KEGG   Equus caballus (horse): 100054547
Entry
100054547         CDS       T01058                                 
Symbol
PTK2B
Name
(RefSeq) protein-tyrosine kinase 2-beta isoform X1
  KO
K05871  focal adhesion kinase 2 [EC:2.7.10.2]
Organism
ecb  Equus caballus (horse)
Pathway
ecb04020  Calcium signaling pathway
ecb04062  Chemokine signaling pathway
ecb04072  Phospholipase D signaling pathway
ecb04650  Natural killer cell mediated cytotoxicity
ecb04670  Leukocyte transendothelial migration
ecb04912  GnRH signaling pathway
ecb05135  Yersinia infection
ecb05161  Hepatitis B
ecb05163  Human cytomegalovirus infection
ecb05170  Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    100054547 (PTK2B)
   04072 Phospholipase D signaling pathway
    100054547 (PTK2B)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100054547 (PTK2B)
   04670 Leukocyte transendothelial migration
    100054547 (PTK2B)
   04062 Chemokine signaling pathway
    100054547 (PTK2B)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100054547 (PTK2B)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100054547 (PTK2B)
   05161 Hepatitis B
    100054547 (PTK2B)
   05163 Human cytomegalovirus infection
    100054547 (PTK2B)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100054547 (PTK2B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ecb01001]
    100054547 (PTK2B)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     100054547 (PTK2B)
Protein kinases [BR:ecb01001]
 Non-receptor tyrosine kinases
  FAK family
   100054547 (PTK2B)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Focal_AT FERM_N_2 Pkinase FERM_C_FAK1 FERM_M Kinase-like FERM_F2 UCH Haspin_kinase
Other DBs
NCBI-GeneID: 100054547
NCBI-ProteinID: XP_023491958
Ensembl: ENSECAG00000018924
VGNC: 22003
Position
2:56278249..56401538
AA seq 1009 aa
MSGVSEPLSRVKVGTLRRPEGPPEPMVVVPADVEKEDVRILKVCFYSNSFNPGKNFKLVK
CTVHTEIREVIASILLSGRIGPNIQLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYEC
LHMEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
LELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDTKPTCLA
EFKQIKSIRCLPLEEGQAVLQLGIEGAPQSLSIKTSSLAEAENMADLIDGYCRLQGEHKG
SLIIHPKKDGEKRNSLPQIPVLNLETQRSRLSESCSIESDIYAEIPDETLRRPGGPQYGI
AREDVVLSRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKN
LDHPHIVKLIGIIEEEPTWIIMELYPFGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
ESINCVHRDIAVRNILVASANCVKLGDFGLSRYIEDEEYYKASVTRLPIKWMAPESINFR
RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPILYTLMTR
CWDYDPSERPRFTELVCSLSDVYQMEKDIDTEQERNARYRPPKILEPTALQEPPPKPSRP
KYRTPPQTNLLAPTLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
EGDFVRPSSREEAQQLWEAERVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
LTPEKEPGYTEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLDLKNELCQ
LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
NT seq 3030 nt   +upstreamnt  +downstreamnt
atgtctggggtgtccgagcccctgagccgagtgaaggtgggcacgttacgtcggccggag
ggccccccggagcccatggtggtggtgccagcagacgtggaaaaggaagacgtgcggatc
ctcaaggtctgcttctatagcaacagcttcaaccccgggaagaacttcaagctggtgaaa
