KEGG   Escherichia coli K-12 MG1655: b0118
Entry
b0118             CDS       T00007                                 
Symbol
acnB
Name
(RefSeq) AcnB
  KO
K01682  aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
Organism
eco  Escherichia coli K-12 MG1655
Pathway
eco00020  Citrate cycle (TCA cycle)
eco00630  Glyoxylate and dicarboxylate metabolism
eco00640  Propanoate metabolism
eco00720  Other carbon fixation pathways
eco01100  Metabolic pathways
eco01110  Biosynthesis of secondary metabolites
eco01120  Microbial metabolism in diverse environments
eco01200  Carbon metabolism
eco01210  2-Oxocarboxylic acid metabolism
eco01230  Biosynthesis of amino acids
Module
eco_M00009  Citrate cycle (TCA cycle, Krebs cycle)
eco_M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
eco_M00012  Glyoxylate cycle
eco_M00982  Methylcitrate cycle
Brite
KEGG Orthology (KO) [BR:eco00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    b0118 (acnB)
   00630 Glyoxylate and dicarboxylate metabolism
    b0118 (acnB)
   00640 Propanoate metabolism
    b0118 (acnB)
  09102 Energy metabolism
   00720 Other carbon fixation pathways
    b0118 (acnB)
Enzymes [BR:eco01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.3  aconitate hydratase
     b0118 (acnB)
    4.2.1.99  2-methylisocitrate dehydratase
     b0118 (acnB)
SSDB
Motif
Pfam: Aconitase_2_N Aconitase_B_N Aconitase
Other DBs
NCBI-GeneID: 944864
NCBI-ProteinID: NP_414660
Pasteur: acnB
RegulonDB: RDBECOLIGNC02188
ECOCYC: EG12316
ASAP: ABE-0000411
UniProt: P36683
Structure
Position
131615..134212
AA seq 865 aa
MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEFLLDLLTNRVPPGVDEA
AYVKAGFLAAIAKGEAKSPLLTPEKAIELLGTMQGGYNIHPLIDALDDAKLAPIAAKALS
HTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRPALAEKLTVTVFKVTGETNTD
DLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVGPIKQIEALQQKGFPLAYVGDVV
GTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSN
LNMGDVIDVYPYKGEVRNHETGELLATFELKTDVLIDEVRAGGRIPLIIGRGLTTKAREA
LGLPHSDVFRQAKDVAESDRGFSLAQKMVGRACGVKGIRPGAYCEPKMTSVGSQDTTGPM
TRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVNTHHTLPDFIMNRGGVSLRPGDGVIH
SWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKM
QPGITLRDLVHAIPLYAIKQGLLTVEKKGKKNIFSGRILEIEGLPDLKVEQAFELTDASA
ERSAAGCTIKLNKEPIIEYLNSNIVLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEA
DADAEYAAVIDIDLADIKEPILCAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAA
GKLLDAHKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVA
DGATVVSTSTRNFPNRLGTGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDT
YRYLNFNQLSQYTEKADGVIFQTAV
NT seq 2598 nt   +upstreamnt  +downstreamnt
gtgctagaagaataccgtaagcacgtagctgagcgtgccgctgaggggattgcgcccaaa
cccctggatgcaaaccaaatggccgcacttgtagagctgctgaaaaacccgcccgcgggc
gaagaagaattcctgttagatctgttaaccaaccgtgttcccccaggcgtcgatgaagcc
