KEGG   Equus caballus (horse): 100050182
Entry
100050182         CDS       T01058                                 
Symbol
ERBB4
Name
(RefSeq) receptor tyrosine-protein kinase erbB-4 isoform X6
  KO
K05085  receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
Organism
ecb  Equus caballus (horse)
Pathway
ecb04010  MAPK signaling pathway
ecb04012  ErbB signaling pathway
ecb04020  Calcium signaling pathway
ecb04151  PI3K-Akt signaling pathway
ecb05014  Amyotrophic lateral sclerosis
ecb05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100050182 (ERBB4)
   04012 ErbB signaling pathway
    100050182 (ERBB4)
   04020 Calcium signaling pathway
    100050182 (ERBB4)
   04151 PI3K-Akt signaling pathway
    100050182 (ERBB4)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100050182 (ERBB4)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100050182 (ERBB4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ecb01001]
    100050182 (ERBB4)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100050182 (ERBB4)
Protein kinases [BR:ecb01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   100050182 (ERBB4)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Kinase-like Haspin_kinase ABC1
Other DBs
NCBI-GeneID: 100050182
NCBI-ProteinID: XP_001488817
Ensembl: ENSECAG00000022865
VGNC: 17651
UniProt: A0A3Q2LCD3
Position
6:complement(1708313..2812168)
AA seq 1308 aa
MKLATGLWVWVSLLVAAGTVQPSASQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM
GNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF
LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYTDTIHWQDIVRNPWPSNLTLVST
NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG
PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD
SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLLSAQTVDSSNIDKFINCT
KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL
VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST
INQRIVIRDNRKAENCTAEGMVCNHLCSSNGCWGPGPDQCLSCRRFSRGRTCIESCNLFD
GEFREFENGSICVECDPQCEKMEDGILTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA
NSFIFKYADQDRECHPCHPNCTQGCSGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG
LFIMVIMALTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR
VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL
VRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV
HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ
SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID
ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE
EYLVPQAFNIPPPIYTSRARIDSNRSDIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVPVP
YRATTSTIPEAPVAQGATPEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFATERS
PRGELDEEGYMTPMRDKPKQEYLHPVEENPFVSRRKNGDLQALDNPEYHSASNGPPKAED
EYVNEPLYLNTFANALGNAEYLKNNVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ
EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV
NT seq 3927 nt   +upstreamnt  +downstreamnt
atgaagctggcgacaggactgtgggtctgggtgagccttctcgtggcggcggggaccgtc
cagcccagcgcttctcagtcagtgtgtgcaggaacagagaataagctgagctctctctct
gatctggagcagcagtatcgagccttgcgcaaatactatgagaactgtgaggtagtcatg
ggcaacctggagataaccagcatcgagcacaaccgggacctctcctttctgcggtctatt
cgagaagtcacaggctacgtgttagtggctcttaaccagtttcgttacctgcctctggag
aacttacgcattattcgtgggacaaaactttatgaggatcgatacgccttggcaatattt
ttaaactacagaaaagatggaaactttggacttcaggaacttggattgaagaacttgaca
gaaatcctaaatggtggagtctatgtagaccagaacaaattcctttgttacacagacaca
attcattggcaagacattgttcggaatccatggccttccaacttgactctggtgtcaaca
aatggtagctcaggatgtggacgttgccataagtcctgtactggccgatgctggggaccc
acagagaatcattgccagactttgacaaggacagtgtgtgcagaacaatgtgatggcagg
