EC 188.8.131.52 Enzyme
ABC-type thiamine transporter;
thiamin transporting ATPase;
thiamine ABC transporter;
thiamin ABC transporter;
thiamine transporting ATPase;
thiBPQ (gene names)
Catalysing the translocation of other compounds;
Linked to the hydrolysis of a nucleoside triphosphate
ATP phosphohydrolase (ABC-type, thiamine-importing)
ATP + H2O + thiamine-[thiamine-binding protein][side 1] = ADP + phosphate + thiamine[side 2] + [thiamine-binding protein][side 1]
thiamine-[thiamine-binding protein][side 1]
[thiamine-binding protein][side 1]
ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme, characterized from the bacterium Salmonella typhimurium, is a heterodimeric complex that interacts with an extracytoplasmic substrate binding protein and functions to import thiamine, thiamine monophosphate and thiamine diphosphate.
EC 184.108.40.206 created 2019
Webb E, Claas K, Downs D
thiBPQ encodes an ABC transporter required for transport of thiamine and thiamine pyrophosphate in Salmonella typhimurium.
J Biol Chem 273:8946-50 (1998)
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