tgcacggtgcacaccgagatccgggaggtcattgcctccatcctgctgagtgggcggatc
gggcccaacatccagctggctgagtgctatgggctgaggctgaagcacatgaagtcggat
gagatccactggctgcacccgcagatgacggtgggtgaggtgcaggacaagtatgagtgt
ctacacatggaagccgagtggaggtatgaccttcaaatccgctacttgcccgaggacttc
atggagagcctgaaagaagataggaccacactgctttatttttaccaacagctccggaat
gactacatgcagcgctacgccagcaaggtcagcgagggcatggccctacagctgggctgc
ctggagctcaggaggttcttcaaggacatgccccacaatgcactcgacaaaaagtccaac
ttcgagctcctagagaaggaagtgggactggacctgtttttcccaaagcagatgcaagag
aacttaaagcccaagcagttccggaagatgatccagcagacgttccagcagtacgcctcg
ctcagggaggaggagtgcgtcatgaagttcttcaacaccctcgcgggctttgccaacatc
gaccaggagacctatcgctgtgaactcattcaaggttggaacattactgtggacctggtc
atcggcccgaaaggcatccgccagctgacaagccaagatacaaagcccacctgcctggcc
gagttcaagcagatcaagtccatcaggtgcctgcccctggaggagggccaggcggtactg
cagttgggcattgaaggcgccccccagtccttgtccatcaaaacctcctctctggcagag
gctgagaacatggctgacctcatagacggttactgccggctgcagggggagcacaaaggc
tctctcatcattcatcccaagaaagatggtgagaagcggaacagcctgccccagatcccg
gtgctgaacctggagactcagcggtcccgcctctcagaaagctgtagcatagaatcagac
atctatgcagagattcccgacgagaccctgcgaaggccaggaggcccacagtatggcatc
gcccgggaagatgtggttctgagtcgcattcttggtgaaggcttttttggggaggtctac
gaaggtgtctacacaaatcacaaaggggagaaaatcaatgtggctgtgaagacctgcaag
aaggactgtactctcgacaacaaggagaagttcatgagtgaggcagtgatcatgaagaac
ctcgaccacccgcacattgtgaagctcatcggcatcatcgaagaggagcccacctggatc
atcatggaactgtatcccttcggggagctgggccactacctggagcggaacaagaactcc
ctgaaggtactcactctcgtcctgtactcgctgcagatttgcaaggccatggcctacctg
gagagcatcaactgtgtgcacagggacatcgccgtccgaaatatcctggtggcctctgct
aactgtgtgaagctgggggactttggcctctcccgatacattgaggacgaggagtattac
aaagcctctgtgactcggctccccatcaaatggatggcccccgagtccattaacttccgc
cgcttcacgacggccagcgacgtctggatgtttgccgtgtgcatgtgggagatcctgagc
tttgggaagcagcccttcttctggctggagaacaaggatgtcatcggggtgctggagaag
ggggaccggctgcccaagcccgacctctgcccgcctattctctacaccctcatgacccgc
tgctgggactacgaccccagcgagcggccccgctttaccgagctcgtgtgcagcctcagt
gacgtttatcagatggagaaagacatcgacacagagcaggagaggaatgctcgctatcga
cctcccaaaatcttggagcccacagccctccaggagcccccacccaagcccagccgcccc
aagtacagaacccctccacaaaccaaccttctggctcccacactgcagttccaggtcccc
gagggtctgtgtgccagctcacctacgctcaccagccctatggagtacccatctcctgta
aactcgctgcacaccccgcctctccaccggcacaatgtcttcaagcgccacagcatgcgg
gagggggacttcgtccgacccagcagccgagaagaggcccagcagctctgggaggccgag
agggtcaagatgcggcagatcctggataagcagcagaagcagatggtggaagattaccag
tggctgaggcaggaggagaaatccttggaccccatggtttacatgaacgataagtccccg
ttgaccccggagaaggagcctggctacacagagttcacgggacccccacagaagccaccg
cggctgggcgctcagtccatccagcccacagccaacctggaccgcaccgacgacctggtg
tacctcaacgtcatggagctggtgcgggctgtgctggacctcaagaacgagctctgtcag
ctgcctcccgagggctacgtggtggtggtgaagaacgtgggcctgaccctgcggaagctc
atcgggagcgtggacgatctcctgccctccttgccgtcatcttcacggaccgagattgag
gggacccagaaactgctcaacaaggacctggctgagctcatcaataagatgcggctggcc
cagcaaaatgccgtgacctccctgagcgaggagtgcaagcgacagatgctcacagcctcc
cacaccctggctgtggacgccaagaacctgctcgatgctgtggaccaggccaaggttctg
gccaacctggcccacccgcctgcagagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (10)   
   Pfam (10)   
All databases (46)   

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