KEGG   Escherichia coli O18 K1 H7 UTI89 (UPEC): UTI89_C0489
Entry
UTI89_C0489       CDS       T00338                                 
Symbol
acrB
Name
(GenBank) acridine efflux pump
  KO
K18138  multidrug efflux pump
Organism
eci  Escherichia coli O18:K1:H7 UTI89 (UPEC)
Pathway
eci01501  beta-Lactam resistance
eci01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:eci00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    UTI89_C0489 (acrB)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    UTI89_C0489 (acrB)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:eci02000]
    UTI89_C0489 (acrB)
   01504 Antimicrobial resistance genes [BR:eci01504]
    UTI89_C0489 (acrB)
Transporters [BR:eci02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   UTI89_C0489 (acrB)
Antimicrobial resistance genes [BR:eci01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    UTI89_C0489 (acrB)
SSDB
Motif
Pfam: ACR_tran SecD_SecF
Other DBs
NCBI-ProteinID: ABE05990
UniProt: Q1RF74
Position
complement(495385..498534)
AA seq 1049 aa
MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT
VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ
EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS
QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL
TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL
DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ
NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM
AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL
SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR
YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT
KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD
AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG
LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR
MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA
MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS
VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL
IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF
FVPVFFVVVRRRFSRKNEDIEHSHTVDHH
NT seq 3150 nt   +upstreamnt  +downstreamnt
atgcctaatttctttatcgatcgcccgatttttgcgtgggtgatcgccattatcatcatg
ttggcaggggggctggcgatcctcaaactgccggtggcgcaatatcctacgattgcaccg
ccggcagtaacgatctccgcctcctaccctggcgctgatgcgaaaacagtgcaggacacg
gtgacacaggttatcgaacagaatatgaacggtatcgataacctgatgtacatgtcctct
aacagtgactccacgggtaccgtgcagatcaccctgacctttgagtctggtactgatgcg
gatatcgcgcaggttcaggtgcagaacaaactgcagctggcgatgccgttgctgccgcaa
gaagttcagcagcaaggggtgagcgttgagaaatcatccagcagcttcctgatggttgtc
ggggttatcaacaccgatggcactatgacgcaggaggatatctctgactacgtggcagcg
aatatgaaagatgccatcagccgtacgtcgggcgtgggtgacgttcagttgttcggttca
cagtacgcgatgcgtatctggatgaacccgaatgaactgaacaaattccagctaacgccg
gttgatgtcattaccgccatcaaagcacagaacgctcaggttgcagctggtcagctcggt
ggtacgccgccggtgaaaggccaacagcttaacgcctctattattgctcagacgcgtctg
acctctactgaagagttcggcaaaatcctgctgaaagtgaatcaggatggttcccgcgtg
ctactgcgtgatgtggcgaaaattgagctgggtggtgagaactacgacatcatcgcagag
tttaacggccaaccggcttccggtctggggatcaagctggcgaccggtgcgaacgcgctg
gataccgctgcggcaatccgtgctgaactggcgaagatggaaccgttcttcccgtcgggt
ctgaaaattgtttacccgtatgacaccacaccgttcgtgaaaatctctattcacgaagtg
gtaaaaacgctggtcgaagcgatcatcctcgtgttcctggtaatgtatctgttcctgcag
aacttccgcgcgacgttgattccgactattgctgtaccggtggtattgctggggacattt
gccgtccttgccgcctttggcttctcgataaacacactaacgatgttcgggatggtactc
gccatcggcctgttggtggatgacgccatcgttgtagtagaaaacgttgagcgtgtaatg
gcagaagaaggtctgccaccgaaagaagctacgcgtaagtcgatggggcagattcagggc
gcgctggtgggtatcgcgatggtactgtcagcggtattcgtaccgatggccttcttcggc
ggttcgactggggcaatttatcgtcagttctccattaccattgtttcggcaatggcgctg
tcggtactggtggcgttgatcctgactccggcactctgtgcaaccatgctgaaaccgatt
gccaaaggcgatcacggcgaaggtaaaaaaggcttcttcggctggtttaaccgcatgttc
gagaagagcacgcaccactacaccgacagcgtaggcggtattctgcgcagtacagggcgt
tacctggtgctgtatctgatcatcgtggtcggcatggcctatctgttcgtgcgtctgcca
agctccttcttgccagatgaagaccagggcgtatttatgaccatggttcagctgccagca
ggtgcaacgcaggaacgtacgcagaaagtgctcaatgaggtaacgcattactatctgacc
aaagaaaagaacaacgttgagtcggtgttcgccgttaacggcttcggctttgcgggacgt
ggtcagaatacaggtattgcgttcgtttccttgaaggactgggccgatcgtccgggcgaa
gaaaacaaagttgaagcgattaccatgcgtgcaacacgtgctttctcgcaaatcaaagat
gcgatggttttcgcctttaacctgcccgcaatcgtggaactgggtaccgcaaccggcttt
gactttgagctgattgaccaggctggccttggtcacgaaaaactgactcaggcgcgtaac
cagttgcttgcagaagcagcgaagcaccctgatatgttgaccagcgtacgtccaaacggt
ctggaagataccccgcagtttaagattgatatcgaccaggaaaaagcgcaggcgctgggt
gtttctatcaacgacattaacaccactctgggcgctgcatggggcggtagctatgtgaac
gactttatcgaccgcggtcgtgtgaagaaagtttacgtcatgtcagaagcgaaataccgt
atgctgccggatgatatcggcgactggtatgttcgtgctgctgatggtcagatggtgccg
ttctcggcgttctcctcttctcgttgggagtacggttcgccgcgtctggaacgttacaac
ggcctgccatctatggaaatcttaggccaggcggcaccgggtaaaagtaccggtgaagca
atggagctgatggaacaactggcgagcaaactgcctaccggtgttggctatgactggacg
ggaatgtcctatcaggaacgtctctccggcaaccaggcgccttcactgtacgcgatttcg
ttgattgtcgtgttcctgtgtctggctgcgctgtacgagagctggtcgattccgttctcc
gttatgctggtcgttccgctgggggttatcggtgcgttgctggctgccaccttccgtggc
ctgaccaatgacgtttacttccaggtaggcctgctcacaaccattggtttgtcggcgaag
aacgcgatacttatcgtcgaattcgccaaagacttgatggataaagaaggtaaaggtctg
attgaagcgacgcttgatgcggtgcggatgcgtttacgcccaatcctgatgacctcgttg
gcgtttatcctcggcgttatgccgctggttatcagtactggtgctggttccggcgcgcag
aacgcagtaggtaccggtgtaatgggcgggatggtgaccgcaacggtactggcaatcttc
ttcgttccggtattctttgtggtggttcgccgccgctttagccgcaagaatgaagatatc
gagcacagccatactgtcgatcatcattga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (13)   

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