Entry
Name
ABC-type Na+ transporter;
natAB (gene names)
Class
Translocases;
Catalysing the translocation of inorganic cations;
Linked to the hydrolysis of a nucleoside triphosphate
BRITE hierarchy
Sysname
ATP phosphohydrolase (ABC-type, Na+-exporting)
Reaction(IUBMB)
ATP + H2O + Na+[side 1] = ADP + phosphate + Na+[side 2]
Substrate
Product
Comment
ABC-type (ATP-binding cassette-type) transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. This bacterial enzyme, characterized from Bacillus subtilis, exports Na+ ions out of the cell. cf. EC
7.2.2.1 , Na+-transporting two-sector ATPase and EC
7.2.2.3 , P-type Na+ transporter.
History
EC 7.2.2.4 created 2018
Orthology
K09697 sodium transport system ATP-binding protein
Genes
XPH : XppCFBP6546_14210(XppCFBP6546P_14210)
XHY : FZ025_10880 FZ025_17195
XHD : LMG31886_41720(natA)
LLZ : LYB30171_00035(natA)
SCAA : TUM17387_01000(natA)
THAT : H3N35_05400 H3N35_16765
TACT : SG35_005525 SG35_017705
TVD : SG34_005940 SG34_011545
PBW : D172_008455 D172_014700
PRR : AT705_03055 AT705_04390
PLZ : S4054249_07120 S4054249_11455
PPIS : B1L02_06670 B1L02_08855
PSEN : PNC201_08245(ybhF3) PNC201_10085(yxlF3)
PVB : J5X90_14715 J5X90_16250
PSAZ : PA25_14880(natA) PA25_30480
PFLI : CTT31_09445 CTT31_10425
PMAZ : R5H13_09975 R5H13_10980
MICC : AUP74_01352(ybhF_1)
WEZ : IC757_13115 IC757_16230
GAI : IMCC3135_23080(natA_3)
MASS : CR152_07035 CR152_07060
MTIM : DIR46_06690 DIR46_09835
MANC : IV454_13100 IV454_13125
URU : DSM104443_01959(natA)
UPL : DSM104440_01804(natA)
PPAK : JY651_02140 JY651_45905
SUR : STAUR_1024(natA) STAUR_7307
AGE : AA314_01942 AA314_09558
PAUU : E8A73_013865 E8A73_023850
OBG : Verru16b_00937(ybhF_1)
PIR : VN12_01280(ybhF_1) VN12_03175(ybhF_3)
RUL : UC8_31820(ybhF_3) UC8_47060(ybhF_5)
RML : FF011L_30800(ybhF_3) FF011L_44070(ecsA_1)
MFF : MFFC18_31870(ybhF_5) MFFC18_33260(drrA_2)
ROL : CA51_20170(ybhF_4) CA51_30210(drrA_1)
RUV : EC9_17600(ybhF_6) EC9_23300(drrA_1)
RCF : Poly24_19700(ybhF_5) Poly24_30880(ecsA_2)
AHEL : Q31a_33340(ybhF_4) Q31a_34180(ybhF_5)
LCRE : Pla8534_37890(ybhF_3) Pla8534_40060(ybhF_4)
AAGG : ETAA8_42970(drrA_2) ETAA8_63340(ybhF_7)
RLC : K227x_42340(ybhF_5) K227x_45410(ybhF_7)
SMAM : Mal15_09820(ybhF_2) Mal15_51120(ecsA_4)
SNEP : Enr13x_11300(ecsA_2) Enr13x_63370(ybhF_5)
AMUC : Pan181_26790(drrA_3)
PND : Pla175_20850(drrA_1)
AMOB : HG15A2_28390(ybhF_3)
BMEI : Spa11_27980(ybhF_2)
PEH : Spb1_16480(ybhF_2) Spb1_38790(ybhF_4)
PBS : Plabr_0554 Plabr_1301
PLS : VT03_02120(ybhF_1) VT03_02900(ybhF_2)
FMR : Fuma_02068(ybhF_5) Fuma_04071(ybhF_8)
GMR : GmarT_04710(ybhF_1) GmarT_40000(ybhF_6)
GIM : F1728_11795 F1728_26140
GPN : Pan110_05310(ybhF_2) Pan110_38810(ybhF_6)
GFM : Enr17x_06420(ybhF_2) Enr17x_41070(ybhF_7)
GAZ : Pan241w_05340(ybhF_1) Pan241w_40390(ybhF_5)
GAW : V144x_20890(ybhF_3) V144x_52640(ybhF_8)
GAX : Pan161_30030(ybhF_5) Pan161_40840(ybhF_7)
SDYN : Mal52_07020(ybhF_1) Mal52_11530(ybhF_2)
PLON : Pla110_04260(ybhF_1) Pla110_32210(ybhF_5)
ACAF : CA12_23810(ybhF_2) CA12_36090(ybhF_4)
SVP : Pan189_21760(ybhF_2) Pan189_39630(ybhF_5)
TPOL : Mal48_40490(ybhF_5)
CHYA : V22_18730(drrA_1) V22_38110(ybhF_4)
CCOS : Pan44_04580(ybhF_1) Pan44_31170(ybhF_4)
PVAR : SH412_000015 SH412_000814
CCOP : Mal65_22880(ybhF_2) Mal65_23990(ybhF_3)
PBOR : BSF38_00882(natA_2)
PBAP : Pla133_26970(ybhF_2)
BSO : BSNT_06592 BSNT_06593
BACL : BS34A_03300(natA_1)
MEBZ : LPC09_02375 LPC09_26510
BLEN : NCTC4824_00469(natA)
BLR : BRLA_c005380(ybhF_2)
CPAE : CPAST_c08480(natA1)
HHW : NCTC503_00250(ybhF_1)
CSCI : HDCHBGLK_00264(natA_2)
CHYL : CE91St63_26670(natA)
ACEL : acsn021_02030(natA)
ACHT : bsdcttw_34680(natA)
CBAR : PATL70BA_1648(natA)
PHX : KGNDJEFE_01735(natA)
TPET : TPHSE_15430(natA_2)
TEX : Teth514_0340 Teth514_0363
THEZ : OEI98_000442 OEI98_000449
CDIA : CaldiYA01_01090(natA)
AHK : NCTC10172_00227(drrA_1)
AAXA : NCTC10138_01153(bcrA_4)
» show all
Taxonomy
Reference
Authors
Cheng J, Guffanti AA, Krulwich TA
Title
A two-gene ABC-type transport system that extrudes Na+ in Bacillus subtilis is induced by ethanol or protonophore.
Journal
Sequence
Reference
Authors
Ogura M, Tsukahara K, Hayashi K, Tanaka T
Title
The Bacillus subtilis NatK-NatR two-component system regulates expression of the natAB operon encoding an ABC transporter for sodium ion extrusion.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 7.2.2.4
ExPASy - ENZYME nomenclature database: 7.2.2.4
BRENDA, the Enzyme Database: 7.2.2.4