KEGG   Equus caballus (horse): 100071038Help
Entry
100071038         CDS       T01058                                 

Gene name
PLA2G4E
Definition
(RefSeq) cytosolic phospholipase A2 epsilon
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
ecb  Equus caballus (horse)
Pathway
ecb00564  Glycerophospholipid metabolism
ecb00565  Ether lipid metabolism
ecb00590  Arachidonic acid metabolism
ecb00591  Linoleic acid metabolism
ecb00592  alpha-Linolenic acid metabolism
ecb01100  Metabolic pathways
ecb04010  MAPK signaling pathway
ecb04014  Ras signaling pathway
ecb04072  Phospholipase D signaling pathway
ecb04217  Necroptosis
ecb04270  Vascular smooth muscle contraction
ecb04370  VEGF signaling pathway
ecb04611  Platelet activation
ecb04664  Fc epsilon RI signaling pathway
ecb04666  Fc gamma R-mediated phagocytosis
ecb04724  Glutamatergic synapse
ecb04726  Serotonergic synapse
ecb04730  Long-term depression
ecb04750  Inflammatory mediator regulation of TRP channels
ecb04912  GnRH signaling pathway
ecb04913  Ovarian steroidogenesis
ecb04921  Oxytocin signaling pathway
ecb05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    100071038 (PLA2G4E)
   00565 Ether lipid metabolism
    100071038 (PLA2G4E)
   00590 Arachidonic acid metabolism
    100071038 (PLA2G4E)
   00591 Linoleic acid metabolism
    100071038 (PLA2G4E)
   00592 alpha-Linolenic acid metabolism
    100071038 (PLA2G4E)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    100071038 (PLA2G4E)
   04010 MAPK signaling pathway
    100071038 (PLA2G4E)
   04370 VEGF signaling pathway
    100071038 (PLA2G4E)
   04072 Phospholipase D signaling pathway
    100071038 (PLA2G4E)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    100071038 (PLA2G4E)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100071038 (PLA2G4E)
   04664 Fc epsilon RI signaling pathway
    100071038 (PLA2G4E)
   04666 Fc gamma R-mediated phagocytosis
    100071038 (PLA2G4E)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100071038 (PLA2G4E)
   04913 Ovarian steroidogenesis
    100071038 (PLA2G4E)
   04921 Oxytocin signaling pathway
    100071038 (PLA2G4E)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    100071038 (PLA2G4E)
  09156 Nervous system
   04724 Glutamatergic synapse
    100071038 (PLA2G4E)
   04726 Serotonergic synapse
    100071038 (PLA2G4E)
   04730 Long-term depression
    100071038 (PLA2G4E)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100071038 (PLA2G4E)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    100071038 (PLA2G4E)
Enzymes [BR:ecb01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     100071038 (PLA2G4E)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: cPLA2_C2 PLA2_B C2 CEP76-C2
Motif
Other DBs
NCBI-GeneID: 100071038
NCBI-ProteinID: XP_014589563
Ensembl: ENSECAG00000013837
VGNC: 21515
Position
1
AA seq 835 aa AA seqDB search
MLQRQMPAWVFHSLPDPSQTEDGRPSATCTLERGLFPCHLLTVRVIRMKNVRQADVVSQT
DCFVSLWLPTASHDRLRTRTISNCPNPEWNETFTFQIQSQVKNVLELSVCDEDTVTPDDH
LLTVLYDLTKLCFRKKTHVKFPLNPEGMEELEVEFLLEKSPDPPETLITNGVLVSRQVSC
LEVHAESRRRRKCGKQKDHLVTVTESFEHTQRILRCPEPCCPNPACFHYPKYFQSQIHVE
GPKSPWSCGLCCCCAHKKTGPICQPLDCLPDGQTVTLPVGENCELHMKSTPCPQTLDVRL
