KEGG   Escherichia coli O6 K2 H1 CFT073 (UPEC): c2553
Entry
c2553             CDS       T00106                                 
Symbol
hisI
Name
(GenBank) Histidine biosynthesis bifunctional protein hisIE
  KO
K11755  phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31]
Organism
ecc  Escherichia coli O6:K2:H1 CFT073 (UPEC)
Pathway
ecc00340  Histidine metabolism
ecc01100  Metabolic pathways
ecc01110  Biosynthesis of secondary metabolites
ecc01230  Biosynthesis of amino acids
Module
ecc_M00026  Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:ecc00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00340 Histidine metabolism
    c2553 (hisI)
Enzymes [BR:ecc01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.19  phosphoribosyl-AMP cyclohydrolase
     c2553 (hisI)
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.31  phosphoribosyl-ATP diphosphatase
     c2553 (hisI)
SSDB
Motif
Pfam: PRA-CH PRA-PH MazG
Other DBs
NCBI-ProteinID: AAN81008
UniProt: Q8FG47
Position
2384671..2385282
AA seq 203 aa
MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDRTIESGKVTFFSRTKQR
LWTKGETSGNFLNVVSIAPDCDNDTLLVLANPIGPTCHKGTSSCFGDTAHQWLFLYQLEQ
LLAERKSADPETSYTAKLYASGSKRIAQKVGEEGVETALAATVHDRFELTNEASDLMYHL
LVLLQDQDLDLTTVIENLRKRHQ
NT seq 612 nt   +upstreamnt  +downstreamnt
atgttaacagaacaacaacgtcgcgaactggactgggaaaaaaccgacggtctgatgccg
gtgattgtgcaacacgcggtatccggcgaagtgttaatgctgggctacatgaacccggaa
gccttagacagaaccatcgaaagcggtaaagttaccttcttctcgcgcactaaacagcga
ctgtggaccaaaggcgaaacctcgggcaatttcctcaatgtggtgagcattgcgccggac
tgcgacaacgacacgttactggtgctggcgaatcccatcgggccaacctgccacaaaggc
accagcagctgcttcggcgacaccgctcaccagtggctgttcctgtatcaactggaacaa
ctgctcgccgaacgtaaatctgccgacccggaaacctcctacaccgccaaactgtatgcc
agcggctccaaacgcattgcgcagaaagtgggcgaagaaggcgtggaaaccgcactggca
gcaacggtacatgaccgctttgagctgaccaacgaggcatctgacttgatgtatcacctg
ctggtgttgttgcaggatcaggatctggatttaacaacggtaattgagaacctgcgtaaa
cggcatcagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (3)   
   Pfam (3)   
All databases (25)   

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