| Entry |
|
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| Name |
ABC-type capsular-polysaccharide transporter;
capsular-polysaccharide-transporting ATPase
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| Class |
Translocases;
Catalysing the translocation of other compounds;
Linked to the hydrolysis of a nucleoside triphosphate
 |
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| Sysname |
ATP phosphohydrolase (ABC-type, capsular-polysaccharide-exporting)
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| Reaction(IUBMB) |
ATP + H2O + capsular polysaccharide-[capsular polysaccharide-binding protein][side 1] = ADP + phosphate + capsular polysaccharide[side 2] + [capsular polysaccharide-binding protein][side 1]
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| Substrate |
ATP [CPD: C00002];
H2O [CPD: C00001];
capsular polysaccharide-[capsular polysaccharide-binding protein][side 1]
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| Product |
ADP [CPD: C00008];
phosphate [CPD: C00009];
capsular polysaccharide[side 2];
[capsular polysaccharide-binding protein][side 1]
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| Comment |
ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. An enzyme that exports capsular polysaccharide in Gram-negative bacteria.
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| History |
EC 7.6.2.12 created 2000 as EC 3.6.3.38, transferred 2018 to EC 7.6.2.12
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| Orthology |
| K09689 | capsular polysaccharide transport system ATP-binding protein |
| K22923 | Vi polysaccharide transport system ATP-binding protein |
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| Genes |
» show all
 |
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| Reference |
|
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| Authors |
Fath MJ, Kolter R. |
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| Title |
ABC transporters: bacterial exporters. |
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| Journal |
Microbiol Rev 57:995-1017 (1993) |
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| Reference |
|
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| Authors |
Paulsen IT, Beness AM, Saier MH Jr. |
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| Title |
Computer-based analyses of the protein constituents of transport systems catalysing export of complex carbohydrates in bacteria. |
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| Journal |
|
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| Reference |
|
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| Authors |
Pigeon RP, Silver RP. |
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| Title |
Analysis of the G93E mutant allele of KpsM, the membrane component of an ABC transporter involved in polysialic acid translocation in Escherichia coli K1. |
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| Journal |
|
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| Reference |
|
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| Authors |
Saier MH Jr. |
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| Title |
Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya. |
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| Journal |
Adv Microb Physiol 40:81-136 (1998) |
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| Reference |
5 |
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| Authors |
Griffiths, J.K. and Sansom, C.E. |
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| Title |
The Transporter Factsbook, Academic Press, San Diego, 1998. |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 7.6.2.12 |
| ExPASy - ENZYME nomenclature database: | 7.6.2.12 |
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