KEGG   Escherichia coli 55989 (EAEC): EC55989_2955
Entry
EC55989_2955      CDS       T00826                                 
Symbol
gshA
Name
(GenBank) gamma-glutamate-cysteine ligase
  KO
K01919  glutamate--cysteine ligase [EC:6.3.2.2]
Organism
eck  Escherichia coli 55989 (EAEC)
Pathway
eck00270  Cysteine and methionine metabolism
eck00480  Glutathione metabolism
eck01100  Metabolic pathways
eck01240  Biosynthesis of cofactors
Module
eck_M00118  Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:eck00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    EC55989_2955 (gshA)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    EC55989_2955 (gshA)
Enzymes [BR:eck01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.2  glutamate---cysteine ligase
     EC55989_2955 (gshA)
SSDB
Motif
Pfam: Glu_cys_ligase
Other DBs
NCBI-ProteinID: CAU98841
UniProt: B7LEA4
Position
complement(3025578..3027134)
AA seq 518 aa
MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTD
FAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYG
TSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGY
FRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLG
YTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELY
APIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALA
DAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLLQVGKDLFRDLKRVAQTL
DSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPL
EILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
NT seq 1557 nt   +upstreamnt  +downstreamnt
ttgatcccggacgtatcacaggcgctggcctggctggaaaaacatcctcaggcgttaaag
gggatacagcgtgggctggagcgcgaaactttgcgtgttaatgctgatggcacactggca
acaacaggtcatcctgaagcattaggttccgcactgacgcacaaatggattactaccgat
tttgcggaagcattgctggaattcattacaccagtggatggtgatattgaacatatgctg
acctttatgcgcgatctgcatcgttatacggcgcgcaatatgggtgatgagcggatgtgg
ccgttaagtatgccatgctacatcgcagaaggtcaggacatcgaactggcacagtacggc
acttctaacaccggacgctttaaaacgctgtatcgtgaagggctgaaaaatcgctacggc
gcgctgatgcaaaccatttccggcgtgcactacaatttctctttgccaatggcattctgg
caagcgaagtgcggtgatatctcgggcgctgatgccaaagagaaaatttctgcgggctat
ttccgcgttatccgcaattactatcgtttcggttgggtcattccttatctgtttggtgca
tctccggcgatttgttcttctttcctgcaaggaaaaccaacgtcgctgccgtttgagaaa
accgagtgcggtatgtattacctgccgtatgcgacctctcttcgtttgagcgatctcggc
tataccaataaatcgcaaagcaatcttggtattaccttcaacgatctttacgagtacgta
gcgggccttaaacaggcaatcaaaacgccatcggaagagtacgcgaagattggtattgag
aaagacggtaagaggctgcaaatcaatagcaacgtgctgcagattgaaaacgaactgtat
gcgccgattcgtccaaaacgcgttacccgcagcggcgagtcaccttctgatgcgctgtta
cgtggcggcattgaatatattgaagtgcgttcgctggacatcaacccgttctcgccgatt
ggtgtagatgaacagcaggtgcgattcctcgacctgtttatggtctggtgtgcgctggct
gatgcaccggaaatgagcagtagcgaacttgcctgtacgcgcgttaactggaaccgggtg
atccttgaaggtcgcaaaccgggcctgacgctgggtatcggctgcgaaaccgcgcagttc
ccgttactgcaggtgggtaaagatctgttccgcgatctgaaacgcgtcgcgcaaacgctg
gatagcattaacggcggcgaagcgtatcagaaagtgtgtgatgaactggttgcctgcttc
gataatcccgatctgactttctctgcccgtatcttaaggtctatgattgatactggtatt
ggcggaacaggcaaagcgtttgctgaagcgtaccgtaatctgctgcgtgaagagccgctg
gaaattctgcgcgaagaggattttgtagccgagcgcgaggcatctgaacgccgtcagcag
gaaatggaagccgcagataccgaaccgtttgcggtgtggctggaaaaacacgcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (1)   
   Pfam (1)   
All databases (25)   

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