KEGG   Equus caballus (horse): 100033889Help
Entry
100033889         CDS       T01058                                 

Gene name
PLA2G4A
Definition
(RefSeq) cytosolic phospholipase A2
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
ecb  Equus caballus (horse)
Pathway
ecb00564  Glycerophospholipid metabolism
ecb00565  Ether lipid metabolism
ecb00590  Arachidonic acid metabolism
ecb00591  Linoleic acid metabolism
ecb00592  alpha-Linolenic acid metabolism
ecb01100  Metabolic pathways
ecb04010  MAPK signaling pathway
ecb04014  Ras signaling pathway
ecb04072  Phospholipase D signaling pathway
ecb04217  Necroptosis
ecb04270  Vascular smooth muscle contraction
ecb04370  VEGF signaling pathway
ecb04611  Platelet activation
ecb04664  Fc epsilon RI signaling pathway
ecb04666  Fc gamma R-mediated phagocytosis
ecb04724  Glutamatergic synapse
ecb04726  Serotonergic synapse
ecb04730  Long-term depression
ecb04750  Inflammatory mediator regulation of TRP channels
ecb04912  GnRH signaling pathway
ecb04913  Ovarian steroidogenesis
ecb04921  Oxytocin signaling pathway
ecb05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    100033889 (PLA2G4A)
   00565 Ether lipid metabolism
    100033889 (PLA2G4A)
   00590 Arachidonic acid metabolism
    100033889 (PLA2G4A)
   00591 Linoleic acid metabolism
    100033889 (PLA2G4A)
   00592 alpha-Linolenic acid metabolism
    100033889 (PLA2G4A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    100033889 (PLA2G4A)
   04010 MAPK signaling pathway
    100033889 (PLA2G4A)
   04370 VEGF signaling pathway
    100033889 (PLA2G4A)
   04072 Phospholipase D signaling pathway
    100033889 (PLA2G4A)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100033889 (PLA2G4A)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100033889 (PLA2G4A)
   04664 Fc epsilon RI signaling pathway
    100033889 (PLA2G4A)
   04666 Fc gamma R-mediated phagocytosis
    100033889 (PLA2G4A)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100033889 (PLA2G4A)
   04913 Ovarian steroidogenesis
    100033889 (PLA2G4A)
   04921 Oxytocin signaling pathway
    100033889 (PLA2G4A)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    100033889 (PLA2G4A)
  09156 Nervous system
   04724 Glutamatergic synapse
    100033889 (PLA2G4A)
   04726 Serotonergic synapse
    100033889 (PLA2G4A)
   04730 Long-term depression
    100033889 (PLA2G4A)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100033889 (PLA2G4A)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    100033889 (PLA2G4A)
Enzymes [BR:ecb01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     100033889 (PLA2G4A)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PLA2_B C2
Motif
Other DBs
NCBI-GeneID: 100033889
NCBI-ProteinID: NP_001075312
Ensembl: ENSECAG00000024810
VGNC: 21513
UniProt: O77793
Position
5
AA seq 749 aa AA seqDB search
MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISSTPDSRKRT
RHFNNNINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTLSSMKVGEKKEV
PFIFNQVTEMILEMSLEVCSCPDLRFSMALCDQEKTFRQQRKENIKENMKKLLGPKKSEG
LYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYLAGLSGSSWYMSTLYSH
PDFPEKGPEEINKELMKNVSYDPLLLLTPQKIKRYVESLWKKKSSGQPVTFTDIFGMLIG
ETLIHNRMNTTLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYG
TFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEE
LENITAKHIVSNDSSDSDDESQEPKGTENEDAERDYQNDNQASWVHRMLMALVSDSALFN
TREGRAGKVHNFMLGLNLNTSYPLSPLRNFTTQESLDDDELDAAVADPDEFERIYEPLDV
KSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMN
KLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVPRETK
EEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKNAMVESIEYRR
QNPSRCSVSLSNVEARRFFNKEFLNKPTA
NT seq 2250 nt NT seq  +upstreamnt  +downstreamnt
atgtcatttatagatccttatcagcacattatagtggagcaccagtattcccacaagttc
acggtagtggtgttacgtgccaccaaagtgacaaagggggcctttggtgacatgcttgat
actccagatccctacgtggaacttttcatctcctcaacccctgacagcaggaagagaaca
agacacttcaataacaacataaaccccgtgtggaatgagacctttgaatttattttggat
ccgaatcaggaaaatgttttggagattacgttaatggatgccaattatgtcatggatgaa
actctagggacagcaacatttaccctatcgtctatgaaggtgggagagaagaaagaggtt
cctttcattttcaaccaagtcactgaaatgattctggaaatgtctcttgaagtttgttcg
tgcccagacctccgatttagtatggctctgtgtgatcaggagaagactttcagacaacag
agaaaagagaacataaaggaaaacatgaagaaactcctgggtccaaagaagagtgaaggc
ttgtattcaacacgtgatgtgcctgtggttgccatcttgggctcaggcggaggtttccga
gccatggtgggattctccggggtgatgaaggcattatatgagtcaggaattctggattgt
gctacctatctggctggtctttctggctccagctggtacatgtcaaccttgtattctcac
cctgattttccagagaaagggccagaggagattaataaagagctaatgaaaaatgttagc
tacgacccccttttacttctcacgccacagaaaattaagagatatgttgagtctttgtgg
aagaagaaaagctctggacaacctgtcacctttactgacatctttgggatgttaatagga
gaaacactaattcacaatagaatgaacactaccttgagtagtttgaaggaaaaggtcaat
actgcacagtgcccgttacctcttttcacctgtctccatgtgaaacccgatgtttcagag
ctgatgtttgcagattgggttgaatttagtccgtatgagattggcatggctaaatatggg
acttttatggctccagacttatttggaagcaaattttttatgggaacagtcgttaagaag
tatgaagaaaaccctttgcatttcttaatgggtgtctggggcagtgccttttctatattg
ttcaacagagtcttgggcgtttctggctcacaaaataaaggttccacaatggaggaagaa
ttagaaaatattacggcaaagcacattgtgagtaatgatagctcagatagcgatgatgag
tcacaagaacccaaaggcactgagaatgaagatgctgaaagggactatcaaaatgataat
caagcaagttgggtccatcgtatgttaatggccttggtgagtgactccgctttattcaat
accagagaaggacgtgctgggaaggtgcacaacttcatgctgggcttgaatctcaacaca
tcgtacccactgtctcctctgaggaactttaccacacaggagtccttggatgatgatgaa
ctggatgcagctgtagcagatcctgatgagtttgagcgaatatatgagcctctggatgtc
aaaagtaaaaagattcatgtagtggatagtggcctcacatttaacctgccgtacccgctg
atcctgagacctcaaagaggagttgatctcatcatctcctttgacttttctgcaaggcca
agcgactctagtcctccgttcaaggaacttctacttgcagaaaagtgggctaaaatgaac
aagctcccctttccaaagattgatccttatgtgtttgatagagaaggactgaaggagtgc
tatgtctttaaacccaagaatcctgatgtggagaaagattgcccaaccatcatccacttt
gttctggccaacatcaacttcaggaagtacaaggctccaggtgttccaagagaaactaag
gaagagaaagaaatagctgactttgatatttttgatgacccagaatcaccgttttcaacc
ttcaattttcaatatccaaatcaagcgttcaaacggctgcacgatctgatgcacttcaac
accctgaacaacattgacgtgattaagaatgccatggttgaaagcattgaatatagaagg
cagaatccgtctcgttgctctgtttccctcagtaatgttgaggcaagaagattcttcaac
aaggagtttctaaacaaacccacagcatag

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