KEGG   ENZYME: 7.4.2.7Help
Entry
EC 7.4.2.7                  Enzyme                                 

Name
ABC-type alpha-factor-pheromone transporter;
alpha-factor-transporting ATPase;
alpha-factor-pheromone transporting ATPase
Class
Translocases;
Catalysing the translocation of amino acids and peptides;
Linked to the hydrolysis of a nucleoside triphosphate
BRITE hierarchy
Sysname
ATP phosphohydrolase (ABC-type, alpha-factor-exporting)
Reaction(IUBMB)
ATP + H2O + alpha-factor[side 1] = ADP + phosphate + alpha-factor[side 2]
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001];
alpha-factor[side 1]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
alpha-factor[side 2]
Comment
An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. Does not undergo phosphorylation during the transport process. A yeast enzyme that exports the alpha-factor sex pheromone.
History
EC 7.4.2.7 created 2000 as EC 3.6.3.48, transferred 2018 to EC 7.4.2.7
Reference
1  [PMID:8095825]
  Authors
Michaelis S.
  Title
STE6, the yeast a-factor transporter.
  Journal
Semin Cell Biol 4:17-27 (1993)
  Sequence
[sce:YKL209C]
Reference
2  [PMID:9889977]
  Authors
Saier MH Jr.
  Title
Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya.
  Journal
Adv Microb Physiol 40:81-136 (1998)
Other DBs
ExplorEnz - The Enzyme Database: 7.4.2.7
IUBMB Enzyme Nomenclature: 7.4.2.7
ExPASy - ENZYME nomenclature database: 7.4.2.7
BRENDA, the Enzyme Database: 7.4.2.7

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