KEGG   Enterococcus casseliflavus: ECBG_00625
Entry
ECBG_00625        CDS       T02623                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
ecas  Enterococcus casseliflavus
Pathway
ecas00290  Valine, leucine and isoleucine biosynthesis
ecas00620  Pyruvate metabolism
ecas01100  Metabolic pathways
ecas01110  Biosynthesis of secondary metabolites
ecas01210  2-Oxocarboxylic acid metabolism
ecas01230  Biosynthesis of amino acids
Module
ecas_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:ecas00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    ECBG_00625
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    ECBG_00625
Enzymes [BR:ecas01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     ECBG_00625
SSDB
Motif
Pfam: HMGL-like LeuA_dimer EFhand_Ca_insen DUF6727
Other DBs
NCBI-GeneID: 15141834
NCBI-ProteinID: EEV38356
UniProt: C9A795
Position
1373723..1375243
AA seq 506 aa
MRKIQFFDTTLRDGEQTPGVNFNTKEKVQLALQLEKWGIDTIEAGFPIASEGDFQAVQAI
AGAVTKMTVAGLARCQKKDIDRAYEALHQAVDPQIHVFLATSEVHRQYKLNMTKAEVLAS
IKEHVAYARERFEKVQFSPEDATRTDKPFLLEAVQTAIDAGATIINVPDTVGFTNPTEYG
ALFAYLIANIKSEQPIIFSSHCHDDLGMATANALAAIENGADRVEGTINGIGERAGNTAL
EEVALALHIRNDFYQATSNIKLNETKRTSDLVARLSGITVPKNKAIVGGNAYAHESGIHQ
DGVLKNPETYEIITPQLVGVQTNSLPLGKLSGRHAFVDKMQQLGYQFDQEETNELFKRFK
ELADKKKQVTEQDLLALVADQGRSQEDGCELESVQLQYVSNGHQGAVVSIIKDEEKQVAS
AIGAGSIQAIYNSIDQIFQQQPKLLNYEITALTSGEDAQAEVHVVIECQETNEKISGIGL
DFDVLQASAKAYVQASAALKNRGVLV
NT seq 1521 nt   +upstreamnt  +downstreamnt
atgagaaaaatccagttttttgacaccacattgagagacggtgaacagacgccgggagtc
aacttcaatacaaaagagaaggttcaactggcgctgcaattagaaaaatgggggatcgat
acgatcgaagcaggctttccgattgcatcagaaggagactttcaagcagtccaagcgatt
gctggggcggtgacgaaaatgaccgttgcaggacttgcccgttgtcagaaaaaagacatt
gatcgtgcctatgaagctcttcatcaagccgtcgatccccagatccatgtctttttagca
acgagtgaggtacatcgccagtacaagctgaatatgacgaaagcagaagtactcgcttcc
atcaaagaacatgtggcttatgcccgtgaacgctttgaaaaagtccaattctcgccagaa
gatgccacccgcaccgataagcccttcttgcttgaggcggttcaaacagcgattgatgcc
ggcgcgacgatcatcaatgtgcccgatacagtagggtttaccaatcctacggaatatggt
gcgctttttgcctatttgatcgccaatatcaagagtgagcagccgatcattttttcttcc
cattgtcatgatgacttgggaatggcgacagccaatgcgctggcagctatcgaaaatggt
gctgatcgggtggaaggaacgatcaacgggatcggcgaacgagcgggcaataccgcacta
gaagaagtggcgctggcgttgcatattcgcaatgatttctatcaggctacctccaacatc
aagttaaacgaaacaaaacgcaccagcgatctggtggcacgtttgtctgggatcacggta
ccgaaaaacaaagcgatcgtcggcggcaatgcctatgctcatgaatctgggattcatcaa
gatggcgtcttgaaaaatcctgaaacttacgaaatcattaccccgcaactggtaggcgta
caaaccaactcactgcctcttggcaaactttctggccgccatgcgtttgtcgataaaatg
cagcagctggggtaccagtttgaccaagaagaaaccaatgaattgtttaaacgcttcaaa
gagttggcagataagaaaaagcaagtgaccgaacaagatttgttagcgttggtggctgac
cagggccgcagccaagaagatggctgcgagttggagtcagttcagctgcaatacgtgtcc
aatggccatcaaggagcggtggtttctatcatcaaagacgaggaaaaacaagtggcatca
gctatcggtgccggcagtatccaagctatctacaactcgatcgatcagattttccagcaa
cagccgaagttgttgaactatgagatcactgccttgaccagtggggaagatgcgcaagcg
gaagtgcacgtggttattgaatgccaggaaaccaatgaaaaaatcagtgggatcggctta
gactttgatgtcttgcaggcgtcagccaaagcctatgtacaggctagcgcagctctaaag
aatcgaggtgtccttgtttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (28)   

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