KEGG   ENZYME: 7.2.2.17Help
Entry
EC 7.2.2.17                 Enzyme                                 

Name
ABC-type ferric enterobactin transporter;
ferric enterobactin transporting ATPase;
ferric enterobactin ABC transporter;
fepBCDG (gene names)
Class
Translocases;
Catalysing the translocation of inorganic cations;
Linked to the hydrolysis of a nucleoside triphosphate
BRITE hierarchy
Sysname
ATP phosphohydrolase (ABC-type, iron(III) enterobactin-importing)
Reaction(IUBMB)
ATP + H2O + Fe3+-enterobactin complex-[enterobactin-binding protein][side 1] = ADP + phosphate + Fe3+-enterobactin complex[side 2] + [enterobactin-binding protein][side 1]
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001];
Fe3+-enterobactin complex-[enterobactin-binding protein][side 1]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
Fe3+-enterobactin complex[side 2];
[enterobactin-binding protein][side 1]
Comment
An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the high affinity uptake of Fe3+-enterobactin complexes.
History
EC 7.2.2.17 created 2000 as EC 3.6.3.34, part transferred 2018 to EC 7.2.2.17
Orthology
K23188  ferric enterobactin transport system ATP-binding protein
Genes
ECO: b0588(fepC)
ECJ: JW0580(fepC)
ECD: ECDH10B_0548(fepC) ECDH10B_0656(fepC)
EBW: BWG_0461(fepC)
ECOK: ECMDS42_0449(fepC)
ECE: Z0729(fepC)
ECS: ECs0627
ECF: ECH74115_0672(fepC)
ETW: ECSP_0642(fepC)
ELX: CDCO157_0612
EOJ: ECO26_0663(fepC)
EOI: ECO111_0618(fepC)
EOH: ECO103_0596(fepC)
ECOO: ECRM13514_0610(fepC)
ECOH: ECRM13516_0554(fepC)
ECG: E2348C_0490(fepC)
EOK: G2583_0751(fepC)
ESO: O3O_06645
ESM: O3M_18630
ESL: O3K_18650
ECW: EcE24377A_0607(fepC)
ELH: ETEC_0618
EUN: UMNK88_620(fepC)
ECC: c0675(fepC)
ECP: ECP_0620
ECI: UTI89_C0590(fepC)
ECV: APECO1_1461(fepC)
ECX: EcHS_A0639(fepC)
ECM: EcSMS35_0607(fepC)
ECY: ECSE_0655
ECR: ECIAI1_0572(fepC)
ECQ: ECED1_0585(fepC)
ECK: EC55989_0580(fepC)
ECT: ECIAI39_0565(fepC)
EOC: CE10_0588(fepC)
EUM: ECUMN_0682(fepC)
ECZ: ECS88_0627(fepC)
ELO: EC042_0626(fepC)
ESE: ECSF_0529
EBR: ECB_00555(fepC)
EBD: ECBD_3067
EKF: KO11_20725(fepC)
EAB: ECABU_c06380(fepC)
EDJ: ECDH1ME8569_0558(fepC)
EIH: ECOK1_0599(fepC)
ENA: ECNA114_0531(fepC)
ELW: ECW_m0643(fepC)
ELL: WFL_03195(fepC)
ELC: i14_0649(fepC)
ELD: i02_0649(fepC)
ELP: P12B_c0573(fepC)
EBL: ECD_00555(fepC)
EBE: B21_00544(fepC)
ELF: LF82_0642(fepC)
ECOI: ECOPMV1_00606(yusV_1)
ECOJ: P423_02885
ECOS: EC958_0708(fepC)
EFE: EFER_2506(fepC)
STY: STY0634(fepC)
STT: t2278(fepC)
STM: STM0590(fepC)
SEO: STM14_0688(fepC)
SEY: SL1344_0578(fepC)
SEJ: STMUK_0595(fepC)
SEB: STM474_0610(fepC)
SEF: UMN798_0639(fepC)
SENR: STMDT2_05811(fepC)
SEND: DT104_06181(fepC)
SENI: CY43_03235
SPT: SPA2144(fepC)
SEK: SSPA1994
SEI: SPC_0602(fepC)
SEC: SCH_0621(fepC)
SHB: SU5_01280
SENS: Q786_02880
SED: SeD_A0686
SEG: SG0594(fepC)
SEL: SPUL_2376(fepC)
SEGA: SPUCDC_2362(fepC)
SET: SEN0559(fepC)
SENA: AU38_02860
SENO: AU37_02855
SENV: AU39_02860
SENQ: AU40_03150
SENL: IY59_02915
SEEP: I137_10835
SENB: BN855_5820(fepC)
SENE: IA1_03095
SBG: SBG_0498(fepC)
SBZ: A464_563
SFL: SF0502(fepC)
SFX: S0508(fepC)
SFV: SFV_0536(fepC)
SFE: SFxv_0555(fepC)
SFN: SFy_0653
SFS: SFyv_0692
SFT: NCTC1_00523(fepC)
SSN: SSON_0539(fepC)
SBO: SBO_0449(fepC)
SBC: SbBS512_E0489(fepC)
