KEGG   Escherichia coli O157 H7 EDL933 (EHEC): Z5569
Entry
Z5569             CDS       T00044                                 
Symbol
thiC
Name
(GenBank) thiamin biosynthesis, pyrimidine moiety
  KO
K03147  phosphomethylpyrimidine synthase [EC:4.1.99.17]
Organism
ece  Escherichia coli O157:H7 EDL933 (EHEC)
Pathway
ece00730  Thiamine metabolism
ece01100  Metabolic pathways
ece01240  Biosynthesis of cofactors
Module
ece_M00127  Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP
Brite
KEGG Orthology (KO) [BR:ece00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    Z5569 (thiC)
Enzymes [BR:ece01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.99  Other carbon-carbon lyases
    4.1.99.17  phosphomethylpyrimidine synthase
     Z5569 (thiC)
SSDB
Motif
Pfam: ThiC_Rad_SAM ThiC-associated
Other DBs
NCBI-ProteinID: AAG59191
UniProt: Q8X6X9
Position
complement(5071775..5073670)
AA seq 631 aa
MSATKLTRREQRAQAQHFIDTLEGTAFPNSKRIYITGTQPGVRVPMREIQLSPTLIGGSK
EQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKA
RLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEV
LRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQAL
EKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMA
KWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELT
KIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAM
SKARFEFRWEDQFNLALDPFTARAYHDETLPQESXKVAHXCSMCGPKFCSMKISQEVRDY
AAXQTIEMGIXDMSENFRAXGGEIYLRKEEA
NT seq 1896 nt   +upstreamnt  +downstreamnt
atgtctgcaacaaaactgacccgtcgcgaacaacgcgcccaggcccaacattttatcgac
accctggaaggcaccgcctttcccaactcaaaacgcatttatatcactggcacacaaccc
ggcgtgcgcgtgccgatgcgtgagatccagcttagcccgacgctaattggcggtagcaaa
gaacagccgcagtacgaagaaaacgaagcgattccggtctacgacacctccggcccgtat
ggcgatccgcagatcgccattaacgtgcagcaagggctggcaaaactacgccagccgtgg
atcgatgcgcgcggcgataccgaagaacttaccgtgcgcagttccgattacactaaagcg
cggctggcagatgatggcctcgacgagctgcgttttagcggcgtattaacgccaaaacgc
gccaaagcaggacgccgcgtcacacaactgcactacgcccgccagggcatcatcacaccg
gaaatggaattcatcgccatccgcgagaatatgggccgcgagcgcatccgtagcgaagtt
ttacgccaccagcatccgggaatgagctttggcgcacgtctgccggaaaatatcactgcg
gaatttgtccgtgatgaagttgctgccggacgtgcgattatcccggccaacattaatcat
ccggaatcggagccgatgattattggtcgcaatttcctggtaaaagttaacgccaatatc
ggcaactcggcggtcacctcttccatcgaagaagaagtggaaaagctggtatggtccacg
cgctggggagcggatacggtgatggatctctccaccggtcgctatattcacgaaacccgc
gagtggattttgcgtaacagcccggtgccgattggtacagtgccgatctaccaggcgctg
gagaaggttaatgggatcgccgaagaycttacctgggaagcgttccgcgacacgctgctg
gaacaggccgagcaaggtgtggattacttcactatccatgcgggggtgctgctgcgctat
gtgccgatgaccgcgaaacgcctgaccggtatcgtctcgcgcggcggttcgattatggcg
aaatggtgcctctcccatcatcaggaaaatttcctctatcaacacttccgcgaaatttgt
gaaatctgtgccgcttatgacgtttcgctgtcgctgggcgacggtctgcgccccggttct
attcaggacgccaacgatgaagcgcagtttgccgagctgcatacgctgggcgaactgaca
aaaatcgcctgggaatatgatgtgcaggtgatgattgaaggcccaggccacgtgccgatg
cagatgatccgccgcaatatgaccgaggagttagagcactgccacgaagcgccgttttac
actctggggccgctaactaccgatattgcgccgggctatgaccacttcacgtcggggatt
ggtgcggcgatgattggctggtttggctgcgcgatgctctgttacgtaacgccaaaagag
catctgggtctgcctaataaagaagatgttaagcaggggcttatcacctataagattgcc
gcccacgccgctgacctggcgaaagggcatccgggcgcacaaattcgcgataacgccatg
tcgaaagcccgcttcgaatttcgctgggaagaccagtttaatctggccctcgacccgttt
accgcccgcgcttatcacgatgaaaccctgccgcaagagtcangtaaagtcgcccatttn
tgctccatgtgtgggccgaaattctgctcgatgaaaatcagccaggaagtgcgtgattac
gccgccncgcaaactattgaaatgggaatancggatatgtcngagaacttccgtgccana
ggcggagaaatctacctgcgtaaggaggaagcgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (3)   
   KEGG MODULE (4)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   Pfam (2)   
All databases (26)   

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