KEGG   Equus caballus (horse): 100052828Help
Entry
100052828         CDS       T01058                                 

Gene name
PRKACB
Definition
(RefSeq) cAMP-dependent protein kinase catalytic subunit beta isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
ecb  Equus caballus (horse)
Pathway
ecb01522  Endocrine resistance
ecb04010  MAPK signaling pathway
ecb04014  Ras signaling pathway
ecb04020  Calcium signaling pathway
ecb04024  cAMP signaling pathway
ecb04062  Chemokine signaling pathway
ecb04114  Oocyte meiosis
ecb04140  Autophagy - animal
ecb04211  Longevity regulating pathway
ecb04213  Longevity regulating pathway - multiple species
ecb04261  Adrenergic signaling in cardiomyocytes
ecb04270  Vascular smooth muscle contraction
ecb04310  Wnt signaling pathway
ecb04340  Hedgehog signaling pathway
ecb04371  Apelin signaling pathway
ecb04530  Tight junction
ecb04540  Gap junction
ecb04611  Platelet activation
ecb04713  Circadian entrainment
ecb04714  Thermogenesis
ecb04720  Long-term potentiation
ecb04723  Retrograde endocannabinoid signaling
ecb04724  Glutamatergic synapse
ecb04725  Cholinergic synapse
ecb04726  Serotonergic synapse
ecb04727  GABAergic synapse
ecb04728  Dopaminergic synapse
ecb04740  Olfactory transduction
ecb04742  Taste transduction
ecb04750  Inflammatory mediator regulation of TRP channels
ecb04910  Insulin signaling pathway
ecb04911  Insulin secretion
ecb04912  GnRH signaling pathway
ecb04913  Ovarian steroidogenesis
ecb04914  Progesterone-mediated oocyte maturation
ecb04915  Estrogen signaling pathway
ecb04916  Melanogenesis
ecb04918  Thyroid hormone synthesis
ecb04919  Thyroid hormone signaling pathway
ecb04921  Oxytocin signaling pathway
ecb04922  Glucagon signaling pathway
ecb04923  Regulation of lipolysis in adipocytes
ecb04924  Renin secretion
ecb04925  Aldosterone synthesis and secretion
ecb04926  Relaxin signaling pathway
ecb04927  Cortisol synthesis and secretion
ecb04928  Parathyroid hormone synthesis, secretion and action
ecb04934  Cushing's syndrome
ecb04961  Endocrine and other factor-regulated calcium reabsorption
ecb04962  Vasopressin-regulated water reabsorption
ecb04970  Salivary secretion
ecb04971  Gastric acid secretion
ecb04976  Bile secretion
ecb05012  Parkinson's disease
ecb05020  Prion diseases
ecb05030  Cocaine addiction
ecb05031  Amphetamine addiction
ecb05032  Morphine addiction
ecb05146  Amoebiasis
ecb05165  Human papillomavirus infection
ecb05166  HTLV-I infection
ecb05169  Epstein-Barr virus infection
ecb05200  Pathways in cancer
ecb05203  Viral carcinogenesis
ecb05205  Proteoglycans in cancer
ecb05414  Dilated cardiomyopathy (DCM)
Module
ecb_M00695  cAMP signaling
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100052828 (PRKACB)
   04010 MAPK signaling pathway
    100052828 (PRKACB)
   04310 Wnt signaling pathway
    100052828 (PRKACB)
   04340 Hedgehog signaling pathway
    100052828 (PRKACB)
   04371 Apelin signaling pathway
    100052828 (PRKACB)
   04020 Calcium signaling pathway
    100052828 (PRKACB)
   04024 cAMP signaling pathway
    100052828 (PRKACB)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    100052828 (PRKACB)
  Cell growth and death
   04114 Oocyte meiosis
    100052828 (PRKACB)
  Cellular community - eukaryotes
   04530 Tight junction
    100052828 (PRKACB)
   04540 Gap junction
    100052828 (PRKACB)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100052828 (PRKACB)
   04062 Chemokine signaling pathway
    100052828 (PRKACB)
  Endocrine system
   04911 Insulin secretion
    100052828 (PRKACB)
   04910 Insulin signaling pathway
    100052828 (PRKACB)
   04922 Glucagon signaling pathway
    100052828 (PRKACB)
   04923 Regulation of lipolysis in adipocyte
    100052828 (PRKACB)
   04912 GnRH signaling pathway
    100052828 (PRKACB)
   04913 Ovarian Steroidogenesis
    100052828 (PRKACB)
   04915 Estrogen signaling pathway
    100052828 (PRKACB)
   04914 Progesterone-mediated oocyte maturation
    100052828 (PRKACB)
   04921 Oxytocin signaling pathway
    100052828 (PRKACB)
   04926 Relaxin signaling pathway
    100052828 (PRKACB)
   04918 Thyroid hormone synthesis
    100052828 (PRKACB)
   04919 Thyroid hormone signaling pathway
    100052828 (PRKACB)
   04928 Parathyroid hormone synthesis, secretion and action
    100052828 (PRKACB)
   04916 Melanogenesis
    100052828 (PRKACB)
   04924 Renin secretion
    100052828 (PRKACB)
   04925 Aldosterone synthesis and secretion
    100052828 (PRKACB)
   04927 Cortisol synthesis and secretion
    100052828 (PRKACB)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100052828 (PRKACB)
   04270 Vascular smooth muscle contraction