SDY: SDY_0519(fepC)
ENC: ECL_03113
ECLX: LI66_05645
ECLY: LI62_06555
ECLZ: LI64_06150
EEC: EcWSU1_01163(fepC)
ENF: AKI40_3698(fepC)
EBG: FAI37_00745(fepC)
ESA: ESA_00791
CSK: ES15_1060(fepC)
CTU: CTU_30520(fepC)
KPN: KPN_00606(fepC)
KPU: KP1_1551(fepC)
KPP: A79E_3634
KPT: VK055_1930(fepC)
KPE: KPK_3972(fepC)
KPJ: N559_3720
KPX: PMK1_02937(yusV_2)
KPNU: LI86_19075
KPNK: BN49_1662(fepC)
KVA: Kvar_3762
KOX: KOX_13910
KOE: A225_1601
EAE: EAE_13620
EAR: CCG31247
CKO: CKO_02573
CRO: ROD_05971(fepC)
CAMA: F384_02595
GQU: AWC35_18940(fecE)
EBT: EBL_c13860(fepC)
RTG: NCTC13098_05439(yusV_3)
KIE: NCTC12125_02378(yusV_2)
AHN: NCTC12129_03606(fepC)
IZH: FEM41_12915(fepC)
EBF: D782_3249
YEN: YE3621(fepC)
YEL: LC20_00743(fecE)
YEW: CH47_4178
YET: CH48_2302
YEE: YE5303_03361(fepC)
YAL: AT01_1916
YFR: AW19_2619
YIN: CH53_2396
YKR: CH54_3169
YRO: CH64_2001
YRU: BD65_1346
YRB: UGYR_07455(fecE)
YAK: ACZ76_06025(fecE)
YMA: DA391_03030(fecE)
SPE: Spro_3426
SRL: SOD_c33470(fepC)
SPLY: Q5A_018135(yusV)
SMAF: D781_3212
SMW: SMWW4_v1c35430(fepC)
SMAR: SM39_3041(fepC)
SMAC: SMDB11_2826(fepC)
SERF: L085_10970
SFW: WN53_26500(fecE)
SFG: AV650_22585(fecE)
SERA: Ser39006_010860(fecE)
SERQ: CWC46_10855(fecE)
SERM: CLM71_16970(fecE)
SFO: Z042_04185(fecE)
RAA: Q7S_02740
PPAR: A8F97_00010(fecE)
PEC: W5S_3873
PWS: A7983_03705(fecE)
DDD: Dda3937_03036(cbuC)
DSO: A4U42_02215(fecE)
CED: LH89_19435(fecE)
DFN: CVE23_15090(fecE)
DDQ: DDI_2785
DAQ: DAQ1742_01265(cbuC)
BGJ: AWC36_23015(fecE)
LBQ: CKQ53_17075(fecE)
EGE: EM595_0489(fepC)
EPE: CI789_04425(fecE)
PVA: Pvag_3662(fepC)
PAGG: AL522_06440(fecE)
KLN: LH22_19805(fecE)
PAGC: BEE12_09220(fecE)
TCI: A7K98_01190(fecE)
TPTY: NCTC11468_00308(yusV_1)
PAY: PAU_00891(phuC)
PTT: VY86_02575(fecE)
PVG: CRN77_04105(fecE)
PHAU: PH4a_07050(fecE)
XBO: XBJ1_1442(fepC)
XBV: XBW1_1499(fepC)
VCH: VC0779
VCF: IR04_09295(fecE)
VCS: MS6_0591
VCE: Vch1786_I0285(viuC)
VCQ: EN18_07285(fecE)
VCI: O3Y_03630
VCO: VC0395_A0308(viuC)
VCR: VC395_0796(viuC)
VCM: VCM66_0737(viuC)
VAG: N646_0833
VSP: VS_1126(viuC)
VNI: VIBNI_B0630(fepC)
VFL: AL536_11495(fecE)
VGA: BSQ33_15345(fecE)
VTA: B0473(fepC)
POR: APT59_14290(fecE)
PPSL: BJP27_05270(fecE)
PSPO: PSPO_a3283
HCH: HCH_03795
CVI: CV_2234(fepC)
CVC: BKX93_01155(fecE)
CHRO: CXB49_11675(fecE)
CHRI: DK842_18540(fecE)
CHRB: DK843_01225(fecE)
AXX: ERS451415_00256(yusV_1)
ODI: ODI_R4251
JAB: VN23_17085(fecE)
RCP: RCAP_rcc01441(fepC2)
RSU: NHU_04510
RHM: B5V46_18960(fecE)
 » show all
Taxonomy
Reference
1  [PMID:1787794]
  Authors
Chenault SS, Earhart CF
  Title
Organization of genes encoding membrane proteins of the Escherichia coli ferrienterobactin permease.
  Journal
Mol Microbiol 5:1405-13 (1991)
DOI:10.1111/j.1365-2958.1991.tb00787.x
  Sequence
[eco:b0590]
Reference
2  [PMID:1838574]
  Authors
Shea CM, McIntosh MA.
  Title
Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding protein-dependent systems in Escherichia coli.
  Journal
Mol Microbiol 5:1415-28 (1991)
DOI:10.1111/j.1365-2958.1991.tb00788.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 7.2.2.17
IUBMB Enzyme Nomenclature: 7.2.2.17
ExPASy - ENZYME nomenclature database: 7.2.2.17
BRENDA, the Enzyme Database: 7.2.2.17

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