KEGG   Escherichia coli SMS-3-5 (environmental): EcSMS35_2781
Entry
EcSMS35_2781      CDS       T00672                                 
Symbol
gabD
Name
(GenBank) succinate-semialdehyde dehydrogenase (NAD(P)(+))
  KO
K00135  succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
Organism
ecm  Escherichia coli SMS-3-5 (environmental)
Pathway
ecm00250  Alanine, aspartate and glutamate metabolism
ecm00310  Lysine degradation
ecm00350  Tyrosine metabolism
ecm00650  Butanoate metabolism
ecm00760  Nicotinate and nicotinamide metabolism
ecm01100  Metabolic pathways
ecm01120  Microbial metabolism in diverse environments
Module
ecm_M00027  GABA (gamma-Aminobutyrate) shunt
ecm_M00956  Lysine degradation, bacteria, L-lysine => succinate
Brite
KEGG Orthology (KO) [BR:ecm00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    EcSMS35_2781 (gabD)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    EcSMS35_2781 (gabD)
   00310 Lysine degradation
    EcSMS35_2781 (gabD)
   00350 Tyrosine metabolism
    EcSMS35_2781 (gabD)
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    EcSMS35_2781 (gabD)
Enzymes [BR:ecm01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.16  succinate-semialdehyde dehydrogenase [NAD(P)+]
     EcSMS35_2781 (gabD)
    1.2.1.20  glutarate-semialdehyde dehydrogenase
     EcSMS35_2781 (gabD)
    1.2.1.79  succinate-semialdehyde dehydrogenase (NADP+)
     EcSMS35_2781 (gabD)
SSDB
Motif
Pfam: Aldedh
Other DBs
NCBI-ProteinID: ACB15518
UniProt: B1LPD4
Position
2864889..2866337
AA seq 482 aa
MKLNDSNLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPKMGADETRAAIDAANRA
LPAWRALTAKERANILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFA
EEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLK
PASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQ
LMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQNG
VYDRFAEKLQQAVSKLHIGNGLEKGVTIGPLIDEKAVAKVEEHIADALEKGARVVCGGKA
HERGGNFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAYFYA
RDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYMCI
GL
NT seq 1449 nt   +upstreamnt  +downstreamnt
atgaaacttaacgacagtaacttattccgccagcaggcgttgattaacggggaatggctg
gacgccaacaatggcgaggtcatcgacgtcaccaatccggcgaacggcgacaagctgggt
agcgtacccaaaatgggcgctgatgaaacccgcgccgctatcgacgccgccaaccgcgct
ctgcccgcctggcgtgcgctcaccgccaaagaacgcgccaacattctgcgcaactggttc
aatttgatgatggagcatcaggacgatttagcgcgcctgatgaccctcgaacagggcaaa
ccactggccgaagcgaaaggcgaaatcagctacgccgcctcatttattgagtggtttgct
gaagaaggcaaacgtatttatggcgacaccattcccggtcatcaggccgataaacgcctg
attgttatcaagcagccgattggcgtcaccgcggctatcacgccgtggaacttcccggcg
gcgatgattacccgtaaagcaggtccggcgctggcggcaggctgcacgatggtgctgaag
cccgccagtcagacgccgttctctgcgctggcgctggcagaactggcgattcgcgcgggc
gttccggctggcgtgtttaacgtggtcaccggttcggcgggcgcggtcggtaacgaactg
accagcaacccgctggtgcgcaagctgtcgtttaccggctcgaccgaaattggccgccag
ttaatggaacagtgcgcgaaagacatcaagaaagtgtcgctggagctgggcggcaacgcg
ccgtttatcgtctttgacgatgccgacctcgacaaagccgtggaaggcgcactggcctcg
aaattccgcaacgccgggcaaacctgcgtctgcgccaaccgtttatacgtgcagaacggc
gtgtatgaccgctttgccgaaaaattgcagcaggcggtgagcaaactgcacatcggcaac
gggctggagaaaggcgtcaccatcgggccgctgatcgatgaaaaagcggtagcaaaagtg
gaagagcatattgccgatgcgctggagaaaggcgcgcgcgtggtttgcggcggtaaagca
catgaacgcggcggtaacttcttccagccgaccattctggtggacgttccggctaacgcc
aaagtgtcgaaagaagagacgttcggcccccttgccccgctattccgctttaaagatgaa
gccgatgtgattgcgcaggccaatgacaccgagtttggccttgccgcctatttctacgcc
cgtgatttaagccgcgtcttccgcgtgggcgaagcgctggagtacggcatcgtcggcatc
aataccggcattatttccaatgaagtggccccgttcggcggcattaaagcctcgggtctg
ggtcgtgaaggttcgaagtatggcatcgaagattacttagaaatcaaatatatgtgcatc
ggtctttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (7)   
   KEGG MODULE (3)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (1)   
   Pfam (1)   
All databases (34)   

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