GFSLCSAELEFLQKRRLVVAEALKQVLQLEEDLQEDEVPLIAIMATGGGTRSMTAMYGHL
LGLQKLNILNCASYITGLSGATWTMATLYRDPDWSSKNLEPAIFEARRHVVKDKLPALFP
DQLSKFQEELRQRSQEGYKVTFTDFWGLLIEACLGDERNECKLSDQRAALCQGQNPLPIY
LTINVKDDVSNQDFREWCEFSPYEVGLQKYGAFIPTELFGSEFFMGRLMKRIPESRMCYM
LGLWSSIFSLNLLDAWNLSHTSEEFFYRWTRERVHDIEDEPLLPEIPKCDENILDTTVVI
PGSWLSNTFRSILTHRPFVSEFHNFLRGLQLHTDYLQNTEFSRWKDTVLDGFPNQLTASV
NHLCLLDTAFFVNSSYPPLLRPERKVDLIIHLNYCAGSQTKPMKQTCEYCTVQNIPFPKY
ELQEEEEKLKECYLMENLQEPDVPVVIFFPLINDTFQKYKAPGVERNPEELEQGQVDIYG
PKTPYATKELTYTEAAFDKLVKLSEYNILNNKDRLLQALRLAVEKKRRLKSQCPS
NT seq 2508 nt NT seq  +upstreamnt  +downstreamnt
atgctccagaggcagatgcccgcctgggtcttccactccctgccagacccaagccaaaca
gaagatggcaggccgtcggccacctgcaccttggagagggggctgtttccatgccacctg
ctgacagtgagggtcatccggatgaaaaatgtgcgacaggctgatgtggtgagccagaca
gactgctttgtgagcctctggctgcccaccgcctctcatgacaggctgaggactaggacc
atctccaactgccccaacccagagtggaatgaaaccttcaccttccagatccagagccaa
gtgaagaacgtgctagagctgagcgtctgcgatgaagacacagtgacaccagatgaccat
ctcttgacagttctctatgacctcaccaagctctgcttccgaaagaaaacccacgtgaag
ttcccactcaacccagagggcatggaggagctagaggtggagttcctgctggagaaaagt
cctgatccacctgagaccctcatcaccaatggcgtgctggtgtctcgacaggtctcctgc
ctggaggtgcatgcagaatccaggaggcggagaaagtgtggcaaacagaaggaccacctg
gtgacagtgacggagtcctttgagcacacccagcgcatcttgcgctgcccggagccctgc
tgcccaaaccctgcctgcttccactaccccaagtacttccagtcccagattcacgtggag
gggcccaagagtccatggagctgtgggctttgctgctgctgtgcgcacaagaaaaccggc
cccatctgccagcccctcgactgcctccccgacggccagacggtgaccctgcctgtgggc
gagaactgtgaactacacatgaagtctacaccctgcccccagacactggacgtgcggctg
ggcttcagcctgtgctcggcagagctggagttcctccagaagcggaggctggtggtggct
gaggcgctgaagcaggtgttgcagctggaggaggacctgcaggaggacgaggtaccactg
atagccatcatggccaccgggggtggaacaagatccatgacggccatgtacggccacctg
ctggggctgcagaagctgaacatcctgaactgtgccagctacatcactggcttgtcaggg
gccacctggaccatggctaccttgtaccgtgacccagactggtcctccaaaaacctggag
cctgccatctttgaggcacggaggcacgtggtcaaggacaagttgcctgccctgttccca
gaccagctctccaaattccaggaggagctccggcagcgcagccaggaagggtacaaggtc
acctttacagacttctggggcttgctgatcgaggcctgtctgggggacgagagaaatgaa
tgcaaactgtcagaccagcgtgctgctttgtgccagggccagaaccccctgcccatctac
ctcaccatcaatgtcaaggatgatgtaagcaaccaggatttcagagagtggtgcgagttc
tccccctacgaggtgggcctgcagaaatacggggccttcatccccaccgagctctttggc
tccgagttcttcatgggacggctgatgaagaggatcccagagtcgcggatgtgctacatg
ctaggtttgtggagcagcatcttctccctgaacctgcttgatgcctggaatctgtcccac
acctcggaggagtttttctacaggtggacaagggagagagtgcacgacatcgaagacgag
ccactcctgcctgaaatccccaaatgtgatgaaaacatcctggacaccacggtggtgatc
ccagggtcgtggctgtccaacacattccgcagcatcctcacccatcggcccttcgtgtct
gagttccacaacttcctgcgggggctgcagctgcacaccgactacctccagaacacagag
ttctccaggtggaaagacaccgtgctggacggtttcccaaaccagctgacggcgtctgtg
aaccacctgtgcctgctggacaccgcgttcttcgtcaactccagctacccgcccctcctc
cggcctgagagaaaagtcgacctcatcatccatctcaactactgtgccggatcccagaca
aagcccatgaagcagacctgtgagtactgcaccgtgcagaacatccccttccccaagtat
gagctgcaggaggaggaggagaagctcaaggagtgctaccttatggagaacctgcaggaa
cctgatgtccccgtcgtgattttcttccctctcatcaacgacaccttccagaagtacaag
gccccaggtgtggagcgaaaccccgaggagctggagcagggccaggtcgacatttatggc
cccaaaactccctacgccaccaaggagctgacgtacacagaggccgccttcgacaagctg
gtgaagctctccgagtacaacatcctgaataacaaggacaggctccttcaggccttgcgg
ctggcagtggagaagaagagacgcctgaagagccagtgtccctcctaa

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