
ATP + H2O + Ag+[side 1] = ADP + phosphate + Ag+[side 2]
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001];
Ag+[side 1]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
Ag+[side 2]
Comment
A P-type ATPase that exports Ag+ ions from some bacteria, archaea as well as from some animal tissues. The proteins also transport Cu+ ions (cf. EC 7.2.2.8, P-type Cu+ transporter).
History
EC 7.2.2.15 created 2000 as EC 3.6.3.53, transferred 2018 to EC 7.2.2.15
Orthology
K23254  P-type Ag+ transporter
Genes
ESLO3K_01545
ESOO3O_24100
ESMO3M_01590
ECKEC55989_3910(silP)
ELHETEC_0224
ECVAPECO1_O1R116(silP)
ECLEcolC_3420
ELPP12B_c3605(silP)
SENHCFSAN002069_14200
SEECCFSAN002050_22065
SENCSEET0819_01575
ENCECL_04885 ECL_A028
ECLEECNIH2_22210
ECLNECNIH4_01590
ECLIECNIH5_22410
ECLXLI66_21485
ECLYLI62_23505
ECLZLI64_20590
EHMAB284_03340
ECLCECR091_23065
EKBBFV64_23730
ECLSLI67_022975
ECHGFY206_23090(silP)
ENXNI40_012330
ENDA4308_05725
ENZG0034_21635(silP)
ENSHWQ15_06820(silP)
ESAESA_04245
CSJCSK29544_3p0034
CSIP262_p2070
CMJAFK66_020390
CTUCtu_3p00600(silP)
KPNKPN_pKPN3p05945(silP)
KPUKP1_p145(silP)
KPHKPNIH24_27735
KPZKPNIH27_27870
KPVKPNIH29_27290
KPYKPNIH31_26300
KPGKPNIH32_28730
KPCKPNIH10_27070
KPOKPN2242_25446
KPJN559_5295
KPAKPNJ1_05574
KPXPMK1_a00110(silP)
KPNEKU54_00340
KPNULI86_27195
KOMHR38_28340
KOKKONIH1_29550
KOCAB185_02350
KQUAVR78_26350
KQVB8P98_27970
KLWDA718_29665(silP)
KGRJJJ10_28570(silP)
RTGNCTC13098_04593(actP_1)
CFDCFNIH1_01975
CWECO701_01880
CSEDJY391_01240(silP)
CAMAF384_23500
CAFAL524_01700
CIRC2U53_08300
CIEAN232_02045
CTELGBC03_26455(silP)
CARSE1B03_00520(silP)
LEIC2U54_25110
LEHC3F35_24465
LEEDVA44_25385
METYMRY16398_p10100 MRY16398_p11080
KINAB182_01365 AB182_01725
PDZHHA33_25710(silP)
PVJLMA04_09045(silP)
EBCC2U52_01690
YEEYE5303_30421
YCAF0T03_02185
YKIHRD70_06600
PANPPSNIH2_23070
SPCSputcn32_0264
SHNShewana3_4302
ASAAKXJ75_06325(silP)
DBKDGMP_03980
NANNO0S08_24185
AALMLUX29_12290
OLEK0B96_13145(cadA) K0B96_16280
SAHNJRG66_09620
 » show all
Reference
1  [PMID:9930866]
  Authors
Gupta A, Matsui K, Lo JF, Silver S
  Title
Molecular basis for resistance to silver cations in Salmonella.
  Journal
Nat Med 5:183-8 (1999)
DOI:10.1038/5545
  Sequence
Reference
2  [PMID:10448119]
  Authors
Bury NR, Grosell M, Grover AK, Wood CM.
  Title
ATP-dependent silver transport across the basolateral membrane of rainbow trout gills.
  Journal
Toxicol Appl Pharmacol 159:1-8 (1999)
DOI:10.1006/taap.1999.8706
Other DBs
ExplorEnz - The Enzyme Database: 7.2.2.15
IUBMB Enzyme Nomenclature: 7.2.2.15
ExPASy - ENZYME nomenclature database: 7.2.2.15
BRENDA, the Enzyme Database: 7.2.2.15

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