KEGG   Escherichia coli O157 H7 EDL933 (EHEC): Z0126
Entry
Z0126             CDS       T00044                                 
Symbol
lpdA
Name
(GenBank) lipoamide dehydrogenase (NADH); component of 2-oxodehydrogenase and pyruvate complexes; L-protein of glycine cleavage complex
  KO
K00382  dihydrolipoyl dehydrogenase [EC:1.8.1.4]
Organism
ece  Escherichia coli O157:H7 EDL933 (EHEC)
Pathway
ece00010  Glycolysis / Gluconeogenesis
ece00020  Citrate cycle (TCA cycle)
ece00260  Glycine, serine and threonine metabolism
ece00280  Valine, leucine and isoleucine degradation
ece00310  Lysine degradation
ece00380  Tryptophan metabolism
ece00620  Pyruvate metabolism
ece00630  Glyoxylate and dicarboxylate metabolism
ece00640  Propanoate metabolism
ece00785  Lipoic acid metabolism
ece01100  Metabolic pathways
ece01110  Biosynthesis of secondary metabolites
ece01120  Microbial metabolism in diverse environments
ece01200  Carbon metabolism
ece01210  2-Oxocarboxylic acid metabolism
ece01240  Biosynthesis of cofactors
Module
ece_M00009  Citrate cycle (TCA cycle, Krebs cycle)
ece_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
ece_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
ece_M00621  Glycine cleavage system
Brite
KEGG Orthology (KO) [BR:ece00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    Z0126 (lpdA)
   00020 Citrate cycle (TCA cycle)
    Z0126 (lpdA)
   00620 Pyruvate metabolism
    Z0126 (lpdA)
   00630 Glyoxylate and dicarboxylate metabolism
    Z0126 (lpdA)
   00640 Propanoate metabolism
    Z0126 (lpdA)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    Z0126 (lpdA)
   00280 Valine, leucine and isoleucine degradation
    Z0126 (lpdA)
   00310 Lysine degradation
    Z0126 (lpdA)
   00380 Tryptophan metabolism
    Z0126 (lpdA)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    Z0126 (lpdA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ece04147]
    Z0126 (lpdA)
Enzymes [BR:ece01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.4  dihydrolipoyl dehydrogenase
     Z0126 (lpdA)
Exosome [BR:ece04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   Z0126 (lpdA)
SSDB
Motif
Pfam: Pyr_redox_2 Pyr_redox_dim Pyr_redox FAD_oxidored GIDA Pyr_redox_3 FAD_binding_2 HI0933_like AlaDh_PNT_C Thi4 NAD_binding_8 FAD_binding_3 DAO Lycopene_cycl FMO-like
Other DBs
NCBI-ProteinID: AAG54420
UniProt: P0A9P2
Position
132285..133709
AA seq 474 aa
MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHVA
KVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFT
GANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDPRIWDSTDALELKEVPERLLV
MGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRISKKFNLMLETKVTA
VEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAGVEVDDRGFIRVDKQ
LRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGKKHYFDPKVIPSIAYTEPEVAWV
GLTEKEAKEKGISYETATFPWAASGRAIASDCADGMTKLIFDKESHRVIGGAIVGTNGGE
LLGEIGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEVFEGSITDLPNPKAKKK
NT seq 1425 nt   +upstreamnt  +downstreamnt
atgagtactgaaatcaaaactcaggtcgtggtacttggggcaggccccgcaggttactcc
gctgccttccgttgcgctgatttaggtctggaaaccgtaatcgtagaacgttacaacacc
cttggcggtgtttgcctgaacgtcggctgtatcccttctaaagcactgctgcacgtagca
aaagttatcgaagaagccaaagcgctggctgaacacggtatcgtcttcggcgaaccgaaa
accgatatcgacaagattcgtacctggaaagagaaagtgatcaatcagctgaccggtggt
ctggctggtatggcgaaaggccgcaaagtcaaagtggtcaacggtctgggtaaatttacc
ggggctaacaccctggaagttgaaggtgagaacggtaaaaccgtgatcaacttcgacaac
gcgatcattgcagcgggttctcgcccgattcaactgccgtttattccgcatgaagatccg
cgtatctgggactctactgacgcgctggaactgaaagaagtaccagaacgcctgctggta
atgggtggcggtatcatcggtctggaaatgggcaccgtttaccacgcgctgggttcacag
attgacgtggttgaaatgttcgaccaggttatcccggcagctgacaaagacatcgttaaa
gtcttcaccaagcgtatcagcaagaaattcaacctgatgctggaaaccaaagttaccgcc
gttgaagcgaaagaagacggtatttatgtgacgatggaaggcaaaaaagcaccagctgaa
ccgcagcgttacgacgccgtgctggtagcgattggtcgtgtgccgaacggtaaaaacctc
gacgcaggcaaagctggcgtggaagttgacgaccgtggtttcatccgcgttgacaaacag
ctgcgtaccaacgtaccgcacatctttgctatcggcgatatcgtcggtcagccgatgctg
gcacacaaaggtgttcacgaaggtcacgttgccgctgaagttatcgccggtaagaaacac
tacttcgatccgaaagttatcccgtccatcgcctataccgaaccagaagttgcatgggta
ggtctgactgagaaagaagcgaaagagaaaggcatcagctatgaaaccgccaccttcccg
tgggctgcttctggtcgtgctatcgcttccgactgcgcagacggtatgaccaagctgatt
ttcgacaaagaatctcaccgtgtgatcggtggtgcgattgtcggtactaacggcggcgag
ctgctgggtgaaatcggcctggcaattgaaatgggttgtgatgctgaagacatcgcactg
accatccacgcgcacccgactctgcacgagtctgtgggcctggcggcagaagtgttcgaa
ggtagcattactgacctgccgaacccgaaagcgaagaagaagtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (23)   
   KEGG PATHWAY (16)   
   KEGG MODULE (7)   
Chemical substance (27)   
   KEGG COMPOUND (27)   
Chemical reaction (11)   
   KEGG ENZYME (1)   
   KEGG REACTION (10)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (15)   
   Pfam (15)   
All databases (85)   

Download RDF
DBGET integrated database retrieval system