gcctatgtcaaagcaggcttcctggctgctatcgcgaaaggcgaagccaaatcccctctg
ctgactccggaaaaagccatcgaactgctgggcaccatgcagggtggttacaacattcat
ccgctgatcgacgcgctggatgatgccaaactggcacctattgctgccaaagcactttct
cacacgctgctgatgttcgataacttctatgacgtagaagagaaagcgaaagcaggcaac
gaatatgcgaagcaggttatgcagtcctgggcggatgccgaatggttcctgaatcgcccg
gcgctggctgaaaaactgaccgttactgtcttcaaagtcactggcgaaactaacaccgat
gacctttctccggcaccggatgcgtggtcacgcccggatatcccactgcacgcgctggcg
atgctgaaaaacgcccgtgaaggtattgagccagaccagcctggtgttgttggtccgatc
aagcaaatcgaagctctgcaacagaaaggtttcccgctggcgtacgtcggtgacgttgtg
ggtacgggttcttcgcgtaaatccgccactaactccgttctgtggtttatgggcgatgat
attccacatgtgccgaacaaacgcggcggtggtttgtgcctcggcggtaaaattgcaccc
atcttctttaacacgatggaagacgcgggtgcactgccaatcgaagtcgacgtctctaac
ctgaacatgggcgacgtgattgacgtttacccgtacaaaggtgaagtgcgtaaccacgaa
accggcgaactgctggcgaccttcgaactgaaaaccgacgtgctgattgatgaagtgcgt
gctggtggccgtattccgctgattatcgggcgtggcctgaccaccaaagcgcgtgaagca
cttggtctgccgcacagtgatgtgttccgtcaggcgaaagatgtcgctgagagcgatcgc
ggcttctcgctggcgcaaaaaatggtaggccgtgcctgtggcgtgaaaggcattcgtccg
ggcgcgtactgtgaaccgaaaatgacttctgtaggttcccaggacaccaccggcccgatg
acccgtgatgaactgaaagacctggcgtgcctgggcttctcggctgacctggtgatgcag
tctttctgccacaccgcggcgtatccgaagccagttgacgtgaacacgcaccacacgctg
ccggacttcattatgaaccgtggcggtgtgtcgctgcgtccgggtgacggcgtcattcac
tcctggctgaaccgtatgctgctgccggataccgtcggtaccggtggtgactcccatacc
cgtttcccgatcggtatctctttcccggcgggttctggtctggtggcgtttgctgccgca
actggcgtaatgccgcttgatatgccggaatccgttctggtgcgcttcaaaggcaaaatg
cagccgggcatcaccctgcgcgatctggtacacgctattccgctgtatgcgatcaaacaa
ggtctgctgaccgttgagaagaaaggcaagaaaaacatcttctctggccgcatcctggaa
attgaaggtctgccggatctgaaagttgagcaggcctttgagctaaccgatgcgtccgcc
gagcgttctgccgctggttgtaccatcaagctgaacaaagaaccgatcatcgaatacctg
aactctaacatcgtcctgctgaagtggatgatcgcggaaggttacggcgatcgtcgtacc
ctggaacgtcgtattcagggcatggaaaaatggctggcgaatcctgagctgctggaagcc
gatgcagatgcggaatacgcggcagtgatcgacatcgatctggcggatattaaagagcca
atcctgtgtgctccgaacgacccggatgacgcgcgtccgctgtctgcggtacagggtgag
aagatcgacgaagtgtttatcggttcctgcatgaccaacatcggtcacttccgtgctgcg
ggtaaactgctggatgcgcataaaggtcagttgccgacccgcctgtgggtggcaccgcca
acccgtatggacgccgcacagttgaccgaagaaggctactacagcgtcttcggtaagagt
ggtgcgcgtatcgagatccctggctgttccctgtgtatgggtaaccaggcgcgtgtggcg
gacggtgcaacggtggtttccacctctacccgtaacttcccgaaccgtctgggtactggc
gcgaatgtcttcctggcttctgcggaactggcggctgttgcggcgctgattggcaaactg
ccgacgccggaagagtaccagacctacgtggcgcaggtagataaaacagccgttgatact
taccgttatctgaacttcaaccagctttctcagtacaccgagaaagccgatggggtgatt
ttccagactgcggtttaa

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Gene (77)   
   RefGene (70)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ASAP (1)   
   ECOCYC (1)   
   OC (1)   
   PASTEUR (1)   
   REGULONDB (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (1)   
   PDB (1)   
Protein domain (3)   
   Pfam (3)   
All databases (84)   

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