EC 220.127.116.11 Enzyme
ABC-type autoinducer-2 transporter;
autoinducer-2 transporting ATPase;
autoinducer-2 ABC transporter;
LsrACDB (gene names)
Catalysing the translocation of other compounds;
Linked to the hydrolysis of a nucleoside triphosphate
ATP phosphohydrolase (ABC-type, AI-2 importing)
ATP + H2O + (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran-[AI-2-binding protein][side 1] = ADP + phosphate + (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran[side 2] + [AI-2-binding protein][side 1]
(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran-[AI-2-binding protein][side 1]
[AI-2-binding protein][side 1]
ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the uptake of the signalling molecule (2R,4S)-2-methyl-2,3,3,4-tetrahydoxytetrahydrofuran (also known as autoinducer-2).
EC 18.104.22.168 created 2019
Taga ME, Semmelhack JL, Bassler BL
The LuxS-dependent autoinducer AI-2 controls the expression of an ABC transporter that functions in AI-2 uptake in Salmonella typhimurium.
Mol Microbiol 42:777-93 (2001)
Xavier KB, Bassler BL
Regulation of uptake and processing of the quorum-sensing autoinducer AI-2 in Escherichia coli.
J Bacteriol 187:238-48 (2005)
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