KEGG   Equus caballus (horse): 100059277
Entry
100059277         CDS       T01058                                 
Name
(RefSeq) steroid 21-hydroxylase
  KO
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Organism
ecb  Equus caballus (horse)
Pathway
ecb00140  Steroid hormone biosynthesis
ecb01100  Metabolic pathways
ecb04925  Aldosterone synthesis and secretion
ecb04927  Cortisol synthesis and secretion
ecb04934  Cushing syndrome
Module
ecb_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100059277
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    100059277
   04927 Cortisol synthesis and secretion
    100059277
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100059277
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ecb00199]
    100059277
Enzymes [BR:ecb01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     100059277
Cytochrome P450 [BR:ecb00199]
 Cytochrome P450, animal type
  CYP21 family
   100059277
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 100059277
NCBI-ProteinID: XP_001491972
Ensembl: ENSECAG00000016208
Position
20:32578662..32581819
AA seq 493 aa
MLLLGLLLLLILLAGARLLWGQWKLRSLHLPPLVPGFLHLLQPNLPIYLLGLTQKLGPIY
RLRLGLQAVVVLNSKRTIEEAMIRKWVDFAGRPELLSYKLVSQRYQDLSLGDYSLLWKAH
KKLTRSALLLGIRNSMEPLVEQLTQEFCERMRAQAGAPVAIQKEFSFLTCSIICYLTFGD
KEDTLVHAIQDCVQDLMRTWEHWSIQILDIIPFLRFFPNPGLWRLKQAMENRDHIIEKQL
RQHKESIVAGRWRDMTDYMLQGLGRPTVEEAPGQLLEGHVHMAMVDLFIGGTETTASTLS
WAVAFLLHHPEIQQRLQDELDRELGPRALGSTVPFKDRARLPLLNATIAEVLRLRPVVPL
ALPHRTTRPTSIVGYDIPKGTIIIPNLQGAHLDETIWEQPHEFRPDRFLYPGASPSTLAF
GCGARVCLGEPLARLELFVVLAQLLRAFTLLPPAGALPSLQPQPHCGVNLTMQPFQVQLQ
PRGAGTPGLGERQ
NT seq 1482 nt   +upstreamnt  +downstreamnt
atgctactccttgggctgctgctgctgctgatcttgctggcaggcgcccgcctgctctgg
ggtcagtggaagctcaggagcctccaccttccacctcttgtccctggcttcctgcacctg
ctgcagcccaacctccccatctatctgcttggcttgactcagaaacttgggcctatctac
aggctccgcctcgggctgcaagctgtggtggtgctgaactccaagaggaccattgaagaa
gccatgatcaggaagtgggtggactttgctggcagacccgagttactatcttataagctg
gtgtctcagcgctaccaggatctctcactaggggactattccctgctctggaaggcccac
aagaaactcacccgctcagccctgctactgggcatccgcaactccatggagcccctggtg
gaacagctgacccaagagttctgtgagcgcatgagagcccaggccggtgcccccgtggcc
atccagaaggaattctctttcctcacctgcagcatcatctgttacctcacttttggagac
aaggaagacaccttagtacatgccattcaggactgtgtccaggacttgatgagaacctgg
gaacactggtccatccaaattctggacatcattccctttctcaggttcttccccaaccca
ggcctctggagactgaagcaggccatggagaacagagatcacatcatagagaagcagctg
aggcagcacaaggagagcatagtggcaggccggtggagggacatgacagactacatgctc
caaggactgggcaggccgacagtggaagaggcccctggacagctccttgaagggcacgtg
catatggctatggtggaccttttcatcggtggaacggagaccactgcgagcaccctctcc
tgggctgtggcattcttgcttcaccaccctgagattcagcagcgactgcaggacgagttg
gatcgtgagctgggccccagagccttgggctccacagtcccattcaaagaccgcgcacgg
ctacccttgctcaacgccactatcgccgaggtgctgcgcctgcggccggtcgtgcccctg
gccttgccgcaccgcaccacgcggcctaccagcatcgtcggctacgacatccccaagggc
acaatcattatccccaacctccaaggcgcccacctggatgagacgatttgggagcagccg
cacgagttccggccggaccgcttcctgtaccccggcgccagccccagcacgctcgccttc
ggctgcggggcgcgcgtgtgcctgggcgagccgctggcgcgcctcgagctcttcgtggtg
ctggcgcagctgctccgcgccttcacgctgctgccgcccgccggcgccctgccctctttg
cagccccagccccactgcggcgtcaacctcaccatgcagcctttccaggtgcagctgcag
ccccgtggagcggggaccccgggcctgggcgagcgccagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (5)   
   KEGG MODULE (2)   
Chemical substance (16)   
   KEGG COMPOUND (16)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (1)   
   Pfam (1)   
All databases (44)   

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