tgctacggaccctacgtcagtgactgctgtcatcgagaatgtgctgggggctgctcggga
cccaaggacaccgactgctttgcctgcatgaatttcaatgacagtggagcatgtgttact
cagtgtccccaaacttttgtctacaatccaaccacctttcagttggagcataacttcaat
gcaaagtacacgtatggagcattttgtgtcaagaagtgcccacataactttgtggtcgat
tccagttcttgtgtgcgtgcctgtcctagttccaagatggaagtagaagaaaatggtatt
aaaatgtgtaaaccttgcactgatatttgcccaaaagcttgcgatggcattggcacggga
tcactgctgtcagctcagactgtggattccagtaacattgacaaattcataaactgcacc
aaaatcaatgggaatttgatcttccttgtcactggtattcatggggacccttacaatgca
attgaagccatagacccagagaaactgaatgtctttcggaccgtccgagagataacaggt
ttcttgaacatacaatcatggcccccaaacatgaccgacttcagtgttttttctaacctg
gtgaccattggtggaagagtactctatagtggcctctccttgcttatcctcaagcaacag
ggcatcacttctctccaattccagtccctgaaggaaatcagtgcaggaaacatctatatt
acagacaacagcaacctgtgctattatcacaccattaactggacaacgctcttcagcact
atcaaccaaagaatagtgatccgggacaacaggaaagctgaaaactgtactgctgaagga
atggtatgtaaccatctgtgctcaagcaatggctgctggggacccgggccagaccagtgc
ctgtcctgccgtcgcttcagcagggggaggacctgcatagagtcctgtaacctctttgat
ggcgaatttcgggagtttgagaatggctccatctgtgtggagtgtgacccccagtgtgag
aagatggaagatggcatcctcacatgccatggaccgggacctgacaactgtaccaagtgc
tcccattttaaggatggcccgaactgtgtggaaaaatgtccagatggcctgcagggtgca
aacagtttcatcttcaagtatgctgatcaggatcgggagtgccacccatgccatccaaac
tgcacccaagggtgtagcggtcccactagtcatgactgcatttactacccttggacgggc
cattccactttaccacaacatgctaggactcctctaattgcagcgggagttatcggcggg
ctcttcatcatggtcatcatggctctaacattcgcagtttatgttagaaggaagagcatc
aaaaagaaaagagccttgagaaggttcctggaaacagagctggtagaacccttaactccc
agtggcacagcccccaatcaagctcaacttcgcattttgaaagaaactgagctcaaaaga
gtgaaagtacttggctcgggtgcttttggaactgtttataaaggtatttgggtccctgaa
ggagaaacagtgaagattcctgtagctattaagattcttaatgaaacaactggtcccaaa
gccaatgtggagtttatggatgaagctctgatcatggcaagtatggaccatccacactta
gtccggttattgggtgtctgtctgagcccaactatccagctggttacacagcttatgccc
catggctgcctgttggattacgtccatgaacacaaggataacattggatcacagctgtta
cttaactggtgtgtccagatagcgaagggaatgatgtacctggaagaaaggcggctcgtt
catcgggacttggcagcccgtaatgtcttagtgaaatctccaaaccatgtgaaaatcaca
gattttggactagccagactcttggaaggagacgaaaaagagtataacgctgacggagga
aagatgccaattaagtggatggctctggagtgtatacactataggaaattcacccaccag
agtgatgtttggagctatggagtcactatttgggaactgatgacctttggaggaaaaccc
tacgatggaattccaacccgagaaatccctgatttattagagaaaggagaacgtttgccc
cagcctcccatctgcactattgatgtctacatggtcatggtcaaatgttggatgattgat
gctgacagtagacctaaatttaaagaactggccgctgaattttcgaggatggctcgagac
cctcagagatatctagttattcagggtgatgatcgtatgaaacttcccagtccaaacgac
agcaagttctttcagaatctcttggatgaagaggatttagaggatatgatggatgctgag
gaatacctggtccctcaggctttcaacatcccacctcccatctatacttccagagcaaga
attgactcaaataggagtgacattggacacagccctcctcctgcctacacccccatgtca
ggaaaccagtttgtgtaccgagacggaggttttgccgcagaacaaggagtgcccgtgccc
tacagagccaccaccagcaccatcccagaagctcccgttgctcagggggctacccccgag
attttcgatgactcctgctgtaacggcaccctgcgcaagccagtggcaccccatgtccaa
gaggatagcagcacccagaggtacagcgccgaccccacagtgtttgccacagaacggagc
ccacgaggagagctggatgaggaaggttacatgacccctatgcgagacaaacccaaacaa
gagtacctgcaccctgtggaagagaacccttttgtttctcgaagaaaaaatggagacctt
caagctttggataatcctgaatatcacagtgcttccaacggtccgcccaaggcagaggat
gagtatgtgaatgagccactgtacctcaacacctttgccaacgccttggggaatgccgag
tacctgaagaacaacgtactgtctgtgccagagaaggccaagaaggcattcgacaaccct
gactactggaaccacagcctgccgcctcggagcacccttcagcacccagactacctgcag
gagtacagcacaaaatatttttataaacaaaatggacggatccggcctattgtggcagag
aatcctgaatacctctctgagttctcattgaagccaggcactgtgctgcctcctccaccc
tacagacaccgaaatactgtggtgtaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (11)   
   UniProt (1)   
   RefSeq(pep) (10)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (9)   
   Pfam (9)   
All databases (66)   

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