KEGG   Enterobacter cancerogenus: CWI88_04625Help
Entry
CWI88_04625       CDS       T05545                                 

Gene name
cobA
Definition
(GenBank) uroporphyrinogen-III C-methyltransferase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
ecan  Enterobacter cancerogenus
Pathway
ecan00860  Porphyrin and chlorophyll metabolism
ecan01100  Metabolic pathways
ecan01110  Biosynthesis of secondary metabolites
ecan01120  Microbial metabolism in diverse environments
Module
ecan_M00846  Siroheme biosynthesis, glutamate => siroheme
Brite
KEGG Orthology (KO) [BR:ecan00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    CWI88_04625 (cobA)
Enzymes [BR:ecan01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     CWI88_04625 (cobA)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     CWI88_04625 (cobA)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     CWI88_04625 (cobA)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M
Motif
Other DBs
NCBI-ProteinID: AUJ80370
UniProt: A0A2I6E206
Position
969400..970758
Genome map
AA seq 452 aa AA seqDB search
MDYLPLFAAIKDRPVLVVGSGEIAERKIAFLRRAGARIQVIEGEDFHDSLLDNVVLAIAA
TNDRAVNRRVFDAANARHRLVNVVDDQPLCSFIFPSIVDRSPLLIAISSGGNAPVLARLL
REKLEALLPASLGRMAEVAGNFRERLKTQVKTTDGRRRFWDRAFRGRFASLMAAGNERKA
GEVLEASLTQPEQAQGEIILVGAGPGDAGLLTLRGLQVIQQADVVFYDHLVTDGVRELIR
RDAEQICVGKRAGEHSVAQHETNAMLVAAAKAGKTVVRLKGGDPFIFGRGGEELQAAADA
GVPFQVVPGITAASAVTAYAGIPLTHRDYAQSVTFVTGHYKADSTPFDWSHLAQSRQTLA
IYMGTMKAADISEQLIQHGRDATTPVAVISRGTRVDQHVATGTLHDLARLAKDAPMPALI
VVGEVVQLHDTLAWFQHTTDAENLRSSVVTLA
NT seq 1359 nt NT seq  +upstreamnt  +downstreamnt
gtggattacctgcctttatttgctgccattaaagatcgtccggtgctggttgttggctcg
ggcgagatcgccgaacgcaaaattgcctttttgcggcgggctggcgcgcgcatacaggtg
atcgaaggcgaggattttcacgactcgctgctcgataacgtggtgctggcgattgccgcc
accaacgatcgtgcggttaatcgccgggtcttcgacgccgccaatgcgcgccaccgtctg
gtcaacgtggtggatgaccagccgctctgctcatttatctttccctcgattgtcgatcgt
tccccgctgctgattgctatctcctccggtgggaatgcgcccgtgctggcgcgcctgctg
cgtgaaaagcttgaagcgctgcttcccgcaagcctcggacggatggcggaggtggcaggg
aacttccgcgagcggctcaaaacgcaggtgaaaaccaccgacggacgccgtcgattctgg
gatcgtgccttccggggacgcttcgccagcctgatggccgcgggcaatgaacgtaaggcg
ggggaggtgcttgaagcctcgctgacgcagcccgagcaggcgcagggggagattattctg
gtgggggccgggccgggcgatgcggggctgttgaccctgcgcggcctgcaggtgatccag
caggcggatgtcgtcttttacgatcatctggtcaccgacggcgtgcgcgagttgatccgc
cgcgacgcagagcaaatctgcgtgggcaaacgcgccggtgagcactcggtggcgcagcat
gaaaccaatgcaatgctggttgcggcggcaaaagcgggcaaaaccgtggtgcgcctgaag
ggcggcgatccctttatcttcgggcgcggcggcgaggagctgcaggcggcggccgacgcg
ggcgtaccgttccaggtggtgcccggcattacggcggcgtccgctgttacggcctacgcc
ggcattccgctgacgcatcgtgactatgcccagagcgtgacctttgtcaccggccattac
aaggccgacagcacgccgtttgactggtcgcatctggcccagagccgtcagacgctggcg
atctacatgggcaccatgaaagcggccgacatcagcgaacagcttattcagcacggtcgc
gacgccacgacgcccgttgccgtgatttcacgcggcacgcgcgtcgatcagcacgttgcg
accggcacattacacgaccttgcacgcctcgcgaaagacgcgcccatgcccgccctgatc
gtggtgggggaagtggtgcagctgcacgacacgctcgcctggtttcaacatacaacagac
gcagagaacctccgttcttctgtggtgactctggcttaa

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