    100052828 (PRKACB)
  Digestive system
   04970 Salivary secretion
    100052828 (PRKACB)
   04971 Gastric acid secretion
    100052828 (PRKACB)
   04976 Bile secretion
    100052828 (PRKACB)
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    100052828 (PRKACB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100052828 (PRKACB)
  Nervous system
   04724 Glutamatergic synapse
    100052828 (PRKACB)
   04727 GABAergic synapse
    100052828 (PRKACB)
   04725 Cholinergic synapse
    100052828 (PRKACB)
   04728 Dopaminergic synapse
    100052828 (PRKACB)
   04726 Serotonergic synapse
    100052828 (PRKACB)
   04720 Long-term potentiation
    100052828 (PRKACB)
   04723 Retrograde endocannabinoid signaling
    100052828 (PRKACB)
  Sensory system
   04740 Olfactory transduction
    100052828 (PRKACB)
   04742 Taste transduction
    100052828 (PRKACB)
   04750 Inflammatory mediator regulation of TRP channels
    100052828 (PRKACB)
  Aging
   04211 Longevity regulating pathway - mammal
    100052828 (PRKACB)
   04213 Longevity regulating pathway - multiple species
    100052828 (PRKACB)
  Environmental adaptation
   04713 Circadian entrainment
    100052828 (PRKACB)
   04714 Thermogenesis
    100052828 (PRKACB)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100052828 (PRKACB)
   05205 Proteoglycans in cancer
    100052828 (PRKACB)
   05203 Viral carcinogenesis
    100052828 (PRKACB)
  Neurodegenerative diseases
   05012 Parkinson's disease
    100052828 (PRKACB)
   05020 Prion diseases
    100052828 (PRKACB)
  Substance dependence
   05030 Cocaine addiction
    100052828 (PRKACB)
   05031 Amphetamine addiction
    100052828 (PRKACB)
   05032 Morphine addiction
    100052828 (PRKACB)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    100052828 (PRKACB)
  Endocrine and metabolic diseases
   04934 Cushing's syndrome
    100052828 (PRKACB)
  Infectious diseases
   05166 HTLV-I infection
    100052828 (PRKACB)
   05163 Human cytomegalovirus infection
    100052828 (PRKACB)
   05169 Epstein-Barr virus infection
    100052828 (PRKACB)
   05165 Human papillomavirus infection
    100052828 (PRKACB)
   05146 Amoebiasis
    100052828 (PRKACB)
  Drug resistance
   01522 Endocrine resistance
    100052828 (PRKACB)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     100052828 (PRKACB)
Protein kinases [BR:ecb01001]
 Serine/threonine kinases: AGC group
  PKA family
   100052828 (PRKACB)
Messenger RNA biogenesis [BR:ecb03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     100052828 (PRKACB)
Chromosome and associated proteins [BR:ecb03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Kinases and associated factors
    100052828 (PRKACB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr Kinase-like
Motif
Other DBs
NCBI-GeneID: 100052828
NCBI-ProteinID: XP_001497490
Ensembl: ENSECAG00000022585
VGNC: 21838
Position
5
AA seq 397 aa AA seqDB search
MATYRELPCNQCTGTTALQKLEGFANRLFHRHSKSFTHDQKTALENDSLHFSEHTASWDR
SMKEFLAKAKEDFLKKWENPAQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKI
LDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLR
RIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG
RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG
KVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAP
FIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFCEF
NT seq 1194 nt NT seq  +upstreamnt  +downstreamnt
atggcaacttacagagaactaccctgtaaccagtgtacaggtacaactgctcttcagaaa
ttggaaggttttgctaaccgactatttcatagacactctaaaagttttacccatgatcag
aaaacagctctggaaaatgacagccttcatttctctgaacatactgcctcatgggacaga
tcaatgaaagagtttctagctaaagccaaagaagactttttaaaaaaatgggaaaatcct
gctcagaataatgccgggctggaggattttgaaaggaaaaaaacccttggaacaggttca
tttggaagagtcatgttggtgaaacataaagccactgaacagtattatgccatgaagatc
ttagataagcagaaggttgttaaactgaagcaaatagagcatactttgaatgagaaaaga
atattacaggcagtgaattttccttttcttgttcgactggagtattcttttaaggataat
tctaatttatacatggttatggaatatgtccccgggggtgaaatgttttcacatttaaga
agaattggaaggttcagtgaaccccatgcacggttctatgcagctcagatagtgctaaca
ttcgagtacctccattcactagacctcatctacagagatctaaaacctgaaaatctctta
attgaccaccaaggttatatccaggtcacagactttgggtttgccaaaagagttaaaggc
agaacttggacattatgtggcactccagaatatttagctccagaaataatcctcagcaag
ggttacaataaggcagtggattggtgggccttaggagtgttaatctatgaaatggcagct
ggctaccccccgttctttgcagatcaaccaattcaaatttatgaaaagattgtttctgga
aaggtccgattcccatcacacttcagttcagatctcaaggacctcctaaggaacctactg
caggtggatttgacaaagcggtttggaaatctaaagaatggtgtgagtgacataaaaact
cacaagtggtttgccacaacagattggattgcgatttaccagaggaaggttgaagctcca
ttcataccaaagttcagaggctctggagataccagcaactttgatgactatgaagaagaa
gatatccgtgtctctataacagaaaaatgtgcaaaagaattttgtgaattttga

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