KEGG   Escherichia coli O157 H7 EDL933 (EHEC): Z0684
Entry
Z0684             CDS       T00044                                 
Symbol
folD
Name
(GenBank) 5,10-methylene-tetrahydrofolate dehydrogenase; 5,10-methylene-tetrahydrofolate cyclohydrolase
  KO
K01491  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
Organism
ece  Escherichia coli O157:H7 EDL933 (EHEC)
Pathway
ece00670  One carbon pool by folate
ece00720  Other carbon fixation pathways
ece01100  Metabolic pathways
ece01120  Microbial metabolism in diverse environments
ece01200  Carbon metabolism
ece01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:ece00001]
 09100 Metabolism
  09102 Energy metabolism
   00720 Other carbon fixation pathways
    Z0684 (folD)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Z0684 (folD)
Enzymes [BR:ece01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     Z0684 (folD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     Z0684 (folD)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-ProteinID: AAG54886
UniProt: Q8XCT6
Position
complement(649021..649887)
AA seq 288 aa
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEE
VGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDV
DGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELL
LAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKV
VGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQGE
NT seq 867 nt   +upstreamnt  +downstreamnt
atggcagcaaagattattgacggtaaaacgattgcgcagcaggtgcgctctgaagttgct
caaaaagttcaggcgcgtattgcagccggactgcgggcaccaggactggccgttgtgctg
gtgggtagtaaccctgcatcgcaaatttatgtcgcaagcaaacgtaaggcttgtgaagaa
gtcgggttcgtctcccgctcttatgacctcccggaaaccaccagcgaagcggagctgctg
gagcttatcgatgcgctgaatgccgacaacaccatcgatggcattctggttcaactgccg
ttaccggcgggtattgataacgtcaaagtgctggaacgtatacacccggacaaagacgta
gacggtttccatccttataacgtcggtcgtctgtgccagcgcgcgccgcgtctgcgtccc
tgcaccccgcgcggtattgtcacgctgcttgagcgttacaacattgataccttcggcctc
aacgccgtggtgattggcgcatcgaatatcgttggccgcccgatgagcatggaactgttg
ctcgcaggttgcaccaccaccgtgactcaccgtttcactaaaaatytgcgtcaccacgta
gaaaatgccgatctgttgatmgttgccgtcggcaagccgggctttattcctggtgactgg
atcaaagaaggcgcaattgtgattgatgtcggcatcaaccgtytggaaaatggcaaagtt
gtgggcgacgtcgtgtttgaagacgcggctaaacgcgcctcatacattacgcctgttccg
ggcggcgttggcccgatgacggttgccacgctgattgaaaacacgctacaggcgtgcgtt
gaatatcatgatccacagggtgagtaa

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